Prevagen Review—Is It Safe To Take Prevagen?

Quick Prevagen Review

  • Prevagen is a natural dietary supplement said to be the secret to a healthy brain, sharper mind, and clearer thinking. This supplement promises improved memory that will boost your ability to think more clearly. 
  • Recent studies have uncovered that, while Prevagen appears to be a safe dietary supplement, there is still the need for more evidence confirming its efficacy as it may not fully absorb into our bodies.
  • Prevagen and all other nootropic supplements are not FDA-approved and shouldn’t be used if you have serious brain problems, including Alzheimer’s. As always, consult your healthcare provider before taking any new supplements.
  • High-quality alternatives include BrainPill, Focus Factor, Neuriva, Qualia Mind, Natrol Cognium, Mind Lab Pro, and other such Nootropics.

Do you want to get good exam scores, be attractive in your presentation and remember names and places?

You likely have heard about Prevagen— a novel over-the-counter dietary supplement claimed to boost your brain performance, improve memory, sharpen the mind, support clearer thinking, and aid with mild memory problems associated with aging.

It is a popular memory-enhancing supplement that has made an incredible impact, evidenced by the staggering 17000+ positive Prevagen reviews on Amazon and over 500 customer testimonials from Walmart. It’s obviously making waves in the nootropic space.

Depending on the variants you are purchasing, the prices range from $39.95 to $100. Prevagen has something for everyone – from regular strength to extra and even more potent versions. Its latest offering contains a whopping 40mg of Apoaequorin per serving, providing the brain with superior support.

The best price for regular strength on Amazon is 39.95$, 50$ for extra strength, and $98.94 for professional strength. The professional formula contains more active ingredients and is more expensive as it contains the more active ingredient.

  • Prevagen extra strength 60 capsules
  • Prevagen regular strength 60 capsules
  • Prevagen Professional 40mg
  • Prevagen Chewable Mixed Berry Flavor 10mg.

If you’re considering Prevagen, the cost may be a deciding factor. But is this highly-priced brain supplement really worth the money or just another scam?

Let’s explore whether Prevagen is worth your money or whether it’s just another run-of-the-mill expenses scam supplement. In this Prevagen Review, we will tell you the science behind each ingredient, its use in brain-boosting, and what makes it unique from its competitors, and at the end of this buyer’s guide, I will give my opinion if it’s worth your hard-earned money or not?

Why should you trust us?

Our expert team of pharmacists and Ph.D. scholars has all the knowledge you need to make an informed decision about nootropics on the market today. We comb through trusted sources online, verified customer reviews from Amazon, and our honest opinion based on quality assurance tests and clinical studies – leaving out any marketing buzzwords so that you can be confident in what we recommend. Our mission is to provide only high-quality products that positively impact your daily life at prices that won’t break the bank.

Let’s have a quick overview first.

⭐ Our Rating

3.8 ★★★★

✅ Pros Unique ingredients, cGMP-approved facility, Best Seller, Highly rated, third party tested, comes with money back guarantee.
❌ Cons There is a lawsuit against the company, it’s expensive. Limited research.
Core Ingredients Apoaequorin, Vitamin D3
Best Place to buy
Price Starting $104


Prevagen Review (Quick)

Full Name: Prevagen Improves Memory

Company Name: Quincy Bioscience

Amazon Rating: 4.5/5 (Reviews: 17200+)

Walmart Rating: 4/5 (Reviews: 500+)

(May change with time)

Prices At Amazon: $85

In Stock

Price At Walmart: $109.90

In Stock

Price At Prevagen Website

In Stock

My Unbiased Prevagen Review

Our research team gave us all the information they found about the ingredients, their side effects, benefits, studies on Apoaeaquorin and Vitamin D, where to buy Prevagen, and more. 

Let’s dive deep into this buyer’s guide;

Prevagen reviews
Unbiased and honest Prevagen reviews

About The Company

Prevagen is made by Quincy Bioscience—a biotech company focused on the discovery and development of new technologies to support cognitive function and other normal health challenges associated with aging.

Quincy Bioscience based in Madison, Wisconsin, United States is founded by Mark Underwood and Michael Beaman in 2004 with a mission to discover and develop new technologies that can help improve cognitive function.

