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Leflox Tablet Uses, Side Effects, Dosage, & FAQs

Leflox is the brand name for Levofloxacin which belongs to a group of drugs known as Fluoroquinolones antibiotics. It is a broad spectrum antibiotic and is used in different bacterial infections such as sinuses, skin, lungs, ears, airways, bones, and joints infections. It is most commonly used antibiotic in urinary tract infections and other infections. This article will explore the Leflox tablet uses, side effects, dosage, and frequently asked questions. Quick Overview Product Name: Leflox Manufacturer: Getz Pharma Available Forms: Tablet, Infusion Uses: Respiratory tract infections, sinus infections and urinary tract infections etc. Strengths: Leflox 500mg tablet, Leflox 250mg tablet, Leflox 750mg infusion, Leflox 500mg infusion. Leflox Tablet Uses  Leflox tablets are prescribed for treating various bacterial infections in different body parts. It is effective against a wide range of bacteria and is often utilized for the following conditions: Respiratory Infections: Leflox is commonly used to treat respiratory tract infections, such as bronchitis and pneumonia. It helps in combating bacterial growth responsible for these infections. Urinary Tract Infections: The medication effectively treats urinary tract infections (UTIs) caused by susceptible bacteria. Skin and Soft Tissue Infections: Leflox can be prescribed to treat skin infections, including cellulitis and abscesses. Sinus Infections: It manages bacterial sinus infections that lead to sinusitis. Gastrointestinal Infections: Leflox may be recommended for certain gastrointestinal tract bacterial infections. Prostate Infections: In some cases, it is utilized to treat bacterial infections of the prostate gland. Dosage and Administration Leflox tablets are available in different strengths, with 500mg being a common dosage. The dosage and duration of treatment will depend on the specific infection and the severity of the condition. It’s important to follow the prescribed dosage instructions provided by your healthcare provider. The tablets are typically taken orally with a glass of water, with or without food. It’s essential to complete the full course of treatment even if you start feeling better before the prescribed duration is over. Skipping doses or stopping the medication prematurely may lead to incomplete eradication of bacteria, potentially causing the infection to return or become resistant to the antibiotic. Side Effects of Leflox Tablet  While Leflox can effectively treat bacterial infections, like any medication, it can also be associated with certain side effects. Common side effects may include: Nausea and Vomiting: Some individuals may experience stomach discomfort, nausea, and vomiting. Diarrhea: Leflox can disrupt the normal gut flora, leading to diarrhea in some cases. Headache: Headaches are a possible side effect, although generally mild. Dizziness: Some individuals may feel dizzy or lightheaded while taking Leflox. Photosensitivity: It’s important to note that fluoroquinolone antibiotics like Leflox can increase sensitivity to sunlight, potentially leading to sunburn more easily. Tendon Rupture: Although rare, fluoroquinolones have been associated with an increased risk of tendon rupture, particularly in the Achilles tendon. If you experience any severe or persistent side effects, it’s crucial to contact your healthcare provider immediately. Precautions Before taking levofloxacin, tell your doctor or pharmacist if you are Allergic to it; or other quinolone antibiotics (such as ciprofloxacin, moxifloxacin, ofloxacin); or if you have other allergies. Tell your doctor or pharmacist your medical history, especially: diabetes, joint / tendon problems (eg tendinitis, bursitis), kidney problems, mental disorders (eg depression), certain muscle disorders (myasthenia) severe), nervous problems (eg, peripheral neuropathy), epileptic disorder. Levofloxacin may cause a disease that affects the heart rhythm (prolongation of the QT interval). QT prolongation rarely results in fast / severe (rarely fatal) rapid heartbeats and other symptoms (such as severe dizziness or fainting) that require immediate medical attention. Levofloxacin Mechanism Levofloxacin, a fluoroquinolone antibiotic, operates by zeroing in on a vital bacterial enzyme called topoisomerase or DNA gyrase. These enzymes are central to bacterial DNA processes, including replication and repair. Levofloxacin disrupts their function, leading to twisted or broken bacterial DNA strands, halting their growth and multiplication. This precision targeting is a key feature, as levofloxacin’s mechanism focuses solely on bacterial cells, sparing human cells from harm. By thwarting bacterial DNA integrity, levofloxacin curtails the infection’s progression and provides an effective strategy against various bacterial infections, while its selectivity ensures minimal impact on the host. Drug Interactions with Levofloxacin (Leflox) Levofloxacin, commonly known as Leflox, is a potent antibiotic to treat bacterial infections. However, it’s important to know potential interactions with other medications that could affect their effectiveness and safety. Here’s a summary of key drug interactions to consider: NSAIDs: Combining levofloxacin with non-steroidal anti-inflammatory drugs (NSAIDs) may increase the risk of seizures and tendon issues. Anticoagulants: Levofloxacin can enhance the effects of anticoagulants, leading to an increased risk of bleeding. Corticosteroids: Co-administering corticosteroids with levofloxacin may elevate the risk of tendonitis and tendon rupture. Antiarrhythmics: Levofloxacin can lead to potentially dangerous heart rhythm disturbances when combined with certain antiarrhythmic medications. Antidiabetic Medications: Levofloxacin might affect blood sugar levels and the efficacy of antidiabetic medications like Insulin, requiring careful monitoring. Iron, Zinc, Antacids, and Sucralfate can reduce levofloxacin’s absorption, so it’s advisable to separate their administration by a few hours. Theophylline and Caffeine: Levofloxacin can increase levels of theophylline and caffeine, leading to side effects like rapid heart rate and restlessness. Leflox Tablet Alternatives: Exploring Similar Medications While Leflox (levofloxacin) is a commonly prescribed antibiotic with a wide spectrum of bacterial coverage, several alternative medications offer similar therapeutic effects. Healthcare providers may consider these alternatives based on the patient’s medical history, specific infection, and individual response to treatment. Here are a few notable options for Leflox: Levoxin (Levofloxacin) by Searle Pharma PVT Ltd: Levoxin is a pharmaceutical product by Searle Pharma PVT Ltd that contains levofloxacin as its active ingredient, similar to Leflox. Like Leflox, Levoxin is a fluoroquinolone antibiotic used to treat various bacterial infections. It is available in multiple strengths and formulations, and its usage, dosage, and potential side effects are comparable to Leflox’s. Levo (Levofloxacin) by Ferozsons:  Levo, manufactured by Ferozsons Laboratories, also contains levofloxacin and is utilized to combat bacterial infections. Like Leflox, Levo is effective against various bacterial strains causing infections in different body parts. It is essential to note that

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Nuberol Forte Tablet 650mg/50mg: Uses, Side Effects, Dosage And FAQs

