Prevagen Review—Does It Work? [2021 Pharmacist Reviews]

In this “Prevagen Review,” you will learn,

  • What is Prevagen, and how it works?
  • Does Prevagen really work?
  • What are the ingredients?
  • Is it safe to use—Prevagen Side Effects?
  • What are the pros & cons of this supplement?
  • What do other people think it—customer Prevagen reviews?
  • What do we think about this product?

Intelligent and super focused like a genius?

Do you want to get good exam scores, be attractive in your presentation and remember names and places?

You likely have heard about Prevagen— a novel over-the-counter dietary brain-boosting supplement manufactured and marketed by Quincy Bioscience— a US biotechnology company based in Madison, Wisconsin.

It is claimed to be the top-selling memory-improving supplement on the market.

According to the company, the supplement will improve your memory, sharpen your mind, support clearer thinking, and aid with mild memory problems associated with aging.

Please note that the company is not accredited by the Better Business Bureau (BBB), and there are no complaints from the customers. However, the BBB rating of Quincy Bioscience is A+.

Prevagen comes in 2 variants. One is regular strength that contains 10 mg of Apoaequorin, and the other is extra strength which contains 20 mg of Apoaequorin.

  • Prevagen extra strength 60 capsules
  • Prevagen regular strength 60 capsules

The price of Prevagen regular strength is 39.95$ and 50$ for extra strength. So— it is pretty expensive, but is it worth the price or a scam like many other brands?

In this Prevagen Review, we will tell you the science behind each ingredient, its use in brain-boosting, what makes it unique from its competitors, and at the end of the review, I will be giving my opinion if it’s worth your hard-earned money or not?

Why should you trust us?

Because being a pharmacist, I have to educate you about each ingredient present in these nootropics.

Our team of pharmacists and Ph.D. scholars gather all the relevant information about the product and thoroughly check them with the trusted sources available on the internet.

We also add verified customer reviews from Amazon and other platforms to determine what other people think about the product.

At the bottom of every article, we add our honest and unbiased opinion free from marketing gimmicks. Our product reviews are mainly based on adherence to quality, clinical studies, and the time spent with the products.

We only recommend products and supplements that are high quality, affordable, safe to use, and can positively impact your life.

Read our #1 Recommended Natural nootropic → BrainPill® Review.

Let’s have a quick overview first.

Prevagen Review (Quick)

Full Name: Prevagen Improves Memory

Company Name: Quincy Bioscience

Where to buy Prevagen: Amazon

Amazon Rating: 4.5/5 (5027)

(May change with time)

Our Rating: 7 out of 10

Prevagen Review (Full)

Our research team gave us all the information they found about the formula’s proprietary Prevagen ingredients, its side effects, benefits, studies related to the Apoaeaquorin and Vitamin D, where to buy Prevagen, and more. 

Let’s dive deep into this Prevagen Review.

What is Prevagen?

Prevagen is a dietary brain-boosting supplement made from a combination of 2 active ingredients. The core ingredients are Apoaequorin & Vitamin D (as D3 cholecalciferol).

The company claim that the product is used to help with mild memory loss associated with aging and improve memory. It is also used to support healthy brain function as it contains Apoaequorin and Vitamin D.

According to the label, the supplement is capable of delivering the following benefits.

  • It supports healthy brain function.
  • It reduces your brain fog and clear thinking,
  • It sharpens your mind.

Note that this review of Prevagen is based on our honest opinions and hours of research on this product. We will tell you whether it’s worth the money or a waste.

Prevagen ingredients (7 Out Of 10)

There are only two active constituents in the Prevagen Ingredients list.

  • Apoaequorin

The key ingredient is a calcium-binding protein obtained from jellyfish, which could be beneficial for those who struggle with forgetfulness or recall issues. In addition, preliminary research has shown that taking 10 mg of Apoaequorin per day may improve some people’s mental function, sleep quality, and cognition.

A 2013 study in rats concluded that Apoaequorin is safe to use, and there were no side effects on the highest dose of 666.7 mg/kg BW/day.

Another human Study suggests that Apoaequorin is safe to use and doesn’t cause hepatotoxicity and other adverse effects.

However, more authentic research is needed to test this ingredient’s efficacy in brain function and sleep quality improvement.

  • Vitamin D (As Vitamin D3)

Another ingredient present in this brain booster is Vitamin D3, which your body naturally produces when exposed to sunlight. It helps regulate calcium and phosphorus absorption as well as ease the immune system’s normal functioning. In addition to average growth and development of bones and teeth, vitamin D also improves resistance from diseases like cancer or arthritis.”

