In narcotics, drugs of choice means an illicit drug a person is addicted to while in medical it is the first line treatment for a medical condition. In this article, we have categorised different drugs on the basis of diseases. The following are the most important classes of drugs used as a first choice in the treatment of different diseases.
Drugs Of Choice List in pregnancy
(1) Chloroquine [1]
- Drug of choice for malaria in pregnancy
(2) Alpha-Methyldopa
- DoC for hypertension in pregnancy
(3) Heparin
- For anticoagulation in pregnancy
(4) Labetalol
- For the hypertensive crisis in pregnant women.
(5) Acetaminophen
- Analgesic DOC
(6) Phenobarbitone
- For epilepsy in pregnant women.
(7) Doxylamine & Pyridoxine
- For nausea in pregnancy
Drugs Of Choice List in infections
(8) Penicillin G
Drug of choice in
- Septicemia,
- Meningitis,
- Pericarditis,
- Endocarditis and
- Severe pneumonia.
(9) Ampicillin
Drug of choice in
- Listeria,
- Enterococcus faecalis.
(10) Vancomycin
Drug of choice for
- MRSA,
- Coagulase-negative Staphylococcus,
- Enterococcus faecium.
(11) Erythromycin
Drug of choice for
- Corynebacterium
(12) Doxycycline
- Bacillus anthracis,
- Borrelia burgdorferi, B.Recurrentis.
- Chalmydia & Rickettsiae.
(13) Cotrimoxazole
Drug of choice in
- Nocardia
(14) Azithromycin
Drug of choice in
- Hemophilus ducreyi &
- Mycoplasma.
(15) Ceftriaxone
Drug of choice for
- Proteus,
- E.coli,
- Salmonella
Drug of choice for
- Urinary Tract Infection.
- You can also use nitrofurantoin or oral cephalosporins, or fosfomycin. [2]
(17) Metronidazole:
It is an imidazole that is used for the treatment of antibacterial and antiprotozoal infections, including bacterial vaginosis and antibiotic-associated colitis.
Drug of choice for
- Trichomonas vaginalis. [3]
- Bacteriocides.
(18) Ceftazidime
DOC for
- Burkholderia pseudomallei
Related Article
Drugs Of Choice List for various types of seizures
(19) Valproate
Drug of choice for
- Tonic seizures
- Absence seizures
- Grand mal (GTCS)
- Clonic seizures
- Atonic seizures
- Myoclonic seizures [4]
(20) Carbamazepine
- Partial seizures
(21) Vigabatrin
- Infantile spasm with tuberous sclerosis
(22) ACTH
- Infantile spasm
(23) Lorazepam (IV)
- Status epilepticus
(24) Diazepam
- Febrile seizures
(25) Magnesium Sulphate
- Seizure in eclampsia
Drugs Of Choice List in poisoning
(26) Physostigmine
- Atropine,
- Belladonna &
- Dhatura poisoning
(27) Atropine
- Carbamate,
- Early mushroom poisoning,
- Organophosphate poisoning.
(28) Flumazenil
- Benzodiazepine poisoning
(29) Acetylcysteine
- Acetaminophen poisoning
(30) Naloxone
- Opioid poisoning
(31) Deferiprone
- Chronic iron poisoning
(32) Desferrioxamine
- Acute iron poisoning
(33) Glucagon
- Beta-blockers poisoning
(34) Amyl nitrate
- Cyanide poisoning
Drugs Of Choice List in bronchial asthma
(35) Salbutamol
Salbutamol is the drug of choice for
- An acute attack of bronchial asthma in normal patients and pregnant women.
- Exercise & Aspirin-induced acute attack of bronchial asthma.
(36) Ipratropium
- An acute attack of bronchial asthma during labor.
- An acute attack of bronchial asthma on beta-blocker therapy.
(37) Corticosteroids
- Prophylaxis of bronchial asthma,
- Exercise-induced, and
- Aspirin-induced asthma.
Drugs Of Choice List In Antimicrobials Prophylaxis
(38) Ampicillin
- Group B streptococcus infection
(39) Amoxicillin
- Endocarditis and Otitis media
(40) Azithromycin
- Mycobacterium avium complex (MAC) Pertussis
(41) Benzathine penicillin
- Rheumatic fever
(42) Procaine Penicillin
- Gonorrhea and syphilis
(43) Tetracycline
- Rickettsial infection and plague.
(44) Cefazoline
- Surgical Prophylaxis
(45) Doxycycline
- Anthrax
(46) Trimethoprim and sulphamethoxazole
- Toxoplasmosis,
- Pneumocystis service UTI
(47) Rifampicin
- Hemophilus influenza type B.
(48) Oseltamivir
- Influenza Type A & B.
Anesthetic Drugs Of Choice List
(49) Propofol
- Daycare
(50) Sevoflurane
- Congenital heart disease,
- ASD,VSD,PDA
(51) Etomidate
- Ischemic heart disease
(52) Ketamine
- Asthma and COPD
- Shock
- CHF, and
- congenital heart disease (Right to left shunt)
(53) Thiopentone
- Epilepsy
- Thyrotoxicosis
(54) Methohexitone
- Electroconvulsive therapy
(55) Isoflurane
- Cardiac surgery
- Neurosurgery
- For producing deliberate hypotension
Drugs Of Choice List in Endocrinological Disorders
(56) Insulin
- Type 1 DM
- Diabetes Mellitus in pregnancy.
