Tru Niagen Review: Does It Work? [2023 Pharmacist’s Advise]

There is a lot of buzz about Tru Niagen (Nicotinamide riboside) and its role in aging, cell repair, and metabolism. That’s why we have decided to inform our readers about the product and the research behind the ingredient in this Tru Niagen Review.

Our bodies naturally age as we go through life. Some of these changes impact our physical and mental capabilities and could make us more susceptible to illness. So, we are all concerned about our fast aging, but no one can actually stop and reverse it.

Researchers think that as you get older, your level of nicotinamide adenine dinucleotide (NAD) naturally falls [1]. This decline can occur if you are exposed to oxidative stress and chronic illnesses, such as diabetes, heart disease, Alzheimer’s disease, and vision loss [2]. 

So, NAD+ is crucial to cells’ normal function, muscle growth, skin elasticity, and organ health and the deficiency of this molecule can lead to cell and tissue damage.

To improve your NAD+ level, you either need to take Nicotinamide riboside or Nicotinamide mononucleotide (NMN) supplements because they both are precursor molecules and can be converted into NAD+ inside the cells.

Anti-aging is now a multi-billion dollar industry, and that’s why different companies offer natural supplements to increase your NAD+ level naturally and safely. Most anti-aging products can be used on the skin; some try to put their potential inside your body. Some claim to improve your human growth hormone (HGH) levels while other promises to boost your NAD. 

Tru Niagen is one such product promised to support your cellular health, safely elevate your NAD+ levels and slow the aging process. The supplement is packed with Nicotinamide Riboside, also known as Niagen, and it works on the inside and helps your body reverse signs of aging.

Why should you trust our reviews?

Our research team checked all the relevant information, facts, and clinical studies about a product, ingredients, and genuine customer feedback.

At DrugsBank, we have now reviewed many health products, including supplements, and over the past five years, we have helped thousands of readers make more informed decisions about the product they are purchasing.  

This Tru Niagen Review, like all other buying guides on this website, is thoroughly evaluated and clinically tested by our panel of pharmacists and Ph.D. scholars. Please note that our reviews are honest, unbiased, and free from marketing tricks.  

Tru Niagen Review (Quick)

Product Full Name: Tru Niagen 300mg

Manufacturer: Chromadex

Best Place To Buy Tru Niagen: Official Company site and Amazon




Evidence For Claims

Amazon Ratings

Total ratings: 2339 (May change with time)

My Honest Tru Niagen Review

In this Tru Niagen Review, we will only discuss Tru Niagen, Its benefits, ingredients, and the recent research about the ingredients, plus we will also tell our readers if it’s really worth the money or another marketing trick. You will also read if it is effective and safe to use or not.  

What is Tru Niagen?

Tru Niagen is a patented anti-aging and metabolism booster, which appears to be promoted primarily for improving cellular energy & repair, metabolism, and maintaining a healthy NAD level. There is limited evidence to support the ingredient in this supplement for its considered use.

Tru Niagen is a NAD (nicotinamide adenine dinucleotide) supplement claimed to help with cell protection, cell repair, and overall healthy aging. The product is specially designed for those looking to increase the body’s nicotinamide adenine dinucleotide (NAD) levels.

The product is manufactured and marketed by ChromDex, a company that is in the field of medicine for the last two decades. Chromadex is one of the leading providers of phytochemical reference standards, botanical reference materials, and research-grade materials for the organic products industry.

The manufacturer of this supplement claims that Tru Niagen may help you slow down the aging process.

So does it work for repairing cellular health and anti-aging purpose, and is it worth the money, or a hoax? Let’s find out in this Tru Niagen Review.

Tru Niagen Ingredient

As discussed earlier, the Tru Niagen is formulated from Nicotinamide Riboside—a molecule similar to vitamin B3 (niacin) and is a precursor for nicotinamide adenine dinucleotide (NAD+). Please note that this form of Vitamin B3 is different from others available on the market. The presence of Nicotinamide Riboside in this supplement helps your body produce nicotinamide adenine dinucleotide (NAD+).

This NAD+ will help you promote healthy cellular energy and repair, plus it will also aid in metabolism. According to some animal studies, a healthy level of NAD+ may also help reverse signs of aging and lower the risk of many other chronic diseases. [3], [4]

In one study, 13 overweight men and women were given 1000 mg of nicotinamide riboside daily for six weeks. After six weeks, the participants increased the metabolism of acetylcarnitine (used for fatty acid metabolism). So, Nicotinamide riboside can also be effective in improving metabolism.

In another study by patent owners, Chromadex uses a placebo and a daily dose of 100 mg, 300 mg, or 1,000 mg of niacin for eight weeks. The study found that blood NAD + levels increased with niacin supplementation, and NAD + metabolism increased significantly in the 300-mg and 1,000-mg groups compared to the placebo.

