Manzoor (Pharm-D)

Facts Checked by DrugsBank Team

ACE inhibitors

Drugs Brands                    Generic Aceon                      Perindopril Altace                      Ramipril Accupril                  Quinapril Capoten                  Captopril Vasotec                   Enalapril Prinivil, Zestril      Lisinopril Lotensin                 Benazepril Univasc                   Moexipril Monopril                Fosinopril Mavik                      Trandolapril Mechanism of action They inhibit the converting enzyme which is responsible for the conversion of angiotensin 1 into angiotensin 2. Angiotensin 1 is a decapeptide that is formed from a plasma protien alpha globulin (angiotensinogen)by the action of renin. Renin is formed in the kidney.Angiotensin 1 is converted into angiotensin 2 by the converting enzyme in the blood vessels of the lungs that is an octapeptide. Angiotensin 2 is a powerful vasoconstrictor and it causes increased production of aldosterone from adrenal cortex.Aldosterone then causes the increase reabsoprtion of salt and water from the renal tubules.Angiotensin 2 is converted into angiotensin 3 that also increase the secretion of aldosterone from the adrenal cortex. Thus both angio 2 and angio 3 are responsible for increase in BP. Also ACE inhibitors prevent the destruction of bradykinin by angitensin converting enzyme that further decrease the blood pressure by causing dilation of peripheral blood vessel. Bradykinins is also a potent vasodilator but it partialy acts by causing the release of nitric oxide and prostacylin. Bradykinin is also responsible for causing cough and angioedema in some persons using ACE inhibitors. Uses ACE inhibitors are used for: Controlling high blood pressure Treating left ventricular dysfunction and heart failure Preventing and treating kidney disease (nephropathy) in people with hypertension or diabetes Preventing strokes   Side effects: Side effects may include dry cough,low blood pressure (hypotension),high potassium levels (hyperkalemia), dizziness,angioedema,reduced kidney function. Pregnancy: Do not use this medicine if you are pregnant, breastfeeding, or planning to get pregnant. If you need to use this medicine, talk to your doctor about how you can prevent pregnancy.  

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Beta Blockers

These Drugs are classified Into Two Main Groups; Beta 1 + Beta 2 Blockers Beta 1 Blockers Beta 1 And Beta 2 Blockers Generic Brand Propranolol  Inderal Pindolol  Visken Penbutolol  Levatol Nadolol  Corgard Carteolol  Ocupress Timolol  Blocadren Sotalol  Betapace     Mainly Beta 2 Blockers: Genric Brand Acebutolol  Sectrol Atenolol  Tenormin Alprenolol  Aptin Betaxolol  Kerlone Celiprolol  Selectol Esmolol  Brevibloc Metoprolol  Lopressor, Toprol-XL) Uses : Beta-blockers are a group of prescription drugs and may be used to treat the following Conditions High Blood Pressure Heart Attack Angina Atrial Fibrillation Less commonly used for glaucoma  (as eye drops), Tremor, Anxiety conditions and Hyperthyroidism. Mechanism Of Action: Beta blockers, also called beta-adrenergic blocking agents, inhibit the release of the adrenaline and noradrenaline in certain parts of the body. This results in a slowing of the heart rate and reduces the force at which blood is pumped around your body. Beta-blockers are drugs which make your heart beat more slowly and with less force. Beta-blockers can also block angiotensin II In the kidney which results in lowering the blood pressure.   Beta Blockers Side effects   A slow heart rate and dizziness. One of the ways in which beta-blockers work is to slow down your heart rate. If it becomes too slow, you may feel dizzy. If you’re worried that your heart rate is too slow, see your doctor. Cold hands and feet. You may need to wear gloves and thick socks in cold weather. You may notice this most when you first start taking beta-blockers or if your dose is increased. Other side-effects can include: visual disturbances sleep disturbance, including nightmares  Erectile dysfunction is occasionally a problem for some men who take beta blockers. Note : Make sure you tell your GP if you have a history of: Allergic reaction to any medications Asthma Kidney disease Heart disease Diabetes It’s Very Important To Talk To Your GP Or HealthCare Provider Before Stopping Beta Blockers Because Stopping it suddenly could cause problems such as palpitations, a recurrence of angina pain or a rise in blood pressure.

