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Asthalin inhaler: Uses, Side Effects, Dosage etc

Salbutamol is an active substance in Asthalin Inhaler and is used to treat respiratory diseases, asthma, lung diseases and other diseases. Salbutamol belongs to a class of medicines called bronchodilators and especially β2-adrenergic agonists. Asthalin inhaler contains a propellant 1 which delivers 100 ml of salbutamol as an aerosol in the lungs each time the inhaler is pressed. Each inhaler contains at least 200 actuations. Asthalin inhaler is used to treat and prevent the following conditions: Asthma Respiratory disease Lungs diseases Chronic bronchitis, Emphysema. Relieve breathing difficulties caused by brochospasm Prevent exercise induced bronchospasm, Allergy induced asthma to a known allergens like pollen or cats. Salbutamol works by acting on receptors within the lungs known as beta 2 receptors. once salbutamol stimulates these receptors it causes the muscles in the airways to relax. this enables the airways to open.By opening the airways, salbutamol makes it easier to breath. The most common side effects associated with the use of asthalin inhaler is Headache, Tremor, Restlessness, Palpitations Difficulty in sleeping. While serious side effects include the following: Feeling shaky Dry mouth Shortness of breath Pounding Wheezing Irregular heartbeat Skin rash Hoarseness Tightness in the chest Cough. Consult your doctor if you observe any of the following side-effects, especially if they do not go away. Asthalin inhaler (Salbutamol) shouldn’t be used if you’re pregnant or breastfeeding, assume you will be pregnant or are about to have a baby unless you’re advised to do so by your doctor. ask your doctor or pharmacist for advice before taking this drugs. Salbutamol should be used with caution in the following conditions: Coronary insufficiency, Cardiac arrhythmias, Hypertension, Convulsive disorders, Hyperthyroidism Diabetes mellitus. Hypokalemia. Asthalin Inhaler is contraindicated in case of hypersensitivity to salbutamol or any of the inactive ingredients present in the asthalin inhaler. If you are taking other medicines at the same time, the effects of Asthalin Inhaler may change. This may increase the risk of side effects or may cause your medicine to not work properly. Tell your doctor about all the medicines, vitamins and herbal supplements you use to help your doctor prevent or manage drug interactions. Asthalin Inhalator can interact with the following substances and products: Digoxin Aminophylline Levalbuterol. Atomoxetine Drugs used for depression Methyldopa Steroids Beta-receptor Theophylline Tricyclic antidepressant (TCA) drugs Diuretics Monoamine oxidase inhibitors (MOAI) The dosage of Asthalin Inhaler for various indications is given below:   Usual Adults dose For relief of acute episodes of bronchospasm:  1 or 2 puffs as necessary. The maximum dose is up to 8 puffs in 24 hours. Usual Children Dose For relief of acute episodes of bronchospasm:  Half the adult dose. Usual Adults To prevent allergen or exercise-induced bronchospasm:  Two inhalations, 15 minutes prior to exercise or exposure to allergen. The maximum dose is 2 puffs, up to 4 times a day. Usual Children To prevent allergen or exercise-induced bronchospasm:  Half the adult dose. Keep medications at room temperature away from heat and direct light. Do not freeze medications unless required by the package insert. Keep medications away from children and pets.

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Zerodol SP: Uses, Side Effects, Mechanism, Dosage

