Amlodipine: Uses, Side Effects, dosage

Amlodipine is a well-known calcium channel blocker with a range of applications. This article provides an in-depth look at its uses, potential side effects, dosage recommendations, and more.

I. Introduction to Amlodipine

Amlodipine is a calcium channel blocker that plays a pivotal role in managing high blood pressure (hypertension). It possesses the ability to prevent heart diseases, heart attacks, strokes, and is also utilized to alleviate angina-related pain.

II. Pregnancy and Nursing Considerations

While Amlodipine serves as a valuable medication, its usage during pregnancy, lactation, and among children requires careful consideration. This section delves into the existing knowledge and precautions surrounding these scenarios.

III. Mechanism of Action

Understanding how Amlodipine functions is crucial. This section explains how Amlodipine blocks calcium entry into specific tissues and arteries, facilitating better blood flow and reducing blood pressure. Additionally, it explores its impact on heart attack and stroke prevention, as well as chest pain management.

IV. Side Effects

A detailed examination of the side effects associated with Amlodipine is essential for informed use. Here, we categorize common and serious side effects, shedding light on their frequency and severity.

Common Side Effects:

  • Headache
  • Dizziness
  • Flushing
  • Pounding heartbeat
  • Swollen ankles

Serious Side Effects:

  • Stomach issues
  • Yellowing of the skin or eyes
  • Chest pain

V. Recommended Dosages

This section outlines the recommended dosages of Amlodipine for various medical conditions and age groups:


  • Hypertension: 5 mg initially orally once daily, followed by a maintenance dose of 5 to 10 mg orally once daily (Maximum dose: 10 mg/day).
  • Angina Pectoris and Coronary Artery Disease: 5 to 10 mg orally once daily as a maintenance dose (Maximum dose: 10 mg/day).

Geriatric Patients:

  • High Blood Pressure: 2.5 mg orally as an initial dose once daily, followed by a maintenance dose of 2.5 to 10 mg orally once daily (Maximum dose: 10 mg/day).
  • Angina: 5 mg as an initial dose orally once daily, with a maintenance dose of 5 to 10 mg orally once daily (Maximum dose: 10 mg/day).

Pediatric Patients (6 to 17 years):

  • High Blood Pressure: 2.5-5 mg maintenance dose orally once daily (Maximum dose: 5 mg/day).


Amlodipine’s applications in managing hypertension, angina, and heart-related risks make it a valuable medication. However, its use requires a thorough understanding of potential side effects and proper dosage guidelines, ensuring optimal health outcomes. Always consult a healthcare professional for personalized advice and recommendations. More about medicine and supplements on DrugsBank.

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