Manzoor (Pharm-D)

Medical Conditions & Healing: Throughout the world today, Hydrotherapy, also called Balneo Τherapy or Spa Τherapy or Medical Hydrolology, is a well recognized physiotherapy modality. It is an important component of the holistic approach to healing a wide range of health disorders. It acts adjunctively to medical therapy. In medical hydrology, there are three main ways patients can benefit from hot and/or mineral spring water: 1- Externally, through therapeutic baths (body immersion, either total or partial) 2- Internally, through drinking mineral spring water 3- Through inhalation of steam These three methods used in Spa Therapy have healing effects on various kinds of disorders. Let us see in more detail the diseases that can be treated by each method: a. Therapeutic baths in hot and mineral spring water Rheumatic diseases (arthropathies) 1. Inflammatory rheumatic diseases: • Rheumatoid arthritis • Ankylosic spondylitis • Psoriatic arthritis • Gout and hyperuricemia • Enteropathic arthritis 2. Degenerative rheumatic diseases (result of “wear and tear” of the joints) • Peripheral: Osteoarthritis of the hip, knee, ankle, foot, shoulder, elbow, wrist, hand (with pain, stiffness and functional disorders in the affected joint) • Central: Depending on the part of the spine involved, there is neck pain, low back pain etc Osteoarthritis of the spine Spondyloarthropathies Skin diseases • Eczema • Acme • Dermatitis • Psoriasis • Skin allergies • Neurodermatitis Diseases of the peripheral nerves • Neuritis • Neuralgia • Radiculopathy (nerve root pain) i.e. lumbar nerve pain (often called sciatica), brachial neuralgia (nerve pain in the arm) Cardiovascular diseases • Arterial hypertension • Phlebitis • Varicose veins • Heart valves diseases Gynecological diseases • Chronic after inflammation conditions of the uterus and salpinx • Salpingitis • Trachilitis • Ovarian insufficiency • Leukorrhea Metabolic diseases and disorders of mineral metabolism • Osteoporosis • Obesity Post traumatic and post-surgical disorders • Pain, stiffness and functional disorders (limitation of movement) after fracture • Sprains • Muscle tear • Muscle pull Other diseases and disorders • Chronic fatigue • Fibromyalgia b. Drinking Mineral Spring Water Gastrointestinal diseases (diseases of the alimentary canal) • Chronic Constipation • Dyspepsia (indigestion) • Irritable bowel syndrome • Colitis (disease of the colon) • Chronic cholecystitis • Cholelithiasis and/or Choledocholithiasis (stone of the gallbladder and/or the chelodechus) Diseases of the urinary system • Chronic cystitis • Lithiasis of the urinary tract • Proteinuria Metabolic diseases • Obesity • Toxins elimination Furthermore, salt-rich mineral waters enhance the conversion of cholesterol into bile acids and their subsequent secretion. c. Inhaling Mineral Spring Water Respiratory diseases • Asthma bronchiole • Chronic bronchitis • Chronic rhinitis (nose) • Chronic pharyngitis (throat) • Chronic laryngitis • Allergies

Facts: Name : Alla Ilyinichna Levushkina Age: 89 years Old Height: 4ft 9in Nationality: Russian Total Operations:10,000+ Daily Operations: 4 Daily She is now considered one of the World’s oldest surgeon. She has performed more than 10,000 surgeries in her life But Her Hands are very stable. During part of her time serving as operating surgeon, she flew round the Russian geographical region for thirty years, treating patients living in far-flung areas of the country.A few years back she came back to her town of Ryazan, close to Moscow, and has worked at town Hospital since.And The intresting Thing Is That She Is Single and She Is Living In Apartment With Her Disable Nephew And 8 Cats . However, medicine isn’t invariably wherever she saw her career going – she originally wished to be a geologist, reports Russian newspaper Kommersant. But she was impressed to become a doctor after reading a novel regarding doctors and went on to study at the moscow Medical Institute. Alla Specialty Is In proctology, a field of medicine that deals with bowel and rectal problems. She said: ‘I work and everything. I even have nothing to do in retirement. Doctor – it’s not simply a profession it’s a way of life. Why else would the Dr. live, if not to work?’ I work because it’s fascinating to me, and additionally because i prefer to win. I like to help individuals accomplish remissions.‘There are people I saved a few years ago when no one else wanted to perform an operation on them. and i did that and that they are still alive and have grown up kids.’ Alla is happy with her track record – zero fatalities – and is living her childhood dream.In honour of her loyalty to the profession, Alla was recently awarded the prize for the most effective doctor in Russia.

