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Chinese University Announces World’s First Lungs Regenerative Therapy

Tongji University has announced a breakthrough in the treatment of Lungs Regenerative Therapy for lung disease through tissue repair through stem cell transplantation.The research results have been published in Protein & Cell journal. Lungs Regenerative therapy works by removing stem cells from patients’ airways and allowing them to grow many times before being transplanted into the lungs of patients. “Lung diseases are the third most common cause of death from cardiovascular disease and cancer, while traditional methods do not work that effectively,” said Zuo Wei, a professor at Tongji University, who led the research team. Lung transplant surgery is largely limited due to the donor’s lack of lungs as well as severe side effects as a result of rejection, he said. Regenerative stem cell-based therapy with patient own cells is probably the biggest hope for patients with lung disease, he said. The Lungs Regenerative therapy can be used in diseases such as chronic obstructive pulmonary diseases, bronchiectasis and interstitial lung diseases. The team works with Shanghai East Hospital, which is affiliated with Tongji University, and the therapy has proven to be effective in the treatment of lung tissue after its use in six hospitalized patients with interstitial lung disease. Dozens of stem cells have been brushed from their airways and expanded millions of times. They were then transplanted into the patient’s lungs, where the stem cells were transformed into new alveolar and bronchial structures and the injured parts were repaired and replaced. The breathing and walking ability of the patients improved. The CT images also showed repair and replacement of the stem cells in the injured parts. In addition, two patients with bronchiectasis said their symptoms, including cough and asthma, had been alleviated. The team’s technology is the first in the world and the research project has been approved by China’s National Board of Health and Family Planning and the Chinese Food and Drug Administration.

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Gaviscon:The Best Medicine For Heart Burn & GERD

Gaviscon is the combination of three active ingredients like Sodium alginate, sodium bicarbonate, and calcium carbonate in a suitable flavored vehicle like peppermint or aniseed flavor. Gavison is a sugar-free suspension manufactured by Reckitt Benckiser. Active Ingredients: Sodium alginate, Sodium bicarbonate, and Calcium carbonate Relieving the symptoms of gastro-oesophageal reflux, Heartburn including heartburn in pregnancy or following meals. Acid regurgitation. Too much Stomach Acid or Stomach Upset. Sodium Alginate 250 mg Sodium Bicarbonate 133.5 mg Calcium carbonate 80 mg/5ml Sodium (Na+)/5ml=3.1 mmol. Preparations containing Alginate Like Gavison. Alginate In the presence of the calcium carbonate it reacts with the acid in the stomach to form a viscous gel (Raft or a protective barrier) on the surface of stomach contents, thereby reducing symptoms of reflux. That viscous layer acts as a strong physical barrier and helps to keep stomach contents in the stomach as it floats on the surface of the stomach contents. This increase in viscosity of stomach contents and can protect the oesophageal mucosa from acid reflux. This raft stops stomach acid from escaping up into your food pipe. Apart From Alginate Gaviscon also contains an antacid that neutralizes excess stomach acid and reduces pain and discomfort. You are allergic or intolerant to any ingredient of the medicine. You are on a strict salt or sodium-restricted diet, for example, those with heart or kidney disease.As Gaviscon contains sodium and may not be suitable for Such Conditions. You have high levels of calcium in your blood, or with a history of kidney stones that contain calcium. As it contains calcium so may not be suitable for such people. Generally, It is well tolerated and there are very less and rare side effects related to the use of Gaviscon.some people have experienced; Allergic reactions, such as an itchy rash (urticaria), breathing difficulties due to a narrowing of the airways (bronchospasm), or anaphylaxis. Gaviscon can cause nausea, constipation, diarrhea, or a headache. Diarrhea because of Magnesium Dizziness and Fainting. Rare but very serious side effects like; Black/tarry stools, Irregular heartbeat, mental/mood changes (e.g., confusion), Deep sleep, Pain with urination, Stomach/abdominal pain, Vomit that looks like coffee grounds. It can be used to relieve indigestion and heartburn associated with pregnancy or when breastfeeding. However, be sure not to take more than the recommended dose. The usual adult dose is 10-20 ml after meals and at bedtime. (2-4 Teaspoon) The usual dose for children age 6-12 years is 5-10 ml after meals or at bedtime. Do not take Gaviscon for longer than 7 days without checking with a doctor. Take Gaviscon up to 4 times a day. Related Articles Important Information About Esomeprazole Motilium: Uses, Dose, Side Effects, etc