Is There Any Room For Improvement In Tru Niagen Formulation?

Tru Niagen has been praised for its safe and effective formula, but there may be room for improvement as scientific research progresses. Recent studies and prominent scientists, such as David Sinclair of Harvard, have suggested that NMN may be a superior alternative to NR.

NMN is further down the NAD+ production pathway and more closely resembles NAD+ on a molecular level than NR. This may lead to greater effectiveness in combating aging mechanisms. In fact, studies have shown impressive results with NMN in these areas.

Given this information, adding NMN to Tru Niagen’s formula may be worth considering instead of NR. This change could result in a more powerful and comprehensive formulation addressing a wider range of aging mechanisms. By continually evaluating and improving its product, Tru Niagen can ensure they provide the best solution for its customers’ needs.

How Does It Work?

Like Nicotinamide mononucleotide (NMN)Nicotinamide riboside (NR) is also a precursor molecule and is easily converted to NAD+ in the body. After the conversion, this molecule activates certain enzymes that may promote healthy aging.

The product may also help protect your brain from oxidative stress because NAD+ controls a protein that allows defending cells against oxidative stress and mitochondrial damage[5]. Scientists believe that oxidative stress is primarily responsible for age-related brain illnesses such as Alzheimer’s and Parkinson’s.

Other than these two, the Nicotinamide riboside can also help lower heart-related problems[6], lower cancer risk[7], manage a healthy weight[8], and promote healthy muscle aging [9].

The product work in different ways;

  • It may help promote the repairing of damaged cells in your body.
  • This supplement also maintains a healthy level of cells that develop resistance against normal aging.
  • It may also deal with the daily stress supported by the modern fast lifestyle.

Pros and cons of Tru Niagen

What Do I Like About It?

  • The ingredient (nicotinamide riboside) present in Tru Niagen is clinically proven to increase NAD+ levels and improve mitochondrial health.

  • It is relatively safe to use as FDA has tested it for safety and purity.

  • Tru Niagen is available in 2 different forms: capsules and sticks. This allows users to select the best option that suits them.

  • It is free from gluten, nuts, caffeine, and artificial colors or flavors. No need to worry about allergies.

  • Tru Niagen is a third-party tested and NSF Certified product. Very few companies allow independent third-party laboratories to test their products.

  • Tru Niagen offers free shipping to US customers, so it is a good sign to save a good amount that can be wasted on delivery charges.
What I Don't Like About It?

  • The company doesn’t offer any money-back guarantee and has a strict return policy.

  • The supplement is also expensive compared to other such products.

  • You will need to purchase it in bulk and with an auto-renewal policy if you want a discount.

How to take it—Tru Niagen Dosage?

The product comes in different forms, but each capsule of Tru Niagen will provide the same amount of Nicotinamide riboside.

You will need to take one capsule per day if it’s a 300mg pill, and if it is 150mg, the manufacturer recommends 2 Tru Niagen capsules per day. 300 mg per day is effective and safe in raising the NAD level. 

  • Avoid overdose as it may cause some unexpected side effects.
  • 230mg/day of Nicotinamide riboside is considered safe for pregnant women.[10]

Tru Niagen Side Effects

This product is generally considered safe with no to very few side effects. In some studies, up to 2000mg per day had not shown any adverse effects. But one clinical study noted that the product could cause few low-intensity side effects.

Here is a list of some of the most commonly occurring Tru Niagen Side Effects;

  • Nausea,
  • Stomach upset
  • Muscle pain and soreness,
  • Sore back,
  • High blood pressure,
  • Rashes,
  • Elevated liver function tests.
  • Fatigue,
  • Dyspepsia (pain in the upper abdomen),
  • Diarrhea, and
  • Headache.

Overall, Tru Niagen is considered safe, and in most cases, it will not cause any side effects. However, to be on the safe side, you should follow your doctor’s instructions.

Also, some studies suggest that 230mg of NR is safe in pregnancy, but still, we recommend avoiding it if you are pregnant because it is still unclear if it is 100% safe or not.

Is Tru Niagen legit?

Definitely not. Tru Niagen’s manufacturer, ChromaDex, is a trusted nutraceutical company focusing on developing products to improve aging. Their flagship supplement, Niagen, has been the subject of numerous studies conducted with universities and researchers better to understand the role of NAD in the body.

ChromaDex’s scientific advisory board includes distinguished scientists, including two Nobel Prize winners in Chemistry and experts in Alzheimer’s, breast cancer research, and nutrition. Their participation and advice speak to the scientific community’s high interest and seriousness regarding NR supplementation and research to improve well-being.

Tru Niagen holds over 20 licensed patents and collaborations with over a hundred studies of NR and NAD. So far, five clinical studies have been published, demonstrating the company’s commitment to validating its product and conducting rigorous research.

