Sparfloxacin: Uses, Side Effects, Dosage

Sparfloxacin belongs to a group of broad spectrum antibiotics that’s administered to treat bacterial disease .

However, this medicine won’t work for viral diseases like influenza and the frequent cold.

Keep in mind that using a antibiotic repetitively for trivial problems or for issues not due to bacteria can direct the bacteria to become resistant to this antibiotic. Hence the antibiotic will reduce its effectiveness over a time period.

Sparfloxacin can be taken with meals or on an empty stomach, or with milk products.


Sparfloxacin is utilized in treating:

  • Escherichia coli Infection
  • Chlamydia Infection
  • Pneumonia
  • Haemophilus Infections
  • Klebsiella Infections
  • Proteus Infections
  • Salmonella Infections
  • Streptococcal infections
  • Staphylococcal infections


The bactericidal activity of sparfloxacin results in inhibition of these enzymes topoisomerase II (DNA gyrase) and topoisomerase IV, which are required for bacterial DNA replication, transcription, repair, and recombination.

Side effects

Most side effects are mild to moderate in strength and disappear during therapy.

  • Diarrhea,
  • Vomiting,
  • Nausea, ,
  • Sleeplessness,
  • Dry mouth, or
  • stomach pain might happen.

If these effects persist or worsen, notify your physician immediately.

Report promptly:

  • skin irritation/swelling,
  • rash, redness,
  • itching(potential sun sensitivity response or allergy).

Very unlikely but report:

  • Mood/mental alterations,
  • Eye difficulties,
  • Unusual change in the amount of urine,
  • fever,
  • rash,
  • muscular /joint pain,
  • difficulty breathing,
  • yellowing eyes/skin,
  • bleeding/bruising.

Utilization in pregnancy & Breast Feeding

  • This medication isn’t suggested to be used during pregnancy unless absolutely needed. Ask your physician about the possible benefits and risks before deciding to take this medication.
  • Use of this medication isn’t recommended in women who breastfeed because of the adverse effects on the progression of the baby’s joints. Use only if clearly needed under the oversight of their physician. Tracking of unwanted effects such as diarrhea and diaper rash is essential.

Contraindications of Sparfloxacin

  • Avoid taking this medication when you’ve got a known allergy to any other fluoroquinolones.
  • Avoid if you’ve got a previous history of tendinitis or tendon rupture after using this medication.
  • Avoid if you’ve got a past history of myasthenia gravis or family history of myasthenia gravis.


For treatment of disease:

  • Adults -400 milligrams (mg) on the very first day, then 200 mg once per day for another nine days.
  • Children younger than 18 years of age–Use and dose must be determined by your physician.
  • If you forget a dose of this medicine, take it as soon as possible. But if it’s almost time for the next dose, skip the missed dose and return to your regular dosing schedule. Don’t double doses.

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