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Clonazepam (Rivotril): Uses, Side Effects,Mechanism & Dosage

Clonazepam (Brand name Rivotril) belongs to a group of drugs known as Benzodiazepine.Other members of This group are diazepam, alprazolam, Lorazepam, and Flurazepam.Generally, these drugs are used as a sedative, or to decrease anxiety and Seizures. Clonazepam is available as Rivotril Injection 1 mg/mL Rivotril Tablets include; Rivotril 0.5 mg Rivotril 2 mg  (Rivotril 2 mg tablet is used is a very effective medicine for the treatment of seizures of different types. It is also used to treat panic attacks and sleep disorders.) Klonopin Tablets. Rivotril Uses Rivotril (Clonazepam) is used primarily as an anticonvulsant in the treatment of; Absence seizures, Petit mal variant seizures (Lennox-Gastaut syndrome), Akinetic and myoclonic seizures, and Nocturnal myoclonus. It can also be used for the treatment of panic disorders. Pharmacokinetics Clonazepam is rapidly and completely absorbed after oral administration. The absolute bioavailability of clonazepam is approximately 90%. C max, oral administration = 1-4 hours. The biotransformation occurs mainly by reduction of the 7-nitro group to the 4-amino derivative. This derivative can be acetylated, hydroxylated and glucuronide. 85% bound to plasma proteins. and the half-life of clonazepam is 30 to 40 hours. It is highly metabolized, with less than 2% unchanged Clonazepam excreted in the urine. Clonazepam metabolites are excreted by the kidneys. Clonazepam is also acetylated via NAT2. Rivotril Mechanism Of Action Benzodiazepines act on specific receptors in the CNS. These are located on a complex glycoprotein molecule that surrounds a chloride channel.This Glycoprotein act as a GABA Receptor.This GABA receptor is made up of five subunits, a pentameric structure.These Five Subunits are selected from eight types if polypeptides, alpha, beta, gamma, delta, epsilon, Pi, Rho, and Theta.There are six different types of alpha, four types of beta and three types of gamma subunits.Alpha, Beta and Gamma subunits are the major polypeptide of the GABA receptors and their presence is essential for normal function of the receptor.They are distributed in various combinations in different parts of the CNS.Clonazepam enhances the activity of gamma-aminobutyric acid (GABA), which is a major inhibitory neurotransmitter in the central nervous system.Binding of GABA on these receptors causes the opening of chloride channels.This causes passage of chloride ions into neuron increasing negative ions inside the neurons.This result in hyperpolarization of neurons and these are difficult to be depolarised. Rivotril Side Effects The more common side effects of clonazepam oral tablet can include: Dizziness A headache Weakness Drowsiness Amnesia Confusion Depression Problems with walking and coordination Problems with memory Fatigue While Serious side effects include the following: Depressed mood or thoughts of suicide (harming yourself) Seizures Respiratory Depression Low Blood Pressure Increased Heart Rate. Don’t Use Rivotril If  You Have acute narrow or closed angle glaucoma You Are allergic to clonazepam or any ingredients of the medication You Have had an allergic reaction to any other medicine of benzodiazepine group.s You have myasthenia gravis You have sleep apnea You have severe breathing problems You have a severe liver disease. Rivotril In Pregnancy If you take Clonazepam during pregnancy, your baby is at risk of serious birth defects. These defects can occur in the first month of pregnancy, even before you know that you are pregnant. Congenital malformations may even occur in children born to women who are not on medication and have no other risk factors. This medicine should be used during pregnancy only in severe cases where it is necessary to treat a dangerous condition in the mother. Clonazepam Dosage  Rivotril injection, Clonazepam 1 mg /ml in Solvent for dilution with 1 ml water for injections immediately before injection. The dose of Klonopin Tablets and Rivotril Tablet (Containing Clonazepam) is tailored to the patient’s needs. For adult convulsions, the starting dose is 1.5 mg daily in 3 divided doses.The dosage may be increased from 0.5 to 1 mg per day every 3 days until seizures are controlled or side effects prevent further dose increase. The maximum dose is 20 mg per day. The starting dose for panic disorder is 0.25 mg twice daily. The dose may be increased to the target dose of 1 mg daily after 3 days. Related Article: Pharmacology Of Benzodiazepines