Zerodol SP prepared by IPCA Laboratories is  the combination of three drugs, such as Aceclofenac, acetaminophen and serrathiopeptidase. Acetaminophen, known as paracetamol, is used to treat pain and fever. It is usually used to relieve mild to moderate pain. Aceclofenac (brand name: Airtal) belongs to a group of drugs, steroidal anti-inflammatory drugs (NSAIDs) and to treat pain and inflammation associated with osteoarthritis, rheumatoid arthritis and ankylosing spondylitis. It is also used in fever, toothache headache, postoperative pain. Serratopeptidase is a proteolytic enzyme obtained from silkworm. It is used to reduce pain and inflammation associated with symptoms such as back pain, arthritis, tension headaches and migraines. Composition Aceclofenac 100 mg Serratopeptidase 15 mg Paracetamol 325 mg. Mechanism of action Aceclofenac blocks the effect of cyclooxygenase enzymes. These enzymes help with the production of other chemicals in the body called prostaglandins. Prostaglandins are produced in damaged or injured areas and cause pain and swelling. The effect of cyclooxygenase enzymes to block the production of prostaglandins is reduced, thus relieving pain and inflammation. Serratopeptidase helps the body break down proteins. Paracetamol increases the pain threshold and increases blood flow through the skin, heat loss and sweating. Zerodol SP Uses Zerodol SP Tablet is usually used to treat fever, muscle pain, but there are some other conditions where it can be considered such as: Bones and joints pain Toothache Muscles pain Bloating Ear pain Headache Periods pain Migraine Pain caused by nonaticular rheutism Rheumatoid arthritis Osteoarthritis Ankylosing spondylitis Sore throat Ear infections Blood clots Swelling Fever Cold & Flu Lumbago Ischiadynia. Also, Read Arthrozene Review: Does this Joint Supplement work? Heal n Soothe Review: Does it work or is it worth it? Side Effects Zerodol SP can cause side effects. Although they do not occur in most cases, some effects can be serious. This is especially true if you take more than the recommended dose. These are some of the expected side effects associated with the use of Zerodol SP tablets: Allergic Reaction due to paracetamol or any other ingredients. Nausea Vomiting Gas, Flatulence Abdominal Pain Dizziness Constipation Diarrhea Indigestion Heartburn Note: This is not a complete list of possible side-effects.Consult Your Doctor in case of Serious side effects. Precautions: Before using Zerodol SP Tablet, please consult a doctor and avoid using Zerodol SP if You are/have: Allergic to paracetamol Severe cardiac impairment Driving and operate dangerous machinery Have Bleeding disorders With Alcohol Gastro-intestinal disorders History of gastroulceration Patients recovering after a surgery. Contraindications: Zerodol SP is Contraindicated in patients with Following conditions: Hypersensitivity Gastrointestinal bleeding, and Severe ulcer. Zerodol SP In Pregnancy: Zerodol SP is not safe to take if you are pregnant or are planning to be pregnant. Consult Your Doctor. Zerodol SP In Breast Feeding: Zerodol SP Can Pass to Breast Milk and is not safe to take if you are breastfeeding or are planning for breast feeding. Always Consult With Your Doctor Before Using This Medicine. Zerodol SP interactions If you are taking other medicines or complementary products at the same time, the effects of Zerodol Tablet may will change. This may increase the risk of side effects or your medication may not work properly. Tell your GP about all the medications, vitamins and herbal supplements you use, so your doctor can help you prevent or control drug interactions. It may interact with the following medications and products: Antihypertensive drugs Lithium Digoxin Corticosteroids Ethanol Note: This is not a complete list of drug interactions associated with the use of this medicine. Zerodol SP Dosage The usual Recommended dose for adult is 1-2 Tablets Per day with Foods. Frequently Asked Questions Q. 1 Is it safe to use during Pregnancy? Zerodol SP Tablet may be unsafe to use during pregnancy. Animal studies have shown adverse effects on the foetus, however, there are limited human studies. The benefits from use in pregnant women may be acceptable despite the risk. Please consult your doctor. Q.2 Is it safe to use while breast feeding? Zerodol SP Can Pass to Breast Milk and is not safe to take if you are breastfeeding or are planning for breast feeding. Always Consult With Your Doctor Before Using This Medicine. Zerodol Sp Contain Aceclofenac Which is not recommended for use in Breastfeeding. It’s better you ask your pharmacist or consult your doctor. Q. 3 Can Zerodol SP Tablet be used for bones and joints pain and toothache? Yes you can use this drug for toothache, joint and bones pain. Aceclofenac is used for tootache while paracetamol and serrathiopeptidase both are use for pain, fever and inflammation. Q. 4 What is Zerodol used to treat? Zerodol Sp is used for the treatment and prevention of conditions like Bones and joints pain, Toothache, Muscles pain, Bloating, Ear pain, Headache, Periods pain, Migraine and many other. Check above. Q. 5 What are the side effects of Zerodol tablets? The most common side effects are nausea, vomiting, gas, flatulence, heartburn etc. This is not a complete list of side effects you can check it above. Q. 6 Is Zerodol Sp a painkiller? Zerodol is the combination of three active ingredients thet can be used for the relieving of certain types of Pain. Q. 7 Can I take Zerodol SP Tablet with alcohol?                              No, you can’t take Zerodol SP with alcohol as it may increase the risk of side effects. Q. 8 Is it habit forming? No, Zerodol Sp is not a habit forming medicine. Q. 9 Should I use Zerodol SP Tablet empty stomach, before food or after food? This can be taken on an empty stomach; however doctors generally prescribe Zerodol to be taken with food. Q. 10 How Zerodol SP Works? Zerodol SP reduces pain and inflammation by blocking the release of certain chemicals in the brain that produce pain and inflammation signals in the nervous system. Paracetamol is an antipyretic that prevents the brain from raising body temperature or causing fever. Aceclofenac is a non-steroidal anti-inflammatory drug that blocks pain and inflammation. Serratiopeptidase is an enzyme that breaks down the abnormal proteins

