Brands

Anastrozole (Arimidex): Uses, Side Effects, Dosage

Anastrozole (Brand name: Arimidex) belongs to a group of drugs called aromatase inhibitors. Anastrozole reduces estrogen levels in postmenopausal women, which might impede the development of specific kinds of breast tumors that need estrogen to grow in the human body. It is a type of hormone treatment (also called hormone treatment) and belongs to a group of medications known as aromatase inhibitors. Anastrozole (Arimidex) is the generic (non-branded) name of this medication. All brands include exactly the exact same dose of this medication. Consequently, the quantity of estrogen that the tumor is exposed to is reduced, limiting the development of the tumor. Men with breast cancer might also be given anastrozole, though tamoxifen is much more commonly utilized. Arimidex Uses Anastrozole is used in the treatment of the following conditions For adjuvant treatment of hormone receptor-positive breast cancer, Hormonal treatment of breast cancer in postmenopausal women. Used to treat pubertal gynecomastia. McCune-Albright syndrome. Arimidex Mechanism of Action Anastrozole is a nonsteroidal aromatase inhibitor. It works by blocking aromatase, an enzyme that causes increased levels of estrogen in postmenopausal women. Consequently, estrogen levels in the body are diminished, as well as the increase of cancer cells that rely on estrogen can be stopped or slowed. Aromatase inhibition Contributes to a decrease in tumor and serum concentration of estrogen, resulting in a decreased tumor mass or delayed progression of tumor growth in certain women Arimidex Side effects Like most hormonal treatment drugs, anastrozole may cause unwanted side effects. A number of Arimidex side effects may be serious so it’s important to see the comprehensive information below. How hormonal treatment impacts individuals changes from person to person. Your physician or nurse can speak with you about this and provide you suggestions for the best way best to handle Arimidex side effects. Arimidex side effects are different in different people. Following are some of the side effects related to this drug. Some common Arimidex Side effects are; Pain, Arthritis, Hot flashes, Headache, Depression, Nausea, Vomiting, Bone pain, Sleeplessness, and Rash Serious Arimidex side effects are: Low red blood cell count Weak or broken bones Blood clots Stroke, heart attack Cancer of the lining of the uterus Low white blood cell count Increased blood pressure Stevens-Johnson syndrome Liver inflammation Cataracts. Anastrozole in Pregnancy & Breastfeeding Anastrozole isn’t advisable for pregnant moms under any conditions. Anastrozole can cause fetal damage and terminate maternity. It Shouldn’t Be administered to nursing moms to avoid any injury to the newborn. Precautions In case you haven’t gone through menopause you shouldn’t take anastrozole. Avoid if you’ve got osteoporosis (a condition that causes your bones to become thinner and weaker than normal) Avoid if you have issues with your kidneys or liver. If you are currently taking any other medicines, including medicines you may buy without a prescription, like herbal and complementary medicines Interaction with other medications Anastrozole (Arimidex) shouldn’t be used with tamoxifen since tamoxifen can decrease anastrozole amounts within the body and lessen its curative outcomes. Estrogens reduce the impact of anastrozole by raising estrogen levels in the human body. Foods To Avoid When Taking Anastrozole While taking Anastrozole, most individuals can maintain a regular diet. However, if you experience diarrhea, it’s advisable to avoid raw fruits, vegetables, whole-grain foods, cereals, and seeds. Instead, opt for soluble fiber-rich foods to alleviate diarrhea. Additionally, consider reducing your intake of spicy foods, caffeine, alcohol, and refrain from smoking for overall well-being during Anastrozole treatment. Always consult your healthcare provider for personalized dietary guidance. Arimidex Dosage Anastrozole is generally taken once every day. Follow all instructions on your prescription label. Don’t take this medication in smaller or larger quantities or for longer than advised. The suggested Arimidex dosage for adults such as the elderly is just one 1 mg tablet once each day. For postmenopausal women using hormone receptor-positive early invasive breast cancer, the recommended length of adjuvant hormone therapy is 5 years. You might take anastrozole with or without meals. You might want to continue taking this medicine for as many as five decades. Follow your physician’s directions. But if it’s almost time for the next dose, skip the missed dose and return to your regular dosing schedule. Don’t double doses. Store at room temperature away from heat and moisture. Related article: More Medicine Brands

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Spironolactone (Spilactone): Uses, Side Effects, Dose