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Classification Of Antianginal Drugs

Angina Pectoris  Angina pectoris is a disease that often occurs due to deposition of lipids material inside the coronary arteries. This causes narrowing of the coronary arteries and the patient feels Throbbing pain in the chest during exertion because narrowed arteries cannot cope with Increased demand of blood supply by the heart during physical exertion or mental stress. There are three main type of angina ; 1. Angina Of Effort This type of angina in which chest pain occurs during physical or mental stress is known as angina of effort. 2. Variant Angina Another less common type of angina occurs at rest due to spasm of the coronary arteries.This is known as variant angina or prinzmetal angina. 3. Unstable angina. A third Type of angina in is known as unstable angina in this type the disease is severe and patient feel pain in the chest even with a slight degree of exertion.This is s serious condition and if not treated can lead to myocardial infarction.Thus angina pectoris can be of the following three type; Classification Of Drugs Drugs Used in treatment and prevention  Of angina can be classified into three main groups; Organic Nitrates and Nitrites Nitroglycerin Isosorbide Dinitrate Isosorbide mononitrate Amyl nitrite.      2. Calcium Channel Blockers These can be further  divided into two groups; Dihydropyridines Amlodipine Nicardipine Nifedipine Nimodipine Nisoldipine Nitrendipine     2. Miscellaneous Drugs Verapamil Diltiazem Bepridil    3. Beta-Adrenoceptor Blockers These can be further subdivided into two groups; Beta 1 and Beta2 Antagonist Propranolol Penbutolol Pindolol Satolo Timolol Beta 1 Selective Blockers Metoprolol Atenolol Esmolol Acebutolol Betaxolol In case you’ve got stable angina (the most frequent kind ), you’re going to be given medication to consider when you experience an angina attack. You might even use glyceryl trinitrate  (GTN) to prevent an assault prior to doing something such as exercise. You could have a headache, itching or flushing soon after using it. Glyceryl trinitrate pills usually expire about 8 weeks following the package is started, at which point you will want to substitute them. GTN spray lasts considerably longer, so can be more suitable. To help avert more strikes, you will also must take at least 1 other medication daily for the rest of your life. Some people will need to take two or more medications. If you can not have either of these medications, you could be given another medication like ivabradine, nicorandil or ranolazine. Angina is a warning sign that you are in a greater risk of severe problems such as heart attacks or strokes. You might also have to take additional medicines to decrease this threat. These include:low-dose aspirin to stop blood clots and statins to Lower Your cholesterol (blood glucose ) amount while ACE inhibitors to Lower Your blood pressure Surgery Surgery may be recommended when medications are not helping control your angina. Both these operations are likewise powerful. The very best one for you depends upon your own circumstances. If surgery is recommended, speak with your physician or doctor about your alternatives. You are probably going to have to keep on taking some medications after operation. In case you’ve got unstable angina (where symptoms grow unpredictably), then you will need medicines to reduce blood clots and lower your chance of experiencing a heart attack or stroke. Surgery (either CABG or PCI) might be recommended if you’ve got a high risk of getting a different angina attack, or else you are at a higher risk of experiencing a heart attack or stroke.

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Metronidazole: Uses, Side Effects, Dosage