What is the price and where to buy Tru Niagen?

Tru-Niagen provides customers with various dosage options, including capsules and stick packs, to reach the recommended 300mg/day dosage. Customers can also opt for Tru Niagen Pro, containing 500mg of NR per capsule, available through healthcare practitioners. Recurring shipments can save customers 15-30%, with the option to schedule shipments every 1-6 months, providing flexibility and personalization. Here is how it looks;

Tru Niagen 150mg Capsules

  • The price of a 150mg 120 pills pack: is $87.95
  • The price of 150mg 120-count with the subscription: is $79
  • The average cost of one month’s supply for 30 counts is $47
  • If you buy three months’ supplies, you will need to pay $119.95. ($141)
  • If you buy six months’ supply, you will need to pay $229.95. ($282)

If you look at the price of the Tru Niagen Stick pack, you will see that it is slightly expensive. The original price for one box containing 30 sticks was $54.

Tru Niagen 300mg

The pricing for Tru Niagen’s 300mg capsules varies based on the quantity purchased, as well as whether the purchase is made as a one-time purchase or on a subscription basis.

Price For Subscribers

One Time Purchasers

30 Capsules



90 Capsules



180 Capsules



Tru Niagen Stick packs

Tru Niagen’s stick pack contains 30 separately packaged powder sticks that provide the recommended 300mg dose of NR when mixed with a beverage and consumed once a day. Additionally, the sticks include healthy insoluble fiber from chicory root extract, making it a convenient option for individuals who prefer not to consume pills. While stick packs are the most expensive Tru Niagen product, they are an excellent alternative for those seeking a different delivery method. Here is the breakdown of their prices;

  • The average price for a 30count one-time purchase: is $54
  • The average price for a 30-count subscription purchase: is $49.95

These products are available on the company’s official site, Amazon, eBay, Whole Foods Walmart, etc. The best place to buy Tru Niagen is its official site.

I’m not too fond of this product because they don’t provide any money-back guarantee, and they only refund those with a factory seal bottle, and that too in 30 days from the date of purchase.

Does Tru Niagen work?

Some clinical studies suggest that Nicotinamide riboside present in Tru Niagen is beneficial for health. However, researchers are still working to prove its health benefits.

The FDA has also tested the ingredient, and according to them, it is a safe supplement if taken as directed by the manufacturer and health care providers.

Nicotinamide riboside increases levels of NAD +, which has been linked to potential health benefits in terms of aging, mental health, risk of heart disease, and more.

Overall, if you look at the research studies, you will find that healthy levels of NAD can have a vital role in your metabolism, cellular health, DNA repair, etc.

So, If you don’t mind paying a dollar per day for this product and are comfortable with the available clinical studies, we recommend you try it. Also, as we all know, it is a supplement and not an approved drug, so you will need to give it some time to see its effects.

Tru Niagen Review

What Other People think about it—Tru Niagen Reviews?

If you look at the actual customer Tru Niagen reviews, you will find that the product has 4.2/5 star ratings on Amazon, which shows a positive image.

Let’s have a look at some of the positive and negative Tru Niagen Reviews.

Positive Tru Niagen Reviews

  • According to a customer who is also a physician—Tru Niagen has disappeared his solar lentigo and completely faded after six weeks of use.
  • Another honest Tru Niagen review shows that he takes up to 1 gram a day as per clinical studies, and no adverse effects were reported; instead, he observed good hair, nail, and skin growth with improved brain scores and less delayed onset muscle soreness.

Negative Tru Niagen Reviews

  • For some people, the product can cause severe allergic reactions.
  • One customer thinks they don’t provide a certificate of analysis on request, which is not a GMP standard.
  • Another customer complains that the product contains a chemical that might cause cancer.

Overall, if you look at the customer feedback, you will see more positive reviews than negative ones, which is enough for any potential buyer to opt for. You can also see some of the Tru Niagen before and after images on Amazon and Walmart.

Tru Niagen Alternatives

Supplements containing Nicotinamide ribosides available on the market have the same prices. Some of the products contain a different form of niacin, also known as nicotinamide mononucleotide, which is considerably cheaper.

Here is a list of some of the best Tru Niagen alternatives;

  1. HPN Supplements NAD3 NAD+  Booster: This dietary supplement contains a blend of nicotinamide riboside (NR) and trans-resveratrol, which are both known to increase levels of nicotinamide adenine dinucleotide (NAD+). It is marketed to support healthy aging, cognitive function, and energy levels.
  2. GenF20 NMN: This is a dietary supplement that contains nicotinamide mononucleotide (NMN), which is another precursor to NAD+. In preclinical studies, NMN has been shown to increase NAD+ levels and improve various health outcomes, including metabolic health and lifespan. I personally recommend this one because NMN work well when compared to NR supplements. 
  3. ProHealth NAD+ Pro: This is a dietary supplement that contains a combination of NR, NMN, and other NAD+ precursors, as well as antioxidants and other supportive ingredients. It is marketed to support cellular health, energy metabolism, and cognitive function.
  4. UltraHealth Boost Your NAD+: This is a dietary supplement that contains NR, as well as other supportive ingredients like resveratrol and quercetin. It is marketed to boost NAD+ levels and supports overall health and wellness, including energy metabolism, cognitive function, and healthy aging.