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Cheston Cold: Uses, Side Effects, Mechanism,Dosage

Cheston Cold tablet is the combination of three active ingredients such as Cetirizine, Paracetamol, Phenylephrine. Cheston cold is manufactured by CIPLA. It is also available in oral suspension, and syrup forms. Cheston Cold Composition Cheston Cold Tablet is made from Cetirizine, (5 mg), Paracetamol (325 mg) Phenylephrine(10 mg). Cetirizine is a powerful second-generation antihistamine for the treatment of hay fever, allergy, angioedema, and urticaria. Paracetamol is known as acetaminophen used to treat pain and fever. It is usually used to relieve mild to moderate pain. Phenylephrine is a selective α 1; adrenergic receptor agonist, mainly used as a decongestant, as a means of expanding the pupil and for increasing the blood pressure of the phenethylamine class. Mechanism: Cetirizine blocks a natural substance that occurs during an allergic process in the body called histamine. Paracetamol increases the threshold of pain and increases blood flow through the skin, loss of heat, and perspiration. Phenylephrine helps relieve congestion in the nose by reducing blood flow in the nasal cavity. It causes confusion of blood vessels by stimulating the receptors in them. Cheston Cold Tablet Uses Cheston Cold Tablet is a medication that can be used for treating the following diseases, conditions, and symptoms: Allergy symptoms Cold Flu Fever Running nose Sneezing Headache Nasal decongestant Itching Joint pain Watery eyes Skin allergies Ear pain Periods pain Toothache Hypotensive conditions Intraocular tension Eye mydriasis Side Effects Cheston Cold Tablet generally well tolerated and does not have too many side effects. Though, it may have certain side effects like Stomach pain, Nausea Vomiting, Diarrhea, Head Ache Dry mouth, Tiredness Drowsiness Constipation Allergic reaction. Precautions Cheston Cold tablet is contraindicated in the following conditions: Allergic to Cheston Cold Tablet or any of its components. Hypersensitivity Coronary Artery Disease Kidney or Liver Disease Pregnancy Breastfeeding Thyroid problem If you suffer from asthma or any other breathing problems. You should avoid driving if you feel dizzy, drowsy, or sleepy after taking this medication. Pregnancy Cheston Cold Tablet may not be safe to use during pregnancy. Necessary studies have shown side effects in the fetus, but there are limited studies in humans. The benefits of using it in pregnant women may be acceptable despite the risk. Please contact your doctor. Drug interactions Before using your medicine, tell your doctor about your current list of medicines, about foods (eg vitamins, herbal supplements, etc.), allergies, existing illnesses, and current health conditions (eg, pregnancy, next surgery, etc.). Some health conditions may make you more prone to the side effects of the medication. The common drug interactions associated with the use of Cheston cold tablet are: Decongestants Antihypertensive medicine. Alcohol Digoxin Leflunomide Ketoconazole Sedatives Prilocaine. This is not a complete list of drug interactions and conditions that might interfere with this medicine. Before taking this drug, inform your GP about all your present medications. Cheston Cold Dosage Take Cheston Cold tablets approximately 2 to 3 times a day. You can take this medication for about 2 to 3 days until you feel relieved. Take it as a whole. Do not chew, crush, or break. Cheston Cold tablet can be taken with or without food, but it is best to take it at a certain time. Take it with food if stomach upset occurs. Also, Read Best Folding Mobility Scooters & Wheelchairs HairMax Laserband Review: Does it work? Capillus Laser Cap Review: Does it work? FDA Cleared Hair growth Devices