Metronidazole is a bactericidal drug.Available formulations -oral, intravenous, intravaginal, and topical.Brand Name Of Metronidazole is Flagyl. Mechanism of action The drug affects DNA replication by Blocking the production of nucleic acid. The activity of metronidazole against amoebae, Trichomonas,  and Giardia is also likely to be attributable to disruption of existing DNA and inhibition of its synthesis in those organisms.Due to this reason, Bacteria can’t survive. Indications With Doses Flagyl (Metronidazole)  is an antibiotic that is used to treat a wide variety of infections. It works by stopping the growth of certain bacteria and parasites.They May be used to treat;   1. Flagyl is Used to treat bacterial vaginosis. The usual dose is 400-500 mg twice a day for 5-7 days Or 2 grams as a single dose. 2.Also Used to Treat  Amebiasis In Acute Intestinal Amebiasis (Acute Amebic Dysentery) Usual Dose is 750 mg orally 3 times a day for 5 to 10 days And For Amebic Liver Abscess The Usual Dose Should be 500 to 750 mg orally 3 times a day for 5 to 10 days 3. Metronidazole in combination with other agents is used for Eradicating Helicobacter pylori bacteria from the gut in people with peptic ulcers. Bismuth quadruple therapy: A Dose of 250 mg orally 4 times a day clarithromycin-based triple therapy: A dose of 500 mg orally twice a day.Duration of therapy is 10 to 14 days pressure sores and leg ulcers that are infected with anaerobic bacteria. 4. Pressure sores and leg ulcers that are infected with anaerobic bacteria. Children 8 weeks-12 years: 20-30mg/kg/day as a single dose or divided into 7.5mg/kg every 8 hours for 7 days. Children under 8 weeks: 15mg/kg/day as a single dose or divided into 7.5mg/kg every 12 hours. 5. Painful inflammation and ulcers of the gums (ulcerative gingivitis). Adults and children over 10 years: 200mg three times a day. 6. Bacterial dental infections, eg dental abscesses. Extended-release Tablets: 750 mg orally once a day for 7 consecutive days 7. Bacterial infections in the abdomen (peritonitis). In Case Of oral administration Usual Dose Is 7.5 mg/kg orally every 6 hours for 7 to 10 days. In Case of Intravenous administration Usual Loading dose is 15 mg/kg IV once infused over 1 hour and then Maintenance dose is 7.5 mg/kg IV infused over 1 hour every 6 hours For 7 to 10 daysAbscess in the pelvic cavity, usually a result of an abdominal infection. 8. Bacterial infections of bone (osteomyelitis). In Case Of Intravenous Dose, Loading dose Of  15 mg/kg IV once infused over 1 hour Then Maintenance dose Of 7.5 mg/kg IV infused over 1 hour every 6 hours for 7 to 10 days.Don’t Exceed 4 g per day. In Case Of Oral Dose Immediate-release capsules and tablets 7.5 mg/kg orally every 6 hours For 7 to 10 days.Don’t Exceed 4 g per day. 9. Used For The Treatment Of Liver Abscess In Case Of Intravenous administration, Loading dose Should be  15 mg/kg IV once infused over 1 hour Then A Maintenance dose Of 7.5 mg/kg IV infused over 1 hour every 6 hours for 7 to 10 days In Case Of Oral Administration, Immediate-release capsules and tablets 7.5 mg/kg orally every 6 hours   Note : This antibiotic treats only certain bacterial and parasitic infections. It will not work for viral infections (such as common cold, flu). Using an antibiotic when it is not needed can cause it to not work for future infections.   Metronidazole side effects More common side effects The more common side effects that can occur include: Nausea or vomiting Diarrhea Metallic taste Headache Loss of appetite Heartburn Constipation Cramping in your stomach area   Serious side effects nervous system effects, including seizures and encephalopathy (abnormal brain function). Symptoms can include: Convulsions (sudden movements caused by tightening of your muscles) Dizziness Headache Confusion Ataxia (loss of control of body movements)     Warnings and precautions Talk to your doctor, pharmacist or nurse before taking Metronidazole tablets: if you are in the 2nd and 3rd Trimester of pregnancy if you have ever suffered from any liver disease if you have kidney disease, particularly if you require dialysis treatments if you have epilepsy or have ever had fits if you have been exposed to any sexually transmitted disease. if you have porphyria (a genetic disease that can cause skin blisters, abdominal pain and brain/nervous system disorders) if you have any nervous system disorders if you have any disorder of the blood.    

