Montelukast is a leukotriene receptor antagonist (LTRA) used for the maintenance treatment of bronchial asthma, to alleviate symptoms of seasonal allergies and stop exercise-induced breathing issues. it’s typically administered orally.
- Leukotrienes are the mediators of inflammation and are formed by the effect of lipoxygenase enzyme on the arachidonic acid.Leukotrienes are synthesized by eosinophils, Basophils, Mast Cells and macrophages.They Can Cause Bronchoconstriction, Oedema Of bronchial mucous membrane and increased mucous secretion.
- Montelukast is commonly used as a leukotriene receptor antagonist.They Block the receptors for Leukotriene D4(LD4 Receptors).
- The more common side effects which will occur with use of montelukast include: upper respiratory infection (infection within the nose or throat), fever, headache, sore throat, cough, stomach pain, diarrhea, earache or ear infection, flu, runny nose, sinus infection, urinary incontinence in kids whereas Serious side effects and their symptoms will include the following: Behavior and mood changes, Increase in eosinophils (white blood cells), systemic vasculitis (inflamed blood vessels), exaggerated bleeding. Stevens-Johnson syndrome, Uncontrolled muscle movements.
- Take montelukast once a day, in the evening. The dose for adults is one 10 mg pill. If montelukast has been prescribed for your kid, the dose will rely on their age: it’s 4 mg for youngsters aged between 6 months and 6 years, and 5 mg for kids aged between 6 and 15 years.
- The 10 mg (adult) pill will be swallowed with a drink of water and might be taken either before or after food.
- They are especially useful in children, due to their oral administration.Montelukast can be used in children of 6 years or more in age.
- It is pregnancy Category B Drug and there are limited human data accessible. it’s most likely compatible.
- If you’re thinking that there has been an overdose, call your poison center or get medical aid promptly. Be ready to tell or show what was taken, how much, and once it happened.
- Store at room temperature off from light and moisture. don’t store within the bathroom. Keep all medications away from kids and pets.