Prevagen Review: Complaints, Ingredients, Side Effects [2021 Expert Reviews]

In this “Prevagen Review,” you will learn,

  • What is Prevagen, and how it works?
  • Does Prevagen Work?
  • What are it’s ingredients?
  • Is it safe to use—Prevagen Side Effects?
  • What are the Pros & Cons of this supplement?
  • What do other people think about this product (customer Prevagen reviews)?
  • What do we think about this product?.

Prevagen is a dietary brain boosting supplement manufactured by Quincy Bioscience— a US biotechnology company based in Madison, Wisconsin.

It is claimed to be the top-selling memory improving supplement on the market.

According to the company, the supplement will improve your memory, sharpen your mind, support clearer thinking, and aid with mild memory problems associated with aging.

Please note that the company is not accredited by the Better Business Bureau (BBB), and there are no complaints from the customers. However, The BBB rating of Quincy Bioscience is A+.

Prevagen comes in 2 variants. One is prevagen regular strength that contains 10 mg of Apoaequorin, and the other is Prevagen extra strength which contains 20 mg of Apoaequorin.

  • Prevagen extra strength 60 capsules
  • Prevagen regular strength 60 capsules

The price of Prevagen regular strength is 39.95$ and 50$ for extra strength.

This means that it is quite expensive, but is it worth the price or a scam like many other brands?

Lets have a quick overview first.

Read our #1 Recommended Natural nootropic → BrainPill® Review.

Prevagen Review (Quick)

81NDsZQB4aL. AC SL1500 1

Full Name: Prevagen Improves Memory

Company Name: Quincy Bioscience

Where to buy Prevagen: Amazon

Amazon Rating: 4.5/5 (5027)

(May change with time)

Our Rating: 7 out of 10

Prevagen Review (Full)

Our research team gave us all the information they found about the formula’s proprietary Prevagen ingredients, side effects, benefits, studies related to the Apoaeaquorin and Vitamin D, where to buy Prevagen, and more. 

Let’s dive deep into Prevagen Review.

What is Prevagen?

It is a dietary brain boosting supplement made from 2 active ingredients. The core ingredients are Apoaequorin & Vitamin D (as D3 cholecalciferol).

The company claim that Prevagen is used to help with mild memory loss associated with aging. It is also used to support brain function as it contains Apoaequorin and Vitamin D.

According to the label, the supplement is capable of delivering the following benefits.

  • It supports healthy brain function.
  • It reduces your brain fog and clear thinking,
  • It sharpen your mind.

Note that this review of Prevagen is based on our honest opinions and hours of research on this product. We will tell you whether it’s worth the money or a waste.

You can also read our #1 Recommended Brain Booster Product —BrainPill Review.

Prevagen ingredients (7 Out Of 10)

There are only two active constituents in the Prevagen Ingredients list.


The first Prevagen Ingredient is Apoaequorin, which is a calcium-binding protein obtained from jellyfish. Some people use it to improve memory, mental function, and sleep quality, but there is insufficient evidence to rate this protein’s effectiveness in the above conditions.

Preliminary research suggests that taking 10 mg Apoaequorin daily for 90 days may improve mental function, sleep, forgetfulness, recall, and in some people, the need for reminders.

A 2013 study in rats concluded that Apoaequorin is safe to use, and there were no side effects on the highest dose of 666.7 mg/kg BW/day.

Another human Study suggests that Apoaequorin is safe to use and doesn’t cause hepatotoxicity and other adverse effects.

However, more authentic research is needed to test this ingredient’s efficacy in brain function and sleep quality improvement.

Vitamin D (As Vitamin D3)

Another ingredient present in this brain booster is Vitamin D3. It is a fat-soluble vitamin that your body is naturally producing when your body is exposed to sunlight.

Vitamin D’s most important functions are to regulate the absorption of calcium and phosphorus and ease the immune system’s normal functioning. In addition to the average growth and development of bones and teeth, sufficient vitamin D is necessary to improve resistance to some diseases.

Why 7 Out of 10?

This supplement contains only two ingredients, and the one is still not fully proven to be effective in memory enhancement. While the other one is a very common ingredient that can be found in any 2-3$ dietary supplement.

Company Claims (6 Out Of 10)

Claim#1: Clinically Tested Ingredients

⇒Our Thoughts

  • The manufacturer claims that the above mentioned ingredients can improve memory, mental function, and sleep quality. A recent study supports the claim that It can be used to enhanced cognitive function in aging adults. Another study that Quincy BioScience sponsored claims the improvements in executive functioning and delayed recall.
  • However, the Federal Trade Commission (FTC) and New York Attorney General have filed a lawsuit against the manufacturers of Prevagen, claiming that there is no evidence that the pill improves memory or prevents memory loss.
  • After this, the FDA took a stand against false claims and announced a plan to regulate and oversee dietary supplements.