Nuberol Forte is the combination of Orphenadrine and Paracetamol. These two drugs’ combined effect provides relief from the pain associated with skeletal muscle and helps reduce fever. Searle Co Ltd manufactures it. Nuberol comes in 2 strengths; one is Nuberol standard that contains 450mg of Paracetamol and 35mg of Orphenadrine. While the Nuberol Forte contains 650mg of Paracetamol and 50mg of Orphenadrine. Orphenadrine is an anticholinergic and belongs to a class of ethanolamine antihistamines; It is closely related to diphenhydramine. Orphenadrine is commonly used to treat muscle pain and help motor control Parkinson’s disease but has mainly been replaced by new drugs.  While Paracetamol belongs to a class of drugs known as Analgesics, it is a common painkiller used to treat aches and pain. It can also be used to reduce fever. Composition Orphenadrine 50 mg Paracetamol 650 mg. Nuberol Forte Tablet Uses Nuberol Forte is used to treat, prevent or control the following conditions; Best for Muscle spasms, Pain and Fever, Sprains, Relief of painful skeletal muscle spasm, Chronic low back pain, The prolapsed intervertebral disc, Non-articular rheumatism, Tension headache, Muscle injury, Dysmenorrhea, Headache, Toothache, and Ear Pain, Cold and Flu. Note: This drug may also be used for other conditions. Contraindications Nuberol Forte is contraindicated in the following conditions Don’t use it If you are hypersensitive to Paracetamol or Orphenadrine Citrate. If you have Myasthenia gravis, Also, if you are suffering from glaucoma (High pressure in the eye), Don’t use in case of urinary retention, If you are a Lactating woman. Don’t take this medicine After expiry, if the packaging shows signs of tampering. In a child under the age of 12 years. Before you start to take Nuberol Forte, Tell your doctor or pharmacist if; If you are allergic to any other medicines, foods, preservatives, or dyes; Are cardiac patient (Heart Problem) you have any liver or kidney problems; you are taking other Paracetamol-containing products. You have alcohol abuse problems. How does Nuberol Forte work? In Nuberol Forte, Paracetamol’s combined analgesic effect and the relaxing muscle action of orphenadrine citrate provide profound relief of the pain associated with skeletal muscle spasm. Paracetamol has similar analgesic and antipyretic effects as salicylates. Analgesia is mediated at the peripheral and central levels. Orphenadrine citrate is an effective oral muscle relaxant. Muscle relaxation is not based on a direct effect on the muscle itself. The place of action of Orphenadrincitrat is relatively central. Nuberol Forte Interactions Following drugs can interact with Nuberol forte and may aggravate its side effects. Alcohol Ketoconazole Leflunomide Teriflunomide Prilocaine You should avoid these drugs simultaneously and consult your doctor before taking any medicine. Nuberol Forte Dosage The usual recommended dose of Nuberol forte for adults is 1-2 tablets twice daily. You will need to take it orally after food and with a glass of water. Don’t use on empty stomach to avoid stomach upset. This is the usual recommended dose but the actual dose depends on your condition and your pharmacist or doctor will adjust the dose as per your condition. Don’t use more than prescribed, it will do more harm than any good. It is not recommended for use in children. Nuberol Forte Alternatives Various options are available when seeking alternatives to Nuberol Forte tablets, each offering its unique composition and benefits. Here are a few notable options from different pharmaceutical companies: Ridal Forte by Stanley Pharma: Ridal Forte, formulated by Stanley Pharma, is a viable alternative to Nuberol Forte tablets. This medication encompasses a distinctive blend of active ingredients that work synergistically to relieve pain, reduce fever, and alleviate discomfort. Ridal Forte is commonly prescribed for conditions such as headaches, muscle aches, and menstrual cramps, making it a compelling choice for individuals exploring alternatives. Wilgesic by Wilson’s Pharma: Wilgesic, produced by Wilson’s Pharma, is another noteworthy alternative. Engineered to address various types of pain, Wilgesic boasts a carefully crafted formulation that targets pain relief effectively. Its unique ingredients and mode of action make it a suitable option for those seeking an alternative to Nuberol Forte. Provas N by Sami Pharma: Provas N, developed by Sami Pharma, offers a distinct pain management and relief approach. With its specialized formulation, Provas N targets pain at its source and relieves discomfort. This alternative may be particularly beneficial for individuals who require pain relief while considering options for Nuberol Forte tablets. Medigesic by Wilshire Laboratory: Medigesic, a product of Wilshire Laboratory, provides an alternative solution for pain management. This medication is designed to address a range of pain types and offers relief through its carefully chosen combination of active ingredients. Medigesic’s formulation makes it an intriguing option for those exploring alternatives to Nuberol Forte. Sinaxamol by AGP Pharmaceuticals, Pakistan: Sinaxamol, developed by AGP Pharmaceuticals in Pakistan, is another viable alternative to Nuberol Forte tablets. With its unique composition, Sinaxamol aims to provide effective pain relief and manage discomfort. Individuals seeking an alternative option for pain management may find Sinaxamol a suitable choice. Selecting the Right Alternative: The decision to switch to an alternative to Nuberol Forte tablets should be made in consultation with a healthcare professional. Factors such as medical history, existing conditions, and potential interactions with other medications are crucial in determining the most suitable option. Patients are advised to thoroughly discuss with their doctor to make an informed choice that aligns with their specific needs and circumstances. Frequently asked questions (FAQs) 1. Is Nuberol Tablet safe to use when pregnant? It is not recommended for use during pregnancy. Tell your doctor if you are pregnant or intend to become pregnant. 2. Is Nuberol Tablet safe while breastfeeding? It is not recommended for use during lactation. Tell your doctor if you are breastfeeding. 3. Should I use Nuberol Tablet empty stomach, before food or after food? Take this medicine after food with a glass of water. Take Nuberol forte tablets only as directed by your doctor or pharmacist. Do not change the dose unless your doctor tells you to do so. 4. Is Nuberol Forte a Pain Killer? Nuberol contains Paracetamol and Orphenadrine. Both of these

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Cyclopam Tablet: Uses, Side Effects, Dose, & FAQs