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Medical Tests you should Have once a year

Blood pressure . High pressure is very dangerous.It kills your brain, your heart, your eyes, and your kidneys. Do not let high blood pressure sneak up on you. get it tested. It’s simple; it’s cheap; and it’s fast. Cholesterol Profile. Do you have high cholesterol? find out a minimum of once every five years (more oftentimes if you are at risk for a heart attack). controlling your cholesterol will add years to your life. Blood Sugar. Untreated diabetes will destroy your health, causing cardiovascular disease, renal disorder, and blindness. do not let it. Get a fasting blood glucose test at least once each 3 years and take control of diabetes early. Screening colonoscopy is suggested for everybody at 50 years old. Stepping on the scales. At the age 40-50  most of the people start gaining weight. Watch this weight gain carefully, and fight back with healthier eating and exercise. Being overweight puts you at high risk for developing a number of diseases — and studies show that weight loss will improve your odds. Looking for moles: Love your skin. Check your skin monthly for any uncommon spots or moles. make certain to raise your doctor to see your skin once a year, as well. Protecting your eyes. Vision-robbing diseases become more common as you age. make sure to get your eyes examined frequently — each two to four years until age 54 so every 1 to 3 years after that. Go more often if you have got vision issues or risk factors for eye problems. Checking your immunizations. individuals over age fifty should get a flu shot once a year. and do not forget, even healthy individuals need a tetanus booster shot every 10 years, and one among those should contain the pertussis vaccine for whooping cough. make certain to ask your doctor to update any immunizations that you might need. consider hepatitis A and B vaccines if you haven’t already had them. And after age 60 you ought to be vaccinated against the herpes virus that causes shingles. For women only: Breast test and mammogram. At this age, do not ever let a year go by without obtaining a mammogram and having your doctor examine your breasts for any changes. Early detection of {breast cancer|carcinoma} can save your breast and your life. Pelvic exam and pap smear. Combining a pap test with a person’s papillomavirus (HPV) test can safely extend the interval between cervical cancer screenings from 3 years to 5 years in many women between the ages of 30-65. women over age 65 will stop getting screened if they’ve had a minimum of 3 consecutive negative Pap tests or at least 2 negative HPV tests among the previous 10 years, according to the guidelines. however women who have risk factors for cervical cancer like smoking, a history of HPV, or a more advanced precancer diagnosis should still be screened till they reach the age of 80. Source: Webmd

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10 Tips how to Lose Your Weight Fast But Safely

1. Eat lots of vegetable and fruits Fruit and veg are low in calories and fat, and high in fibre ..3 essential ingredients for productive weight loss. They additionally contain lots of vitamins and minerals. 2. Do not skip breakfast Skipping breakfast will not help you melt off. you’ll miss out on essential nutrients and you’ll find yourself snacking more throughout the day because you feel hungry. 3. Use a smaller plate Using smaller plates will assist you eat smaller portions. By using smaller plates and bowls, you’ll be ready to gradually get used to eating smaller portions without going hungry. It takes about twenty minutes for the stomach to inform the brain it’s full, thus eat slowly and stop eating before you feel full. 4. Exercise Being active is vital to losing weight and keeping it off as well as providing various health advantages, exercise will facilitate burn off the excess calories you cannot cut through diet alone. 5. Drink lots of water People typically confuse thirst with hunger. You’ll find yourself consuming further calories once a glass of water is basically what you need. 6. Eat high-fibre foods Foods containing many fibre will help keep you to feel full, that is perfect for losing weight. Fibre is barely found in food from plants, like fruit and veg, oats, wholegrain bread, rice and pasta, and beans, peas and lentils. 7. Do not ban foods Don’t ban any foods from your weight loss plan, particularly those you prefer. banning foods can only cause you to crave them more. there is no reason you cannot enjoy the occasional treat as long as you keep within your daily calorie allowance. 8. Do not stock food To avoid temptation, try to not stock food – like chocolate, biscuits, crisps and sweet fizzy drinks – at home. Instead, choose healthy snacks, like fruit, unsalted rice cakes, oat cakes, unsalted or unsweetened popcorn, and fruit juice. 9. Avoid Alcohol A standard glass of wine can contain as much calories as a chunk of chocolate. Over time, drinking too much can easily contribute to weight gain. 10. Plan your meals Try to set up your breakfast, lunch, dinner and snacks for the week, ensuring you stick with your calorie allowance. you’ll notice it useful to make a weekly shopping list.  