Spironolactone (Brand: Spilactone) is a potassium-sparing diuretic that acts by antagonism of aldosterone in the distal renal tubules. Spilactone is used mainly in the treatment of refractory edema in patients with congestive heart failure, nephrotic syndrome, or hepatic cirrhosis. Its effects on the endocrine system are all used in the remedies of hirsutism and acne; however, they May Lead to adverse effects. Sun Pharma manufactures Spilactone Tablet. Spilactone Uses It’s also used to treat: Critical hypertension (hypertension having an unknown origin ) High aldosterone level Hypokalemia (potassium deficiency) Acute heart failure Edema (fluid retention) from different ailments, including congestive heart failure, kidney disease, and cirrhosis (liver scarring). Acne in women Excess hair growth in women (hirsutism) Mechanism of Action Spilactone works by blocking aldosterone action. Aldosterone is a chemical produced by the body that could lead to water retention. This makes certain kidney, heart, and liver ailments worse. By blocking aldosterone, your own body will not keep fluid. This procedure also prevents potassium from being excreted from the body. Spilactone may decrease your blood pressure by blocking aldosterone’s impact on blood vessels. Black Box Warning Spironolactone (Spilactone) carries a black-box warning of tumor threat as a result of chronic toxicity studies that reveal spironolactone can lead to tumor growth in rats. Spironolactone (Spilactone) should not be used with potassium-supplementing medications or diets since the excess potassium intake can lead to hyperkalemia, which may result in abnormal heart rhythms (arrhythmias). This medication can let you get enlarged breasts (gynecomastia). This sometimes happens in both women and men. If this happens, your physician may stop your therapy with this medication. This symptom usually goes away as soon as you stop taking this medication. Contraindications Your healthcare provider will monitor your blood pressure and kidney function as you take this medication. Spilactone is contraindicated in case of Hypersensitivity. It is also contraindicated in conditions like anuria, hyperkalemia, Addison’s disease, and severe renal failure. Spilactone Side Effects The common side effects that can occur with spironolactone include: Nausea and vomiting Diarrhea and stomach cramping. High potassium levels Leg cramps A headache Dizziness Infection Irregular menstrual cycle or bleeding after menopause. itching Serious side effects and their symptoms may contain the following: Allergic responses. Electrolyte and fluid issues. Dangerously high potassium levels. Breast enlargement (gynecomastia). Spilactone in Pregnancy & Breastfeeding Some research indicates that spironolactone can feminize male fetuses during early pregnancy and lead to endocrine difficulties in late pregnancy by inhibiting the action of penile hormones (androgens). Generally, diuretics like spironolactone are not advocated for pregnant ladies. Spironolactone could pass into breastfeeding but hasn’t yet been reported to cause problems in nursing babies. Interactions If you use other medications or over-the-counter products at precisely the same time, the consequences of Spilactone Tablet can alter. This might increase your chance of side effects or trigger your medication not to operate correctly. Tell your doctor about all the drugs, vitamins, minerals, and herbal supplements You’re using so Your physician can help you prevent or handle drug interactions. Some products which may interact with spilactone include: Specific hormones (ACTH), Lithium, Digoxin  Medications that might raise the amount of potassium in the blood (such as amiloride, cyclosporine, eplerenone, tacrolimus, triamterene, and birth control pills containing drospirenone). Spilactone Tablets may interact with Aspirin and Carbenoxolone. Spilactone Dose Spironolactone (Spilactone) can be taken with or without meals. The dose range is 25-400 mg per day in single or divided doses. The initial dose for treating edema in adults is 100 mg daily as a single dose or divided doses. The dose could be corrected five times based on the response. The first dose should be continued for at least five days prior to increasing the dose. When there’s absolutely no adequate answer after five days, another diuretic may be added. The dose for healing hypokalemia is 25 to 100 milligrams daily. The dosage for treating hypertension (hypertension) is 50 to 100 milligrams per day in single or divided doses. If an overdose is suspected, contact a poison control center or emergency room immediately. If you forget a dose, take it when you remember. When it’s near the time of the next dose, skip the missed dose and restart your regular dosing schedule. Don’t double the dose. More Medicine

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Nasacort Nasal Spray (Triamcinolone acetonide): Uses, Side Effects, Dosage