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Flixotide (Fluticasone): Uses, Side Effects, Dosage

Flixotide is a brand name for fluticasone – a drug also known as corticosteroids prevents the release of substances in the body that cause inflammation. It is a prescription-only medicine. Flixotide the respiratory system protects against overstimulation. This medication reduces hypersensitivity reactions in the lungs and reduces inflammation. Flixotide is taken by inhalation and is available in two types of inhalers: Flixotide Evohaler and Flixotide Accuhaler Inhaler. Flixotide Accuhaler is available in three strengths: Flixotide Junior Accuhaler 100 micrograms fluticasone propionate in a blister pack Flixotide Accuhaler 250 micrograms fluticasone propionate in a blister pack Flixotide Accuhaler 500 micrograms fluticasone propionate in a blister pack The Flixotide formulation contains the active substance fluticasone and lactose powder as an inactive ingredient (containing milk proteins). Flixotide uses Inhaled fluticasone propionate provides prophylactic treatment for asthma. Mild or Light Asthma (Adults): Patients who regularly need symptomatic intermittent bronchodilator treatment for asthma. Moderate asthma (adults): patients with unstable asthma or deteriorates despite prophylaxis or bronchodilator alone. Severe asthma (adults): Patients with severe chronic asthma and patients who depend on systemic corticosteroids to control symptoms adequately. With the introduction of inhaled fluticasone propionate, many of these patients can significantly reduce or eliminate their need for oral corticosteroids. Is Flixotide a Preventor? Fluticasone, which is taken by inhalation, is known as “Preventer”. This is because it is taken regularly every day to reduce inflammation in the lungs and prevent asthma attacks. Symptoms usually improve four to seven days after the start of treatment. However, it is important to use this medication regularly even after an improvement in the symptoms of asthma to prevent a recurrence. How does Flixotide work? (Mechanism Of Action) Flixotide contains the active substance fluticasone propionate, a type of medication known as a corticosteroid. When fluticasone is inhaled into the lungs, it is absorbed into the cells of the lungs and respiratory tract. Here, it prevents the release of certain chemicals from the cells. These chemicals are important for the immune system and are normally involved in the production of immune and allergic reactions that lead to inflammation. By reducing the release of these chemicals into the lungs and airways, inflammation is reduced. In asthma, the airways shrink due to inflammation and can also be blocked by mucus. This makes it difficult to get in and out of the lungs. By preventing inflammation and excessive mucus formation, fluticasone helps prevent asthma attacks. It is not used to treat an asthma attack. Side Effects of Fluticasone (Flixotide) This medication may cause side effects, including: Nausea Vomit Indigestion (Very Rare) A headache, Painful tongue Unpleasant taste in the mouth. Husky voice; A sore throat Raised blood sugar level (Very Rare) Hypersensitivity reactions such as rash, itching, swelling of the face, and anaphylaxis may occur. High doses and rarely normal doses can suppress the adrenal glands and affect their ability to produce natural cortisone. Avoid using This drug and consult your doctor if you are allergic to fluticasone or any other ingredient in this medicine; or if you have a viral infection and if you have tuberculosis. Flixotide during pregnancy It should not be used by pregnant or breastfeeding women without consulting a doctor. Flixotide Dose (Fluticasone) For adult patients with mild asthma, a typical starting dose is 100 micrograms twice daily. In moderate and more severe asthma, starting doses may need to be 250 to 500 micrograms twice daily. Where the additional clinical benefit is expected, doses of up to 1000 micrograms twice daily may be used. The initiation of such doses should be prescribed only by a specialist in the management of asthma (such as a consultant physician or general practitioner with appropriate experience). The dose should be titrated down to the lowest dose at which effective control of asthma is maintained. For Children, over 4 years of age the typical doses will be 50 to 100 micrograms twice daily. Many children’s asthma will be well controlled using the 50 to 100 microgram twice-daily dosing regimen. For those patients whose asthma is not sufficiently controlled, additional benefit may be obtained by increasing the dose up to 200 micrograms twice daily. The maximum recommended dose in children is 200 micrograms twice daily. Related Article: Salbutamol: Uses, Side Effects, Dosage