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Sinarest Tablet: Uses, Side Effects, Mechanism, Dosage

Sinarest Tablet manufactured by Centaur Pharma and is the combination of three active ingredients such as Chlorpheniramine, Paracetamol and Phenylephrine. The composition of active ingredients in Sinarest Tablet is: Paracetamol – 500 MG Phenylephrine – 10 MG Chlorpheniramine – 2 MG   Chlorphenamine is a first generation antihistamine for the prevention of allergic symptoms such as rhinitis and urticaria. Its sedative effects are relatively weak compared to other first generation antihistamines. Paracetamol, also known as acetaminophen, is a commonly used medication that can help treat pain and reduce high temperatures (fever). It is usually used to relieve mild or moderate pain, such as headache. Phenylephrine is used to temporarily relieve congestive nasal, sinus and ear symptoms caused by a cold, flu, allergies or other respiratory diseases (eg, sinusitis, bronchitis). This medication works by reducing swelling in the nose and ears, which reduces discomfort and facilitates breathing. Uses of Sinarest Tablet Sinarest tablet is used in different types of medical conditions and symptoms such as Flu Cold Headache Fever Febrility Nase stiffness Allergy Hay fever Cephalalgia Toothache Ear pain Toothache Joint pain Periods pain Eye mydriasis Intraocular tension Hypotensive conditions Watery eyes Itchy throat/skin Urticaria Rhinitis Anaphylactic shock Note: Sinarest tablet may also used for diseases not listed here. How Sinarest Tablet Work? It is believed that acetaminophen (Paracetamol) acts mainly in the CNS, by increasing the pain threshold to increase both isoforms of cyclooxygenase enzymes inhibiting COX-1, COX-2 and COX-3 involved in the synthesis of prostaglandins (PG). Chlorpheniramine binds to the histamine H1 receptor. This blocks the action of endogenous histamine, which subsequently leads to temporary relief of the negative symptoms caused by histamine. Phenylephrine reduces nasal congestion by acting on alpha 1 adrenergic receptors in the arterioles in the nasal mucosa to create constriction. Sinarest Tablet Side Effects Side effects are unwanted symptoms caused by medical treatment. They are also known as “side effects” or “side effects.” All medications can cause side effects, especially if you do not take them as recommended. These include prescription medications, over-the-counter medications and herbal remedies and supplements. There is a list of some side effects associated with the use of Sinarest Tablet: Dizziness. Feeling nervous and excitable. Feeling sleepy. Shortness of breath. Not able to sleep. Liver damage. Blurred Vision. Allergic reaction. Not able to pass urine or change in how much urine is passed. A very bad skin reaction such as Stevens-Johnson syndrome/toxic epidermal necrolysis may occur. Precautions Do not take more than your doctor told you. More than what you’ve been told can increase your chances of serious side effects.Do not take the most synonymous tablet longer than your doctor has told you.Avoid driving and performing other tasks or actions that you need to be vigilant until you see how the synergy affects you. Avoid alcohol while taking Sinarest tablets. Talk to your doctor before taking other medicines and natural products that interfere with your actions. There have been very serious and sometimes fatal liver problems with the use of acetaminophen. Some people needed a liver transplant. Liver problems are more common in people who take more than 4,000 mg (milligrams) in one day. Often people took more than one drug with paracetamol. Talk to your doctor If you are taking warfarin, talk to your doctor. You may need to monitor your blood test more closely while taking sinarest tablets. Do not give Sinarte tablets to children under the age of 12 without first consulting your doctor. Do not use this medicine if you have been taking MAOIs such as isocarboxazid, linezolid, methylene blue, phenelzine, rasagiline, selegiline or tranylcypromine for the last 14 days. Sinarest Tablet Contraindications Sinarest Tablet is  contraindicated in following conditions: Hepatic impairment Hyperthyroidism Hypersensitivity Sinarest In Pregnancy & Breastfeeding Tell your doctor if you are pregnant or plan to become pregnant. You should discuss the benefits and risks of using this medication (acetaminophen tablets, chlorpheniramine and phenylephrine) while you are pregnant. Tell your doctor if you are breast-feeding. You have to talk about the risks for your baby. Dosage of Sinarest Tablet The usual dose in adults for cold and sinusitis symptoms is 2 tablets every 4 hours to exceed 8 tablets daily. The usual pediatric dose (more than 12 years) for the common cold and the breast is 2 tablets every 4 hours, no more than 8 tablets a day. Take this medication orally with or without food or as prescribed by your doctor. If stomach upset occurs, it may help to take this medication with food or milk. Drink plenty of fluids if you are taking this medication unless your doctor tells you to. The liquid helps loosen mucus from the lungs.  