Nasacort Nasal Spray contain Triamcinolone acetonide and can be used to treat itching, coughing, and runny nose brought on by seasonal allergies or hay fever. Uses Nasacort Nasal Spray can be used in the treatment and prevention of the following conditions: Seasonal Allergies like itching, coughing, Runny nose Nasacort Nasal Spray prevents the release of compounds from the body that cause inflammation. It’s a steroid spray which may help improve nasal congestion and might be helpful to decrease snoring and as an adjunctive treatment for obstructive sleep apnea when allergic rhinitis is current. Triamcinolone nasal may also be utilized for different functions not listed in this medication guide. Precautions Nasacort shouldn’t be used if you have an open wound or ulcer inside your nose. The use of this medication in pregnancy shows adverse effects in animals and use in lactation is unknown. If you’re nursing or pregnant, you need to go over the security and risks versus rewards with your doctor. If you’ve had recent therapy with other corticosteroid drugs, you might not wish to utilize Nasacort. Certain eye conditions like increased intraocular pressure, glaucoma, or cataracts might be a contraindication. In case you have an untreated disease, particularly with tuberculosis, herpes simplex impacting the eye, or exposure to measles or varicella (chickenpox), Nasacort ought to be used with care. It might not be a good idea to use it in case you suffer from recurrent nosebleeds (epistaxis). Children must be followed closely if long-term usage happens. Contraindications Nasacort is contraindicated in patients with a history of hypersensitivity to triamcinolone acetonide or to any of the other ingredients of this preparation. Mechanism Nasacort nasal spray includes the active ingredient triamcinolone acetonide, which is a form of medication called a corticosteroid (or steroid). Corticosteroids are hormones produced naturally by the adrenal glands which have many important functions, including control of inflammatory responses. When administered to the nose, then triamcinolone is absorbed into the tissues of the nasal lining. It works by preventing those cells by releasing substances which trigger inflammatory and allergic responses. Additionally, it may help alleviate associated eye symptoms such as itchy, red and watery eyes. Side effects The most Frequent side effects after nasal inhalation of Nasacort (triamcinolone acetonide) are: Increased cough, Nausea or vomiting, Sore throat, Nasal itching and soreness, Nasal congestion, Sneezing, Nasal burning, Bloody nasal discharge, Depression, Acne, Increased hair growth Irregular menstrual cycles, Nasal dryness. Other adverse effects reported with intranasal triamcinolone acetonide contain: Headache , Nausea , and watery eyes. Nasacort Spray in Pregnancy & Lactation Significant complications (like cleft palateand births) have been reported if oral corticosteroids were administered during maternity . It’s not known if the tiny amounts of corticosteroids which show up in the blood after intranasal use take the identical risk. Triamcinolone acetonide use during pregnancy ought to be avoided unless your doctor feels that the possible therapeutic benefit outweighs the possible risk to the embryo. It’s unknown if triamcinolone acetonide collects in breast milk. But, it’s understood that other corticosteroids are excreted in breast milk. The consequences on the child, if any, are still unknown. Nasacort Spray Interactions Inform your doctor about all the medications you take, including non-prescription and prescription medications, vitamins, minerals, and herbal nutritional supplements. Especially tell your Physician if you take: Antibiotics Amphotericin B Anticholinesterase agents like donepezil, rivastigmine, and galantamine. Aminoglutethimide Anticoagulants like warfarin Non-steroidal anti inflammatory agents like aspirin, Naproxen, and celecoxib. Antidiabetic agents Isoniazid Digoxin Phenytoin Ketoconazole Cholestyramine Cyclosporine Estrogens, Carbamazepine Rifampin This isn’t a comprehensive list of all Nasacort drug interactions. Consult your physician or pharmacist to learn more. Dosage Use exactly as prescribed by your physician. Don’t use in smaller or larger quantities or for longer than advised. Follow the instructions on your prescription label. Adult: 2 sprays in each nostril once daily. Reduce dose as symptoms improve. Children: Age less than 2yrs: not suggested. Age 2-6yrs: 1 spray in each nostril once daily. Age 6-12yrs: 1 spray in each nostril once daily; max 2 sprays in each nostril once daily. Note: If you forget to use your Nasacort nasal spray utilize it as soon as you remember, unless it’s almost time for your next dose. In this scenario just leave out the forgotten dose and take the next dose as normal. Do not use a double dose to make up for a missed dose.

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Isotretinoin (Zenatane): Uses, Side Effects, Dosage