Cyclopam Tablet is the combination of Paracetamol, Dicyclomine, and Dicycloverine. It is used to treat, prevent, and control conditions such as irritable bowel syndrome, pain in stomach, period pain, fever, headache, toothache, cold, joint pain, abdominal pain, and other conditions. Indoco Remedies Ltd manufactures Cyclopam Tablet and it is a prescription based medicine. It is composed of the following active ingredients (salts) Paracetamol – 500 MG Dicyclomine – Dicycloverine – 20 MG Cyclopam Tablet Uses It is used for the treatment, control, prevention, of the following diseases, conditions and symptoms: Irritable bowel syndrome Periods pain Painful menstruation Pain in stomach Pain in abdomen Cold Flu Fever Headache Ear pain Joint pain Toothache Your doctor may prescribe it for other conditions. Cyclopam Side Effects Following are some of the side effects associated with the use of this drug. Dizziness Drowsiness Dry mouth Anxiety Excitement Nausea Lethargy Vomiting Feeling of sickness Dryness Confusion Constipation Blurred vision Weakness Decreased sweating Nervousness Headache Heat stroke Light headedness Mydriasis Palpitations Abdominal discomfort Swollen facial features Tachycardia Increase in intraocular pressure Urine retention Urine hesitancy Insomnia Delusions Short-term memory loss Psychosis Incomprehension Coma Gesticulations This is not a complete list of side effects related to this drug. Consult your doctor. Precautions Before using Cyclopam Tablet, please consult a GP especially if you have any of the following conditions: Allergic to Cyclopam tablet or Paracetamol In case of Hypersensitivity reactions. Glaucoma It is not recommended for children & neonates. Do not take paracetamol if you consume alcoholic beverages every day. Should be used with caution in Liver and kidney Disease. Asthma or other breathing problems Breastfeeding Nerve disease. If you have cardiac tachycardia and congestive heart failure. Severe ulcerative colitis Mysthenia gravis. Mechanism Cyclopam Tablet is a combination of two medications: dicyclomine and acetaminophen, which relieve abdominal pain and cramping. Dicyclomin is an anticholinergic that relaxes the muscles of the stomach and intestines. It stops sudden muscle contractions (cramps), relieves pain, bloating and discomfort. Paracetamol / acetaminophen is an analgesic (analgesic) that blocks the release of certain messengers that cause pain. Interaction When It is combined with other medicines and consumed, the risk of drug interactions is high. The effects of all drugs are lost or their salts react and lead to undesirable results. The same case can occur when Cyclopam is consumed in certain diseases. To avoid such interactions, a healthcare professional should know the current medications and any kind of health problem. Here is a list of elements that can interact with Cyclopam tablet and have side effects: It may interact with the following drugs and products: Digoxin Antacids Benzodiazepines Ketoconazole Alcohol Amantadine Antihistamines Corticosteroids Interfere with certain laboratory tests Cyclopam Dose The usual recommended dose is 80 mg daily, in 4 divided doses. Should be consumed 1 hour before meal. For children, the dosage should be prescribed by a doctor as per the condition. Frequently Asked Questions 1. What is Cyclopam tablet? Cyclopam is the brand name for a combination of two active ingredients such as paracetamol and dicyclomine. Paracetamol is an analgesic while dicyclomine is an antispasmodic drug. 2. What are the uses of Cyclopam tablet? It treats irritable bowel syndrome, stomach pain, fever, headache, toothache, cold, joint pain, abdominal pain, etc. Check above for more. 3. What are the side effects of Cyclopam tablet? some of the side effects associated with the use of Cyclopam tablets are Dizziness, Drowsiness, Dry mouth, Anxiety, Excitement, Nausea, Lethargy, Vomiting, Feeling of sickness, Dryness, Confusion, Constipation, Blurred vision, Weakness, Decreased sweating, Nervousness and Headache. Check other side effects above. 4. How long does it take for Cyclopam to work? Most users of Cyclopam Tablet had relief and symptom relief within 24 hours after using Cyclopam. The effect depends, among other things, on the severity of the disease and the dosage. 5. How to take Cyclopam? It may be given at any time according to the doctor’s recommendations. It can be taken before, at or after meals. You should make sure that you do not consume the drug as a whole. Cyclopam should not be chewed, crushed or broken. Take this medicine at the dose and time recommended by your doctor. Swallow it as a whole. Do not chew, crush or break. These tablet can be taken with or without food, but it is best to take it at a fixed time. 6. How does Cyclopam work? The paracetamol in the drug belongs to the category of analgesics and antipyretics. It blocks the synthesis of cyclooxygenase, an enzyme already in our body. This enzyme triggers the synthesis of Prostaglandins, which causes pain, inflammation and redness. While Dicyclomine belongs to the category of cholinergic. It acts as a muscle relaxant and helps to relax the presence in the stomach and intestines (intestines). It works by preventing sudden muscle contractions, also known as cramps. It helps with pain, bloating, cramps and discomfort. 7. Is Cyclopam Tablet safe to use when pregnant? This medicine contain dicyclomine which is not recommended in pregnant women. However take if your gynecologist prescribe it. 8. Is Cyclopam tablet safe while breastfeeding? This drug is not safe in breastfeeding women because it dicyclomine which is contraindicated in breastfeeding. This drug may cross into milk and can harm your baby. 9. Can Cyclopam Tablet be used for periods pain? Yes, One of the listed indication of this drug is to provide immediate relief to patients suffering from menstrual cramps and abdominal discomfort during periods. Although it relieves the symptoms mentioned above, a doctor must be consulted before consuming this medicine. 10. Can I take Cyclopam to relieve pain after a miscarriage? Yes, most of the time, the doctor prescribed it to relieve the pain caused by miscarriage. abdominal pain. Always ask your doctor before using this medicine because it tends to cause serious side effects. 11. Should I use the Cyclopam tablet on an empty stomach before or after a meal? This medicine can be taken with or without food. However, it is advisable to

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Livogen: Uses, Side Effects, Dose & FAQs

Livogen is the brand name of two active ingredients along with some non active ingredients. The active ingredients present in this formulation are Ferrous Fumarate and Folic Acid. Livogen Tablet is mainly used for the treatment of anemia and deficiency of folic acid. It is also used as a supplemental medication for diseases which cause a deficiency of iron and folic acid in the body. It is also used in other conditions. See below Uses. Composition The active present in this formulation are Elemental Iron (Ferrous Fumarate) – 152 mg Folic Acid (Vitamin B9) – 1.5 mg Other Variants Livogen -Z Captab Livogen Hemtonic Syrup Livogen-XT Tablet Livogen Injection Livogen Tablet Uses: This medicine is used in different conditions and symptoms: Anemia During pregnancy Megaloblastic anemias due to a deficiency of folic acid Anemias of nutritional origin, Folate deficiency Anemia in Pregnancy Anemia due to folic acid deficiency Malabsorption of food Celiac disease Mechanism Of Action It works by acting on the bone marrow to produce a normoblastic marrow and promotes the production of blood cells in the body. Other conditions for which livogeni are prescribed as an additional drug include low levels of red blood cells or hemoglobin, infantile anemia and megaloblastic anemia.  It Helps to supply sufficient Elemental Iron or Ferrous Fumarate, which helps in regulating the oxygen supply through RBC to various parts of the body. The Livogen tablet should only be taken with a doctor’s prescription. Your doctor may prescribe different options depending on your health, age and needs. Livogen Side Effects Following  are some of the common side effects associated with the use of Livogen tablet are Biliousness Nausea Constipation Flatulence Allergic reactions Dark or green stools Irritability Bloating Stomach cramps Darker coloured stool Gastric irritation Pain in leg Dark coloured urine Less common side effects include Depression Confusion Easily angered and annoyed Gas Itching Loss of appetite Swelling of the abdomen Not feeling well Over-excitement Rashes Taste problems Sleep disorder Precautions Avoid Livogen tablet and tell your doctor or pharmacist: If you are allergic to any of the ingredients. People with anemia due to vitamin B12 deficiency (pernicious anemia). Hereditary disease that causes too much iron accumulation in the tissue (hemochromatosis). People with anemia due to folic acid deficiency. People with a disorder that affects the iron in the body (hemosiderosis). People with a state of sudden loss of hemoglobin (oxygen that transports proteins in the blood) in the urine during the night (paroxysmal nocturnal hemoglobinuria). People with other diseases that affect hemoglobin, such as sickle cell disease or thalassemia. People with an active gastric ulcer People receive repeated blood transfusions. Inflammatory bowel disease such as ulcerative colitis or Crohn’s disease. Children. Avoid alcohol consumption, especially if having alcoholic cirrhosis Bowel problems Colitis Diverticulitis Crohn disease Type 2 Diabetes Ulcer in intestine Child younger than 4 months old Livogen In Pregnancy & Breastfeeding This medicine is safe during pregnancy. However, you should ask your doctor or midwife if you need to take iron and folic acid supplements during pregnancy. All pregnant women should not take supplements; Your diet may contain enough nutrients. No known harmful effects when this medication is used by nursing mothers. Interaction With other drugs The following medicine can interact with Livogen and may change the effect of this drug Levothyroxine Bisphosphonates, e.g. alendronate Entacapone Levodopa Penicillamine Methyldopa (iron tablets can also reduce the effect of lowering methyldopa blood pressure) ciprofloxacin, norfloxacin, ofloxacin, levofloxacin Zinc and calcium supplements reduce the absorption of iron supplements. Separate the drugs for at least two hours. Oxytetracycline, doxycycline, minocycline, tetracycline Trientene, used to treat Wilson’s disease, also reduces the absorption of iron supplements from the intestine, making them less effective unless the doses are separated by at least two hours. Magnesium carbonate, magnesium hydroxide, aluminum hydroxide and calcium carbonate, can reduce the absorption of iron by the intestine and make the less effective supplements. Separate the drugs for at least two hours. Folic acid can reduce the blood levels of the anti-epileptic drugs phenobarbital, phenytoin and primidone. If you take folic acid in combination with any of these anti-epileptic drugs, your doctor may need to increase the dose of this antiepileptic to keep the seizures under control. Milk, milk-based products, tea, coffee and eggs can reduce the absorption of iron from the intestine, while vitamin C (ascorbic acid) increases it. Dosage The dose of this drug depend on your medical condition. Your doctor will decide the amount of dose. However it is recommended to be taken empty stomach, at least one hour before or two hours after a meal. Along with the dosage recommended for this medicine.  it is very important to follow the diet plan recommended by the doctor or healthcare provider to facilitate better absorption of the medicine. Consume enough iron-rich foods in order to get maximum iron from natural food sources. Frequently Asked Questions 1. What is Livogen? Livogen is a multivitamin supplement composed of ferrous fumarate and and folic acid (Vitamin B9). It is used in different conditions. check it above in Uses Section. 2. What is the use of Livogen? Livogen is a supplemental product mainly used for anemia, pregnancy,  low RBC or hemoglobin count, lack of iron and vitamin B9 supply in diet, childhood anemia, Megaloblastic anemia. and other conditions. 3. What are the side effects of Livogen? The most common side effects associated with the use of this drug are nausea, constipation, allergic reactions, flatulence, Dark or green stools, and dark urine. There are other side effects check above “Side effects”. 4. Can I take Livogen on an empty stomach? Take with food if this medicine cause stomach upset. Ask your pharmacist before using. 5. What happens if i Overdose Livogen? Taking more than prescribed Livogen Tablet may cause harmful side effects. Consult your doctor if you suffer any kind of side effects. 6. What happens if i Miss a dose of Livogen? If missed certain regular dose, take as earliest possible, and if it is time for the next dosage,