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Acetylcysteine (Fluimucil): Uses, Side Effects, Dosage

ACETYLCYSTEINE (brand name: Fluimucil) also known as N-acetylcysteine ​​(NAC) is a modified amino acid and belongs to a group of medicines known as mucolytic. It is a precursor of glutathione (GSH) and acts fast to break down and excrete mucus.it is used  to clean the respiratory tract. Fluimucil is used as an antidote to the overdose of paracetamol (paracetamol) to prevent liver damage. It is used to reduce exacerbations of COPD. It is used to treat thick mucus in people with cystic fibrosis or chronic obstructive pulmonary disease. It may be effective in limiting nephrotoxicity due to radiographic contrast agents. It is used in certain lung diseases (such as pneumonia, emphysema, cystic fibrosis, bronchitis). Sometime it is used as a dietary supplement. It is also used in bronchiectasis. Pulmonary complications related to surgery. Use during anesthesia Cystic Fibrosis The mucolytic effect of acetylcysteine (Fluimicil) ​​is linked to the sulfhydryl group in the molecule. This group is likely to open disulphide bonds in the mucosa, reducing viscosity. Acetylcysteine (Fluimucil) Restores hepatic glutathione levels by producing the glutathione precursor L-cysteine. Glutathione must inactivate an intermediate metabolite (N-acetyl-p-benzoquinoneimine) of paracetamol, which is believed to be hepatotoxic. In the case of acetaminophen overdose, excessive levels of this metabolite are formed because the primary metabolic pathways (glucuronide and sulfate conjugation) are saturated. Common side effects are Nausea, Vomit, Heavy breathing Low potassium content Dizziness Blurred vision Pain in the joints and Diarrhea or constipation Include rare side effects Rashes, Fever A headache, Drowsiness; Runny nose Low blood pressure Oppression in the chest Swelling in the mouth and Liver problems Stop using Fluimucil and contact your doctor if If you are allergic to acetylcysteine ​​or any other similar medicine. Asthma and asthmatic condition. Duodenal ulcers Phenylketonuria. Before using Fluimucil,  tell your doctor or pharmacist about all the prescription and herbal products that you can use. Fluimucil should be avoided in combination with cefuroxime (an antibiotic). As the combination of acetylcysteine ​​with this drug increases the concentration of cefuroxime. Also avoid Fluimucil with other medicines for the treatment of cough. The intake of N-acetylcysteine ​​seems to increase the effect of nitroglycerin. Activated charcoal can bind these drugs in the stomach and prevent the body from absorbing them. Co-administration of N-acetylcysteine ​​with activated charcoal may reduce the effectiveness of poisoning prevention. Acetylcysteine (Fluimucil) is a Pregnancy category B from the FDA. It is not expected that acetylcysteine ​​will harm the unborn child. Tell your doctor if you are pregnant or planning to become pregnant during treatment. It is not known if acetylcysteine ​​passes into breast milk or if it could harm a breastfeeding baby. Tell your doctor if you are breast-feeding a baby. Usual dose for adults and children over 14 years:An effervescent tablet Fluimucil (200 mg), 2-3 times a day. Usual dose for children from 7 to 14 years:An effervescent tablet of fluimucil (200 mg), 1-2 times a day. The treatment should take 5 to 10 days. Dissolve an effervescent tablet in a glass of water, stir if necessary and drink. Note: The information on this website is for educational purposes only and is not intended for medical advice, diagnosis or treatment. Contact your doctor.

