Cefspan: Uses, Side Effects, Dosage And FAQs

Cefspan (Generic: Cefixime) is a broad spectrum antibiotic manufactured by GlaxoSmithKline Pharmaceuticals Ltd.

Cefspan is a prescription medication used to treat a variety of conditions, including urinary tract infections, throat infections, and bacterial lung infections. This medicine is not recommended for the treatment of colds, flu or other viral infections, as it is effective against infections caused only by certain types of bacteria.

Cefspan come in various form and strengths

  • Cefspan 200 mg Capsule
  • Cefspan 400 mg
  • Cefspan 100 mg Syrup

Cefspan Uses

Cefixime (Cefspan) is effective for infections like:

  • Infection of the middle ear
  • Laryngitis,
  • Pneumonia caused by susceptible bacteria.
  • Tonsillitis,
  • Throat infections and
  • Bronchitis.

Other Uses are

  • Urinary tract infections,
  • Acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD) and
  • Gonorrhea.


Cefspan is administered orally and is in the form of a tablet or liquid, which is given once or twice a day for five to fourteen days.

The usual recommended adult dose for the treatment of tonsillitis, otitis media, pharyngitis, and urinary tract infections is 400 mg once a day or divided at a dose of 200 mg every 12 months. For pediatric patients (6 months or more), a daily dose of 8 mg/kg/ day or two doses of 4 mg/kg/ 12 hours is recommended.

After completing a series of tests, the doctor will know what amount and duration of treatment are appropriate for you. Do not change treatment with Cefspan without medical advice.


Before taking Cefspan, you must discuss with your doctor about your

  • Past medical history
  • If you are allergic to this drug or other medicines in cephalosporin class.
  • If you are Allergic to food or chemicals.
  • Prescription and non-prescription medicines that you are currently using as well as your overall health.

Side Effects

Cefspan can cause certain side effects too. Some common side effects are

  • Nausea,
  • Diarrhea,
  • Stomach pain,
  • Gas,
  • Heartburn, and
  • Vomiting.

These side effects are reversible. But if these symptoms are severe, you should not ignore to take medical help.

Serious side effects

The side effects which could be serious include

  • Difficulty in breathing,
  • Rash,
  • Itching,
  • Stomach cramps,
  • Hives,
  • Swelling of face,
  • Wheezing,
  • Tongue throat, etc.


Like other cephalosporins, Cefixime prevents the proliferation of bacteria by preventing bacteria from forming the surrounding walls. The walls are necessary to protect bacteria from their environment and to hold together the contents of the bacterial cell; Most bacteria can not survive without a cell wall. It fights bacteria in your body.

Frequently Asked Questions

1. Is it Safe with alcohol?

The interactions with alcohol are unknown. Ask your doctor before taking this medicine.

2. Is it habit-forming medicine?

No trend has been reported which constitutes habits.

3. Is cefspan (cefixime) safe during pregnancy?

Animal studies have shown no adverse effects on the fetus, but studies in pregnant women have been insufficient or the effects on the animal have shown adverse effects, but adequate studies in pregnant women showed no risk to the fetus.

4. Is cefspan (cefixime) safe while breastfeeding?

Adequate studies have not been conducted in women to determine the risk of a child becoming pregnant while breastfeeding. Weigh the benefits and potential risks before taking this medicine while breastfeeding.

5. Which medicines or supplements interact with cefspan (cefixime)?

Cefspan may interact with other medicines and cause side effects. Such as

  • Probenecid can increase the blood concentration of cefixime by reducing the elimination of cefixime by the kidneys.
  • The combination of cefixime with aminoglycosides such as tobramycin leads to additive effects of bacterial destruction, but it can also increase the risk of side effects on the kidneys.
  • Exenatide may delay or reduce the absorption of cephalosporins. Cephalosporins should be administered one hour before exenatide.
  • Cefixime may cause live bacterial vaccines (such as typhoid vaccine) to not work as well. Do not be vaccinated while using this medicine, unless your doctor has asked you to do so.
  • Do not use antidiarrheal drugs unless your doctor has asked you to do so.

6 What happens if you miss a dose?

Take the missed dose as soon as you remember. Skip the missed dose when it’s almost time for your next scheduled dose. Do not take other medicines to make up for a forgotten dose.

7. What happens with an overdose?

If an overdose has occurred in a person and severe symptoms such as loss of consciousness or shortness of breath occur, call 911. Otherwise, call a poison control center immediately.

8. What should I avoid when I take this medicine?

Antibiotics can cause diarrhea, which can be a sign of a new infection. If you have watery or bloody diarrhea, talk to your doctor. Do not use antidiarrheal drugs unless your doctor has asked you to do so.

9. How to store cefixime (cefspan)?

Keep out of reach of children. Ask your doctor or pharmacist how to remove the medicines you are not using. Do not store any old or unnecessary medication. Store the medicine in a closed container at room temperature and away from heat, moisture, and direct light.  Store the oral fluid at room temperature or in the refrigerator. Discard unused drugs after 14 days. Keep it tightly closed.

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