According To WHO “A Drug May Be Defined As Any Substance Which Is Used Or Intended to Be used For Modifying Or Exploring Physiological System Or Pathological States For the Benefits Of Recipient” So Life Saving Drugs Are Those Drugs Which Save Lives In Case Of Emergency. These Drugs Have The Capability To Hold Life Or Prevent Further Damage And Complications.These Drugs Are Used In Emergency Situation, Intensive Care units, These Drugs Help Patient Close To Life.The List Of Life Saving Drugs Are Not Small But some Of the Agents are Listed Below (1) Drugs Used In Severe Bleeding (a)Vitamin -k (b)Epinephrine (c)Norepinephrine (2)Drugs Used In Hypertensive Emergency (a)Nitric Oxide (3)Drugs Used In Myocardial Infarction (MI) (a)Nifedipine (Capsule) (b)Digoxin (Inj) (c)Isoprenaline (Inj) (d)Calcium Chloride (Inj) (e)Meperidine Hydrochloride (Inj) (f)Heparin (Inj) (g)Nitroglycerine (Inj) (h)Streptokinase (Inj) (i)Propranolol (Inj) (j)Protamine Sulphate (Inj) (k)Dopamine Hydrochloride (Inj) (l)Aminocaproic Acid (Inj) (m)Lignocaine Hydrochloride (4)Drugs Used In Respiratory Failure (a)Oxygen Gas   I.P/B.P (b)Nikenamide (Inj) (5)Drugs Used In Anaphylactic Shock (a)Epinephrine hydrochloride (Adrenaline) (Inj) (b)Dexamethasone Sodium Phosphate (Inj) (c)Sodabicarb (Inj) (6)Drugs Used In status Epilepticus (a)Phenobarbitone (Inj) (b)Phenytoin Sodium (Inj) (c) Carbamazepine (Inj) (7)Drugs Used In Peripheral Circulatory Collapse (a)Oxygen Gas   I.P/B.P (b)Glucose 25% (Inj) (c)Dopamine Hydrochloride (Inj) (d)Normal Saline (I.V) (e)Ringer Solution (I.V) (8)Drugs Used In Treatment Of Hypoglycemia: (In Adult And In Childrens) a)Glucagon (I.M) Or S.C Inj (9)Drug Used In Treatment Of Sever Angina Attack In Adult: (a)Glyceryl Trinitrate  (Sublingual Spray) (10)Drug Used In Pain relief in emergency rescue situations (adults and children): (a)A medical gas mixture of 50% nitrous oxide and 50% oxygen  (Inhalational form) (11)Drugs Used In Treatment of acute asthmatic attack (adults and children): (a)Salbutamol (Inhaler) (12)Antisnake venom inj  polyvalent Injection (13)Rabies vaccine Injection (14)Tetanus Toxoid Injection. Follow Our Blog For More Such Contents And Please Enlist Other Life-Saving Drugs In Comment Section Which Is Missing Here Originally Published In www.thedrugsbank.com

You’re feeling Unwell. You have wheezes, sniffling, and a sore throat. Is it a chilly (Cold), influenza (Flu), or Allergy (sensitivities)? It can be difficult to let them know separated in light of the fact that they share such a variety of symptoms. Be that as it may, understanding the differences will help you pick the best treatment. Cold, influenza (Flu), and Allergy all influence your respiratory framework, which can make it difficult to relax. Every condition has key indications that set them apart. COLD: A cold is a mild viral infection of the nose, throat, sinuses and Respiratory Airways. It’s very common and usually clears up on its own within 7-14 Day. Once a cold Virus gets inside you, your immune System, the body’s safeguard against germs, dispatches a counter-Attack. It’s this reaction that brings on the great side effects like a hack or stuffed up nose. FLU: Flu (otherwise called seasonal influenza) is an infectious respiratory sickness brought on by influenza infections. It can make gentle serious disease, and now and again can prompt to death. This season’s flu virus is not the same as a cold. This season’s flu virus, as a rule, goes ahead abruptly. ALLERGY: It’s an alternate story with hypersensitivities. They’re brought on by an overactive immune System. For reasons unknown, your body mistake safe things, for example, clean or dust, for germs and Attack them. The Most examples Are Hay Fever,Eczema,Allergic Conjunctivitis,(Allergic eyes),Asthma,Hives And Allergic Shock. Kindly Check The Table Below For difference Among Cold ,Flu,And Allergy Signs and Symptoms Cold Flu Allergy Runny,Stuffy Nose Common Sometimes Often Fever Rare Usual, high (100-102 °F), sometimes higher, especially in young children); lasts 3-4 days No Pain Some Times Usual,Some Time Sever No Pain Cough Often Common,Can Become Sever Some Times Sneezing Often Some times Often Weakness Some times Usual,Can Last Upto 20 Days Some Times Head ache Uncommon Common Uncommon Sore Throat Common Some Times Common  