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Prebiotics: Uses, Sources & Side Effects

Prebiotics are non-digestible food ingredients that are used selectively in the colon to multiply healthy bacteria. They promote digestion and stimulate the production of valuable vitamins. They also promote the growth of beneficial bacteria (lactobacilli and bifidobacteria) to feed without the “bad” types. Good bacteria play an important role in regulating your immune system, inhibiting the growth of pathogens (disease-causing bacteria) and digesting food. Galactooligosaccharides (GOS) are the most advanced form of prebiotics They were first identified by Marcel Roberfroid in 1995. Prebiotic fiber passes undigested to the small intestine and ferment when they reach the colon. Researchers have found that probiotics are useful for increasing the beneficial bacteria already found in the intestine, which reduces the risk of disease and improves overall well-being. Prebiotic fiber are not as vulnerable as probiotic bacteria, since they are not affected by heat, gastric or time. The fermentation process also does not differ depending on the person. Prebiotic supplements are different from probiotic supplements, as they are very stable and reach the intestine intact. In addition, all prebiotics are not the same and some are more selective for good bacteria than others and offer them for the unique characteristics. Originally prebiotics were not classified as fiber connections, but recent research has shown that these compounds behave like other fiber forms. These days, prebiotic carbohydrates that have been studied in people, mostly fructans or galactans, both of which are fermented by anaerobic bacteria in the colon. “A prebiotic is a selectively fermented ingredient that allows specific changes, both in the composition and in the activity in the gastrointestinal microbiota that benefits the welfare and health of the host.” Probiotics Probiotics are live bacteria. This bacteria is found in certain foods or supplements such as Yogurt etc. They can be killed by heat, stomach acid, or simply die with time. Examples: Bifidobacteria and lactobacilli. Prebiotics: These are Non-living & Non-digestible fiber. They occur naturally in fruits and vegetables  such as garlic, asparagus, onion. They are resistant to stomach acid or other enzyme. They acts as a fertilizer for the good bacteria in your gut. Indigestion, Higher levels of inflammation, Lower immune function, Higher likelihood of weight gain and A raised risk for various chronic diseases. Prebiotic work naturally in your gut to feed existing good bacteria, helping them to grow and multiply. Important benefits can include the following: Prebiotics help “improve stool quality (frequency and consistency) Reduces the risk of gastroenteritis and infections. Improving the barrier function of the gut. It prevent cancer, Strengthening the immune system Lower inflammation and autoimmune reactions. Boosting overall digestive health. Help Lower Inflammation. Lowering some risk factors for cardiovascular disease. Enhancing your body’s nutrition by allowing better mineral and nutrient uptake. Contributing positively to your mental health. Minimising the risk of developing diarrhoea. Increasing absorption of calcium to improve bone density. Prebiotics Also Protect Bones Improved Moods. Regulate glucose. The Major Source of Prebiotics is dietary fibre.Following are some of the best source of prebiotocs Oatmeal Apple With Skin Onion and Garlic Wheat Bread Chicory Root Leeks Asparagus Barely Dandelion Greens Under-ripe bananas Acacia gum Jerusalem artichoke It Is generally well tolerated But Some Time It Cause Certain Side Effects Because Of Interaction With Normal Flora Of The Gut That’s Why Some People may find it difficult to use as it takes a few days for their system to adjust.Natural Prebiotics are as important and safe as your food but some prebiotics product may cause some side effects such as: Tummy gurgling Excess of gas in the intestine Abdominal bloating and Discomfort.