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Ginkgo Biloba (Tebonin): Uses, Side Effects, Dosage

Gingko Biloba (Brand Name: Tebonin) is a popular supplement and one of the best selling herbal medicines Gingko Biloba has been used in medicine for over 1000 years. Tebonin, manufactured by the German company Dr. Willmar Schwabe GmbH & Co KG. Clinical research has shown that Tebonin is an effective treatment for a range of conditions. To date, more than 60 controlled clinical trials of Ginkgo biloba extract have been published in international medical journals. Tebonin is used for a wide range of conditions such as; Impaired micro-circulation. Natural support for healthy & normal brain & cognitive function, Mental performance, Concentration, Alertness, Focus, Relieve tinnitus (the ringing sound some people have in their ears), Edema, inflammation, Free-radical toxicity associated with traumatic brain injury (TBI), Alzheimer’s dementia, stroke, vasoocclusive disorders, and aging. According To Latest News Tebonin’s efficacy in boosting brain function is one of the reasons researchers tested it as a possible treatment (and arguably a possible preventative) for dementia. About 40 different flavonoids have been isolated, including ginkgetin, bilobetin and sciadopitysin. Isolated terpenes contain a number of ginkgolides and diterpenes, especially ginkgolides A, B and C together with Bilobalid. It is thought that there are two main responsible groups of active ingredients for medical effects Ginkgo biloba: lactones terpenic and ginkgo flavone glycosides, which ginkgo is present at different concentrations. Tebonin has several mechanisms of action. Vasoregulatory activity of the arteries, capillaries and veins (increased blood flow); Antagonism of Platelet Activating Factor (PAF); Homeostasis of inflammation and oxidative stress; and prevent damage to the cell membrane caused by free radicals; and modulation of neurotransmission. The most important substances are flavonoids (ginkgo flavonglycosides) and terpenoids (ginkgolides and bilobalides). Ginkgo compounds act as radical scavengers to varying degrees. Possible side effects of ginkgo biloba (Tebonin) include: Dizziness Nausea Vomiting Restlessness Diarrhea Headaches Stomach ache It is Contraindicated before surgery and after surgery. Gingko may increase the risk of bleeding associated with surgery. it is also not recommended for use during pregnancy or breastfeeding. Patients with circulatory disorders or those taking anticoagulants such as aspirin may experience side effects after taking ginkgo. As with any drug, precautions are needed to prevent drug interactions and other risks. Even ibuprofen in combination with gingko can increase the risk of internal bleeding. Avoid Using Selective serotonin reuptake inhibitors, antidepressant, and Gingko as it inhibits monoamine oxidase, reducing the effectiveness of the medications. The combination of both can also increase the risk of serotonin syndrome. Gingko may also exaggerate good and bad effects of another type of antidepressants as inhibitors of monoamine oxidase (MAO) inhibitors. Tebonin is not suitable for people under 18 years. Tebonin should be taken for at least two months before its benefit is assessed. The first benefits can be seen after two weeks and can improve with prolonged use. Take one Tebonin 120 mg tablet daily with some liquid (preferably water) with or without food. For more intensive use take 2 tablets daily. The doses range of Gingko from 80 to 720 mg/day for periods of 2 weeks to 2 years.