Baclofen is a Prescription Antispastic drug and used to treat muscle spasms caused by certain conditions (such as multiple sclerosis, spinal cord injury/disease). It works by helping to relax the muscles.Baclofen is a gamma-amino-butyric acid (GABA) derivative used as a muscle relaxant. The exact mechanism of action is unknown but It’s thought that baclofen blocks the signals from your nervous system that tell your muscles to spasm. Dosage: For muscle relaxation: Adults and teenagers—At first, the dose is 5 milligrams (mg) 3 times every day. Then, each dose could also be increased by 5 mg every 3 days till the required response is reached. No more than 80 mg ought to be taken within a twenty-four-hour period. Children—Use and dose should be determined by your doctor. Pregnancy: Manufacturer advises use as long as potentiak benefit outweighs risk (Toxicity in animal studies) Baclofen  Side effects: More common side effects The more common side effects of baclofen oral tablet can include: Nausea Headaches Dizziness Drowsiness Constipation Low blood pressure If these effects are mild, they may go away within a few days or a couple of weeks. If they’re more severe or don’t go away, talk to your doctor or pharmacist. Serious side effects Serious side effects and their symptoms can include the following: Feeling very drowsy Trouble urinating Agitation Withdrawal symptoms, such as: Hallucinations Seizures  

108 Millions Blood Donations are collected each year and donation rate are 9 times greater in high-income countries than in Low-income countries. Red Blood Cells Are Constantly replaced as they only Live for average for about 120 days . It takes about 30 seconds for RBC to make a complete circut of your body.In total blood cells take 20 seconds to travel 70,000 miles. A single drop of blood contains about 10,000 white blood cells and 250,000 platelets.Similarly an ounce of blood contains 150 billion Red Blood Cells while in a Pint Of Blood there are about 2.4 trillion blood cells. Our body contains 0.2 milligram of Gold Most of Which is diffused in our blood .It would Take the blood of 40,000 people to make an 8 gram of Gold. 1.3 Million pints of donated blood goes off every year as blood only have 40 days shelf life. During pregnancy to provide blood to the uterus and placenta,a women blood volume increases by 50% .By the end of pregnancy the uterus will receive one fifth of the women’s pre pregnancy blood supply.   A new born has around one cup of blood in its Body.Fo Adults blood counts for around 7% of total body weight and average adult has between 4.7-5 litres of blood in their body. Ever wondered why your nose runs when its Cold.Well it happens as a result of nose receiving increased blood flow to warm up this causes the blood vessel to dilate,which in turn produce more mucous. The reason our viens appears  blue through our skin because of the way different wavelength of light peneterate into our skin are absorbed and relfect to your eyes.human blood is never actually blue. Blood Can come in a variety of shades: Oxygen rich blood is bright red while it turns a darker shade of red once it gives up the oxygen and flow back to the heart. Your Blood Group is identified by the antigens and antibodies the blood contains.Almost half of the population of the UK has the blood group O;This Blood Group doesn’t Contain any antigens but does contain both anti-A and Anti-B Antibodies in the blood. Sources: Telegraph Medical Daily Express    

A Report  launched On Sep-20-2017 by WHO shows a serious lack of New antibiotics under development to combat the growing threat of antimicrobial resistance. Antimicrobial resistance is the ability of microorganism,such as bacteria or viruses,to prevent antibiotics from working against it. This means that standard treatments become ineffective,infections persist and may spread to others. In its report, WHO says that the majority medication presently within the pipeline are modifications of existing classes of antibiotics and are only short solutions. Researchers found few potential treatment choices for antibiotic-resistant infections, together with drug-resistant tuberculosis that kills around 250,000 individuals annually. In addition to multidrug-resistant TB, WHO has identified 12 categories of priority pathogens – some of them inflicting common infections like pneumonia or urinary tract infections – that are progressively resistant to existing antibiotics and desperately in need of new treatments. Dr Tedros Adhanom Ghebreyesus, the director-general of WHO, says that this can be a world emergency. “There is an urgent need for more investment in research and;development for antibiotic-resistant infections including TB,otherwise we will be forced back to a time when people feared common infections and risked their lives from minor surgery.” Dr Suzanne Hill of WHO says that pharmaceutical companies and researchers need to focus on new antibiotics against certain types of extremely serious infections. WHO, along side the drugs for Neglected Diseases Initiative, has launched a partnership to counter the threat. South Africa, Germany and also the uk, among others, have pledged over €56 million for this work. WHO has warned that the new antibiotics won’t be enough to combat the threat of antimicrobial resistance, adding it’ll work with countries and partners to boost infection prevention.