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Pantocid (Pantoprazole): Uses, Side Effects, Dosage

Pantoprazole is in a class of medications known as proton-pump inhibitors (PPIs).It is marketed under the brand name Protonix, Pantocid and other. It is prescription drug used as a short-term treatment for gastroesophageal reflux disease (GERD), heart burn,  and acid reflux. Pantocid is manufactured by Sun Pharma Laboratories Ltd. Pantocid Uses It is used in the treatment and prevention of various medical conditions such Gastooesophageal Reflux disease. Gastric ulcers Gastrin secreting tumour Benign gastric ulcer Small intestine ulcer Gastric ulcerative Heart Burn Acid reflux. Zollinger-Ellison Syndrome H. Pylori infection. Your doctor may have prescribed it for another reason. Ask your GP if you have any questions about why Pantoprazole has been prescribed for you. Pantocid Side effects The more common side effects that can occur with pantoprazole (Pantocid)  include: Nausea or vomiting Diarrhea Stomach pain Headache Gas Joint pain Dizziness Serious side effects Serious side effects can include the following: Low magnesium levels. Using this drug for three months or longer can cause low magnesium levels. Vitamin B-12 deficiency from long term use. Severe diarrhea. Bone fractures Kidney damage. Cutaneous lupus erythematosus (CLE). Systemic lupus erythematosus (SLE). Fundic gland polyps (don’t usually cause symptoms) Other reported side effects include: Pancreatitis Liver damage Reduced levels of blood cells Muscle breakdown. Interaction with Medicine Severe interactions occur with Methotrexate Nelfinavir While moderate interaction with Warfarin Digoxin Reduce blood levels of atazanavir or nelfinavir, reducing their effect. Precautions Do not take it if you are allergic to any medicines containing pantoprazole or any of the ingredients in this formulation. Do not use it in combination with antibiotics or other medicines if you are allergic to any of the antibiotics. Do not use it if you have severe liver disease or cirrhosis. Do not use it in combination with atazanavir. It should not be given to children. Do not take this medicine after the expiry date stated on the carton (EXP), or if the packaging is torn or showing signs of tampering. Don’t take If you are pregnant or planning to become pregnant, talk to your doctor. Tell your doctor if you want to breastfeed or breastfeed. Tell your doctor if you have or have had other illnesses. Mechanism Pantoprazole, like other proton pump inhibitors, blocks the enzyme that produces acid in the stomach. Blocking the enzyme reduces acid production, healing the stomach and esophagus. Dose of Pantocid It is common to take pantoprazole 40 mg once a day, in the morning. If you are taking pantoprazole twice a day, take 1 dose in the morning and 1 dose in the evening. Usual adult recommended dose for GERD and healing erosive esophagitis is 40 mg daily for 4-8 weeks. The usual recommended dose for treating Zollinger-Ellison syndrome is 40 mg twice daily. It is generally recommended to take the tablets about 30 minutes before meals for maximum effectiveness. The tablets should be swallowed whole and not crushed, split or chewed. Frequently Asked Questions   1. What is Pantocid 40 mg used to treat? It is the brand name for Pantoprazole. It is used in the treatment and prevention of various medical conditions such as gastroesophageal reflux disease (GERD), heart burn,  and acid reflux. 2. What are the side effect of Pantocid? Common side effects may include: dizziness; stomach pain, headache, gas, nausea, joint pain; vomiting, diarrhea. For complete list of side effects check above uses. 3. What is the best time of day to take Pantocid? It generally is recommended that Pantocid tablets be taken approximately 30 minutes prior to meals for maximal effectiveness. 4. Can you take 2 Pantocid a day? It recommended to take pantoprazole once a day, in the morning. However your doctor will determine the right dose for you based on your medical condition. 5. How Pantocid Works? Pantocid contain pantoprazole which belongs to a group of drugs known as proton pump inhibitors. It blocks the enzyme in the wall of the stomach that produces acid. By blocking the enzyme, the production of acid is decreased, and this allows the stomach and esophagus to heal. 6. Can Pantocid be used as a painkiller? No it is a proton pump inhibitor and should not be used as a painkiller. 7. Can Pantocid Tablet used over a long period of time? No, This medicine cannot be taken over a long period of time unless prescribed by a doctor. Long term use can cause bone fractures and low magnesium levels. 8. Does Pantocid cause gas? Yes, some of the side effects of using Pantocid tablet include gas or flatulence, bloating, and abdominal distension. 9. Can Pantocid cause diarrhoea? Yes, the most common side effects associated with the use of this medicine is diarrhoea. consult your physician if these symptoms persist. 10. Does it have an expiry date? Like any other medication it has an expiry date. Always check the expiry date on the packet before purchasing it. 11. Is it Safe with alcohol? Interaction with alcohol is not known. It is recommended to consult your doctor before consumption. 12. Is Pantocid habit forming? No habit-forming tendencies were reported. 13. Is Pantocid safe to take if I’m pregnant ? It is not generally recommended during pregnancy. 14. Is it safe to take it while i am breastfeeding? Pantoprazole has not been studied in females who are nursing. 15. Can i take Pantocid for long term? Long-term use of pantoprazole may make it difficult for your body to absorb vitamin B-12, which could result in a B-12 deficiency. 16. What if i Missed a Dose of Pantocid? If you miss a dose of pantocid, take it as soon as you remember. You should skip the missed dose if it is almost time for your next scheduled dose. 17. What happens if i overdose Pantocid Tablet? Seek emergency medical treatment or contact your doctor in case of an overdose. But in case of suspicion of overdose, the doctor will start emergency treatment. 18. How long should Pantocid take? Your doctor will tell you how long the tablets should be taken. 19. How to store it?  Store the tablet at room temperature between 15 and 30 ° C and protected