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Pharmacology Classification

Antacid:Reduce production of hydrochloric acid in the stomach. Antianemics: Increase the production of red blood cells. Anticholinergic :Decrease Oral Secretion. Antirheumatics :Antirheumatics include drugs, which are used to treat the symptoms of rheumatoid arthritis Anticoagulants: Prevent the formation of clot. Antitussives:Antitussives are medicines that suppress coughing, Anticonvulsant :Management of Seizure and Bipolar disorder. Antidiarrheal :Reduce water in bowels and gastric motility. Antihistamine:Block the release of Histamine. Proton Pump Inhibitors:Used for stomach ulcer. Antihypertensive:Decrease Blood Pressure. Anti-infective :To get rid of infections. Bronchiodilators:Dilate bronchi and bronchioles. Diuretics:Increas excretion of water and sodium. Laxatives:Loosen stool and increase bowel movement. Miotics:Constricts pupils of eye Mitotic:Dilates Pupils. Norcotic/Analgesics:Pain Relievers. NSAIDs:Non Steriodal anti inflammatory drugs :Used in Pain and inflammations. Probiotics:Probiotics are live bacteria and yeasts that are beneficial for health. They are often referred to as ‘good’, ‘helpful’ or ‘healthy’ bacteria. ACE inhibitors:ACE inhibitor blocks the angiotensin-converting-enzyme from converting angiotensin I to angiotensin II. Anthelmintics: are a type of medicine that kills helminths. Helminths are worm-like parasites such as flukes, roundworms, and tapeworms. Antidiabetic :Antidiabetic agents refer to all the different types of medicine involved in the treatment of diabetes. Antidotes:An antidote is a drug, chelating substance, or a chemical that counteracts (neutralizes) the effects of another drug or a poison. Antifungal:Antifungal agents are also called antimycotic agents. They kill or inactivate fungi and are used to treat fungal infections (including yeast infections). Contraceptives are the medicines and other devices that are used to prevent unwanted pregnancy. Decongestants are medicines that relieve congestion by reducing swelling, inflammation and mucus formation. H2 antagonist:H2 antagonists block histamine-induced gastric acid secretion from the parietal cells of the gastric mucosa (lining of the stomach).

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5 Ways How to Prevent & Treat H.pylori