The company is not accredited by the Better Business Bureau (BBB), and there are no customer complaints. However, the BBB rating of Quincy Bioscience is A+.

What is Prevagen?

Prevagen is a nootropic supplement composed of unique combinations. It contains Apoaequorin and Vitamin D as core ingredients, allowing users to reduce mild memory loss associated with aging while enhancing brain function. As such, Prevagen offers support for healthy memories among growing adults – unlocking the potential that constitutes cognitive capability.

According to the label, the supplement can deliver the following benefits.

  • Supports healthy brain function.
  • Reduces brain fog and clear thinking,
  • Sharpen the mind and improve cognition.

Note that this review is based on our honest opinions and hours of research on this product. We will tell you whether it’s worth the money or a waste.

Prevagen ingredients (7 Out Of 10)

The idea behind Prevagen is calcium regulation in the brain, which is why they have formulated this product from two active constituents that are said to improve calcium levels in the brain. Let’s have a look at the Prevagen ingredients;


The key ingredient is a calcium-binding protein obtained from jellyfish, which could benefit those who struggle with forgetfulness or recall issues. This protein was first discovered in jellyfish, but the Apoaequorin found in Prevagen is actually synthetically produced by a genetically modified bacteria. In addition, preliminary research has shown that taking 10 mg of Apoaequorin per day may improve some people’s mental function, sleep quality, and cognition.

  • study revealed that Apoaequorin supplementation could significantly improve cognitive functioning in aging adults.
  • Another 2013 study in rats concluded that Apoaequorin is safe to use, and there were no side effects on the highest dose of 666.7 mg/kg BW/day.
  • Other human studies suggest that Apoaequorin is safe and doesn’t cause hepatotoxicity and other adverse effects.

Although it might be safe to use, there is no concrete evidence that this supplement increases intercellular calcium levels in the brain cells. Therefore it’s unclear how effective it is. So, more authentic research is needed to test this ingredient’s efficacy in brain function and sleep quality improvement.

Vitamin D (As Vitamin D3)

Another ingredient present in this brain booster is Vitamin D3, which your body naturally produces when exposed to sunlight. It helps regulate calcium and phosphorus absorption and ease the immune system’s normal functioning. In addition to average growth and development of bones and teeth, vitamin D also improves resistance to diseases like cancer or arthritis.

  • Vitamin D is a neuroprotective vitamin mainly used to regulate a healthy calcium level and promote strong immunity.
  • The lack of this vitamin can lead to depression, anxiety, dementia, and schizophrenia.
  • New research suggests that vitamin D supplements can help improve mood, reduce negative emotions, and reduce depression symptoms.

Why 7 Out of 10?

There are only two ingredients in this memory supplement. While one has not been fully proven yet to increase memory function, the other is a common ingredient found in almost any 2-3$ supplement on store shelves.

Company Claims (6 Out Of 10)

  • Claim#1: Clinically Tested Ingredients

⇒Our Thoughts

The manufacturers claim that Prevagen can improve memory, mental function, and sleep quality by using ingredients to enhance cognitive function in aging adults; a recent study also supports these claims.

Still, there are some lawsuits from the Federal Trade Commission and New York Attorney General for false advertising against Quincy Bioscience, alleging no evidence of improved memory or cognitive abilities. 

After these lawsuits, The FDA also took a stand against the false claims made by dietary supplements and announced that they would regulate these products.

  • Claim#2: Prevagen is Safe to Use

⇒Our Thoughts

Prevagen has been extensively researched and proven safe, with no toxic side effects. Although some studies suggest that taking more than the recommended dosage may not cause any harm, it’s best to stick within said quantity for optimal safety and effectiveness.

  • Claim#3: Prevagen is the No#1 Pharmacist Recommended Brand

⇒Our Thoughts 

Our research revealed that, despite making up a minority of all surveyed pharmacists, an overwhelming 72% still recommend this brand. This is especially impressive considering the stiff competition – Focus Factor and other brands were endorsed by only 13%. There must be something to this product; it looks like our instincts have been confirmed.

Why 6 Out of 10?

After facing litigation from the US Federal Trade Commission, this brand has come under scrutiny due to its potential buyers questioning their claims. While some studies have found positive effects after consuming it, other investigations conducted by independent groups showed no impact on the brain.