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100 Year Old Woman Gives Birth To A Baby Boy

ITALY – Anatolia Vertadella, a 100-year-old woman, has given birth to a baby after a successful transplant. The controversial transplantation is often criticized by medical professionals because of their advanced age. The illegal and controversial surgical operation was carried out in a private clinic in Turkey, where the European law on ovarian transplantation does not apply, admits the one-hundred-year-old mother who refuses to disclose the name of the clinic where the operation was performed. Although the husband of Miss Vertadella has died since 1998, the widow of the centenarians has found a sperm donor to make the birth possible. “I still love my deceased husband and desire to stay a widow until I leave this earth, but I needed the seed of this young fervent Catholic to fulfill God’s will,” she concluded. This 100-year-old Italian has given birth to a 9-pound baby after a controversial transplantation of ovaries criticized by doctors for their old age, Rivista Napoli reports. I am so grateful to have given birth to my 17th child. This is a true blessing and a testament to the power of the creator” she told local journalists. “I could not reproduce since I was diagnosed with ovarian cancer.” For a long time I believed that God punished me, but God is real and he hears our prayers, has given me fertility at an age that is nothing short of a miracle. , recognizes the fervent centenarian Catholic. The operation was completely legal in Turkey and was carried out by a handful of medical specialists. According to medical reports, the woman is in good health at her age and has many good years to share with her child.

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Scientists Discover Protein That can help suppress the growth of Cancer Cells

A research, published in the British Journal of Pharmacology, showed that both proteins significantly reduced the growth of almost all cancers and blocked the work of specific receptors on the surface of cells that led to division. Biologists found that the number of cancer cells decreased by 40-70% after one day compared to the tumor control samples. Molecular biologists from the Moscow State University and the Russian Academy of Sciences have discovered proteins that can suppress the growth of cancerous tumors. The genomes of humans and other multicellular organisms contain multiple groups of genes with special “instructions” that prompt their cells to self-destruct when certain conditions are met. As a rule, these reactions are not triggered by internal cellular processes, but by the contact of cell membranes with molecules emitting specific signals. As a result, the immune system can kill “rebellious” cells that threaten to cause cancerous tumors and purify the organism of old and weak cells. Dr. Mikhail Shulepko the Institute of Biochemistry of the Russian Academy of Sciences, co-author of a new study on the subject stated that special proteins in skin cells of mammals have a similar toxins of the structure snakes and other reptiles. Unlike their toxic “cousins”, which work to block the transmission of nerve impulses, mammalian proteins called SLURP do not act in the nervous system, but in all cells in general and accelerate or slow their growth The discovery of the scientists prompted them to consider whether such proteins could be used to fight cancer as a kind of “stop sign” against the proliferation of cancer cells. They tested this idea by cultivating skin, breast, lung and rectal cells in a laboratory and treating them with large amounts of the SLURP-1 and SLURP-2 type of  proteins. Injecting large amounts of SLURP-1 and SLURP-2 proteins into the cell broth also caused the cancer cells to produce even more of these same molecules, causing a chain reaction and destroying the cancer cells themselves. “We will continue to investigate how SLURP  works in other models of cancer, including cell cultures of primary tumors and human tumors implanted in the bodies of laboratory animals. If these effects are confirmed, it will be possible to view clinical trials for our protein, “he said. Shulepko. According to biologists, more work is needed to determine how exactly these proteins cause cancer cells to self-destruct and what role they play in the body’s work.