Why 7 Out of 10?

There are only two ingredients in memory supplements. While one has not been fully proven yet to increase memory function, the other is a common ingredient that can be found in almost any 2-3$ supplement on store shelves.

Company Claims (6 Out Of 10)

Claim#1: Clinically Tested Ingredients

⇒Our Thoughts

While the manufacturers claim that Prevagen can improve memory, mental function, and sleep quality by using ingredients to enhance aging adults’ cognitive function, a recent study also supports these claims.

Still, there are lawsuits from the Federal Trade Commision and New York Attorney General for false advertising against Quincy BioScience, alleging no evidence of improved memory or preventing loss of memories.

After these lawsuits, The FDA took a stand against the false claims made by dietary supplements and announced that they would regulate these products.

Claim#2: Prevagen is Safe to Use

⇒Our Thoughts

Yes, if you look at the ingredients, they both are safe to use and don’t cause any toxicity. Some studies also support its safety and think it is safe even if taken more than the dose present in Prevagen. It’s recommended not to use more than the recommended dose. 

Claim#3: Prevagen is the No#1 Pharmacist Recommended Brand

⇒Our Thoughts 

My research team checked all the facts and figures about this brand. According to the 2019 “Pharmacy Times” survey, 72% of pharmacists recommend Prevagen while only 13% recommended Focus Factor or other brands. In my opinion not all pharmacists think alike; it might just be a marketing tactic.

Why 6 Out of 10?

They claim to have clinically tested this supplement, but there is a lawsuit against them from the US Federal Trade Commission. The company has had some studies back their claims and others that do not show benefits of taking it at all.

Prevagen Vs Other Brands

Prevagen Vs Neuriva

They both are based on two ingredients, but both of them are different. The Prevagen uses a protein called Apoaequorin and vitamin D3, while the Neuriva formulated its nootropic around Phosphatidylserine and Coffee cherry.

The Prevagen is manufactured by Quincy bioscience, while Schiff Vitamins make Neuriva. The price of Neuriva original is 20$/30 counts, and Neuriva plus is 87$/90 counts. At the same time, the cost of Prevagen is 39.95$ for regular strength and 50$ for extra strength.

These brands claim to improve learning abilities, make you smart, improve your memory and concentration. You can check more differences between these two nootropics below.



Manufacturer: AmazonUs/RBHC7

Manufacturer: Quincy Bioscience

Coffee cherry,
Vitamin B6, B12, and
Folic acid.

Vitamin D (D3)

Daily Dose: 2 capsules per day

Daily Dose: 1 capsule per day

Customer Reviews

Customer Reviews

You can read more about these 2 brands in this article→ Prevagen Vs Neuriva

Prevagen vs Focus factor

We have already discussed Prevagen, but if you look at the Focus factor, you will find that the Focus factor is formulated from a combination of many different nootropics, multivitamins, and herbals extracts.

Some of the ingredients used in the Focus factor are research-based and have some clinical history behind them, while others don’t carry any nootropic value.

You can read more about the difference between Prevagen Vs. Focus Factor in the table below.


Focus Factor

39.99$/30 servings


2 basic ingredients

A huge List of Ingredients

Quincy Bioscience

Focus Factor

1 Tablet per day

4 tablets per day

Read more about Prevagen Vs Focus Factor ←Here

How Prevagen works? (6 Out Of 10)

There are various chemicals that affect the human brain and memory. Some of these chemicals include acetylcholine, norepinephrine, calcium, amyloid beta-protein etc.

Experts think that Calmodulin, a protein present in cells might help regulate calcium levels in the brain to reduce age related mental decline like loss of focus or cognitive abilities as well as improve memory function .

Apoaequorin has been touted for its benefits due to being structurally similar with Calmodulin because they both have identical structures where it can also be beneficial towards improving your mental performance by increasing focus and having better cognitive skills among others.

The Apoaequorin also binds to calcium in the lab and can lower its levels. Researchers hope that this protein will help regulate calcium, which may reduce mental retardation by protecting neurons from damage due to high-calcium environments.

However, according some experts and pharmacologists, while it is safe for oral use because of how slowly it breaks down through hydrolysis into amino acids; you cannot get enough Apoaequorin into the brain after ingesting orally without having side effects or adverse reactions. Since most digestive enzymes break proteins apart.

Therefore, we can only conclude that Apoaequorin is probably neuroprotective when it’s injected directly into the brain. However, this becomes almost impossible to do because of its large size (22,885 daltons) and inability to cross the blood-brain barrier (BBB).