Isotretinoin (Zenatane) is an effective systemic medication used in the treatment of severe inflammatory acne. Isotretinoin is categorized as a retinoid created from a synthetic form of vitamin A. This medication can have severe side effects, but it has to be treated and supervised by a healthcare provider. Isotretinoin is a medicine used for treating severe acne. It’s occasionally utilized in the avoidance of certain skin cancers. Isotretinoin is an oral medication used for the prevention and treatment of acute acne. Acne results from inflammation of the skin. The we Food and Drugs Administration approved Isotretinoin in May 1982. Precautions (Zenatane) Before taking isotretinoin, tell your Physician if you or Anybody in your family has any of the conditions like Diabetes, asthma, liver disease, heart disorder and depression. You should also tell your doctor if you are allergic to any medications, particularly parabens (compounds used in cosmetics, moisturizers, and isotretinoin). Do not take isotretinoin if you have hypervitaminosis A. Be sure to tell your doctor if you are taking any other medicines, even over-the-counter medicines. Do not take isotretinoin if you have severe liver disease. Do not take isotretinoin if you have very high-fat levels (cholesterol, triglycerides) in your blood. Mechanism Isotretinoin (Zenatane) reduces the size and activity of the sebaceous glands within the skin, which lowers the total amount of sebum that’s generated. This prevents the glands from getting obstructed, and germs are not as likely to flourish. Additionally, it lessens the redness of the skin. Side effects Serious side effects are rare and occur in less than 1 in 1,000 individuals. Stop taking isotretinoin Zenatane capsules and inform a doctor straight away in the Event That You get: Stress, Suicidal ideas – these may be indications of mental health issues Acute pain in your stomach without diarrhea, Violence and aggression, Feeling ill, and Nausea Trouble moving your arms or thighs, and painful, swollen or bruised parts of the body. A Severe skin rash that soothes or has blisters Even darkened urine Yellowish eyes or skin, Difficulty swallowing or feeling quite tired A lousy headache which does not go off and cause you to feel sick or vomit Abrupt changes in vision It is infrequent; however, isotretinoin capsules can occasionally result in sadness or make it worse and also make people feel dizzy. In rare situations, it is likely to have a severe allergic reaction to isotretinoin capsules. Zenatane in Pregnancy Isotretinoin is damaging to the fetus and so shouldn’t be used through pregnancy. Women of childbearing age should have two negative pregnancy evaluation results before treatment is initiated, and a pregnancy test must be run during every month of treatment. Two powerful kinds of birth control have to be utilized throughout treatment. Pregnancy ought to be avoided a month prior to, during, and at least one month after stopping isotretinoin. It’s not known whether isotretinoin is secreted in breast milk, but because of its potentially serious side effects, it Shouldn’t Be utilized by breastfeeding moms. Isotretinoin Interactions Inform your doctor of all of the medications you are taking. This also has over-the-counter and prescription drugs, vitamins and other nutritional supplements (nutritional shakes, protein powders, etc.), herbal remedies and some other recreational and illegal drugs. Speak with Your doctor about the risks and benefits of taking isotretinoin (Zenatane) if you are using Phenytoin, carbamazepine, Corticosteroids, such as prednisone, prednisolone, or triamcinolone and herbal treatments. Do not take isotretinoin (Zenatane) if you are taking tetracycline antibiotics, such as demeclocycline, doxycycline or vitamin A. You need to limit or avoid drinking while taking isotretinoin. Dose for isotretinoin The suggested dose of isotretinoin (Zenatane) is 0.5 to 2 mg per kg of body weight every day. The daily dose generally is administered in 2 divided doses for 15-20 weeks. Isotretinoin should be taken with meals so as to increase its absorption. Explore More Medicine 

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Ethosuximide (Zarontin): Uses, Side Effects, Dosage