Stomach Ulcer Is Caused By A Bacteria Called Helicobacter Pylori (H. Pylori). This bacteria Live In The Stomach and Cause Infection Of The Stomach Wall Which In Turn Cause Irritation and inflammation And Ultimatly Cause Ulcer. This Usualy Happens During Childhood. A great many people don’t understand they have H. Pylori contamination, since they never become ill from it. On the off chance that you create signs and indications of a peptic ulcer, your specialist will most likely test you for H. pylori contamination, since it can be treated with anti-infection agents. This Bacteria is Also the Main Cause Of Stomach Cancer In Some people.But When The Symptoms Do Occur They May include Loss Of Appetite Abdominal Pain,Bloating,nausea,And Weight Loss.More Then Half Of The World Population Is living With H.Pylori. The rate of Helicobacter pylori contamination is more in creating nations where certain basic measures of sanitation are now and then, Compromised. The contamination is infectious, but specialists are still uncertain of the method of transmission. It is trusted that contact with a contaminated individual’s defecation, i.e., while doing the clothing or while cleaning the restroom or with tainted water or sustenance can bring about transmission of the microorganisms. Tips To Prevent The Infection: 1) Wash your palms very well: on account that the primary shape of transmission of the H. Pylori micro organism is through touch,you nee to continually exercise right personal hygiene and hand washing. You need to wash your fingers thorough and regularly, particularly after the use of the restroom or before dealing with meals.Proper hand washing begins with warm water, as a minimum 120 degrees, and a respectable sized supporting of liquid cleaning soap. area the cleaning soap on your palms and moist them briefly. Wash them for a complete of 15-30 seconds, scrubbing around your fingers, along the back and front of your arms, and round your fingernails. Then rinse them inside thewarm water and dry them with a easy, sanitized towel or smooth paper towel. 2)Avoid Food That Cause Infection Of H.Pylori: Process Food And simple Sugar Are The Main Foods That Cause H.pylori. Sugar is a perfect domain for the microscopic organisms to flourish and thus, ought to be stayed away from. Chocolate, dairy, red meat, handled and Fast foods, abundance salt, and mixed refreshments ought to be prohibited from the eating regimen. Foods that Kill helicobacter pylori are more compelling in lightening the manifestations of the disease. Mastic gum, acquired from a tree gum Pistacia lentiscus, is accepted to destroy helicobacter pylori from the oral cavity and stomach. Sulforaphane, which is rich in broccoli and cruciferous vegetables like cauliflower, is likewise viewed as powerful against Helicobacter pylori. 3)Stop interacting with those infected: if you are married to or in a relationship with a person infected or when you have a member of the family who has H. Pylori, you have to be very careful together with your interactions with them. if you are married or relationship someone infected, do not kiss them or interact in any type of sexual activity till they had beentreated for the contamination. also keep their toothbrush, cups, and utensils in a one of a kind place so the micro organismcan’t be transmitted via saliva. You need to additionally now not allow anybody on your circle of relatives with the bacterial contamination prepare meals, serve drinks, or contact things that are consumed so that they can not transmit the bacteria by chance via contact or different contamination 4)Get examined. If a member of the family gets unwell with the bacterial infection, you need to get checked as properly. In terms of prevention, eradication is a massive a part of keeping off the bacteria inside the future. due to the fact that it’s miles spread via bad hygiene and sanitary situations inside families, it’s far encouraged that, to get rid of H. Pylori from your own family, all family participants get examined for the H. Pylori microorganism. If a family member is fantastic, they need to be dealt with then retested for the micro organism after four weeks of treatment. Reinfection can occur and begin the cycle over if you do no longer make certain that the bacteria is eradicatedfrom the complete family. 5)Supplements,vitamins And Nutrients: Supplements: Supplements for helicobacter pylori sufferers incorporate expanded admission of carotenoids, vitamins A and C, and zinc. They are accepted to build the capacity of the coating of the stomach to repair and recover. Probiotics supplements are likewise valuable to expand the number of inhabitants in helpful or well disposed microscopic organisms in the digestion systems. Multivitamins and mineral supplements compensate for the lack because of poor retention from Food. Common supplements for H pylori incorporate those got from admission of specific nourishments. Garlic and citrus seeds are considered to have antibacterial properties, while mastic gum and berberine are accepted to help in the destruction of the microscopic organisms. vitamins: vitamins for helicobacter pylori sufferers want to be supplemented because the presence of the bacteria hinders the absorption of vital nutrients. diet C is believed to prevent the micro organism from sticking to the lining of the intestines. it is also considered effective in gut healing. nutrition B12 deficiency is also visible in H pylori sufferers because the intestines cannot take in the nutrient properly. usually, the belly produces the intrinsic element to absorb vitamin B12 from the food. however, the H pylori bacteria hinder the production of this intrinsic component. as a result, the sufferers suffer from the deficiency of B12 and need to be given supplements. Nutrients: Nutrients for H pylori consist of a food plan rich in nutrients A and C. they’re discovered in abundance in fresh fruits,carrots, spinach, candy potatoes, apricots, and parsley. these nutrients resource in preventing the H pylori micro organism from sticking to the partitions of the stomach. as a consequence, the prevalence of infection is significantly decreased. extendedintake of iron and B-complicated is also essential to make up for his or her diminished absorption due

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Top 8 Cancer causing Foods to Avoid

