Ketoprofen (Profenid Tablet): Uses, Side Effects, Dosage etc

Profenid tablet contain an active ingredient known as Ketoprofen. It belong to a group of drugs called Non Steroidal Anti-inflammatory Drugs (NSAIDs).

It is used for rheumatoid arthritis, osteoarthritis, tooth extraction pain, Acute gout, Inflammation in backbone and spinal, painful menstruation, inflammation after soft tissue injuries, swollen joints,and other conditions.

Profenid Tablet is manufactured by Sanofi Aventis.

Mechanism Of Action

Ketoprofen (Profenid tablet) is used for its antipyretic, analgesic and anti-inflammatory properties by cyclooxygenase-1 and -2 (COX-1 and COX-2) Enzymes reversibly inhibits, which reduces the production of pro-inflammatory prostaglandin precursors. This results in a decrease in prostaglandin levels that mediates pain, fever and inflammation.

Profenid Tablet Uses

Ketoprofen is used in the Treatment, Prevention and Control of the following symptoms and diseases.

  • Profenid tablet is used to relieve pain from various conditions.
  • It also reduces pain, swelling, and joint stiffness from arthritis.
  • This medication is a nonsteroidal anti-inflammatory drug (NSAID). It works by blocking your body’s production of certain natural substances that cause inflammation. This effect helps to decrease swelling, pain, or fever.
  • Tooth extraction pain.
  • Acute gout.
  • Inflammation in backbone.
  • Rheumatoid arthritis.
  • Osteoarthritis.
  • Inflammation in spinal.
  • Painful menstruation.
  • Used in musculoskeletal disorder such as low back pain, sciatica, bursitis, synovitis, tendinitis and fibrositis.

Note: Ketoprofen (Profenid)  may also be used for purposes not listed in this medication guide.

Profenid tablet (Ketoprofen) Side Effects

The more common side effects that can occur with ketoprofen include:

  • Nausea
  • Diarrhea
  • Stomach upset
  • Drowsiness
  • Headache
  • Dizziness

Serious side effects and their symptoms can include the following:

  • Heart attack or stroke.
  • Kidney damage
  • Heart failure.
  • Stomach problems, such as ulcers or bleeding.
  • Liver problems.
  • Skin reactions.
  • Allergic reactions.
Black Box Warning:
Non-steroidal anti-inflammatory drugs (including ketoprofen) may rarely increase the risk of heart attack or stroke. The risk may be higher if you have heart disease or an increased risk of heart disease (for example due to smoking, heart disease in the family or conditions such as high blood pressure or diabetes) or prolonged use. This medicine should not be taken immediately before or after cardiac bypass surgery (CABG). Ask your doctor about the benefits and risks of taking this medicine. Occasionally, this drug can cause severe (rarely fatal) bleeding in the stomach or intestine. This effect can occur without warning at any time while taking this medicine. Older adults may be at greater risk for this effect.


Profenid Tablet is a contraindicated in case of Hypersensitivity. In addition, Profenid Tablet should not be used if you have the following conditions:
  • Gastrointestinal bleeding
  • Active peptic ulcer
  • Alcohol
  • Breastfeeding.

Interaction With Other Drugs

Profenid Tablet may interact with the following drugs and products:

This can increase the risk of side effects or can make your medication not work properly. Tell your doctor about all the medicines, vitamins, and herbal supplements you use to help your doctor prevent or control drug interactions.

Profenid tablet in pregnancy

Taking ketoprofen (Profenid) during the last 3 months of pregnancy can harm the unborn baby. Do not use this medicine without medical advice if you are pregnant.

Profenid in Breastfeeding 

It is not known if ketoprofen passes into breast milk or if it could harm a baby. Do not use this medicine without medical advice if you are breast-feeding a baby.

Profenid Tablet Dosage

The recommended initial dose is 100 to 200 mg per day, which is taken regularly throughout the day in unit doses of 50 mg with food.

It is important that you use the lowest dose that relieves pain. Ketoprofen should not be taken longer than necessary to control the symptoms.

Frequently Asked Questions

1. What are the uses of Profenid? 

Profenid contain ketoprofen which is NSAID and is used for Rheumatoid arthritis, Osteoarthritis, tooth extraction pain, Acute gout, Inflammation in backbone, Inflammation in spinal, Painful menstruation, Inflammation after soft tissue injuries,Swollen joints,and other conditions.

2. What are the side effects of Profenid? 

Side effects associated with the use of this medicine are Nausea, Diarrhea, Stomach upset, Drowsiness, Headache, Dizziness. For more check above.

3. Is Profenid safe in Pregnancy? 

Consult your doctor before using this medicine as it can harm your baby. It is contraindicated especially in the third trimester of pregnancy.

4. Is Profenid safe while Breastfeeding? 

It is unknown if ketoprofen passes into breast milk or if it could harm a baby. Do not use this medicine without medical advice if you are breast-feeding a baby.

5. How long does it take for profenid to work?

It takes 30 minutes to show it’s effect while last for up to 6 hours after taking a ketoprofen dose. However, if your condition has not improved after taking ketoprofen, you should call your doctor.

6. Can you overdose on profenid?

A slight overdose of ketoprofen usually does not cause serious problems. The person may have abdominal pain and vomiting. A large overdose can cause serious harm to children and adults.

In case of an emergency or overdose, call local emergency services or go to the nearest emergency department.

7. What should I do if I miss a dose?

If you miss a dose of Profenid, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and take your usual dose as planned. Do not take a double dose.

8. How should I take profenid?

Take it orally. It can be taken with food because of the stomach upset. If you have persistent abdominal pain, talk to your doctor or pharmacist.

9. How do I store Profenid?

Profenid is best kept at room temperature in relation to direct light and humidity. To avoid damaging drugs.

Do not store it in the bathroom or in the freezer. For your safety, keep all medicines out of the reach of children and pets.

You should not throw it in the toilet or pour it into a sewer unless you are asked to do so. It is important to dispose of this product properly when it is out of date or no longer needed. Contact your pharmacist for more information on safely disposing of the product.

10. Does the food or alcohol work with Profenid?

It may interact with food or alcohol by altering the mode of action of the drug or increasing the risk of serious side effects. Talk to your doctor or pharmacist about possible interactions with food or alcohol before using this medication.

11. What is the dose of Profenid for a child?

The dosage has not been established in children under 15 years of age. This can be dangerous for your child. It is always important to understand the safety of the drug before using it. Contact your doctor or pharmacist for more information.

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2 thoughts on “Ketoprofen (Profenid Tablet): Uses, Side Effects, Dosage etc”

  1. Suresh nepali

    Really it was helpful for me….

  2. Dr ahmed rashid

    Thank you for this information

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