  The effect of drug on a person may be different than expected because that drug interacts with another drug the person is taking (drug-drug interaction), food, beverages, dietary supplements the person is consuming (drug-nutrient/food interaction) or another disease the person has (drug-disease interaction). Some people have greater risk of food and drug interactions who have a poor diet, have serious health problems, children and pregnant women. There are some foods that can interact with drugs by increasing or may be decreasing their actions and are capable of producing some serious side effects. Major side-effects of some diet (food) on drugs include alteration in absorption by fatty, high protein and fiber diets. Bioavailability is an important pharmacokinetic parameter which is correlated with the clinical effect of most drugs. However, in order to evaluate the clinical relevance of a food-drug interaction the impact of food intake on the clinical effect of the drug has to be quantified as well. 1.Bananas Certain Antihypertensive and diuretics can cause undesirable effects when taken with bananas. Foods rich in potassium such as bananas, oranges, green leafy vegetables should not be taken with medicines that increase the levels of potassium in body. Ace inhibitors such as captopril, enalapril, lisinopril used to decrease blood pressure and potassium sparing diuretics are not recommended to take with potassium rich foods. What can happen? Irregular heartbeats and heart palpitations are most likely to occur in patients taking these medicines with bananas. 2. Milk The main component of dairy products is calcium found in milk, yogurt, cheese that can interact with certain antibiotics such as tetracyclines, ciprofloxacin, doxycycline. Tetracycline should be taken one hour before or two hours after meals. What can happen? Tetracyclines can bind calcium and iron, forming insoluble chelates, and influencing its bioavailability. 3. Green vegetables Green leafy vegetables such as kale, spinach, broccoli, cabbage are rich in vitamin K, this vitamin is vital for the production of clotting factors that help prevent bleeding, but anticoagulants like warfarin exert their effect by inhibiting vitamin K. What can happen? An increased intake of the green vegetables can antagonize the anticoagulant effect and prevent the drug from working. 4. Grapefruit Juice Patients should avoid eating grapefruit or drinking grapefruit juice while taking some medications, in particular cholesterol lowering agents such as statins e.g. atorvastatin, lovastatin. Compounds in grapefruit called furanocoumarin chemicals cause an increase in medication potency by interacting with enzymes in the small intestine and liver. What can happen? Drinking grapefruit juice can raise the level of the drug in your bloodstream and increase the risk of side effects, especially muscular weakness and leg pain. 5. Cheesy foods Tyramine-containing food (matured cheese, red vine, ripped bananas, yogurt, soy products and salami) or so-called cheese reaction can cause interactions with monoamine oxidase inhibitors (MAOI) such as Phenelzine, Tranylcypromine that are effective in the treatment of depressive disorders What can happen? If you eat or drink too much of anything that contains the amino acid tyramine, your blood pressure could spike. Headache is the main symptom associated with heart pounding and palpitations and the complications included cardiac arrhythmias, cardiac failure, pulmonary edema, and death. 6. Licorice Licorice contains glycyrrhizin and glycyrrhetinic acid. It causes sodium retention and potassium depletion, so it may interfere with various medicines including antihypertensive and antiarrhythmic agents. What can happen? A high intake of licorice can cause increased blood pressure, edema, hypermineralocorticoidism, and depression of the renin-angiotensin-aldosterone system this. This system is involved in the regulation of systemic blood pressure, renal blood flow, and glomerular filtration rate. 7. Coca-Cola The daily dosage and frequency of NSAID’s like ibuprofen must be reduced when administered with Coca-Cola. Food intake did not appear to affect the extent of absorption of oral Diclofenac potassium soft gelatin capsule at doses. What can happen? There is a significant increase in plasma concentration when ibuprofen is taken with single and multiple doses of Coca-Cola, thereby indicating increased extent of absorption of ibuprofen. By Mahum Zulqarnain Pharm.D University Of Central Punjab Pakistan. References: · Bushra, R., Aslam, N., & Khan, A. Y. (2011). Food-drug interactions. Oman medical journal, 26(2), 77. · Schmidt, L. E., & Dalhoff, K. (2002). Food-drug interactions. Drugs, 62(10), 1481-1502. · Otles, S., & Senturk, A. (2014). Food and drug interactions: a general review. Acta Scientiarum Polonorum Technologia Alimentaria, 13(1), 89-102. · Yeragani, V. K. (2009). Hypertensive crisis and cheese. Indian journal of psychiatry, 51(1), 65-66.