- Diabetic Ketoacidosis.
- Uncontrolled DM.
(57) Metformin
- Type 2 DM
- Diabetes mellitus in obesity
(58) Sildenafil
- Erectile Dysfunction
(59) Hydrocortisone
- Acute and chronic adrenal insufficiency.
(60) Nateglinide
- Postprandial hyperglycemia.
(61) Methotrexate
- Ectopic pregnancy
(62) Oxytocin
- Postpartum hemorrhage
- Induction of labor
(63) Cabergoline
- Acromegaly
- Hyperprolactinemia.
(64) Finasteride
- Anogenital alopecia.
(65) Alendronate
- Osteoporosis
Drugs of choice in fungal infections
(66) Amphotericin B
Amphotericin B is the drug of choice in
- Meningeal histoplasmosis
- Endocarditis by candida
- Sever or CNS blastomycosis
- Induction cryptococcal meningitis(For 2 weeks)
- Exserohium
(67) Fluconazole
- Candida albicans
- Maintainance in cryptococcal meningitis
(68) Itraconazole
- Nonmeningeal histoplasmosis
- Sporotrichosis
- Para Coccidioidomycosis
- Mild or non-CNS blastomycosis
- Chromoblastomycosis
- Penicillium mameffei
(69) Prednisolone+itraconazole/Voriconazole
- Allergic bronchopulmonary aspergillosis.
(70) Caspofungin
- Candida glabrate, and
- Candida krusei.
Drugs of choice in gastrointestinal disorders
(71) PPIs (Proton Pump Inhibitors)
- Gastric ulcer,
- Duodenal ulcer,
- stress ulcer,
- NSAIDs-induced ulcer.
- GERD,& Zollinger Ellison syndrome.
(72) Metoclopramide
- A migraine-associated or drug or disease-associated vomiting
(73) Domperidone
- Levodopa-induced vomiting
(74) Ondansetron
- Postoperative or radiation-induced vomiting
(75) 5HT3 antagonist
- Cisplatin-induced early vomiting
(76) Lactulose
- Hepatic encephalopathy
(77) Methylnaltrexone
- Opioid-induced constipation
(78) Octreotide
- Diarrhea in carcinoid syndrome
Drugs of choice in Hematological Disorders
(79) Warfarin
- DVT prophylaxis
- Chronic atrial fibrillation in mitral stenosis,
- Advanced kidney disease, and
- mechanical prosthetic heart valves
(80) Heparin+Warfarin
- Initiation of therapy in DVT.
(81) Vitamin K
- Warfarin overdose
(82) Protamine
- Heparin overdose
Drugs of Choice in Hypertension
(83) Thiazide diuretics
- Hypertension
(84) Prazosin
- Hypertension With BPH
(85) Beta-Blockers
- Hypertension with ischemic heart disease. (Angina)
(86) ACE inhibitors
- Hypertension with chronic kidney diseases.
(87) Alpha methylDopa
- Hypertension in pregnancy
(88) Phentolamine
- Hypertensive emergencies with cheese reaction
(89) Nitroprusside + Esmolol
- Hypertensive emergencies in aortic dissection.
(90) Labetalol
- Hypertensive emergencies in pregnancy.
Drugs of choice in shock
(91) Adrenaline
- Anaphylactic shock
(92) Dopamine or noradrenaline
- Cardiogenic shock
(93) Phenylephrine
- Distributive shock
(94) Prazosin
- Secondary shock
(95) Dopamine
- Shock with oliguria
(96) Corticosteroids
- Shock due to adrenal insufficiency
Drugs of choice For viral diseases
(97) Ribavirin
- Viral hemorrhagic fever
- Measles
- Respiratory syncytial virus(in high-risk patient
(98) Zanamivir
- Oseltamivir-resistant influenza
- Oseltamivir
- Seasonal influenza and avian influenza (bird flu)
(99) Acyclovir
- Herpes simplex and varicella.
- Valacyclovir
- Acute herpes zoster.
(100) Gancyclovir
- Cytomegalovirus retinitis.
Learn more about medicine and drugs ⇐here.
References
- Pregnancy outcome following first trimester exposure to chloroquine [Cited 11/29/2020] [Available: https://pubmed.ncbi.nlm.nih.gov/2029276/#:~:text=Although%20the%20use%20of%20chloroquine,during%20pregnancy%20has%20been%20controversial.]
- THE CHOICE OF ANTIBACTERIAL DRUGS. [Cited 11/29/2020] [Available https://journals.lww.com/infectdis/fulltext/2001/12000/the_choice_of_antibacterial_drugs.21.aspx
- Metronidazole. [Cited 11/29/2020] [Available https://www.sciencedirect.com/topics/neuroscience/metronidazole]
- Valproate Efficacy in Absence Seizures Is Hard to Beat: Lamotrigine Comes Close [Cited 11/29/2020] [Available https://www.ncbi.nlm.nih.gov/pmc/articles/PMC1176308/]
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Great topic
Excellent thank you so much for this Informations
Thanks so much
Thanks for your efforts but a lot of therapeutic areas you mentioned have now more preferable drugs than what you mentioned.
Phenobarbitol is Antiepileptic DOC in pregnancy?
Isn’t the DOC is lamotrignine or laveteracetam?