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Skilax (Sulfolax); Uses, Side Effects, Doses

Skilax (Sulfolax) is a laxative used to treat chronic constipation. This is the best and most effective laxative available. Relieving occasional constipation and avoid dry, hard stools. It can also be used for other conditions specified by the doctor. Sulfolax is a stool softener. It works by helping the fat and water in the stool mass to soften the stool. By increasing the amount of water absorbed by the stool in the bowel, the stool becomes softer and easier to overcome. Uses/Indications Skilax Tablets and Skilax Drops both are used for the treatment, control, prevention, conditions and symptoms: Bowel evacuation Constipation Contraindications Skilax is contraindicated in patients with the following conditions Acute surgical abdominal conditions like acute appendicitis, Ileus, Intestinal obstruction, Acute inflammatory bowel diseases, and In severe dehydration. Rare hereditary problems of fructose intolerance should not take this medicine. Known hypersensitivity to sodium picosulfate or any other component of the product. Skilax Side Effects:  Following are some of the side effects associated with the use of Skilax tablets and Drops. Stomach pain Diarrhea Loose motion Cramping Nausea Vomiting Throat Irritation Dizziness Fainting Rashes on skin. This is not a complete list of side effects. Consult your physician. Precautions Before taking this medicine always tell your doctor or pharmacist if you are Allergic to this medicine or any other ingredient Have abdominal pain Nausea Sudden change in bowel Are pregnant or breast feeding Drugs Interactions If you use other medicines or OTC products at the same time, the effects of Skilax drops may vary. This could increase the risk of side effects or prevent the medicine from functioning properly. Talk to your doctor about all the medicines, vitamins and herbal supplements you use to prevent or treat drug interactions. Skilax Drops can interact with the following drugs and products: Amoxicillin Furosemide Doxycycline Prednisolone Dosage Take this medication orally, usually at bedtime with a full glass or as directed by your doctor. Decrease your dose or stop taking this medication if you develop diarrhea. The usual adult dose  1-2 Skilax Tablets once daily  or 10 -15 drops once a day. The usual  recommended dose for Children 2-5 years is  2 – 3 drops once daily, Dose for 6 -10 years old child is  2- 5 drops once daily. The dosage may be adjusted, under medical advice,according to age and symptoms. Drink 6 to 8 glasses of water daily while using any laxative. Frequently Asked Questions (FAQS) What is Skilax drops used for? Skilax is used for Constipation and bowel evacuation. What to if i miss a dose of Skilax? If you miss a dose, use it as soon as you remember. If it is almost time for the next dose, skip the missed dose and continue the dosing schedule. Do not use an extra dose to make up for a forgotten dose. If you regularly lose cans, you should set an alarm or call someone in your family. Please consult your doctor to discuss any changes to the dosing regimen or a new dosing regimen to make up for missed doses if you forget too shortly. What happens if i Overdose of Skilax Drops? Do not use more than the prescribed dose. Taking more drugs will not improve the symptoms. Instead, they can lead to intoxication or serious side effects. If you believe you or someone else has overdid Skilax Drops, contact the nearest hospital or emergency department. Bring a box of medicines, a container or a label to help doctors get the information they need. Do not give your medicine to others, even if you know they have the same problem or if they seem to have the same problem. This can lead to overdose. How to Store Skilax drops ? Store at room temperature, protect from heat and direct light. Do not take any medication unless it is indicated in the package leaflet. Keep medicines away from children and pets. Do not throw medicine into the toilet or throw it into the sewer unless you are invited to do so. The medicines that are rejected in this way can contaminate the environment. Contact your pharmacist or doctor for further information on the safe disposal of Skilax drops. What happens if i take Expired Skilax Drops? It is unlikely that taking a single dose of expired Skilax drops will result in an adverse event. Please discuss with your doctor or pharmacist for advice or to feel bad or not. The expired drug may become ineffective in the treatment of the prescribed conditions. To be sure, it is important not to use the expired medication. If you have a chronic condition that requires constant use of medications such as heart disease, seizures and life-threatening allergies, it’s much safer to stay in touch with your doctor to get a new stock of drugs. without a prescription. expired. Can Skilax drops be used safely during pregnancy? This medication should be used only when clearly needed during pregnancy. Please consult your doctor for specific case recommendations. Is Skilax Drops safe while breastfeeding? It is not known if this drug passes into breast milk. Discuss the risks and benefits with your doctor. Can Skilax Drops be used for constipation and bowel evacuation? Yes, constipation and bowel evacuation are the most commonly reported uses of Skilax drops. Please do not use Skilax Drops for constipation and bowel evacuation before consulting your doctor. Should I take Skilax on an empty stomach before or after meals? You can use it any time but usually at bed time however The dose is based on your medical condition and response to therapy. Decrease your dose or stop taking this medication if you develop diarrhea.it’s better you consult your healthcare provider before use. Can I drive safely with this product or use heavy machinery? If you feel drowsiness, dizziness, hypotension and headache, after taking this medicine it’s recommended to avoid driving a car or operating heavy machinery. Do not drive if you are tired of taking this medication, become dizzy or lower your blood pressure. Can

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Evion 400 (Vitamin E): Uses, Side Effects, Dosage

