Spironolactone (Brand: Spilactone) is potassium sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules.
Spilactone used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis.
Its effects on the endocrine system are all used in the remedies of hirsutism and acne however they May Lead to adverse effects.
Spilactone Tablet is manufactured By Sun Pharma.
It’s also used to treat:
Spilactone works by blocking aldosterone action. Aldosterone is a chemical produced by the body which could lead to water retention. This makes certain kidney, heart, and liver ailments worse. By blocking aldosterone, your own body will not keep fluid. This procedure also prevents potassium from being excreted from the body.
Spilactone may decrease your blood pressure by blocking aldosterone’s impact on blood vessels.
Spironolactone (Spilactone) carries a black-box warning to tumor threat, as a result of chronic toxicity studies that reveal spironolactone can lead to tumor growth in rats.
Spironolactone (Spilactone) should not be used with potassium-supplementing medications or diets since the excess potassium intake can lead to hyperkalemia, which may result in abnormal heart rhythms (arrhythmias).
This medication can let you get enlarged breasts (gynecomastia). This sometimes happens in both women and men. If this happens, your physician may stop your therapy with this medication. This symptom usually goes away as soon as you stop taking this medication.
Your health care provider will monitor your blood pressure and kidney function as you take this medication.
Spilactone is contraindicated in case of Hypersensitivity.
It is also contraindicated in conditions like anuria, hyperkalemia, Addison’s disease, and severe renal failure.
The common side effects that can occur with spironolactone contain:
Serious side effects and their symptoms may contain the following:
Some research indicates that spironolactone has the capability to feminize male fetuses during early pregnancy and lead to endocrine difficulties in late pregnancy by inhibiting the action of penile hormones (androgens). Generally, diuretics like spironolactone are not advocated for pregnant ladies.
Spironolactone could pass into breastfeeding, but hasn’t yet been reported to cause problems in nursing babies.
If you use other medications or over the counter products in precisely the exact same time, the consequences of Spilactone Tablet can alter. This might increase your chance for side-effects or trigger your medication to not operate correctly. Tell your doctor about all the drugs, vitamins, minerals, and herbal supplements You’re using, so You physician can help you prevent or handle drug interactions
Some products which may interact with spilactone include:
Spironolactone (Spilactone) can be taken with or without meals.
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