1. Salted, Pickled, and smoked Foods: These products generally contain preservatives, like nitrates, that are meant to prolong period of time. The additives utilized in processed foods will accumulate in your body over time. Eventually, such toxins cause harm at the cellular level and cause diseases like cancer. once preserved foods are roasted at high temperatures, the nitrates are converted to the much more dangerous nitrites. 2. Microwave Popcorn: From the chemically-lined bag to the particular contents, microwave popcorn is at the center of lung cancer debates round the world. Not solely are the kernels and oil likely GMO (which the manufacturer doesn’t got to disclose) unless organic, the fumes released from artificial butter flavourer contain diacetyl, that is poisonous to humans. create your own organic popcorn the old-fashioned way – it tastes better, doesn’t release poisonous fumes, and could be a healthier alternative for you.2. hydrogenated Oils: Vegetable oils are with chemicals extracted from their source, chemically treated, and more chemicals are added to alter the smell and taste. They’re filled with unhealthy omega-6 fatty acid fats (that Americans already consume way too much of) and are tested to change the structure of our cell membranes.3. Canned Goods: Most cans are lined with a product known as bisphenol-A (BPA), that has been shown to genetically alter the brain cells of rats. several plastic.   3. Hydrogenated Oils : Vegetable oils are with chemicals extracted from their source, chemically treated, and more chemicals are added to alter the smell and taste. They’re filled with unhealthy omega-6 fatty acid fats (that Americans already consume way too much of) and are tested to change the structure of our cell membranes.3. Canned Goods: Most cans are lined with a product known as bisphenol-A (BPA), that has been shown to genetically alter the brain cells of rats. several plastic   4. Alcohol: when tobacco use, alcohol abuse is that the leading cause of cancer. though it’s true that a moderate or low quantity of alcohol will truly reduce heart-disease risk, overindulgence may result in failure and stroke. And cancer. in a very meta-study, specialists working for the world Health Organization finished that excessive alcohol use is the main cause of mouth, esophagus, liver, colon, mouth, rectum and female breast cancers. stick with one glass of wine per day for ladies, 2 for men. go with one of these best wines for weight loss.5. process Red Meat: while grilled food will taste delicious, scientists have discovered that preparing meats in this manner – particularly processed meats like hot dogs – releases a carcinogen known as heterocyclic aromatic amines. once you grill red meat to the point of 5. Process Red Meat: while grilled food will taste delicious, scientists have discovered that preparing meats in this manner – particularly processed meats like hot dogs – releases a carcinogen known as heterocyclic aromatic amines. once you grill red meat to the point of cooked, it changes the chemical and molecular structure of the meat. You’re at an advantage baking, broiling, or making ready meat in a skillet than on the grill.6. Soda and carbonated Beverages: Sodas are at the center of the health discussion for 2 decades as 6. Soda and carbonated Beverages: Sodas are at the center of the health discussion for 2 decades as a significant cancer inflicting food. full of high-fructose corn syrup (HFCS), dyes, and a number of different chemicals, they’re terribly bad for every side of your health. they supply zero nutritionary value and rob your body of the nutrients you get from different foods. Adding “diet” to the label suggests that you’re additionally likely consuming aspartame – that is not any better than rat poison to human cells.7. White Flour: once Sodas are at the center of the health discussion for 2 decades as a significant cancer inflicting food. full of high-fructose corn syrup (HFCS), dyes, and a number of different chemicals, they’re terribly bad for every side of your health. they supply zero nutritionary value and rob your body of the nutrients you get from different foods. Adding “diet” to the label suggests that you’re additionally likely consuming aspartame – that is not any better than rat poison to human cells. 7. Farmed Fish: Studies have shown that farmed salmon contain high levels of PCBs, mercury and dioxins — 3 cancer-causing chemicals. commercial fish farming involves raising an unbelievable number of fish (such as salmon), in a very crowded setting. over 60 minutes of the salmon consumed in the united states comes from a farming operation wherever they’re treated with antibiotics, pesticides, and different carcinogenic chemicals to undertake and control the microorganism, viral, and parasitic outbreaks that result from cramming such a lot of fish in a very small area. Farmed fish additionally don’t have the maximum amount omega-3 fatty acid as wild salmon. 8. Refined Sugar: The biggest cancer causing food (by far) is high-fructose corn syrup (HFCS) and different refined sugars. Even refined sugar is extremely refined white sugar with a number of the removed molasses added back certain  flavor and color. Refined sugars (and foods made with them) are the supply of major insulin spikes and feed the growth of cancer cells. Since the majority of the sugar offer within the U.S. is formed using genetically modified (GMO) sugar beets, a healthier choice is organic honey, coconut sugar, or maple sugar. currently that oncologists are using diabetes medication to fight cancer cells, there’s no doubt (finally) that those mutated cancer cells love sugar. Source : thetruthaboutcancer