Prevagen Vs. Other Brands

  • Prevagen Vs. Neuriva

They are both nootropic supplements based on two ingredients, but in reality, they are different. The Prevagen uses a protein called Apoaequorin and vitamin D3, while the Neuriva formulated its nootropic around Phosphatidylserine and Coffee cherry.

The Prevagen is manufactured by Quincy bioscience, while Schiff Vitamins make Neuriva. The price of Neuriva original is 20$/30, and Neuriva plus is 87$/90. At the same time, Prevagen costs 39.95$ for regular strength and 50$ for extra strength.

These brands claim to improve learning abilities, make you smart, and improve your memory and concentration. You can check more differences between these two nootropics below.



Manufacturer: AmazonUs/RBHC7

Manufacturer: Quincy Bioscience

Coffee cherry,
Vitamin B6, B12, and
Folic acid.

Vitamin D (D3)

Daily Dose: 2 capsules per day

Daily Dose: 1 capsule per day

Customer Reviews

Customer Reviews

You can read more about these two brands in this article→ Prevagen Vs. Neuriva.

  • Prevagen vs. Focus factor

We have already discussed Prevagen, but if you look at the Focus factor, you will find that the Focus factor is formulated from a combination of many different nootropics, multivitamins, and herbal extracts.

Some ingredients used in the Focus factor are research-based and have some clinical history, while others don’t carry any nootropic value.

The usual recommended dose of Prevagen is one capsule per day, while you will need to take 4-8 pills of Focus factor to get your desired results.

You can read more about the difference between Prevagen Vs. Focus Factor in the table below.


Focus Factor

39.99$/30 servings


2 basic ingredients

A huge List of Ingredients

Quincy Bioscience

Focus Factor

1 Tablet per day

4 tablets per day

Read more about Prevagen Vs. Focus Factor ←Here

How does Prevagen work? (6 Out Of 10)

Our brain and memory are affected by an array of chemicals, like dopamine, serotonin, amyloid beta-protein, and calcium. Calmodulin, a protein in cells, might naturally help regulate calcium levels in the brain. Recent research has also highlighted Calmodulin as a potential agent for reducing age-related mental decline.

Apoaequorin, structurally similar to Calmodulin, is purported by Quincy bioscience to protect brain cells by binding to excess calcium within brain tissue. According to Anna, a neurologist, excess calcium in the nervous system is thought to contribute to brain cell damage. Abnormally elevated calcium levels in nervous tissue are often seen after brain injury from stroke or trauma, and it’s thought to be also seen with age-related cognitive decline. This is because as we age, our ability to regulate calcium in the body becomes increasingly impaired.

The maker of Prevagen claims that the active ingredient can protect brain cells by binding to excess calcium in the brain. There is also some in vitro evidence suggesting that Apoaequorin may be neuroprotective, and in vitro study in 2013 found that Apoaequorin may help prevent injury to hippocampal neurons that have been deprived of oxygen and oxygen deprivation is the main mechanism of brain damage in ischemic stroke.

Although these findings are encouraging and worth further exploration, there is currently no clinical evidence showing if or how well Apoaequorin can make its way through our digestive tract once ingested. Because when taking supplements, the effects may not be as potent or working altogether due to digestion changes in our bodies. After consumption, it must first pass through chemical modification and absorption into the bloodstream; if this process is interrupted, a supplement can become completely inactive by reaching its intended target within your cells and organs. Any supplements targeting brain functions must also cross something called a “Blood-Brain Barrier”; an extra layer of protection makes it difficult for molecules to reach our brains while still providing shielding from potentially damaging elements.

Experts and pharmacologists also agree that Apoaequorin is safe for oral use, as it slowly breaks down into amino acids. Unfortunately, taking it orally may not provide any neuroprotective benefits due to digestive enzymes breaking the large-size protein apart (22,885 daltons) before being able to cross through the blood-brain barrier (BBB). Therefore direct injection of Apoaequorin might be needed to experience its purported brain protection effects.