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Arinac Forte Tablet: Uses, Side Effects, Dosage etc

Arinac Forte and Advil are the brand names for the combination of two drugs i.e., Ibuprofen and Pseudoephedrine. Ibuprofen is a propionic acid derivative, a nonsteroidal anti-inflammatory drug with anti-inflammatory, analgesic, and antipyretic properties. It has fewer side effects than other NSAIDs, but its anti-inflammatory properties are weaker. Pseudoephedrine is an over-the-counter nasal decongestant for local application, but it can be used on the oral route, but its effect is not as good as Locally. Pseudoephedrine should be used with caution in diabetes, hypertension, hyperthyroidism, susceptibility to close-angle glaucoma, ischemic heart disease, and prostatic hypertrophy. Brand Names: Arenic Forte And Advil Manufacturer: Abbott LTD Active Ingredients of Arenic Forte Ibuprofen equal to 400 mg ibuprofen (NSAID) Pseudoephedrine HCL 60 mg Nonsteroidal anti-inflammatory drugs Active Ingredients Of Advil ibuprofen equal to 200 mg ibuprofen (NSAID) Pseudoephedrine HCL 30 mg Arinac Forte Uses Arinac Forte is used to treating inflammations as well as pain. Arinac Forte is used for Nasal Congestion. It acts as a nonsteroidal anti-inflammatory drug (NSAID) that controls hormones in the body, which cause pain and inflammation. It thus offers relief from several problems like A toothache, Fever and Pain Rheumatoid arthritis Osteoarthritis A Headache, Arthritis, Pain in the back, Other types of minor injuries and menstrual cramps. Mechanism Of Action Of Arinac Forte Arinac forte is the combination of Two Active Ingredients, i.e., Ibuprofen and Pseudoephedrine. Ibuprofen is a non-selective inhibitor of cyclooxygenase, an enzyme that interferes with the synthesis of prostaglandins via the metabolism of arachidonic acid. Its pharmacological effects are believed to be due to the inhibition of cyclooxygenase-2 (COX-2), which reduces the synthesis of prostaglandins involved in mediating inflammation, pain, fever, and inflammation. ‘swelling. The antipyretic effects may be due to an impact on the hypothalamus leading to an increase in peripheral perfusion, vasodilation, and subsequent heat dissipation. Inhibition of COX-1 is thought to cause some side effects of ibuprofen, including gastrointestinal ulceration. Ibuprofen is administered as a racemic mixture. The R enantiomer undergoes a significant conversion to the S enantiomer in vivo. The S enantiomer is believed to be the most pharmacologically active enantiomer. Pseudoephedrine is an agonist of α- and β-adrenergic receptors. Activation of Beta-adrenergic receptors in the nasal mucosa causes vasoconstriction and reduces congestion. The activation of β-adrenoceptors relaxes the smooth bronchial musculature. Pseudoephedrine also acts on the norepinephrine transporter SLC6A2, which promotes the release of norepinephrine stored in the neuronal synapse. In addition to the drug-induced direct activation, this leads to the activation of postsynaptic adrenoceptors. Avoid Arinac Forte if- You are allergic to any substance that is present in Arinac Forte. You have recently had a bypass operation. You have heart disease and risk suffering from a stroke or heart attack. Even those who do not have heart problems are likely to suffer a stroke or a heart attack because of the prolonged use of Arinac Forte. Arinac forte Interaction Avoid this medicine with the following drugs as it may cause side effects or may decrease the impact of Arinac forte. Tell your healthcare provider about the various other medications and supplements you are using so that doctors can prevent drug interactions. Aspirin Corticosteroids Lithium drugs Methotrexate Quinolone antibiotics Cyclosporine Mifepristone Quinidine Selective serotonin-reuptake inhibitors (SSRIs) Cardiac glycosides Contraindications: Arenac Forte is Contraindicated in the case of Asthma, Coronary Artery Disease, And Gastrointestinal Bleeding. The chance is higher if you are 60 or older or taking anticoagulant drugs. Ibuprofen present in Arinac Forte May Causes Allergic Reactions Like hives, facial swelling, asthma (wheezing), shock, skin reddening, rash, and blisters. It is also Contraindicated in Pregnancy. Side Effects Related To Arinac Forte The most common side effects of using Arinac Forte are Stomach Upset, Heartburn, Nausea and Vomiting, Ringing or buzzing in the ears, and Nervousness. While Rare Side Effects Include Abdominal discomfort, Constipation, Decreased urine output, Yellow-coloured eyes or skin, Skin Rash, Loss of appetite, and Running Nose. Arinac Forte Dosage Arinac forte should be taken with food to avoid stomach upset. Use it as directed by your physician. Don’t exceed the recommended dose. Try to take it at a fixed time of the day to maintain a consistent level in the blood. The recommended dose of Arinac forte is one tablet every 4 hours, or use it when necessary. Don’t exceed 1200 mg daily. Related Articles Arthrozene Review: Is this Arthritis Supplement work?  Heal n Soothe Review: Is it worth it? Relief Factor Review: Is it worth it or a Scam? 