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10 Signs That You Are Diabetic

Highlights According to Diabetes.org  “Diabetes is a serious life-long health condition that occurs when the amount of glucose (sugar) in the blood is too high because the body can’t use it properly” . In 2016, there were more than 29 million people in the U.S. with diabetes, and 86 million with pre-diabetes. There are some signs and symptoms of this disease which can help us understand and diagnose in the early stage. According to Centers for Disease Control and Prevention, about 1/3 of diabetic patients don’t know that they have diabetes but majority of people show some early signs and symptoms. Signs And Symptoms 1. Frequent Urination-(Polyuria) Normally your body reabsorbs glucose as it passes through your kidneys. But when diabetes pushes your blood sugar up, your kidneys may not be able to bring it all back in. This causes the body to make more urine, and that takes fluids. 2. You Feel Thirsty Than Usual-(Polydepsia) When your body lose more water in urine you will feel thirsty.People often drink plenty of fruit juices which further increse level of sugar in blood.so its better to avoid sugary liquids and foods. 3. Feeling Hungry (Polyphagia) According diabetes.co.uk “An increase in hunger is usually a response to normal things such as intensive exercise or other strenuous activity, but polyphagia can also be the result of more severe issues such as depression or stress”. In uncontrolled diabetes where blood glucose levels remain abnormally high (hyperglycemia), glucose from the blood cannot enter the cells – due to either a lack of insulin or insulin resistance – so the body can’t convert the food you eat into energy.This lack of energy causes an increase in hunger. Simply eating will not get rid of the hungry feeling of polyphagia in people with uncontrolled diabetes, as this will just add to the already high blood glucose levels. The best way to lower blood glucose levels is to exercise as this can help to stimulate insulin production and reduce blood sugar levels.” 4. Dry mouth. Individuals suffering from type 1 and type 2 diabetes are at risk of developing dry mouth (xerostomia). Abnormal insulin production and/or absorption rates, which occur in diabetes, can cause the salivary glands to not release adequate amounts of saliva. According to experts, diabetes is likely the most frequent metabolic disease with salivary implications, due to the ever increasing numbers of people impacted by the disease. 5. Weight Loss: Diabetic Patient urinate more due to which you lose water and calories in urine and that is the reason you lose weight but once you start controlling your blood sugar you may experience some weight gain.   6. Tiredness: Normally when you eat something for energy it breakdown and our cells used it but in case of diabetes your body don’t break the food and you are not getting the feul your body needs.This may cause tiredness.   7. Blurred vision Long-term uncontrolled diabetes can lead to high blood sugar levels that cause damage to small blood vessels over time. This damage can lead to problems with part of the eye called the retina which can create blurred vision. 8. Slow healing The immune system and the processes that help the body heal don’t work so well when your sugar levels are high. 9. Urinary tract infections Higher levels of sugar in pee and the vagina can become a breeding ground for the bacteria and yeast that cause these infections.Recurrent infections are particularly worrisome.So if You are facing urinary tract infection more frequently its time to check your sugar level. 10. Headache: A common symptom of high or low blood glucose is a headache. Headaches alone aren’t harmful, but they can signal that your blood sugar is out of its target range. If you have frequent headaches, diabetes may be to blame. Jen Reviews also discuss How to Manage Your Type 2 Diabetes with Diet

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