It’s important to note that while these products may have similar ingredients and health claims to Tru Niagen, their safety, and effectiveness may vary, and it’s always recommended to consult with a healthcare professional before taking any new dietary supplement.

What sets Tru Niagen Apart From Its Competitors?

Tru Niagen stands out from its competitors in several ways. Firstly, clinical studies have demonstrated its effectiveness in increasing NAD levels. Additionally, the FDA has deemed Tru Niagen safe for consumption, with no severe side effects reported.

The company’s advisory board includes two Nobel Prize winners, further highlighting the product’s credibility. In terms of affordability, Tru Niagen is priced competitively compared to many other supplements on the market.

Furthermore, the product is available in a convenient powder mix form. Tru Niagen is also free of allergens such as nuts and gluten. It does not contain caffeine, animal by-products, artificial colors, or flavors, making it a suitable option for many individuals.

Frequently Asked Questions (FAQs)

Q. Is Tru Niagen FDA-approved?

Tru Niagen is a dietary supplement and, as such, is not required to be FDA-approved. However, it is manufactured in a facility that follows current Good Manufacturing Practices (cGMP) regulations enforced by the FDA.

Q. Is Tru Niagen good for health?

Tru Niagen contains nicotinamide riboside (NR), shown in preclinical studies to increase levels of a vital molecule called nicotinamide adenine dinucleotide (NAD+) in cells. NAD+ is essential for many cellular processes, including energy production, DNA repair, and gene expression regulation. Although research on Tru Niagen is still in its early stages, some studies suggest it may benefit metabolic health, cognitive function, and aging-related health issues.

Q. Is Tru Niagen the same as vitamin B3?

Yes, Tru Niagen is a form of vitamin B3 called nicotinamide riboside (NR). Like other forms of vitamin B3, such as niacin, NR is converted by the body into nicotinamide adenine dinucleotide (NAD+), a coenzyme that is essential for many cellular processes, including energy production, DNA repair, and gene expression regulation.

Q. How long does Tru Niagen take to work?

The effects of Tru Niagen may vary from person to person, and there is no specific timeline for how long it takes to work. Some people may notice improvements in their energy levels or cognitive function within a few days or weeks, while others may not notice any changes for several months. It’s essential to note that Tru Niagen is not a quick fix, and it may take some time to see significant improvements in health outcomes.

Q. What is the best time to take Tru Niagen?

Tru Niagen can be taken at any time of the day, either in the morning or at night, with or without food. It is recommended to take Tru Niagen at the same time every day to establish a consistent routine. Ultimately, the best time to take Tru Niagen may vary based on personal preference and individual factors.

Q. Is Niagen safe to take?

Based on our research and customer feedback, Niagen is considered safe for adults when taken as recommended. Since its marketing, Niagen has undergone clinical studies, multiple certifications, regulatory approvals, and scientific standards that validate its safety. However, as with any dietary supplement, it is important to follow the recommended dosage and consult a healthcare professional before taking Niagen, especially if you have any underlying health conditions or are taking medication.

Verdict—Tru Niagen Reveiw

So, ladies and gentlemen, we think the product has the potential to improve your NAD+ levels, plus it may improve your skin tone and overall metabolism. The product has the potential to slow down some of the factors responsible for the aging process. 

The company (Chromadex) is not accredited by the better business bureau (BBB), and there are no customer complaints about the product on the BBB official site. 

Other than this, Tru Niagen is made without gluten, animal by-products, and caffeine. Also, Tru Niagen is keto-friendly and can promote cellular repair and increase metabolism.

So, if you are serious about your fast aging and want to improve your level of NAD+ and slow down your aging process, we recommend you try it. 

Or else, we also recommend a natural supplement that can naturally increase your human growth hormone level through organic ingredients.

Yes, we are talking about GenF20 Plus.

  • This supplement can increase your growth hormone, which is also known as the fountain of youth.
  • The product also comes with 2+ months money-back guarantee. 
  • The product is also made from all-natural and proven ingredients. 
  • You can read more about GenF20 Plus ←Here.

Read our list of the top 3 best NAD+ Boosters and more longevity supplements.


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Tru Niagen is designed and manufactured by chromadexu2014a company known for high quality supplements and medicines. The core ingredient used in this supplement is backed by many clinical studies.

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