Claim#2: Prevagen is Safe to Use

⇒Our Thoughts

  • Yes, if you look at the ingredients, they both are safe to use and don’t cause any toxicity. Don’t use more than the recommended dose. 

Claim#3: Prevagen is the No#1 Pharmacist Recommended Brand

⇒Our Thoughts 

  • While researching the brand, our research team thoroughly checked all the facts and figures about Prevagen. According to the 2019 “Pharmacy Times” survey, 72% of pharmacists recommend Prevagen, while 13% recommend Focus Factor and other brands. In my opinion, not all pharmacist think the same way, so it might be a marketing tactic. 

Why 6 Out of 10?

They claim that this supplement is clinically tested. Although some studies back these claims, there is a lawsuit against this company from the US Federal Trade Commission. They were not satisfied with the benefits of the supplement.

How Prevagen works? (6 Out Of 10)

Various chemicals affect the human brain and memory. Some of the essential chemicals are acetylcholine, norepinephrine, calcium, amyloid, and glutamate, etc.

It is believed that Calmodulin—a protein present in the cells might help regulate calcium in the brain and reduce memory loss and age-related mental decline.

Apoaequorin is structurally similar to human calcium-binding protein (Calmodulin). As they both are structurally identical, experts think that Apoaequorin can also help you improve your mental performance and increase focus and cognitive abilities.

The Apoaequorin also binds to calcium in the laboratory experiment and lowers the calcium level. Therefore, researchers hope that it can regulate calcium to reduce mental retardation.

However, According to some experts and pharmacologists, after oral administration, this protein is degraded into amino acids by the stomach enzyme (Pepsin) and is not possible to reach the brain. That’s the reason it relatively safe to use, but at the same, the conversion of this protein into amino acid makes it inactive.

Also, Even If it survives the digestive enzymes still, the Apoaequorin can’t cross the blood-brain barrier (BBB) because the size of this protein is 22,885 daltons and to cross the BBB one of the requirements a molecule must be smaller than 400 daltons.

So how do we know that Prevagen is neuroprotective when it can’t get into the brain? The only possibility is to inject Apoaequorin into the brain directly with a needle—which is almost impossible.

My Advice: Although you can’t shield your neuron with this protein, you can do better than that and prevent your neuron from damaging by changing your lifestyle like;

  • Reduce and limit your physiological stress.
  • Manage your blood sugar levels.
  • Do regular exercise and avoid social isolation.
  • Get optimal sleep you need.

This does not mean that there are no nutritional supplements that can protect your brain and improve your memory. Based on published studies, L-Tyrosine, Vitamin B6, Fish oil supplements, Folic Acid, Resveratrol, Caffeine, Phosphatidylserine,  Acetyl-L-Carnitine, Ginkgo Biloba, and Bacopa monnieri etc can help you protect your brain and improve your memory at a basic level.

You can learn more about Apoaequorin ←Here

Pros & Cons Of Prevagen Review


  • Prevagen is one of the best-selling supplements in the nootropics space.
  • There is a good number of positive Prevagen reviews from customers.
  • The pill is easy to swallow.
  • The product is a third-party tested supplement.
  • It is safe to use, as it contains no harmful ingredients.



  • The product is expensive compare to other competitors’ products.
  • The active ingredient carries less scientific evidence compared to better-studied ingredients with proven track records.
  • FTC claims that they made false advertising statements.

Prevagen Dose (10 Out Of 10)

The usual recommended dose of Prevagen is once daily, in the morning, with or without food. Don’t exceed the suggested amount, and follow your healthcare provider’s instructions.

Don’t take Prevagen with other prescription drugs and supplements as it may interact and cause undesirable effects.

Consult your health care provider if you are a pregnant or breastfeeding woman.

It is also recommended to avoid overdose because the excess of anything is harmful.

Is Prevagen safe—Prevagen Side effects? (9 Out Of 10)

The supplement is generally tolerated well and may not cause any side effects in certain people. When taken orally and as prescribed the supplement is safe to use. 

Some studies have shown that taking 10 mg of Apoaequorin daily for 90 days is possibly safe. However, this may not be the case for all people.

Here is a list of expected side effects of the Prevagen supplement.

  • Headache
  • Nausea
  • Vomiting
  • Anxiety
  • Skin rashes
  • Insomnia (sleeping problems)
  • Cardiovascular problems like hypertension (High BP), irregular heart rate, and chest pain.

Avoid it if you are allergic to any of the Prevagen ingredients.

It is best to consult your doctor if you have any underlying medical condition. Also, it is not clear if it can interact with other medications. Consult your doctor if you are already taking other medications and supplements.

To avoid any potential side effects, you need to take the recommended dose: one pill per day.

Note: This supplement has not been evaluated for its side effects through clinical research. So, this is not a complete list of Prevagen side effects. If you encounter any side effects other than the above please consult your GP. 

Why 9 Out Of 10?

Even though the main ingredient used in this supplement is not fully known for memory enhancement, certain studies show that this supplement is safe to use and is not causing any serious side effects.