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Optalidon: Information You Need To Know

Optalidon is the brand name of the combination of two ingredients i.e Caffeine 25mg and Propyphenazone 175mg. Caffeine is a central nervous system stimulant of the methylxanthine class.Caffeine is considered the most commonly used psychoactive drug in the world. Propyphenazone is Non-steroidal anti-inflammatory drug, NSAID and is used in Analgesic, antipyretic and anti-inflammatory agent. Propyphenazone alone is rapidly absorbed. After a single oral dose of 220 mg, peak plasma concentrations of about 1.5-3.5 mg/l are attained at between 0.5 h and 1.2 h with a mean biological half-life of approximately 2.8 ± 0.6 h. Uses Of Optalidon: Optalidon is used in: Dysmenorrhoea,  Pain,  Rheumatoid arthritis,  Juvenile chronic arthritis,  Osteoarthritis,  Ankylosing spondylitis,  Fever, Acute arthritis,  Toothache,  Musculoskeletal pain,. Mechanism of action Of Optalidon   Caffeine is a central nervous system stimulant that occurs naturally in more than 60 plant species and is used in various foods, drinks and medicines. Caffeine stimulates the medullary, vasomotor and respiratory centers and promotes bradycardia, vasoconstriction and increased respiratory rate. Previously, it was believed that this effect is mainly due to the increase of intracellular cyclic 3 ‘, 5’-adenosine monophosphate (cyclic AMP) after the inhibition of phosphodiesterase, the enzyme that degrades cyclic AMP. Caffeine passes the blood-brain barrier that is supposed to separate the brain from the bloodstream. Once in the brain, caffeine blocks the action of adenosine, which plays an important role in energy transfer and sleep enhancement. Since adenosine acts as an autocoid, it inhibits the release of neurotransmitters from presynaptic sites, but increases the effect of norepinephrine or angiotensin, the antagonism of adenosine receptors promotes the release of neurotransmitters. This explains the stimulating effect of caffeine. The blockade of the adenosine A1 receptor in the heart results in an accelerated and pronounced “heartbeat” of the heart when caffeine is consumed. Propyphenazone is an NSAID derived from pyrazolone and related to phenazone. It has antipyretic and analgesic properties. Side effects of Optalidon Optalidon (caffeine + propyphenazone) may cause some side effects. Side effects are not common and sometimes very rare, but each medication has some side effects along with  beneficial effects: Propifenazone may cause myocardial infarction with low atrial rhythm Propifenazone may also cause side effects that are not listed here. During anxiety disorders, caffeine with bipolar disorder could worsen these conditions. Use carefully. There are concerns that caffeine can make bleeding worse. Caffeine can lead to irregular heartbeats in sensitive individuals. Caffeine, especially when taken in large quantities, can make diarrhea worse. People with epilepsy should avoid the use of high-dose caffeine. Caffeine intake can increase blood pressure in people with high blood pressure. Caffeine, especially when taken in large quantities, can make diarrhea worse and worsen IBS symptoms. Dosage and administration of Optalidon In adults: 1 to 2 tablets 1-3 times daily. In children older than 12 years: 1 tablet a day. Related Article : Important information about Aspirin 