Ethosuximide (Zarontin) is a anti-epileptic medicine, also referred to as an anticonvulsant. Ethosuximide can be used to control absence seizures (petit mal) (a sort of seizure where there is a really brief loss of consciousness through which the individual might stare directly forward or blink his eyes and doesn’t reply to other people ). It operates by reducing abnormal electrical activity in your brain. Precautions Prior to taking ethosuximide (Zarontin), tell your health care provider or pharmacist if you’re allergic to methsuximide; even in case you have some allergies. This medicine could contain inactive ingredients, which may lead to allergic reactions or other issues. Speak with your pharmacist for additional information. Before utilizing this medicine , tell your doctor or pharmacist your medical history, especially of: liver disorder, kidney disorder , psychological /mood disease (for instance, melancholy , psychosis). Alcohol will make you dizzy or drowsy. Don’t drive, use machines, or do anything which requires alertness until you are able to get it done safely. Keep away from alcoholic drinks. Speak with your physician if you are using marijuana. Liquid products can contain alcohol or sugar. Caution is advised if you’ve diabetes, alcohol addiction , liver disorder, or some other condition which needs you to limit/avoid these chemicals in your diet plan. Consult your physician or pharmacist about using this product securely. This medicine passes into breast feeding milk, but is not likely to damage a nursing baby . Ask your physician prior to breast feeding -consuming. Ethosuximide In Pregnancy & Lactation If you’re pregnant, your title might be recorded on a pregnancy registry. This is to monitor the results of the pregnancy and to assess any effects of ethosuximide on the infant. Ethosuximide (Zarontin) may pass into breast milk and might harm a nursing baby. Tell your health care provider if you’re breast-feeding a infant. Mechanism The brain and nerves system are composed of many nerve cells that communicate with one another through electrical signals. These signs should be carefully regulated for the brain and nerves to work properly.This increases the threshold of their mind to stimuli that cause seizures and helps stop seizures. Ethosuximide (Zarontin) is largely utilized to deal with absence (petit mal) seizures. Should you suffer from different kinds of seizures too (such as grand mal seizures), ethosuximide has to be utilised in conjunction with other antiepileptic medications. Zarontin Side Effects More frequent side effects The common side effects that can occur with ethosuximide (Zarontin) contain: Stomach Issues Weight-loss Tiredness or fatigue Dizziness or lightheadedness Unsteadiness when walking Headache Hiccups Trouble focusing If those effects are moderate, they might go away in a couple of days or even a few weeks. If they are more severe or do not go away, speak with your physician or pharmacist. Serious unwanted effects Call your health care provider straight away in the event that you’ve got serious unwanted effects. Serious side effects and their symptoms may contain the following: Serious allergic reactions Changes in thinking, mood, or behavior More frequent or worse grand mal seizures Life-threatening blood issues. Systemic lupus erythematosus, an autoimmune disease Suicidal thoughts or activities. Drug Interactions There may be an interaction involving ethosuximide (Zarontin) and some of these: Phenytoin Lamotrigine Primidone Valproic acid If you’re taking one of these drugs, talk with your physician or pharmacist. Based upon Your Precise Conditions, your Physician may want you to: Change among the medications to another, Change how you’re taking one or both of these medications Quit taking one of those drugs.   Dose For treating generalized absence seizures. Oral dose for Infants, Adolescents, and Children > 6 years Originally, 250 mg PO twice per day. May increase dose by 250 mg/day PO in 4–7 day periods, until seizure control is reached, or to a maximum daily dose of 1.5 g. In a few of patients, concentrations around 150 mcg/mL could be required to attain complete seizure control. For Kids 3–6 years: Originally, 15 mg/kg/day PO, given in two divided doses (Max first dose: 250 mg). Boost each 4–7 days; normal maintenance dose is 15–40 mg/kg/day PO, given in two divided doses. The perfect dose for many pediatric patients is 20 mg/kg/day PO.

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Enoxaparin (Clexane): Uses, Side Effects, Doses

Enoxaparin (Brand Name: Clexane) is used to thin blood. It prevents your blood from forming clots. Blood clots are dangerous because they may create serious blockages in your arteries. This may result in a stroke or a heart attack. Clexane is used to reduce blood clots in people that are hospitalized. It might be used if you are too sick to maneuver around or if you are having a heart attack. Enoxaparin might be utilized as part of a combination treatment. As a consequence, that you might want to take it together with different drugs. Follow your doctor’s instructions carefully because you might want to begin or discontinue this medication or another blood thinner at particular times. Additionally, it is utilized to stop blood clots in your home once you have had stomach surgery or even a knee or hip replacement. This medication can also be utilized to deal with present blood clots from the hospital or in home. A blood clot may be treated in the home so long as it’s not on your lungs. Mechanism Enoxaparinbinds to and potentiates antithrombin (a circulating anticoagulant) to make a complex that irreversibly inactivates clotting factor Xa. It’s less action from factor IIa (thrombin) compared to unfractionated heparin (UFH) due to the low molecular weight. Contraindications Clexane is contraindicated in the following conditions Thrombocytopenia associated with a positive in vitro test for anti-platelet antibody in the presence of enoxaparin sodium Active Key bleeding Known hypersensitivity to enoxaparin sodium (e.g., pruritus, urticaria, anaphylactic/anaphylactoid responses ) Known hypersensitivity to heparin or pork products Known hypersensitivity to benzyl alcohol (that can be in just the multi-dose formula of Clexane Clexane In Pregnancy Clexane is currently in Pregnancy Category B, as stated by the FDA, meaning animal studies haven’t revealed evidence of injury to the developing baby but no adequate studies are performed in pregnant women. Black-Box Warning Clexane includes a black-box warning describing its use in patients with spinal or epidural anesthesia or spinal puncture carries an increased risk of bleeding and swelling. This swelling and bleeding can cause long-term or permanent paralysis. If you’re on Clexane  then you’ll have to have blood tests periodically to determine how well it’s functioning. Side effects The common side effects of enoxaparin can comprise: Bleeding Anemia swelling and pain at the site in the skin where you provide the injection Fever Swelling in your legs Serious side effects include Rebound stroke. Bleeding. Rebound blood clots. Drugs Interactions: Drugs that should be avoided include: Ibuprofen Aspirin. Tinzaparin Apixaban Dabigatran etexilate Naproxen Dose for enoxaparin Dose for Preventing deep vein thrombosis following abdominal operation is 40 mg subcutaneous injection once every day. Dose for Preventing deep vein thrombosis following hip replacement: 30 mg every 12 hours or 40 mg once per day by subcutaneous injection. Treatment of deep vein thrombosis or pulmonary embolism: 1 mg/kg each 12 hours or 1.5 mg/kg once per day by subcutaneous injection. Dose for the Treatment of acute heart attacks (ST altitude myocardial infarction or STEMI): For individuals below the age of 75, 30 mg orally and one mg/kg subcutaneously followed by 1 mg/kg every 12 hours (max of 100 mg to each of their initial two subcutaneous doses only). For individuals over age 75, 0.75 mg/kg subcutaneously every 12 hours (max of 75 mg to each of their initial 2 subcutaneous doses only). All patients should get aspirin. Dose For coronary artery stent processes (percutaneous coronary intervention or PCI).Patients must get 0.3 mg/kg through stent placement if the previous dose of Lovenox was administered over 8 hours prior to the procedure. Dose for the Treatment of chest pain (Unstable angina) or moderate heart attack (non-Q-wave myocardial infarction) is 1 mg/kg subcutaneously every 12 hours using aspirin.