My Advice: Although you can’t shield your neuron with this protein, you can do better than that and prevent your neuron from damaging by changing your lifestyle like;

  • Reduce and limit your physiological stress.
  • Manage your blood sugar levels.
  • Do regular exercise and avoid social isolation.
  • Get the optimal sleep you need.

This does not mean that there are no nutritional supplements to protect your brain and improve your memory. Based on published studies, L-Tyrosine, Vitamin B6, Fish oil supplements, Folic Acid, Resveratrol, Caffeine, Phosphatidylserine, Acetyl-L-Carnitine, Ginkgo Biloba, and Bacopa monnieri, etc. can help you protect your brain and improve your memory at a basic level. All of these ingredients are packed in BrainPill®—That’s why we recommend it.

You can learn more about Apoaequorin ←Here

Pros & Cons Of Prevagen Review

What Do We Like About It?

  • It is one of the best-selling supplements in the nootropics space.

  • There is a good number of positive Prevagen reviews from customers.

  • The pill is small and easy to swallow.

  • The is a third-party tested nootropic—which is a plus point in favor of this brand.

  • It is safe to use, as it contains no harmful ingredients.


What Don't We Like About It?

  • The stack is expensive compare to other competitors’ products.

  • The active ingredient carries less scientific evidence compared to better-studied ingredients with proven track records.

  • There is a lawsuit against this company. The FTC claims that they made false advertising statements.

How to take it—Prevagen Dosage (10 Out Of 10)

The usual recommended dose of this stack is once daily, in the morning, with or without food. Don’t exceed the suggested amount, and follow your healthcare provider’s instructions.

Alos, please don’t take it with other prescription drugs and supplements as it may interact and cause undesirable effects.

  • Consult your health care provider if you are a pregnant or breastfeeding woman.
  • It is also recommended to avoid overdose because the excess of anything is harmful.

Is Prevagen safe—Prevagen Side effects? (9 Out Of 10)

The supplement is generally tolerated well and may not cause any side effects in certain people. When taken orally and as prescribed, the supplement is safe to use.  

Some studies have shown that taking 10 mg of Apoaequorin daily for 90 days is possibly safe. However, this may not be the case for all people. 

Here is a list of expected side effects of the Prevagen supplement.

  • Headache
  • Nausea
  • Vomiting
  • Anxiety
  • Skin rashes
  • Insomnia (sleeping problems)
  • Cardiovascular problems like hypertension (High BP), irregular heart rate, and chest pain.

Avoid it if you are allergic to any of the Prevagen ingredients.

It is best to consult your doctor if you have any underlying medical conditions. Also, it is not clear if it can interact with other medications. Consult your doctor if you are already taking other medications and supplements.

To avoid any potential side effects, you need to take the recommended dose: one pill per day.

Note: This supplement has not been evaluated for its side effects through clinical research. So, this is not a complete list of Prevagen side effects. If you encounter any side effects other than the above, please consult your GP. 

Why 9 Out Of 10?

Even though the main ingredient used in this supplement is not fully known for memory enhancement, certain studies show that this supplement is safe to use and is not causing any serious side effects.

Does Prevagen work? (7 Out Of 10)

If you look at the clinical studies (although limited), product loyal customers, and Pharmacist recommendations, this product has something that gets so much appreciation.

The product has pretty much positive reviews. This stack had 4.5/5 star ratings on Amazon when the total ratings were 6154. 

Please note that Amazon doesn’t allow an unverified reviewer to rate a product, so the above ratings are not manipulated. It may also change with time, so it’s better to regularly check the Amazon page for updated reviews. 

So, the customer Prevagen reviews are great, but the question is… !!! Does Prevagen work, or Does Prevagen really help memory?

The answer is….!!!

If you’re experiencing age-related cognitive decline or memory loss, we think there is limited data to prove its efficacy. As with any diet or supplement, we recommend consulting your healthcare provider before using the product.

Looking at the positive Prevagen reviews, loyal customers, and limited research, we think you should give it a try. If you are looking for a full pledge Nootropic containing all the required ingredients, we recommend BrainPill.

Now that you have read our Prevagen review and want to try this product, It’s completely OK and up to you, or you can use other high-quality alternatives such as BrainPill®.

Why 7 Out Of 10?

The mechanism is confusing, but the customers are praising it. Experts say that apoaequorin degrades before reaching the brain and thus cannot affect your mental performance.

Is Prevagen FDA approved?

Despite the popularity of nootropics, there is not enough evidence to support their claims. According to Harvard health publishing, there are currently no FDA-approved memory supplements on the market. In other words, FDA doesn’t regulate supplements.