My Advice: Rather than splurging on expensive supplements for improved cognition, healthier lifestyle choices – like opting for organic food and exercising regularly – may make all the difference in reaching peak cognitive functioning. Simple adjustments to one’s daily routine could be even more beneficial than dietary supplements. You can do better than that and prevent your neurons from damaging by changing your lifestyle;

  • Reduce and limit your physiological stress.
  • Manage your blood sugar levels.
  • Do regular exercise and avoid social isolation.
  • Get the optimal sleep you need.

This does not mean that there are no nutritional supplements to protect your brain and improve your memory. Based on published studies, L-Tyrosine, Vitamin B6, Fish oil supplements, Folic Acid, Resveratrol, Caffeine, Phosphatidylserine, Acetyl-L-Carnitine, Ginkgo Biloba, and Bacopa monnieri, etc. can help you protect your brain and improve your memory at a basic level. All of these ingredients are packed in BrainPill®—That’s why we recommend it.

You can learn more about Apoaequorin ←Here.

Pros & Cons Of Prevagen Review

We Like;

  • It is one of the best-selling supplements in the nootropics space; The average rating is 4.2/5 stars based on over 9646 reviews on Amazon. This number can change with time.

  • There are many positive Prevagen reviews from customers, and most people who have already used it praised its efficacy. For most people, it works great and is worth the money.

  • The Prevagen pill is small and easy to swallow. You will need to take one capsule in the morning with or without food.

  • It is a third-party tested nootropic—a plus point in favor of this brand. Third-party testing means that an independent organization has reviewed the product and determined that the supplement is safe and effective.

  • It is safe because it contains no harmful or allergic ingredients. Also, a study proves that Apoaequorin is safe to use even in high doses.


Don't Like;

  • The stack is expensive compared to other competitors’ products—The average cost for regular strength 30 capsules is $43.99, while the extra strength is $61.63.

  • The active ingredient carries less scientific evidence than better-studied ingredients with proven track records.

  • There is a lawsuit against this company. The FTC claims that it made false advertising statements.

How to take it—Prevagen Dosage (10 Out Of 10)

The usual recommended dose of this stack is once daily, in the morning, with or without food. To stay safe and avoid potential adverse interactions, heed your doctor’s instructions – never exceed the suggested amount nor take it alongside any other medications or supplements.

  • Consult your healthcare provider if you are a pregnant or breastfeeding woman.
  • It is also recommended to avoid overdose because the excess of anything is harmful.

Is Prevagen safe—Prevagen Side effects? (9 Out Of 10)

The supplement is generally tolerated well and may not cause any side effects in certain people. When taken orally and as prescribed, the supplement is safe to use.  

Some studies have shown that taking 10 mg of Apoaequorin daily for 90 days is safe. However, this may only be the case for some people. Some people are also searching for Prevagen side effects – mayo clinic, but this product still needs to be covered by Mayo Clinic. 

Here is a list of expected side effects of the Prevagen supplement.

  • Headache
  • Nausea
  • Vomiting
  • Anxiety
  • Skin rashes
  • Insomnia (sleeping problems)
  • Cardiovascular problems like hypertension (High BP), irregular heart rate, and chest pain.
  • Some of the frequently reported Prevagen reviews’ side effects were neck pain and GI upset after using it for one month.
  • Some people also experienced dyslexia-type symptoms.

Avoid it if you are allergic to any of the Prevagen ingredients.

It is best to consult your doctor if you have any underlying medical conditions. Also, it is not clear if it can interact with other medications. Consult your doctor if you are already taking other medications and supplements.

Also, ask your doctor and pharmacist if you are a pregnant or breastfeeding woman because Apoaequorin might not be safe for your fetus or newborn baby.

To avoid potential side effects, take one Prevagen pill daily. Don’t exceed the recommended dosage. 

Note: This supplement has not been evaluated for its side effects through clinical research. So, this is not a complete list of Prevagen side effects. If you encounter any side effects other than the above, please consult your GP. 

Why 9 Out Of 10?

Even though the main ingredient used in this supplement is not fully known for memory enhancement, certain studies show that this supplement is safe to use and is not causing any serious side effects.

Does Prevagen work? (7 Out Of 10)

If you look at the clinical studies (although limited), product loyal customers, and Pharmacist recommendations, this product has something that gets so much appreciation.

The product has positive reviews. For example, this stack had 4.5/5 star ratings on Amazon when the total ratings were 7950. 

