Top 100 Drugs Of Choice For Different Diseases

Drugs of choice are categorized on the basis of diseases. The following are the most important classes of drugs used as a first choice in the treatment of different diseases.

Drugs Of Choice List in pregnancy

(1)Chloroquine

  • Drug of choice for malaria in pregnancy

(2) Alpha-Methyldopa

  • DoC for hypertension in pregnancy

(3) Heparin

  • For anticoagulation in pregnancy

(4) Labetalol

  • For the hypertensive crisis in pregnant women.

(5) Acetaminophen

  • Analgesic DOC

(6) Phenobarbitone

  • For epilepsy in pregnant women.

(7) Doxylamine & Pyridoxine

  • For nausea in pregnancy

Drugs Of Choice List in infections

(8) Penicillin G

Drug of choice in

  • Septicemia,
  • Meningitis,
  • Pericarditis,
  • Endocarditis and
  • Severe pneumonia.

(9) Ampicillin

Drug of choice in

  • Listeria,
  • Enterococcus faecalis.

(10) Vancomycin

Drug of choice for

  • MRSA,
  • Coagulase-negative Staphylococcus,
  • Enterococcus faecium.

(11) Erythromycin

Drug of choice for

  • Corynebacterium

(12) Doxycycline

  • Bacillus anthracis,
  • Borrelia burgdorferi, B.Recurrentis.
  • Chalmydia & Rickettsiae.

(13) Cotrimoxazole

Drug of choice in

  • Nocardia

(14) Azithromycin

Drug of choice in

  • Hemophilus ducreyi &
  • Mycoplasma.

(15) Ceftriaxone

Drug of choice for

  • Proteus,
  • E.coli,
  • Salmonella

(16) Ciprofloxacin (Ciproxin)

Drug of choice for

  • Urinary Tract Infection

(17) Metronidazole

Drug of choice for

  • Bacteriocides

(18) Ceftazidime

DOC for

  • Burkholderia pseudomallei

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Drugs Of Choice List for various types of seizures

(19) Valproate

Drug of choice for

  • Tonic seizures
  • Absence seizures
  • Grand mal (GTCS)
  • Clonic seizures
  • Atonic seizures
  • Myoclonic seizures

(20) Carbamazepine

  • Partial seizures

(21) Vigabatrin

  • Infantile spasm with tuberous sclerosis

(22) ACTH

  • Infantile spasm

(23) Lorazepam (IV)

  • Status epilepticus

(24) Diazepam

  • Febrile seizures

(25) Magnesium Sulphate

  • Seizure in eclampsia

Drugs Of Choice List in poisoning

(26) Physostigmine

  • Atropine,
  • Belladonna  &
  • Dhatura poisoning

(27) Atropine

  • Carbamate,
  • Early mushroom poisoning,
  • Organophosphate poisoning.

(28) Flumazenil

  • Benzodiazepine poisoning

(29) Acetylcysteine

  • Acetaminophen poisoning

(30) Naloxone

  • Opioid poisoning

(31) Deferiprone

  • Chronic iron poisoning

(32) Desferrioxamine

  • Acute iron poisoning

(33) Glucagon

  • Beta-blockers poisoning

(34) Amyl nitrate

  • Cyanide poisoning

Drugs Of Choice List in bronchial asthma

(35) Salbutamol

Salbutamol is the drug of choice for

  • An acute attack of bronchial asthma in normal patient and pregnant women.
  • Exercise & Aspirin-induced acute attack of bronchial asthma.

(36) Ipratropium

  • An acute attack of bronchial asthma during labor.
  • An acute attack of bronchial asthma on beta-blocker therapy.

(37) Corticosteroids

  • Prophylaxis of bronchial asthma,
  • Exercise-induced, and
  • Aspirin-induced asthma.

Drugs Of Choice List In Antimicrobials Prophylaxis

(38) Ampicillin

  • Group B streptococcus infection

(39) Amoxicillin

  • Endocarditis and Otitis media

(40) Azithromycin

  • Mycobacterium avium complex (MAC) Pertussis

(41) Benzathine penicillin

  • Rheumatic fever

(42) Procaine Penicillin

  • Gonorrhea and syphilis

(43) Tetracycline

  • Rickettsial infection and plague.

(44) Cefazoline

  • Surgical Prophylaxis

(45) Doxycycline

  • Anthrax

(46) Trimethoprim and sulphamethoxazole

  • Toxoplasmosis,
  • Pneumocystis service UTI

(47) Rifampicin

  • Hemophilus influenza type B.

(48) Oseltamivir

  • Influenza Type A & B.