The active ingredient present in Evion 400 Capsule is Vitamin E. Vitamin E is a powerful lipid-soluble antioxidant that protects cell membranes from free radical damage and prevents the oxidation of LDL cholesterol. Vitamin E is an important nutrient for the vision, reproduction, and health of blood, brain, and skin. Vitamin E helps keep skin and eyes healthy and strengthens the body’s defenses against diseases and infections (the immune system). Vitamin E is naturally present in some foods, is added to others, and is available as a dietary supplement. “Vitamin E” is the collective name for a group of lipid-soluble compounds with pronounced antioxidant activity. Scientists are investigating whether vitamin E can help prevent or delay chronic free radical disease by limiting the production of free radicals and possibly other mechanisms. Evion 400 is manufactured and distributed by Merck Consumer Healthcare Ltd in India. Vitamin E deficiency Vitamin E deficiency is extremely rare in humans because it is unlikely to be caused by a diet low in vitamin E. Symptoms of a vitamin E deficiency include Chronic diarrhea An inability to secrete bile Greasy stools, and Premature low birth weight infants with a weight less than 1500 grams. Natural sources It is naturally found in Vegetable oils like sunflower, wheat germ, and safflower oils are among the best sources of vitamin E. Green vegetables like spinach & broccoli, provide some vitamin E. You can also get some vitamin E from nuts like peanuts, hazelnuts, and almonds. and it’s also found in seeds such as sunflower seeds. Evion 400 Uses Evion 400 Capsule can be used for the treatment and prevention of various medical conditions such as: Vitamin E deficiency, Nocturnal muscle cramps, Liver disease, Painful mensuration, Dyspraxia Parkinson’s disease and more, Tardive dyskinesia, Reduction of risk of coronary artery disease, Cystic fibrosis, Dementia Painful menstruation Kidney problems A genetic disorder like G6PD Nerve damage due to chemotherapy Blood disease Laser eye surgery Nitrate tolerance Bladder cancer Nonalcoholic steatohepatitis Granuloma annulare Prevent hair loss Improve scalp circulation Huntington’s disease Balance oil production Support a healthy scalp Add shine Mechanism Vitamin E in Evion 400 is a fat-soluble vitamin that reacts with free radicals that oxidatively damage the cell membrane without forming another free radical. Evion 400 slows down processes that damage cells. Evion 400 Side effects Common side-effects of Evion 400 are: Diarrhea Nausea Stomach ache Drowsiness Rashes Blurred vision Headache Weakness Some other serious but very rare side effects like allergic reactions, including: Itching Rashes Trouble breathing Swelling Severe dizziness Risk Warnings Read the label carefully before use. Keep out of the reach and sight of children Store in a cool dry place away from direct sunlight. Use under medical supervision. Used with caution and consult your doctor in case of the following diseases. Hypertension, Myopathy, Thrombophlebitis, Fatigue, Weakness, Nausea, Headache, Dizziness, Blurred vision, Flatulence, Diarrhea, Abdominal pain, Contact dermatitis. Precautions Before using Evion 400 Capsule, tell your doctor about Medications, over-the-counter products (vitamins, herbal supplements, etc.), Allergies, If you are pregnant, planning to get pregnant or breastfeeding If you have Diabetes If you Have a history of heart attack, stroke If you have a Bleeding disorder Liver disease Eye disorder Kidney disease Vitamin K deficiency If you are a Patients suffering from or with a history of head and neck cancer Patients allergic to its ingredients Interaction Evion 400 Interactions with different medicines Heparin Warfarin Aspirin Clopidogrel Ferrous fumarate Colesevelam Carbonyl iron Tipranavir This is not a complete list of drug interactions. Evion 400 Dosage The dose of the Evion 400 capsule depends on the advice of the expert doctor. You must not pick things up to change the dose of 400 Evion and stop taking it abruptly. The recommended daily allowance of vitamin E for teens and adult is 15mg per day. The usual recommended dose To improve male fertility, vitamin E 200-600 IU is needed regularly. The usual recommended dose To treat Huntington’s disease at the earliest stage, 3000 IU is needed. The usual recommended dose To get rid of menstrual problems, essentially 200 to 500 IU of Vit E are required. The dosage is usually one Evion 400 capsule per day or as prescribed by the doctor. This depends on the treatment and the degree of reaction of the patient. Dosage changes are not recommended as this may cause side effects. According to a study published at Harvard University that the dose of Vitamin E above 400 mg a day may be harmful. Frequently asked questions  1. Is Evion 400 safe with alcohol? The interactions with alcohol are unknown. It is advisable to consult your doctor before eating. 2. Is Evion 400 a habit-forming drug? No habit has been reported. 3. Is the use of Evion 400 safe during pregnancy? For pregnant women, the use of Evion 400 is only recommended if the need is clearly identified and if the potential benefits outweigh the risks associated with its use. Ask your doctor before use. 4. Is it safe to use Evion 400 during breastfeeding? When feeding mothers, Evion 400 is only recommended if the need is clearly identified and if the potential benefits outweigh the risks associated with its use. Ask your doctor before use. 5. Can Evion 400 be used to treat menstrual problems? Yes, it can be used for menstrual problems. Evion contains tocopherol acetate, which helps reduce the synthesis of prostaglandins (a chemical agent that causes pain in cells), reducing the duration and intensity of pain. 6. Is Evion 400 an antioxidant? It is a vitamin supplement and has several antioxidant properties. The capsule of Evion 400 contains tocopheryl acetate (vitamin E), a natural chemical compound, and full of antioxidants. It helps protect the body from damage caused by substances called free radicals. 7. Can I use Evion 400 for hair loss? Yes, it can be used for hair loss. It has tocopherol acetate, which helps repair, reduces inflammation and damage to the hair follicles. 8. What to do if you overdose on Evion 400?

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Ecosprin (Aspirin): Uses, Side Effects, Dosage

Aspirin is the active ingredient present in Ecosprin. Aspirin is a nonsteroidal anti-inflammatory drug (NSAID). It is used as anticoagulant drug in many different conditions like blood thinning in heart attacks, Cardiac arrest, and stroke. Ecosprin Tablets is available asTablets of 75 mg, 150 mg and 325 mg. Ecosprin Uses Ecosprin can be used for the treatment and prevention of various medical conditions such as For blood thinning in heart conditions Stroke risk Heart attack Acute coronary syndrome Pain and aches Fever Cold Flu Rheumatic fever Pericarditis Joint pain Rheumatic arthritis Migraine Menstruation pain Nerve pain Sore throat Toothache Kawasaki disease How Ecosprin Work?  It works by stopping the production of prostaglandins, substances in the body that cause inflammation. Aspirin inhibits irreversible prostaglandin H synthase (cyclooxygenase-1) in platelets and megakaryocytes, thus blocking the formation of thromboxane A2 (TXA2, a potent vasoconstrictor and platelet aggregate). Reduces the function of platelets and the ability of blood to clot. Aspirin inhibits platelet function differently than other NSAIDs, and its antithrombotic effect lasts longer than other NSAIDs. Therefore, aspirin is used for the prevention of heart attacks and strokes. Precautions Before taking Ecosprin you should get advice from a pharmacist or doctor if you: Are allergic to aspirin Have Allergy to other non-steroidal anti-inflammatory drugs (NSAIDs). Are asthmatic have severe liver or kidney problems have had stomach ulcers in the past Drink alcohol regularly have haemophilia or another bleeding disorder Have uncontrolled hypertension Are pregnant, breastfeeding or trying to get pregnant Are looking for medication for a child under 16  medication containing aspirin shouldn’t be given to children under 16 Are over 65 years of age Avoid or ask your doctor if are taking other medications Ecosprin Interactions Sometimes a medication may make another medication less effective or the combination may increase the risk to the patient. This is called drug interaction. The most common substances that can affect aspirin are: Anti-inflammatory analgesics such as Diclofenac, Ibuprofen, Indomethacin and Naproxen. These can increase the risk of gastric bleeding when taken in combination with aspirin. Selective serotonin reuptake inhibitors (SSRIs), Antidepressants such as Citalopram, Fluoxetine, Paroxetine, Venlafaxine and Sertraline. Take aspirin, this can increase the risk of bleeding. Methotrexate for the treatment of cancer and some autoimmune diseases. Aspirin can make it difficult for the body to eliminate methotrexate, which results in high and potentially dangerous levels of methotrexate in the body. Warfarin, an anticoagulant medication or an anticoagulant that prevents blood from clotting. Taking aspirin with warfarin may reduce the anticoagulant effect of the medication and increase the risk of bleeding. However, in some situations, a doctor may prescribe aspirin with warfarin. This is not a complete list of drug interactions associated with the use of Ecosprin. Ecosprin in Pregnancy and Breastfeeding Taking aspirin during pregnancy can damage the child’s heart before birth, reduce birth weight or have other effects. You should talk to your doctor if you are pregnant or planning to become pregnant while taking aspirin. The drug can also be transmitted to breast milk and cause harm to breastfeeding children. Do not breast-feed while taking aspirin. Ecosprin Side effects 1. Gastrointestinal side effects are, Abdominal burning, Ulcerations Nausea Pain, Cramping, Liver toxicity, Gastritis, and Even serious gastrointestinal bleeding. 2. Daily aspirin can help prevent a clot-related stroke, it may increase your risk of a bleeding stroke (hemorrhagic stroke). 3. Rare Allergic reactions like rashes and hives. 4. Hearing sounds that come from inside your body. (Tinnitus) Ecosprin dosage Ecosprin should be used as directed by your doctor. The usual recommended dose of ecopsrin is below for various medical conditions. Usual recommended dose for Ischemic Stroke is 50-325 mg once a day. Usual recommended dose for Suspected Acute MI is initially160-162.5 mg is administered as soon as an MI is suspected. The maintenance dose of 160-162.5 mg a day is continued for 30 days post-infarction. Usual recommended dose for Prevention of Recurrent MI is75-325 mg once a day. Usual recommended dose for Unstable Angina Pectoris is75-325 mg once a day. Usual recommended dose for Chronic Stable Angina Pectoris is 75-325 mg once a day. Usual recommended dose for Rheumatoid Arthritis is initially 3 g a day in divided doses. Increase as needed for anti-inflammatory efficacy with target plasma salicylate levels of 150-300 mcg/mL. Usual recommended dose for Juvenile Rheumatoid Arthritis is Initially 90-130 mg/kg/day in divided doses. Increase as needed for anti-inflammatory efficacy with target plasma salicylate levels of 150-300 mcg/mL. Missed Dose The missed dose should be taken as soon as possible. It is recommended to skip the missed dose when there is already time for the next scheduled dose. Overdose Seek an emergency or contact your doctor if you overdose. Storage: Ecosprin tablets should be stored at room temperature (15 ° C to 30 ° C). Protect from heat, moisture and light. Get away from the kids. Frequently Asked Questions about Ecosprin 1. What about Ecosprin and alcohol? People who take aspirin on a regular basis are at risk for stomach problems, including stomach bleeding. Alcohol consumption can increase this stomach risk. Ask your doctor if alcohol is harmless in moderation. 2. Is the Ecosprin habit forming ? No tendency for habitual forming  was reported. 3. Is Ecoprine safe during pregnancy? This medicine is not recommended for pregnant women. 4. Is Ecosprin safe in breastfeeding? This medication is not recommended for lactating women. 5. Should I take Ecosprin on an empty stomach before eating or after eating? Ecosprin should be taken after the meal. However, this may not reflect how you should use this medicine. Follow your doctor’s instructions for using this medicine. 6. Is the operation or operation of heavy machinery safe when Ecosprin is used? If drowsiness, dizziness, hypotension and headache are the side effects of Ecosprin medication, it may not be safe to drive a vehicle or operate heavy machinery. In general, it can be safely used while driving or operating a machine. 7. Can I stop using Ecosprin immediately or do I have to slow down its use? Some medications need to be reduced or can not be stopped