Please note that Amazon doesn’t allow an unverified reviewer to rate a product, so the above ratings are not manipulated. It may also change with time, so it’s better to regularly check the Amazon page for updated reviews. 

So, the customer Prevagen reviews are great, but the question is!!! Does Prevagen work, or Does Prevagen help memory?

If you’re experiencing age-related cognitive decline or memory loss, there is limited data to prove its efficacy. As with any diet or supplement, we recommend consulting your healthcare provider before using the product.

Looking at the positive Prevagen reviews, loyal customers, and limited research, you should give it a try. However, if you are looking for a full pledge Nootropic containing all the required ingredients, we recommend BrainPill.

Now that you have read our buyer’s guide and want to try this product, It’s completely OK and up to you, or you can use other high-quality alternatives such as BrainPill®.

Why 7 Out Of 10?

The mechanism needs to be clarified, but the customers praise it. Experts say that Apoaequorin degrades before reaching the brain and thus cannot affect your mental performance.

Is Prevagen FDA approved?

Despite the popularity of nootropics, there is not enough evidence to support their claims. According to Harvard health publishing, there are currently no FDA-approved memory supplements on the market. In other words, FDA doesn’t regulate supplements.

According to a new survey, about 25% of adults use some form of natural nootropic to improve brain power, but no concrete evidence supports their claims. 

Where to Buy Prevagen?

This product is available on all online retailers like Amazon, Walmart, Walgreens, CVS, and many others, but the best place is the company website and Amazon.

  • The Prevagen cost on Amazon for Regular Strength 30 Capsules—is $40.65, and for Prevagen Extra Strength 30 capsules—it is $59.95. 
  • Costco Prevagen— not available.
  • Prevagen Walmart — $39 for a regular strength containing 30 capsules. $59.88 for extra strength.
  • Prevagen Walgreens —$39.99.
  • Prevagen CVS: $60.49 for extra strength.

What Do Other People Think About It—Customer Prevagen Reviews? (8 Out Of 10)

The customer reviews are mixed, but the majority praised the efficacy of this nootropic. 

Many different sellers sell the product, but the average global rating for extra strength on Amazon was 4.4/5 stars when the total reviews were 3,651. While the regular strength Prevagen also has 6,920 global ratings, surprisingly, this one also has a 4.3/5 star rating. There are no Prevagen reviews at the mayo clinic because they don’t have any related product page on their website. Here is a look at the Amazon ratings and reviews;

  • Ratings on Amazon: 4.4/5 (Total reviews 3,651).
  • Ratings on CVS: 4.3/5 (Total reviews 157)
  • Ratings on Walmart: 4/5 (Total reviews 468)

(Note: These numbers can change with time, so it’s better to visit Amazon product pages more often to know its updated rating).

Let’s look at some of the positive and negative reviews of Prevagen.

Positive Prevagen Reviews

  • For some people, it’s a great product that works as advertised. They think it will help you with quicker memory recall.


Prevagen Reviews
Prevagen Reviews
  • W. B. Phillips on Amazon thinks he is still determining whether it will work, but the price and seller were great. 
  • According to a customer on Amazon that this product works but is expensive. 
  • Another 40-year-old verified purchaser on Amazon says that Prevagen has helped her improve her recall of things, plus it also helped her sleep quality.
Prevagen Review, Prevagen Reviews
Prevagen Reviews

Negative Prevagen Reviews

  • One negative review was about the product’s side effects. The reviewer mentions that he was experiencing incapacitating dizziness after taking this for three days.
  • David Zahn is another verified purchaser of this product, and he also thinks that this product is a scam and a placebo—Don’t work at all. 
  • This product is super expensive for many customers and is increasing in price monthly.
  • John Hyatt reported that the price was $74 a month ago, and it’s $112 now. 

Prevagen Review, Prevagen Reviews

There are other positive and negative testimonials on Amazon and Walmart.

What do we think about this product?

Aside from all the negative aspects, this product has received impressive positive reviews and consumer testimonials. 

We could not find any specific complaints regarding company policies, which is a strong point for this product. Only buyers who don’t like the product or consider it profitable can return it without asking questions.

Is Prevagen a scam?

This is not a scam, but the brand needs more solid research to prove its efficacy. This brain-boosting supplement may offer some or all of the shared benefits. But due to the relatively expensive price tag and the FTC lawsuit, it is difficult for many potential buyers to try the formula.