According to a new survey, about 25% of adults use some form of natural nootropic to improve brain power, but there is no concrete evidence to support their claims. 

Where to Buy Prevagen?

This product is available on all online retailers like Amazon, Walmart, Walgreens, CVS, and many others, but the best place is the company website and Amazon.

The prices on Amazon are;

  • Prevagen Regular Strength 30 Capsules—$40.65
  • Prevagen Extra Strength 30 capsules—$59.95

Customer Prevagen Reviews (8 Out Of 10)

The customer reviews are mixed, but the majority praised the efficacy of this product.

Let’s take a look at some of the positive and negative Prevagen reviews.

  • For some people, it’s a great product, and it works as advertised. They think it will help you with quicker memory recall.
Prevagen Review
Amazon Prevagen Reviews
  • According to a customer on Amazon that this product works but is expensive.
Prevagen Review
Amazon Prevagen Reviews
  • One negative Prevagen review was about the product side effects. The reviewer mentions that he was experiencing incapacitating dizziness after taking this for three days.
Prevagen Review
Amazon Prevagen Reviews

There are other positive and negative Prevagen reviews on Amazon.

What do we think about this product?

Aside from all the negative aspects, this product has received impressive positive reviews and testimonials from real consumers. 

We could not find any specific complaints regarding company policies, which is a strong point in favor of this product. Any buyer who does not like the product or does not consider it profitable can return it without asking questions.

Is Prevagen a scam?

In my opinion, this is not a scam. This brain-boosting supplement may offer some or all of the shared benefits. But due to the relatively expensive price tag and the FTC lawsuit, it is difficult for many potential buyers to try the formula.

Does Prevagen really help memory?

This might work for some people, but as a pharmacist, I recommend using a supplement that contains already tested ingredients like Citicoline, Bacopa monnieri, phosphatidylserine, vitamin B complex, N-Acetyl L-Tyrosine, L-theanine, and many such already proven ingredients. 

“The main ingredient in Prevagen, apoaequorin, hasn’t been studied enough and needs more research.”

This doesn’t mean that it won’t work. In fact, a lot of customers are pleased with its effectiveness on Amazon and other platforms.

Do pharmacists recommend Prevagen?

According to a Pharmacy Times Magazine survey, most pharmacists recommend this brand, but many believe it’s a total lie.

Being a pharmacist, I don’t think so that more than 70% of all pharmacists will recommend it because the product is based on only one ingredient that is still not fully researched.

I personally recommend all those products or supplements that contain clinically tested, proven and safe ingredients.

Prevagen Alternatives

It is a unique and new nootropic, and there is no other product that contains Apoaequorin. However, some nootropics in the market contain high-quality and premium brain-boosting ingredients. Some of the products are

Verdict—Prevagen Review

To wind up our Prevagen Review, It’s a bit of a mixed bag. 

The customer Prevagen reviews are great, and the regular strength had got 4.3/5 star ratings when the total reviews on Amazon were more than 5500.  

The unique ingredient present in this nootropic is believed to improve short-term memory significantly. It may also help improve concentration, focus, and thinking skills. 

So—If you are looking for a memory booster, this may help you improve your memory and concentration. But please keep in mind that there is no solid evidence to hold up its claims.

Overall, the product has one unproven ingredient but thousands of outstanding verified customer reviews, which makes it worth trying.

In my opinion, I think this stack will work for some people, but it doesn’t provide 100% guaranteed results. Now, This is my personal point of view, and I’m not calling it a useless product.

After reading our “Prevagen Review” and still want to buy this product, it’s totally up to you. But our #1 recommendation will always be Brain Pill®.

Why is Our #1 Recommended Brain Supplements is Brain Pill?

If you don’t want to buy the above products and look for other high-quality brain supplements, We recommend that you try Brain Pill®


Because…!!! Brain Pill uses a blend of high-quality ingredients, plus they put equal weight on long-term brain health.

Although the formula is expensive, it will improve your focus and brain function, reduce stress and anxiety, will increase memory recall and brain cell protection.

And most importantly, they offer you 67 days money back guarantee—which simply means that if you are not satisfied with the results, return it and get back your money. 


Brain Pill

Vitamin D3

Huperzia Serrata,
Gingko Biloba,
Vitamin B6,
Folic Acid,
Vitamin B12, L-
Pantothenic acid.

Price: 100$/60 capsules for extra strength.

Price: 69$/60 capsules

Manufactured by Quincy Bioscience

Manufactured by Leading Health Edge

This article is written by a Registered Pharmacist Manzoor Ahmad (Pharm.D) and medically reviewed by Sajid (PhD in Pharmacognosy).

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