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Dart Tablet: Uses, Side Effects, Dosage & 10 FAQs

Dart Tablet is the brand name of an analgesic and antipyretic medicine prescribed for the treatment of headache, pain and fever. This tablet is manufactured and distributed by Juggat laboratories limited. Dart tablet is actually a combination of antipyretic, analgesic and anti-inflammatory medicines. It is used to relax muscles and treat headache, fever, cold, muscle pain, toothache, flu etc. You will need to take take the Dart tablet as prescribed by your healthcare provider. It is recommended to take it with food to avoid stomach upset. Talk to your doctor if you are already taking other medications or if you have any other medical conditions. Also, talk to your healthcare provider if you are pregnant or breastfeeding before using this medicine. Paracetamol Paracetamol, or Acetaminophen, is a commonly used analgesic and antipyretic medication. It effectively relieves various types of pain, including back pain, headaches, and toothaches, while also reducing fever. Widely available over the counter, it is crucial to follow recommended dosage guidelines to avoid potential liver damage, especially in individuals with pre-existing liver conditions. Caffeine There is a small amount of caffeine in this medicine that prevents drowsiness caused by the effect of the other two components. It is a central nervous system stimulant and is most commonly found in coffee beans, tea leaves, and kola nuts. It is one of the most commonly used psychoactive drugs. [1] Propyphenazone Propylphenazone works quickly and effectively for shorter periods of time. It is a derivative of phenazone, an anti-inflammatory analgesic and non-steroidal (NSAID). In addition to analgesic and antipyretic properties, it also has anti-inflammatory properties. Dart Tablet Uses Dart Tablet is a widely used analgesic (pain reliever) and antipyretic (fever reducer) medication. Its primary function is to alleviate pain and reduce fever. This tablet can be used for the treatment and prevention of the following conditions and symptoms: Pain of any origin Migraine Headache Cold Mild to moderate pain Menstrual pain Sore throat Cerebral palsy Drowsiness Ache Cephalalgia Fever Fatigue Bronchopulmonary dysplasia in premature infants. Note: This may not be a complete list of Dart tablet uses. Your doctor may prescribe it for other conditions or in combination with other drugs. Side effects While Dart Tablet can be effective, it may cause certain side effects. It’s essential to be aware of these potential reactions and seek medical attention if they persist or worsen. Here is a list of some very common side effects; Nausea Diarrhea Acidity Gastrointestinal problems like upset stomach, IBS May affect Liver at higher doses Anxiety Nervousness Sleeplessness Skin Rashes Itching Serious side effects Some serious side effects which may be very rare but If you notice such side effects consult your doctor immediately. Breathing problems like Asthma, Dyspnea Anaphylaxis – Swelling of face Blood loss – Decrease in the number of blood cells may happen Contraindications Dart Tablet is contraindicated  for use in the following conditions If you are hypersensitive to any of the ingredients in this tablet. Chronic active alcoholism, Increased sensitivity to paracetamol, In the patients suffering Porphyria disorder. Marked disturbances of liver function and kidney disease, Anaemia, Pregnancy. Consult your doctor for proper guidance in such cases Dart Tablet Precautions Avoid Dart Tablet; If you have an allergic disorder like asthma or any other allergic symptoms. If you are pregnant and breastfeeding women If You have a history of heart disease, depression, low blood pressure. If you are suffering stomach ulcer, any inflammatory bowel disorder like ulcerative colitis or Crohn’s disease If you are allergic to any other medicines (Like as aspirin, naproxen, and ibuprofen), or to any other NSAIDs. Avoid in High blood pressure suffering patients. Caution should be taken in Patients suffering from heart problems or any blood vessels related problems, or blood clotting problems If your kidney or liver-related problems. You are taking any other medication. Interactions Dart Tablet may interact with the following medicines and products: Oral birth control pills Phenytoin Warfarin Cimetidine Ephedrine Mexiletine Disulfiram Fluoroquinolones This is not a complete list of drug interactions and conditions that might interfere with the Dart Tablet. Before taking this drug, inform your GP about all your present medications. How does it work? Dart is an analgesic-antipyretic. It has an analgesic, antipyretic and weak anti-inflammatory effect. The mechanism of action is related to the inhibition of prostaglandin synthesis, the predominant influence on the thermoregulatory centre in the hypothalamus, and improves heat transfer. However, it is believed that Acetaminophen acts primarily in the central nervous system and increases the pain threshold by inhibiting any isoform of cyclooxygenase, COX-1, COX-2 and COX-3 enzymes involved in prostaglandin synthesis (PG), Propyphenazone is an NSAID derived from pyrazolone and related to phenazone. It has antipyretic and analgesic properties. Three main mechanisms of caffeine action on the central nervous system have been described. The mobilization of intracellular calcium and the inhibition of specific phosphodiesterases occur only at high non-physiological concentrations of caffeine. The only likely mechanism of action of methylxanthine is antagonism at the adenosine receptor level. Caffeine increases the energy metabolism in the entire brain, but at the same time reduces the cerebral blood flow and leads to relative cerebral hypoperfusion. Caffeine activates norepinephrine neurons and appears to affect the local release of dopamine. Dart Tablet stimulates the central nervous system; antagonizing adenosine receptors; Blocking the action of cyclooxygenase in the body. Dart Tablet Dosage The appropriate dosage of Dart Tablet is crucial for its effectiveness and to minimize the risk of adverse effects. It’s important to follow the recommendations provided by healthcare professionals or as indicated on the medication packaging. Here are general guidelines for the dosage of Dart Tablet: For Adults: The typical prescription for adults is often two tablets per day. It is advisable to take the tablets during meals or immediately afterward to mitigate the risk of stomach upset. For Children and Elderly Patients: Dart Tablet is not recommended for use in children and elderly patients without specific guidance from a healthcare provider. Dosage adjustments may be necessary based on individual health conditions

