Ethosuximide (Zarontin): Uses, Side Effects, Dosage

Ethosuximide (Zarontin) is a anti-epileptic medicine, also referred to as an anticonvulsant. Ethosuximide can be used to control absence seizures (petit mal) (a sort of seizure where there is a really brief loss of consciousness through which the individual might stare directly forward or blink his eyes and doesn’t reply to other people ). It operates by reducing abnormal electrical activity in your brain.


  • Prior to taking ethosuximide (Zarontin), tell your health care provider or pharmacist if you’re allergic to methsuximide; even in case you have some allergies. This medicine could contain inactive ingredients, which may lead to allergic reactions or other issues. Speak with your pharmacist for additional information.
  • Before utilizing this medicine , tell your doctor or pharmacist your medical history, especially of: liver disorder, kidney disorder , psychological /mood disease (for instance, melancholy , psychosis).
  • Alcohol will make you dizzy or drowsy. Don’t drive, use machines, or do anything which requires alertness until you are able to get it done safely. Keep away from alcoholic drinks. Speak with your physician if you are using marijuana.
  • Liquid products can contain alcohol or sugar. Caution is advised if you’ve diabetes, alcohol addiction , liver disorder, or some other condition which needs you to limit/avoid these chemicals in your diet plan. Consult your physician or pharmacist about using this product securely.
  • This medicine passes into breast feeding milk, but is not likely to damage a nursing baby . Ask your physician prior to breast feeding -consuming.

Ethosuximide In Pregnancy & Lactation

  • If you’re pregnant, your title might be recorded on a pregnancy registry. This is to monitor the results of the pregnancy and to assess any effects of ethosuximide on the infant.
  • Ethosuximide (Zarontin) may pass into breast milk and might harm a nursing baby. Tell your health care provider if you’re breast-feeding a infant.


The brain and nerves system are composed of many nerve cells that communicate with one another through electrical signals. These signs should be carefully regulated for the brain and nerves to work properly.This increases the threshold of their mind to stimuli that cause seizures and helps stop seizures.

Ethosuximide (Zarontin) is largely utilized to deal with absence (petit mal) seizures. Should you suffer from different kinds of seizures too (such as grand mal seizures), ethosuximide has to be utilised in conjunction with other antiepileptic medications.

Zarontin Side Effects

More frequent side effects

The common side effects that can occur with ethosuximide (Zarontin) contain:

  • Stomach Issues
  • Weight-loss
  • Tiredness or fatigue
  • Dizziness or lightheadedness
  • Unsteadiness when walking
  • Headache
  • Hiccups
  • Trouble focusing

If those effects are moderate, they might go away in a couple of days or even a few weeks. If they are more severe or do not go away, speak with your physician or pharmacist.

Serious unwanted effects

Call your health care provider straight away in the event that you’ve got serious unwanted effects. Serious side effects and their symptoms may contain the following:

  • Serious allergic reactions
  • Changes in thinking, mood, or behavior
  • More frequent or worse grand mal seizures
  • Life-threatening blood issues.
  • Systemic lupus erythematosus, an autoimmune disease
  • Suicidal thoughts or activities.

Drug Interactions

There may be an interaction involving ethosuximide (Zarontin) and some of these:

  • Phenytoin
  • Lamotrigine
  • Primidone
  • Valproic acid

If you’re taking one of these drugs, talk with your physician or pharmacist. Based upon Your Precise Conditions, your Physician may want you to:

  • Change among the medications to another,
  • Change how you’re taking one or both of these medications
  • Quit taking one of those drugs.



For treating generalized absence seizures.

  • Oral dose for Infants, Adolescents, and Children > 6 years
    Originally, 250 mg PO twice per day. May increase dose by 250 mg/day PO in 4–7 day periods, until seizure control is reached, or to a maximum daily dose of 1.5 g. In a few of patients, concentrations around 150 mcg/mL could be required to attain complete seizure control.
  • For Kids 3–6 years: Originally, 15 mg/kg/day PO, given in two divided doses (Max first dose: 250 mg). Boost each 4–7 days; normal maintenance dose is 15–40 mg/kg/day PO, given in two divided doses. The perfect dose for many pediatric patients is 20 mg/kg/day PO.

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