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Tranexamic acid (Transamin): Uses, Side Effects, Dosage

Tranexamic acid (Brand: Transamin) prevents enzymes in the human body from breaking down blood clots. Transamin is traditionally used in the treatment of heavy menstrual bleeding. This medicine won’t treat premenstrual syndrome (PMS). It’s usually taken with or without meals three times per day for up to 5 times during monthly menstruation. You should start taking this medicine each month as soon as your period begins. Don’t take tranexamic acid whenever you don’t have a time. Require tranexamic acid at roughly the very same times every day you are supposed to get a dose. Tranexamic acid (Transamin Capsules) are usually taken 3 times each day for a max of 4 times. You begin taking the pills once your period begins. Tranexamic Acid Uses Transamin Capsule can be utilized for the treatment, prevention, control, & improvement of the following ailments, ailments and symptoms: Heavy menstrual bleeding Blood clotting issues Swelling in many different body components Acute reduction of blood Transamin Capsule might also be used for purposes not listed here. Mechanism of Action Tranexamic acid competitively inhibits activation of plasminogen hence decreasing conversion of plasminogen into plasmin (fibrinolysin), an enzyme which degrades fibrin clots, fibrinogen, and other plasma proteins, for example, procoagulant factors V and VIII. Tranexamic acid also directly inhibits plasmin action, but higher doses are needed than are required to cut back plasmin formation. Side effects Tranexamic acid can cause unwanted effects. Tell your doctor if any of these symptoms are severe or don’t go off: Headache Fatigue Sinus pain Spine pain Stomach pain Bone, jointpain or muscle soreness Some side effects may be severe like Infection Rash Itching Trouble swallowing or breathing swelling of the face, tongue, throat, lips, eyes, hands, feet, ankles, or lower legs Hoarseness Changes in eyesight, such as colour vision Chest pain shortness of breath Leg swelling, swelling, tenderness, redness, or heat Contraindications Transamin is contraindicated in the following medical conditions It is contraindicated in case of hypersensitivity and allergic reaction to this drugs or any other excipients. Active thromboembolic disease. Fibrinolytic states following consumption coagulopathy. Severe renal impairment due to danger of accumulation. Tranexamic acid in pregnancy & breast-feeding It’s not understood if tranexamic acid will harm an unborn baby. Tell your doctor if you’re pregnant or intend to become pregnant while using this medicine. Tranexamic acid may pass into breast milk and might harm a nursing baby. Don’t use this medicine without telling your doctor if you’re breast-feeding a infant. Drug interactions Tell your doctor about all other Medications you use, especially: Hormonal birth control (like birth control pills, implants, injections, skin spots, and vaginal rings); Any kind of medication to cure a bleeding event or a blood clot; or factor IX (Bebulin VH, Konyne 80, Profilnine SD, Proplex T, and many others ). Chemotherapy medicine to treat leukemia; Tretinoin It may interact with Acetaminophen, Albuterol, Ascorbic acid, Aspirin, Clopidogrel, Cyclobenzaprine, Diazepam, Diphenhydramine, Epinephrine and Esomeprazole. This is not a complete list of interactions. Consult your GP before using Transamin with other drugs. Tranaxemic acid (Transamin) Dose Oral route: Usual Dose: 1-2 capsules (250 mg) 3 times per day or one tab (500 milligrams ) 3-4 times each day. Menorrhagia (Heavy Menstrual Bleeding): 4 capsules or two tablets (1 g) 3 times each day beginning on the 1st day of the interval for days of heavy stream. Dose for intravenous or intramuscular injection is 2-10 amps (10-50 ml) (500-2500 milligrams ) are awarded by Intravenous drip infusion, if needed. The dose hasn’t been established in pediatric patients. It might be dangerous for the child. It’s always important to completely understand the protection of the medication before using. Please consult with your physician or pharmacist to learn more.

