Fexofenadine: Uses, Side effects, Dosage

Fexofenadine is a non sedative antihistamine drugs however it can cause drowsiness in some people.

  • It is used in seasonal allergic rhinitis (Hay fever) and chronic urticaria (Hives) such as itching, swelling and rashes.
  • Fexofenadine competes with free histamine for binding at H1-receptors within the gastrointestinal tract, massive blood vessels, and bronchial smooth muscle. This blocks the action of endogenous histamine, that subsequently ends up in temporary relief of the negative symptoms (eg. nasal congestion, watery eyes) brought on by histamine. Fexofenadine exhibits no anticholinergic, antidopaminergic, alpha1-adrenergic or beta-adrenergic-receptor obstruction effects.
  • Fexofenadine blocks histamine receptors and so stops the chain reaction that causes the symptoms of the allergy. It usually starts to work within half an hour to an hour after taking a dose.
  • Do not take Fexofenadine if you are pregnant, unless necessary and it is also not recommended during breast-feeding.

Fexofenadine Side effects

  • Common Side effects include Cough, fever, or stomach upset may occur. Many people using this medication do not have serious side effects.A very serious allergic reaction to this drug is rare. However, get medical help right away if you notice any symptoms of a serious allergic reaction, including: rash, itching/swelling (especially of the face/tongue/throat), severe dizziness, trouble breathing.
  • Usual Adult Dose for Allergic Rhinitis ie 180 mg orally per day OR 60 mg orally twice a day.
  • Usual Adult Dose for Urticaria is 180 mg orally once a day OR 60 mg orally 2 twice a day.
  • Usual Pediatric Dose for Allergic Rhinitis fir 6 months to 2 years is 15 mg orally 2 times a day and for 2 years to 11 years is 30 mg orally 2 times a day and for 12 years and older is 180 mg orally once a day OR 60 mg orally 2 times a day.

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