Diphenhydramine: Important Information

Diphenhydramine is an over-the-counter medication that reduces the consequences of natural chemical histamine in the body. histamine will produce symptoms of itching, sneezing, watery eyes, and runny nose. 

  • Diphenhydramine competes with free histamine for binding at HA-receptor sites. This antagonizes the results of histamine on HA-receptors, resulting in a reduction of the negative symptoms brought on by histamine HA-receptor binding. 
  • Common side effects may include: Dry mouth, Dizziness, Headache, Tightness within the chest, Constipation, Drowsiness, Dry nose and throat, Nausea, Feeling edgy (especially in children), Weakness, Loss of appetency while antihistamine will have some serious side effects like Trouble passing pee, change in vision, trouble breathing.
  • Diphenhydramine causes dizziness and drowsiness. don’t drive, use machinery, or do something that wants mental alertness till you recognize how this drug affects you. don’t stand or sit up quickly, particularly if you’re an older patient. This reduces the danger of dizzy or fainting spells. Alcohol could interfere with the effect of this medication. Avoid alcoholic drinks. 
  • Before taking diphenhydramine, tell your doctor or pharmacist if you’re allergic to it, or to dimenhydrinate; or if you have got any other allergies. additionally Before using this medication, tell your doctor or health care provider your medical history, particularly of: breathing problems (such as asthma, emphysema),heart problems,high pressure in the eye(glaucoma), high blood pressure, seizures, stomach/intestine issues (such as ulcers, blockage),liver disease, overactive thyroid(hyperthyroidism), issue urinating (for example, due to enlarged prostate). 
  • A common regimen for treating adult allergic reaction is 25-50 mg each 4-6 hours to not exceed 300 mg daily.When used to treat insomnia, it’s prescribed at bedtime. people over the age of 60 years are particularly sensitive to the sedating and anticholinergic effects of diphenhydramine, and therefore the dose ought to be reduced.Insomnia is treated with fifty mg taken a half-hour before bedtime. 
  • It is a US FDA category B Drug. Diphenhydramine isn’t expected to cause damage to mothers or babies throughout pregnancy – however, this is often not best-known obviously. like any drug, until any studies are done, use diphenhydramine throughout pregnancy given that it is necessary and you have got no alternatives. 

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