Does Prevagen work? (7 Out Of 10)

If you look at the clinical studies (although limited), product loyal customers, and Pharmacist recommendations, this product has something that gets so much appreciation.

The product has pretty much positive reviews. Prevagen had 4.5/5 star ratings on Amazon when the total ratings were 4354.

Please note that Amazon doesn’t allow an unverified reviewer to rate a product, so the above ratings are not manipulated. It may also change with time, so it’s better to check the Amazon page for updated reviews. 

The reviews are great, but the question is… Does Prevagen work, or Does Prevagen really help memory?

If you’re experiencing age-related cognitive decline or memory loss, we think there is limited data to prove Pravegan efficacy. As with any diet or supplement, we recommend consulting your healthcare provider before using the product.

Looking at the positive Prevagen reviews, loyal customers, and limited research, we think you should give it a try. If you are looking for a full pledge Nootropic containing all the required ingredients, we recommend BrainPill.

Now that you have read our Prevagen review and want to try this product, It’s completely OK and up to you, or you can use other high-quality alternatives such as BrainPill®.

Why 7 Out Of 10?

Most of the customers were praising this supplement, but there is confusion in the mechanism of this ingredient. Many experts think that Apoaequorin destroys before it reaches the brain, and when it can’t reach the brain, how can it affect your mental performance?

Where to Buy Prevagen?

This product is available on all online retailers like Amazon, Walmart, Walgreens, CVS, and many others, but the best place is the company website and Amazon.

The prices on Amazon are;

  • Prevagen Regular Strength 30 Capsules—$40.65
  • Prevagen Extra Strength 30 capsules—$59.95

Customer Prevagen Reviews (8 Out Of 10)

The customer reviews are mixed, but the majority praised the efficacy of this product.

Let’s take a look at some of the positive and negative Prevagen reviews.

  • For some people, it’s a great product, and it works as advertised. They think it will help you with quicker memory recall.

Prevagen Review

  • According to a customer on Amazon that this product works but is expensive.

Prevagen Review

  • One negative Prevagen review was about the product side effects. The reviewer mentions that he was experiencing incapacitating dizziness after taking this for three days.

Prevagen Review

There are other positive and negative Prevagen reviews on Amazon.

What do we think about this product?

Aside from all the negative aspects, this product has received impressive positive reviews and testimonials from real consumers. 

We could not find any specific complaints regarding company policies, which is a strong point in favor of this product. Any buyer who does not like the product or does not consider it profitable can return it without asking questions.

Is Prevagen a scam?

In my opinion, this is not a scam. This brain-boosting supplement may offer some or all of the shared benefits. But due to the relatively expensive price tag and the FTC lawsuit, it is difficult for many potential buyers to try the formula.

Does Prevagen really help memory?

As a pharmacist, I recommend using a supplement that contains already tested ingredients like Citicoline, Bacopa monnieri, phosphatidylserine, vitamin B complex, N-Acetyl L-Tyrosine, L-theanine, and many such already proven ingredients. 

This doesn’t mean that Prevagen will not work, but the fact is that its main ingredient is still not very well studied and need more research.

Do pharmacists recommend Prevagen?

According to a Pharmacy Times Magazine survey, most pharmacists recommend this brand, but many believe it’s a total lie.

Prevagen Alternatives

Prevagen is a unique nootropic, and there is no other product that contains Apoaequorin. However, some nootropics in the market contain high-quality and premium brain-boosting ingredients. Some of the products are

Verdict—Prevagen Review

To wind up our Prevagen Review, There are different factors to consider before buying a supplement.

If you are looking for a memory booster, this may be the answer for you. Prevagen is a supplement that uses a proprietary ingredient called Apoaequorin.

This unique ingredient is believed to improve short-term memory significantly. It can also help improve concentration, focus, and thinking skills.

This is my personal opinion, and I’m not claiming that this product will work like a Miracle.

After reading our “Prevagen Review” and still want to buy this product, it’s totally up to you. But our #1 recommendation will always be Brain Pill®.

Our #1 Recommended Brain Supplements is Brain Pill.

If you don’t want to buy the above products and look for other high-quality brain supplements, We recommend that you try Brain Pill®


Because…Brain Pill uses high-quality ingredients, plus they put equal weight on long-term brain health.

Although the formula is expensive, it will improve your focus and brain function, reduce stress and anxiety, will increase memory recall and brain cell protection.


Brain Pill

81NDsZQB4aL. AC SL1500
product shadow

Vitamin D3

Huperzia Serrata,
Gingko Biloba,
Vitamin B6,
Folic Acid,
Vitamin B12, L-
Pantothenic acid.

Price: 100$/60 capsules for extra strength.

Price: 69$/60 capsules

Manufactured by Quincy Bioscience

Manufactured by Leading Health Edge

This article is written and reviewed by a Registered Pharmacist Manzoor Ahmad (Pharm.D)

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