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Enalapril (Renitec): Uses, Side effects, Dosage

Enalapril (Brand Name:  Renitec) is a prodrug that belongs to the class of angiotensin-converting enzyme (ACE) inhibitors. Uses Of Renitec It is used under the following conditions It was used to treat high blood pressure. Lowering high blood pressure helps prevent strokes Heart attacks and Kidney problems It is also used to treat heart failure and Helps prevent left ventricular dysfunction Avoid enalapril (Renitec) if You are allergic to enalapril, other ACE inhibitors (type of drugs that “ENALAPRIL” are similar) or any of the other components of these tablets. You have more than 3 months of pregnancy. (It is also better to avoid “ENALAPRIL” in early pregnancy You have diabetes or kidney failure and are treated with antihypertensive medications that contain aliskiren. Mechanism of action of enalapril (Renitec) Enalapril is a medicine used to treat high blood pressure. It is in a class of medications called angiotensin-converting enzyme (ACE) inhibitors. ACE is an enzyme in the body that causes the formation of angiotensin II. Angiotensin II causes a narrowing of the arteries in the body and increases blood pressure. Side effects of Renitec The most common side effects that can occur with Enalapril include: Weakness Dizziness Cough Eruption Serious side effects Serious side effects and their symptoms may include: Liver problems Difficulty to breathe. Central nervous system problems High potassium content Swelling (angioedema) of the face, neck, tongue, lips, eyes, hands, feet, ankles, or calves Infection Kidney problems Enalapril (Renitec) in pregnancy Do not take enalapril if you are pregnant. If you become pregnant while taking Enalapril, contact your doctor immediately. Enalapril can harm the fetus. Enalapril Dose The usual oral dose for the treatment of hypertension is 2.5 to 40 mg once a day. It can also be administered twice a day in two separate doses. The dose for the treatment of heart failure is 2.5-20 mg twice a day. The usual starting intravenous dose is 1.25 mg administered over a period of 5 minutes every 6 hours. When a patient receives diuretic therapy, the initial intravenous dose is 0.625 mg every 6 hours.

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Scientists Explain Why Knuckle Cracking Makes That Awful Sound

The characteristic pop can be explained with three mathematical equations, say US  and France researchers. Science student Vineeth Chandran Suja broke class in France when she decided to investigate. He developed a series of equations with his professor, Dr. Ing. Abdul Barakat Ecole polytechnique to explain the typical sound that accompanies the release of the connection between the fingers and hand bones. “The first equation describes the pressure variations inside our joint when we crack our knuckles,” he told. “The second equation is a well-known equation which describes the size variations of bubbles in response to pressure variations. “And the third equation that we wrote down was coupling the size variation of the bubbles to ones that produce sounds.” His model confirms the idea that the sound of cracking is due to small bubbles that collapse in the fluid of the joint as the pressure changes. For decades scientists have been discussing the cause of the outbreak when we broke our knuckles. With the help of computer models, a French team of researchers could have found the answer. As the authors in the new article published in Scientific Reports, cracking ankles caused by a “collapsing cavitation bubble in the synovial fluid inside a metacarpophalangeal joint during an articular release.” Easier is the sound of microscopic gas bubbles collapsing within the finger joint, but not completely. Scientists first proposed this theory almost 50 years ago, but the latter used a combination of laboratory experiments and a computer simulation to amplify the case. It seems strange, but scientists have studied this physical feature since the early 1900s and could not reach consensus on the cause of the burst sound. The seemingly endless debate is the result of unconvincing experimental evidence and the difficulty of seeing the process in action: the whole phenomenon lasts only about 300 milliseconds. However, what the scientists have agreed that cracking ankles is not something everyone can do, not all fingers can produce the sound of pop, and it takes about 20 minutes before an ankle is broken again. To clarify things, and to add more support for existing experimental data, V. Dran Suja and Abdul Bakarat of the Ecole Polytechnique in France took geometric representations of the metacarpophalangeal joint (MCP) where the eruption takes place and were mathematical equations that improved computer simulations of ankle cracking , Or more precisely, computer simulations that showed what happened just before the sound on our fingers. It also confirms why some people can not break their knuckles. If you have a large gap between the bones in your knuckles, the pressure in the fluid will not drop enough to activate the sound.

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