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Gentamicin (Gentalek): Uses, Side Effects, Precautions, Dosage

Gentamicin (Gentalek) is a wide spectrum aminoglycoside antibiotic that’s quite effective against aerobicgram-negative rods. Gentamicin can also be utilized in conjunction with other antibiotics to treat infections brought on by gram positive organisms like Staphylococcus aureus and particular species of streptococci. Furthermore, gentamicin is employed together with a penicillin antibiotic to treat endocarditis(disease of the heart). Precautions Before utilizing gentamicin, tell your health care provider or pharmacist if you’re allergic to it or into other aminoglycoside antibiotics (eg, tobramycin, amikacin); even in case you have any allergies. This could contain inactive ingredients (like sulfites), which may lead to allergic reactions or other issues. Speak with your pharmacist for additional information. Before having surgery, tell your health care provider or dentist about all of the products that you use (such as prescription medications , nonprescription medications, and herbal products). Gentamicin might cause reside bacterial vaccines (for example, typhoid vaccine) not to do the job too. Don’t have some immunizations/vaccinations whilst using this medicine unless your doctor tells you to. Older adults may be more sensitive to the consequences of the medication, particularly kidney harm. How It Work Gentamicin (Gentalek) kills bacteria (bactericidal) by inhibiting the synthesis of bacterial proteins. Gentamicin irreversibly binds to the 30S ribosomal subunits. This binding interferes with the creation of messenger RNA (mRNA) and the subsequent creation of nonfunctional proteins and the eventual death of susceptible bacteria. Gentamicin (Gentalek) Injection Side-effects Listed below are a listing of Common side-effects which might happen from all constituting elements of Gentalek Injection. This isn’t a comprehensive listing. All these side-effects are potential, but don’t necessarily happen. A few of the side-effects could be infrequent but severe. Ask your health care provider if you see any of the subsequent side-effects, particularly if they don’t go away. Nephrotoxicity Inflammation of mouth or lips Vertigo Dizziness Hearing loss Skin tingling Tinnitus Roaring in the ears Muscle twitching Numbness Gentamicin (Gentalek) In Pregnancy & Breast Feeding This medicine isn’t recommended to be used through pregnancy. Though there were reports of injury in babies born to women with comparable medications, the danger of injury might not be exactly the same with this medication. This medication passes into breast feeding milk in tiny quantities. But many physicians consider breastfeeding secure whilst using this medicine. Ask your physician prior to breastfeeding. Interactions Some medications and gentamicin (Gentalek) can interfere with one another. These include: Diuretics such as frusemide; Anticancer drugs like cisplatin; Antibiotics Vitamin K; Any medication that might lead to kidney or hearing problems; Amphotericin, an anti-fungal medicine; Muscle relaxants like suxamethonium. Anaesthetics like halothane; Dose This will be dependent on your age, weight, type of disease as well as how well your kidneys are functioning. On the other hand, the typical adult dose of Gentamicin Injection is 60-80mg daily for 7-10 days. Laboratory tests (for instance, kidney feature, levels of medication from the bloodstream ) can be conducted to help get the ideal dose for your situation. If you’re giving (Gentalek) to yourself in your home, find out all preparation and usage instructions from the healthcare professional. If either is present, don’t use the liquid. Find out how to store and discard medical equipment safely.

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Clarithromycin (Claritek): Uses, Side Effects, Doses

