Leflox (Levofloxacin): Uses, Side Effects, Dosage, & FAQs

Leflox is the brand name for Levofloxacin which belongs to a group of drugs known as Fluoroquinolones antibiotics. It is a broad spectrum antibiotic and is used in different bacterial infections such as sinuses, skin, lungs, ears, airways, bones, and joints infections. It is most commonly used antibiotic in urinary tract infections and other infections.

Leflox Uses

Leflox can be used in the treatment and control of different infections such as

  • Urinary tract infections
  • Sinus infection
  • Skin infections
  • Ears infections
  • Bones and Joint
  • Airways
  • Lungs infections
  • Diarrhea caused by E.coli, Campylobacter jejuni, and Shigella bacteria.
  • Breast infections
  • treating plague caused by Yersinia pestis.
  • Inhalational anthrax
  • Pneumonia


For oral dosage forms (oral solution or tablets)

  • Usual Adult dose for infection are 250 to 750 milligrams (mg) once a day For 3-14 days.
  • Usual Adults Dose For treatment and prevention of plague  is 500 milligrams (mg) once a day.
  • Usual Adults Dose For preventing anthrax infection  is 500 milligrams (mg) per day in a single dose for 60 days.
  • In childrens  dose of levofloxacin   must be determined by your doctor.

Side Effects

The most common reported side effects are:

  • Diarrhea
  • Nausea or vomiting
  • Constipation
  • Headache

Less common side effects include:

  • Dizziness
  • Difficulty sleeping
  • Abdominal pain
  • Abdominal gas
  • Rash
  • Itching
  • Rare allergic reactions

Possible serious side effects of levofloxacin include:

  • Central nervous system effects
  • Peripheral neuropathy
  • Hypoglycemia
  • Clostridium difficile-associated diarrhea
  • Sun sensitivity
  • Abnormal heart beats
  • Hyperglycemia
  • Liver dysfunction


Before taking levofloxacin, tell your doctor or pharmacist if you are

  • Allergic to it; or other quinolone antibiotics (such as ciprofloxacin, moxifloxacin, ofloxacin); or if you have other allergies.
  • Tell your doctor or pharmacist your medical history, especially: diabetes, joint / tendon problems (eg tendinitis, bursitis), kidney problems, mental disorders (eg depression), certain muscle disorders (myasthenia) severe), nervous problems (eg, peripheral neuropathy), epileptic disorder.
  • Levofloxacin may cause a disease that affects the heart rhythm (prolongation of the QT interval). QT prolongation rarely results in fast / severe (rarely fatal) rapid heartbeats and other symptoms (such as severe dizziness or fainting) that require immediate medical attention.


All Fluoroquinolnes antibiotics Work On an enzyme which is called topoisomerase or DNA Gyrase.

Levofloxacin works by killing the bacteria that are causing an infection. You should only use this drug to treat bacterial infections.


Taking levofloxacin with certain medications raises your risk of side effects from those drugs. Examples of these drugs include:

  • Diabetes drugs, such as Insulin, nateglinide, pioglitazone, repaglinide, and rosiglitazone.
  • Warfarin.
  • Nonsteroidal anti-inflammatory drugs (NSAIDs).
  • Theophylline.
  • Antacids that contain iron, calcium, zinc, or magnesium should be taken at least 2 hours before or 2 hours after levofloxacin.

Consult your doctor before using a combination of drugs.

Frequently Asked Questions

1. What is leflox used for?

Leflox contain a broad spectrum antibiotics that is used in different infections such as skin, sinus, bone and joint and urinary tract infections. check above for more.

2. Is levofloxacin safe to take?

This drug has black boxed warnings. A black boxed warning is the most serious warning from the Food and Drug Administration (FDA). It alerts doctors and patients about drug effects that may be dangerous.

This is a broad spectrum antibiotics and a prescription drug. This need a doctor prescription as self prescribing is dangerous.

3. How are the side effects of Levofloxacin (Leflox)?

Common side effects associated with the use of Levolfoxacin include Diarrhea, Nausea or vomiting, Constipation, and Headache. There are other side effects too you can check above.

4. Is it Safe with alcohol?

Interaction with alcohol is not known. Please consult your doctor before consumption.

5. Is it habit forming?

No habit forming tendency has been reported.

6. Is levofloxacin good for UTI?

Levofloxacin is commonly used to treat urinary infections, including those resistant to other antibiotics, as well as prostatitis (infection of the prostate).

7. Is Leflox safe in pregnancy?

This medicine is generally not recommended for use in pregnancy unless absolutely necessary and only under the supervision of a doctor.

8. Is Leflox Safe while while breast-feeding?

This medicine is not recommended for use in breastfeeding women unless absolutely necessary since it may affect the development of the infant’s joints. Use only if clearly needed and only under the supervision of a doctor. Avoid breastfeeding for 4 to 6 hours after a dose to decrease the exposure of the infant to the levofloxacin in breast milk.

9. How to take Levofloxacin (Leflox)?

Levofloxacin tablets may be taken with meals or on an empty stomach. This medicine is best taken with a full glass (8 ounces) of water. Several additional glasses of water should be taken every day, unless otherwise directed by your doctor. Drinking extra water will help prevent some unwanted effects of levofloxacin.

10. How To store It?

Store this drug at 20°C to 25°C. Don’t store this medication in moist or damp areas, such as bathrooms.

11. What happens if i miss a dose of Lefox (Levofloxacin)?

Take the miss dose as soon as you can, but skip it if it is almost time for your next dose. Do not take two doses at one time.

12. What happens if i overdose Leflox (Levofloxacin)?

Seek emergency medical attention or call the Poison Help line

1 thought on “Leflox (Levofloxacin): Uses, Side Effects, Dosage, & FAQs

  1. Levaquin is NOT safe if a doctor prescribes it to you, are you kidding me? Shame on you!! Just because a doctor prescribes it to does not make it safe! There are now 5 black box warnings for Levoflox. It should only be taken as the last resort and only when there are no alternatives.
    Adverse effects have included death. I took 4 pills 3 years ago for an infection I didn’t have and haven’t been able to work since. You can take this drug multiple times before crossing a threshold and end up crossing a brick wall and entering a hell from which you may never totally recover.
    I am a former moderator for the Fluoroquinolone Toxicity support group wjth a membership of ten thousand poor souls poisoned by this class of antibiotic, people who go from doctor to doctor, often being gaslighted along the way, looking for a cure that doesn’t exist. Many symptoms can’t currently be confirmed by testing. Wake up and investigate thoroughly before making such statements!
    I will die before I let anyone put me through the utter horror of floxing.