Anesthetic Drugs Of Choice List

(49) Propofol

  • Daycare

(50) Sevoflurane

  • Congenital heart disease,
  • ASD,VSD,PDA

(51) Etomidate

  • Ischemic heart disease

(52) Ketamine

  • Asthma and COPD
  • Shock
  • CHF, and
  • congenital heart disease (Right to left shunt)

(53) Thiopentone

  • Epilepsy
  • Thyrotoxicosis

(54) Methohexitone

  • Electroconvulsive therapy

(55) Isoflurane

  • Cardiac surgery
  • Neurosurgery
  • For producing deliberate hypotension

Drugs Of Choice List in Endocrinological Disorders

(56) Insulin

  • Type 1 DM
  • Diabetes Mellitus in pregnancy.
  • Diabetic Ketoacidosis.
  • Uncontrolled DM.

(57) Metformin

  • Type 2 DM
  • Diabetes mellitus in obesity

(58) Sildenafil

  • Erectile Dysfunction

(59) Hydrocortisone

  • Acute and chronic adrenal insufficiency.

(60) Nateglinide

  • Postprandial hyperglycemia.

(61) Methotrexate

  • Ectopic pregnancy

(62) Oxytocin

  • Postpartum hemorrhage
  • Induction of labor

(63) Cabergoline

  • Acromegaly
  • Hyperprolactinemia.

(64) Finasteride

  • Anogenital alopecia.

(65) Alendronate

  • Osteoporosis

Drugs of choice in fungal infections

(66) Amphotericin B

Amphotericin B is the drug of choice in

  • Meningeal histoplasmosis
  • Endocarditis by candida
  • Sever or CNS blastomycosis
  • Induction  cryptococcal meningitis(For 2 weeks)
  • Exserohium

(67) Fluconazole

  • Candida albicans
  • Maintainance in cryptococcal meningitis

(68) itraconazole

  • Nonmeningeal histoplasmosis
  • Sporotrichosis
  • Para Coccidioidomycosis
  • Mild or non-CNS blastomycosis
  • Chromoblastomycosis
  • Penicillium mameffei

(69) Prednisolone+itraconazole/Voriconazole

  • Allergic bronchopulmonary aspergillosis.

(70) Caspofungin

  • Candida glabrate, and
  • Candida krusei.

Drugs of choice in gastrointestinal disorders

(71) PPIs (Proton Pump Inhibitors)

  • Gastric ulcer,
  • Duodenal ulcer,
  • stress ulcer,
  • NSAIDs-induced ulcer.
  • GERD,& Zollinger Ellison syndrome.

(72) Metoclopramide

  • A migraine-associated or drug or disease-associated vomiting

(73) Domperidone

  • Levodopa-induced vomiting

(74) Ondansetron

  • Postoperative or radiation-induced vomiting

(75) 5HT3 antagonist

  • Cisplatin-induced early vomiting

(76) Lactulose

  • Hepatic encephalopathy

(77) Methylnaltrexone

  • Opioid-induced constipation

(78) Octreotide

  • Diarrhea in carcinoid syndrome

Drugs of choice in Hematological Disorders

(79) Warfarin

  • DVT prophylaxis
  • Chronic atrial fibrillation in mitral stenosis,
  • Advanced kidney disease, and
  • mechanical prosthetic heart valves

(80) Heparin+Warfarin

  • Initiation of therapy in DVT.

(81) Vitamin K

  • Warfarin overdose

(82) Protamine

  • Heparin overdose

Drugs of Choice in Hypertension

(83) Thiazide diuretics

  • Hypertension

(84) Prazosin

  • Hypertension With BPH

(85) Beta-Blockers

  • Hypertension with ischemic heart disease.(Angina)

(86) ACE inhibitors

  • Hypertension with chronic kidney diseases.

(87) Alpha methylDopa

  • Hypertension in pregnancy

(88) Phentolamine

  • Hypertensive emergencies with cheese reaction

(89) Nitroprusside+Esmolol

  • Hypertensive emergencies in aortic dissection.

(90) Labetalol

  • Hypertensive emergencies in pregnancy.

Drugs of choice in shock

(91) Adrenaline

  • Anaphylactic shock

(92) Dopamine or noradrenaline

  • Cardiogenic shock

(93) Phenylephrine

  • Distributive shock

(94) Prazosin

  • Secondary shock

(95) Dopamine

  • Shock with oliguria

(96) Corticosteroids

  • Shock due to adrenal insufficiency

Drugs of choice For viral diseases

(97) Ribavirin

  • Viral hemorrhagic fever
  • Measles
  • Respiratory syncytial virus(in high-risk patient

(98) Zanamivir

  • Oseltamivir-resistant influenza
  • Oseltamivir
  • Seasonal influenza and avian influenza (bird flu)

(99) Acyclovir

  • Herpes simplex and varicella.
  • Valacyclovir
  • Acute herpes zoster.

(100) Gancyclovir

  • Cytomegalovirus retinitis.

Drugs Of choice


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8 thoughts on “Top 100 Drugs Of Choice For Different Diseases

  1. Thanks for your efforts but a lot of therapeutic areas you mentioned have now more preferable drugs than what you mentioned.

  2. Phenobarbitol is Antiepileptic DOC in pregnancy?
    Isn’t the DOC is lamotrignine or laveteracetam?

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