Cefuroxime: Uses, Side Effects, Dosage

Cefuroxime belongs to a group of drugs known as cephalosporin antibiotics. Cefuroxime oral pill is a prescription medication that is available as the brand-name medication Ceftin, among others. Additionally, it is available in generic form.

Cefuroxime was initially approved by the Food and Drug Administration (FDA) under the brand name Ceftin, made by GlaxoSmithKline, in 1987.

Cefuroxime axetil Uses

Cefuroxime is a broad-spectrum antibiotic used to treat many different infections, including pharyngitis, otitis media, sinusitis, and bronchitis.

  • Acute Bacterial Otitis Media
  • Pharyngitis/Tonsilitis
  • Skin Care Illness
  • Sinusitis
  • Lyme disease
  • Bronchitis
  • Cystitis
  • Gonococcal Infection
  • Pyelonephritis


Cefuroxime is a beta-lactam antibiotic. It inhibits both the third and final stages of bacterial cell wall synthesis. By binding to particular penicillin-binding proteins (PBPs) located inside the bacterial cell wall.


You Shouldn’t take cefuroxime for those who:

  • Are allergic to cefuroxime or some of the other components in the medication
  • Are allergic to penicillin
  • Are allergic to additional antibiotics like cefaclor, cefdinir, Keflex (cephalexin), or antibiotics at the cephalosporin course
  • Have liver or kidney problems.
  • Have Infection
  • Have Bad eating habits or suffer from malnutrition.
  • Have you recently had a possible disease or inflammation of your intestines while or after taking antibiotics?


Cefuroxime is contraindicated in the following conditions.

  • History of hypersensitivity (e.g., anaphylactic reaction) to some other kind of beta-lactam antibacterial agent (penicillins, monobactams and carbapenems).

Side effects

Common side effects of injectable and oral cefuroxime comprise the following:

  • Upset stomach
  • Allergic reactions
  • Vomiting
  • Yeast infection
  • Diarrhea
  • Stomach pain

Unwanted severe effects of cefuroxime include but are not limited to the following:

  • A life-threatening allergic response known as anaphylaxis in Which You Might have difficulty breathing, your throat closes up, and your skin breaks out into hives.
  • Intense and potentially life-threatening skin reactions such as Steven-Johnsons syndrome or toxic epidermal necrolysis (TENs)
  • Swelling of the face, such as lips, eyes, tongue, mouth, and throat
  • Blood ailments, including low platelet count or reduced levels of blood cells
  • elevated levels of white blood cells
  • Seizures
  • A severe form of nausea noticed by loose, watery feces along with a foul odor that Is Significantly worse than ordinary

Cefuroxime at Pregnancy & Lactation

Cefuroxime falls into class B. No proper studies have been performed on humans with cefuroxime. In animal research, pregnant animals were given this medicine, and the infants didn’t demonstrate any healthcare problems associated with this drug.

Cefuroxime was detected in breast milk. Due to the potential for adverse reactions in nursing infants from cefuroxime, an option ought to be made whether to discontinue nursing or to prevent the use of the medicine.


Your healthcare professionals may already know about any potential medication interactions and might be monitoring you for it. Don’t start, stop, or change the dosage of any medicine before checking with them first. Before using this medicine, tell your doctor or pharmacist of all prescription and nonprescription/herbal products that you can use, especially.

  • Blood thinners” (e.g., warfarin),
  • Live vaccines.
  • Concomitant use of probenecid is not recommended.
  • Although many antibiotics likely don’t influence hormonal birth control, like tablets and patches, or rings, some antibiotics can diminish their efficacy.
  • Make Sure You ask your doctor or pharmacist if you should use additional reliable birth control procedures While using this antibiotic.

Cefuroxime Dosage 

Cefuroxime is generally taken twice per day, with or after meals.

If you need to remember to take a dose of cefuroxime, take it as soon as you remember unless it is almost time for the next dose. Don’t take a double dose to make up for the missed dose.

Like all antibiotics, it’s essential to complete the prescribed course of cefuroxime, even in the event that you are feeling better or the disease appears to have cleared up.

Adult dose

  • For acute otitis, media 500 mg twice per day
  • For cystitis, 250 mg twice per day
  • For Pyelonephritis, 250 mg twice per day
  • For Lyme disease, take 500 mg twice per day.

Dose for children weigh less than 40 kg.

  • For acute tonsillitis and pharyngitis, acute bacterial sinusitis is 10 mg/kg twice per day to a max of 125 mg twice per day.
  • For acute otitis media, 15 mg/kg twice per day to a maximum of 250 mg twice per day.
  • For cystitis, 15 mg/kg twice per day to a maximum of 250 mg twice per day
  • For Pyelonephritis, 15 mg/kg twice per day to a maximum of 250 mg twice per day for 10 to 14 days
  • For Uncomplicated skin and soft tissue infections, 15 mg/kg twice every day to a maximum of 250 milligrams
  • For Lyme disease, 15 mg/kg twice per day to a maximum of 250 mg twice per day for 14 days (10 to 21 days).

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