Clarithromycin (Claritek) belongs to a group of drugs known as macrolide. it penetrates lung tissue and macrophages to a larger level than erythromycin; employed for respiratory tract infections, STDs, otitis media, and MAC in AIDS patients; utilized in combination regimens for H. pylori eradication. Researchers from the Japanse drug firm Taisho Pharmaceutical developed clarithromycin from the 1970s. Back in 1985, Taisho partnered with the American firm Abbott Laboratories for its global rights, and Abbott gained FDA approval for Biaxin in October, 1991. The medication went generic in the USA in 2005. Clarithromycin (Claritek) Uses Clarithromycin is often used for Pneumonia, Bronchitis, and Infections of the ears, sinuses, skin and throat. Also used in combination with other medicines to eliminate H. pylori . It is also used to treat and prevent disseminated Mycobacterium avium complex (MAC) infection, which is a type of lung infection that often occurs in patients with HIV. It is occasionally used to prevent heart infections in people having dental or other procedure. It is sometimes used to treat other types of infections including Lyme disease, cryptosporidiosis, cat scratch disease, Legionnaires’ disease, and pertussis (whooping cough). Leprosy Skin infections Mechanism It works by preventing the growth of bacteria. Clarithromycin prevents bacteria by acting as a protein synthesis inhibitor. It binds to 23S rRNA, a Part of the 50S subunit of the bacterial ribosome, thus inhibiting the translation of peptides Like most antibiotics, it can’t kill viruses which cause, influenza or other viral diseases. Side effects Clarithromycin oral pill does not cause drowsiness. But, it may cause other unwanted effects. Common side effects The common side effects of clarithromycin oral pill can comprise: Nausea Vomiting Stomach pain Unnatural taste in your mouth If these impacts are moderate, they might go away in a couple of days or even a few weeks. If they are more severe or do not go away, Speak with your Physician or pharmacist Serious unwanted effects Serious side effects and their symptoms may contain the following: Hypersensitivity reaction or allergic reactions Liver Issues. Symptoms may include: Fatigue, Reduction of desire, upper gut pain, Dark-colored urine, Yellowing of skin or the whites of your eyes Heart rate issues. Call your health care provider straight away in the event that you’ve got serious unwanted effects. Call 911 if your symptoms are feeling harmless or when you feel you are having a health emergency. Clarithromycin (Claritek) in Pregnancy & Breast feeding Safe use of clarithromycin in pregnancy hasn’t yet been established. There are no adequate studies in pregnant women. Clarithromycin is excreted in breast milk. Dose for clarithromycin Clarithromycin can be taken with or without meals. For many infections the recommended adult dose is 250-500 mg of immediate release tablets twice per day or 1000 milligrams of extended release tablets once daily for 7-14 days.

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Ibugesic: Uses, Side Effects, Precautions, Dosage

Ibugesic Tablet contain Ibuprofen as active ingredient. Ibuprofen belongs to a group of medicine known as Non steriodal anti inflammatory Drugs (NSAIDs). It is used to treat pain and inflammations caused by many conditions like Osteoarthritis, Rheumatoid Arthritis. It is also used to treat mild to moderate fever.It is also used in other conditions. (Please Check Below). It is manufactured by Cipla Ltd. Composition Ibugesic Tablet Comes in Two Forms Ibugesic 200MG Ibugesic 400MG Ibugesic Tablet is used in the treatment of the following medical conditions  Fevers  Pain and swelling associated with arthritis  Headaches  Migraines  Sinus pain  Sprains and strains  Backache  Muscular pain  Period pain  Dental pain  Soft Tissue Sport injuries  Pain Caused by Cold and Flu  Neuralgia  Pain due to minor injuries  Cold and flu symptoms. Ibuprofen is a non-selective inhibitor of Cyclooxygenase, an enzyme invovled in prostaglandin synthesis via the arachidonic acid pathway. Its pharmacologic effects are believed to be due to inhibition cyclooxygenase-2 (COX-2) that decreases the synthesis of prostaglandins involved in mediating inflammation, pain, fever and swelling. Common side effects of ibuprofen (Ibugesic Plus)  include: Constipation or diarrhoea Nausea or vomiting Indigestion (dyspepsia) or abdominal pain Heartburn Stomach Ulcers Headache Dizziness Salt and fluid retention High blood pressure Flatulence Loss of appetite Stomach cramps Less common side effects include: Raised blood pressure Headache or dizziness Inflammation of the stomach (gastritis) Bloating (fluid retention) Black stools and blood in your vomit – this can indicate bleeding in your stomach Allergic reactions – such as a rash A stomach ulcer Worsening of asthma symptoms by causing narrowing of the airways (bronchospasm) Kidney failure. Avoid Ibugesic If Are taking alcohol or salicylates to prevent bleeding Avoid using it if allergic to ibuprofen Consult your doctor if you have systemic lupus erythematosus Consult your doctor if you develop blurred vision, ringing or roaring in ears Take the drug with a meal or snack to prevent upset stomach. It is best not to take Ibuprofen as a normal pain reliever during pregnancy.The reason for your caution is that taking ibuprofen regularly may harm your baby. Taking ibuprofen often in the first trimester may increase the likelihood of miscarriage. Your baby may also develop a heart defect or other anomalies, such as cleft palate or abdominal wall defects. Its best to consult your doctor before using Ibugesic in Pregnancy. Take as Directed By your physician. The missed dose can be taken as soon as you remember. However, the missed dose should be skipped if it is almost time for the next dose.Seek emergency medical treatment or contact the doctor in case of overdose.

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