Does Prevagen really help memory?

This might work for some people, but as a pharmacist, I recommend using a supplement with tested ingredients like Citicoline, Bacopa monnieri, phosphatidylserine, vitamin B complex, N-Acetyl L-Tyrosine, L-theanine, and many such already proven ingredients. 

“The main ingredient in Prevagen, apoaequorin, hasn’t been studied enough and needs more research.” Many customers are pleased with its effectiveness on Amazon and other platforms.

Do pharmacists recommend Prevagen?

According to a Pharmacy Times Magazine survey, most pharmacists recommend this brand, but many believe it’s a total lie.

Being a pharmacist, I don’t think more than 70% of all pharmacists will recommend it because the product is based on only one ingredient that is still not thoroughly researched. So, the truth about Prevagen is that it is based on one unknown component and one very common vitamin. 

I recommend all those products or supplements with clinically tested, proven, and safe ingredients.

Prevagen Alternatives—Comparison

It is a unique and new nootropic, and no other product contains Apoaequorin. However, some nootropics in the market contain high-quality and premium brain-boosting ingredients. Some of the products are

If you compare it with BrainPill, you will see a vast difference in their formulations. The BrainPill uses many ingredients, some of which are well-researched for improving brain performance, while Prevagen has limited research behind its main ingredient.

Neuriva is also based on 2-3 ingredients, but their primary nutrient (Phosphatidylserine) is well-researched and has proven efficacy in brain-boosting.

The Focus Factor has a massive list of many different nutrients, vitamins, and minerals. According to the company, this product will improve your memory and focus.

What Sets Prevagen apart from its competitors?

When looking for a health supplement to improve your brain functioning, Prevagen stands out from its competitors in a few distinct ways. Firstly, its unique and patented formula may offer superior results to other brands. Secondly, it has garnered over 17000 positive reviews from customers. What sets it apart even further is its 45-day money-back guarantee for all Prevagen branded products, which promises that unsatisfied people can get their money back without hassle.

Is there any room for improvement?

This product could become even more effective with the addition of top-notch ingredients. Proven vitamins like B6 and B12 can provide excellent nerve support, while herbal extracts such as Ginkgo Biloba, Bacopa monnieri, Phosphatidylserine, Panax ginseng, and Rhodiola Rosea can upgrade its quality further.

Verdict—Prevagen Review

This nootropic’s unique ingredient is believed to significantly improve short-term memory. It also helps improve concentration, focus, and thinking skills. 

The customer Prevagen reviews are great, and the regular strength had got 4.3/5 star ratings when the total reviews on Amazon were more than 5500.  

So—If you are looking for a memory booster, this may help you improve your memory and concentration. But please remember that no solid evidence exists to hold up its claims.

Overall, the product has one unproven ingredient but thousands of outstanding verified customer reviews, making it worth trying.

This stack will work for some people, but it doesn’t provide 100% guaranteed results. This is my view, and I’m not calling it a useless product.

Why is Our #1 Recommended Brain Supplements Brain Pill?

If you don’t want to buy the above products and are looking for other high-quality brain supplements, We recommend that you try Brain Pill®


Because !!! Brain Pill uses a blend of high-quality ingredients and puts equal weight on long-term brain health.

Although the formula is expensive, it improves focus and brain function, reduces stress and anxiety, and increases memory recall and brain cell protection.

And most importantly, they offer you a 67-day money-back guarantee—if you are not satisfied with the results, return them and get your money back. 


Brain Pill

Vitamin D3

Huperzia Serrata,
Gingko Biloba,
Vitamin B6,
Folic Acid,
Vitamin B12, L-
Pantothenic acid.

Price: 100$/60 capsules for extra strength.

Price: 69$/60 capsules

Manufactured by Quincy Bioscience

Manufactured by Leading Health Edge

This article is written by a Registered Pharmacist Manzoor Ahmad (Pharm.D) and medically reviewed by Sajid (Ph.D. in Pharmacognosy).

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Prevagen is an over the counter cognitive enhancement supplement that claims to support a healthy brain, sharpen the mind, and improve memory, focus, and attention. However, there is no concrete evidence to support these claims.

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