Gentamicin (Gentalek): Uses, Side Effects, Precautions, Dosage

Gentamicin (Gentalek) is a wide spectrum aminoglycoside antibiotic that’s quite effective against aerobicgram-negative rods. Gentamicin can also be utilized in conjunction with other antibiotics to treat infections brought on by gram positive organisms like Staphylococcus aureus and particular species of streptococci. Furthermore, gentamicin is employed together with a penicillin antibiotic to treat endocarditis(disease of the heart).


  • Before utilizing gentamicin, tell your health care provider or pharmacist if you’re allergic to it or into other aminoglycoside antibiotics (eg, tobramycin, amikacin); even in case you have any allergies. This could contain inactive ingredients (like sulfites), which may lead to allergic reactions or other issues. Speak with your pharmacist for additional information.
  • Before having surgery, tell your health care provider or dentist about all of the products that you use (such as prescription medications , nonprescription medications, and herbal products).
  • Gentamicin might cause reside bacterial vaccines (for example, typhoid vaccine) not to do the job too. Don’t have some immunizations/vaccinations whilst using this medicine unless your doctor tells you to.
  • Older adults may be more sensitive to the consequences of the medication, particularly kidney harm.

How It Work

Gentamicin (Gentalek) kills bacteria (bactericidal) by inhibiting the synthesis of bacterial proteins. Gentamicin irreversibly binds to the 30S ribosomal subunits. This binding interferes with the creation of messenger RNA (mRNA) and the subsequent creation of nonfunctional proteins and the eventual death of susceptible bacteria.

Gentamicin (Gentalek) Injection Side-effects

Listed below are a listing of Common side-effects which might happen from all constituting elements of Gentalek Injection. This isn’t a comprehensive listing. All these side-effects are potential, but don’t necessarily happen. A few of the side-effects could be infrequent but severe. Ask your health care provider if you see any of the subsequent side-effects, particularly if they don’t go away.

  • Nephrotoxicity
  • Inflammation of mouth or lips
  • Vertigo
  • Dizziness
  • Hearing loss
  • Skin tingling
  • Tinnitus
  • Roaring in the ears
  • Muscle twitching
  • Numbness

Gentamicin (Gentalek) In Pregnancy & Breast Feeding

This medicine isn’t recommended to be used through pregnancy. Though there were reports of injury in babies born to women with comparable medications, the danger of injury might not be exactly the same with this medication.

This medication passes into breast feeding milk in tiny quantities. But many physicians consider breastfeeding secure whilst using this medicine. Ask your physician prior to breastfeeding.


Some medications and gentamicin (Gentalek) can interfere with one another. These include:

  • Diuretics such as frusemide;
  • Anticancer drugs like cisplatin;
  • Antibiotics
  • Vitamin K;
  • Any medication that might lead to kidney or hearing problems;
  • Amphotericin, an anti-fungal medicine;
  • Muscle relaxants like suxamethonium.
  • Anaesthetics like halothane;


This will be dependent on your age, weight, type of disease as well as how well your kidneys are functioning. On the other hand, the typical adult dose of Gentamicin Injection is 60-80mg daily for 7-10 days.

Laboratory tests (for instance, kidney feature, levels of medication from the bloodstream ) can be conducted to help get the ideal dose for your situation.

If you’re giving (Gentalek) to yourself in your home, find out all preparation and usage instructions from the healthcare professional. If either is present, don’t use the liquid. Find out how to store and discard medical equipment safely.

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