Olanzapine: Uses, Side Effects, Dosage

Olanzapine is a member of a drug class called atypical antipsychotics.Olanzapine is a medication that’s used to deal with schizophrenia and severe manic episodes linked with bipolar disorder.

Olanzapine Uses

  • Olanzapine is used to treat mental/mood disorders such as schizophrenia and bipolar I disorder.
  • It is used with fluoxetine to treat different ailments. These include disease brought on by bipolar I disorder in addition to disease that can not be controlled with other medications.

How it functions

Olanzapine is a member of a category of drugs known as atypical antipsychotics.

It is not known precisely how olanzapine functions. It is believed that it might help to modulate the quantity of certain substances (serotonin and dopamine ) in mind to help control your disposition.

It may work by blocking receptors for several neurotransmitters (chemicals that nerves use to communicate with each other) in the brain. It binds to alpha-1, dopamine, histamine H-1, muscarinic, and serotonin type 2 (5-HT2) receptors.

Olanzapine Side Effects

Following are some of the side effectd associatd with the use of Olanzapine:

  • Drowsiness, Nausea , lightheadedness, stomach upset,
  • Dry mouth, constipation, weight gain might happen.
  • Olanzapine could rarely cause a condition called tardive dyskinesia.
  • This drug may rarely create your blood glucose increase, which may cause or aggravate diabetes.
  • Olanzapine may also cause rise in your own blood cholesterol (or triglyceride) amounts, particularly in teens.
  • Insomnia, tremers, restlessness may also occur.


Bear in mind that your doctor has prescribed this medicine since he or she has understood the benefit to you is greater than the possibility of side effects. A lot of people using this medication don’t have severe side effects.

Use in pregnancy & Breast feeding

  • Use of this medication isn’t recommended during pregnancy because it may cause developmental defects in the unborn child. As there’s a lack of conclusive evidence from individual studies, ask your physician if you’re pregnant. Each of the possible benefits and risks should be thought about before taking this medication.
  • Use of this medication isn’t suggested for breastfeeding mothers since it is excreted via breast feeding. Although the effects aren’t determined, it is encouraged to seek advice from your health care provider prior to taking the medication. Close observation of symptoms in babies may be needed in some instances.


  • The maximum dose is 20 milligrams per day. The suggested dose of extended release dose is 150-405 mg every two or four weeks.
  • The dose may be increased by 5 milligrams per day at 24 hour periods.
  • The maximum dose is 20 milligrams per day.
  • The typical dose for treating agitation  because of schizophrenia or bipolar disease is 10 mg administered by intramuscular injection (immediate release). Added 10 mg doses could be treated, but the effectiveness of overall doses higher than 30 mg per day haven’t been adequately assessed.

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