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Ciplox (Ciprofloxacin): Uses, Side Effects, Dosage

Ciprofloxacin  (Brand Name: Ciplox)belongs to a group of broad-spectrum antimicrobial drugs known as fluoroquinolones. It is the most active second generation fluoroquinolone against a wide range of bacteria that are susceptible to Gram-negative aerobic rods, especially the Enterobacteriaceae Neisseria. Ciplox is manufactured by Cipla Ltd. Ciplox Uses Ciprofloxacin (Ciplox) works against a variety of infections, some of which are difficult to treat. Due to its broad spectrum, its oral effectiveness and its good tolerability, it is often used to treat infections, but should not be used for minor infections. or anaerobes are mainly causative. in severe cases, treatment by intravenous infusion may be initiated, then continue with the oral. Ciplox is used to treat bacterial infections, for example: Urinary tract infections (UTIs) caused by certain bacteria such as E. coli. Cervical and urethral gonorrhea due to Neisseria gonorrhoeae Skin infections Bone infections Typhoid Joint infections Uncomplicated acute cystitis Chronic bacterial prostatitis Meningitis Pulmonary or respiratory tract infections, for example, tuberculosis, lower respiratory tract infections, and chronic bronchitis) Pneumonia and sepsis caused by Yersinia pestis (Y. pestis). Infectious diarrhea caused by E. coli, Campylobacter jejuni, and Shigella. Prophylaxis of infections in neutropenic / cancer patients and other sensitive patients. Patients with anthrax with fever and low white blood cell count as well as intra-abdominal infections. Ciprofloxacin (Ciplox) is effective against Staphylococcus aureus and Staphylococcus epidermidis.It is active against susceptible strains of Staphylococcus aureus and is not effective against Methicillin-Resistant Staphylococcus aureus. Ciprofloxacin (Ciplox) has a very good activity against gram-negative bacteria, but enterococci, Streptococcus group A, B, D and streptococcal viridans with moderate susceptibility to ciprofloxacin. Mechanism of action Of Ciprofloxacin (Ciplox) Ciprofloxacin (Ciplox) inhibits the synthesis of DNA in bacteria by inhibiting the bacterial topoisomerase enzyme DNA (DNA gyrase). This prevents relaxation of the supercoiled DNA and thus prevents normal transcription and replication in the body. Fluoroquinolones also inhibit TopV topoisomerase, which is likely to prevent the separation of DNA replication in two daughter cells. In this way, ciprofloxacin prevents the division or multiplication of parent organisms. Fluoroquinolone major mechanism of action is that they act on a group of enzymes called topoisomerases. But what actually happens inside the bacteria that kill it.We will answer that in-depth mechanism how normally topoisomerases work and what are they doing in bacteria and then we will explain what ciplox is doing with these bacteria. Normal Function of Topoisomerases: You know bacterial DNA is a double helix Circular chromosome. They are like other DNA which are twisted around each other but for Growth and replication of the cell we need to Separate these two strands because for growth of the cells we need to make proteins and to synthesize protein  we need to do transcription (which is a process of making RNA from DNA)and for that we have to first separate the double helix DNA. Let’s suppose we open/separate a single strand. By separating it the separated parts will become loose but the tension will move to the periphery this is called positive supercoiled. But with the time as we separating double strand they become overtwisted and we can’t continue the process of transcription. so there a special enzyme that starts working here is called topoisomerases. How is Topoisomerase Working? Topoisomerases type 2 (DNA gyrase) are going to solve the problem of over twisting.Topoisomerase work on the overtwisted area of the DNA. This Enzyme has two functional domains, one domain is cutting the overtwisted DNA to relax it and the other domain is resealing it again. The first Domain is called nuclease domain while the other is called ligase domain. This is a normal mechanism of action of Topoisomerases. How Ciplox Work ? When we give the patient Ciprofloxacin (Ciplox) it enter into Bacteria by passive diffusion and approached Topoisomerases enzyme. They bind to DNA gyrase domain of the enzyme and block or inhibit it so the other domain (nuclease)  keep on cutting the overtwisted DNA but the Ligase point Can’t reseal it because of Ciprofloxacin and in the end all the bacteria divided into fragments and bacterial death occur. Therefore, it destroys the existing bacteria that are causing the infection, and it inhibits the growth of new bacteria. Ciplox Pharmacokinetics It is rapidly absorbed orally, but the diet delays the intake and first-pass metabolism occur. The key feature of ciprofloxacin is high tissue penetration. The concentration in the lungs, sputum, muscles, bones, prostate, and phagocytes exceeds that of the plasma. It is excreted mainly in the urine, both glomerular filtration and tubular secretion. Urinary and biliary concentrations are 10 to 50 times higher than those of plasma. Ciplox in Pregnancy & Breast Feeding Ciplox is contraindicated in pregnancy because ciprofloxacin has caused arthropathy in animal studies. However, to prevent a secondary case of meningococcal meningitis, a single dose of ciprofloxacin may be used. Ciplox is not recommended for use in breastfeeding women unless absolutely necessary. Ask your doctor before using this drug. Ciplox Side effects Ciprofloxacin ( Ciplox ) has a good safety profile and side effects are present in only 10% of cases, but they are generally mild. Here are some of the side effects associated with the use of Ciplox. Nausea, vomiting, and diarrhea may occur. Black or tarry stools Ciprofloxacin may affect the clearance of theophylline and cause an increase in serum concentration. White patches on the tongue and in the mouth. Headaches, insomnia, dizziness, liver problems and rashes can sometimes occur. Ciplox can cause tendonitis, which is a serious complication in adults and can cause tendon rupture. Although tendonitis occurs rarely (some cases have been reported), but is more common in elderly failure, renal failure, and renal failure in people with corticosteroids. Skin / Hypersensitivity are rashes, itching, photosensitivity, swelling of the lips, urination, and swelling of the lips. Serious skin reactions are rare. The use of ciprofloxacin (Ciplox) for long periods can lead to oral candidiasis or a new yeast infection such as white spots in the mouth, a change in vaginal discharge. Ciprofloxacin Interaction Some medicines may

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