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Your Baby Got Colic: Symptoms, Causes And Treatment

Colic is the excessive and frequent crying of a baby who appears to be in good health. It’s not a disease, hungry, wet, tired, hot or cold, but inexplicably miserable – pediatricians call it colic means your Baby Got colic. This is a common problem that affects up to one in five babies. It starts around the age of 2 weeks if your child is old (or later if prematurely), Colic has 3 three types to know Infant Colic or Baby Colic, renal colic (caused by kidney stones) and biliary colic (caused by gallstones). Symptoms Of Colic The following symptoms will occur in an otherwise healthy and well-nourished baby Or your baby got colic: Intense cries: The child cries intensely and angrily, and parents cannot do much to comfort them. The baby’s face turns red and red. Screaming episodes usually happen every day at the same time – usually late afternoon or evening. Episodes can last from a few minutes to longer periods. Crying usually starts suddenly and for no apparent reason. Different intensities: In some infants, the symptoms are mild and the baby can only experience periods of agitation. Sleep can be irregular and interrupted by crying. Modified posture: Fists may be tight, abs tight, knees bowed and back arched Diet: The diet can be interrupted and irregular with intense screaming episodes. However, the amount the baby eats every day is not reduced. Wind: During intense crying episodes, the baby can let the wind through.   Causes of colic The cause or causes of colic are unknown, but a number of theories have been suggested. These include indigestion, closed wind or a temporary sensitivity of the intestine to certain proteins and the sugars found in breast milk and formula. If your baby got colic, this may be due to the following reasons Hormones that cause stomach pain or a difficult mood A digestive system growing with muscles that often spasm Gas Hypersensitivity or overstimulation caused by light, sound, etc. Immature nervous system A low birth weight baby It has also been suggested that colic can only be at the very end of normal crying in babies. Colic also occurs in boys and girls, both in babies who are breastfed and those who are fed by the bottle. Treatment if your Baby Got Colic There is no proven cure for colic because there is no definite cause. Many treatments aim to reduce the intensity of crying and eliminate all the factors that could exacerbate it. The following list is some of the common things that are used to soothe crying when your baby has colic; Colic drops are the baby formula for colic if your baby got colic or was crying (colic drops contain simethicone help the best for the relief of additional gas symptoms by swallowing the air or certain foods/infant formula, gas bubbles in the intestine Lactase Drops: Lactase is another baby formula for colic it’s an enzyme that breaks down lactose into glucose and galactose. People with lactase deficiency in the gut may develop abdominal cramps and diarrhea after eating dairy products. Lactase helps prevent this. Probiotic Drops promote digestive health & support immune function. It may also help with occasional gas, diarrhea & constipation. Keeping your child is one of the most effective treatments. The more hours, even if they are not difficult, the less they are long at night. Put a bottle of warm water on your baby’s belly (make sure it’s not too hot). Breastfeeding mothers can reduce colic by ensuring that the baby gets each “that milk” good and not just “pre-milk” diet. Colic calm is a homeopathic remedy and is very effective if your baby got colic. Colic calm provides safe, gentle relief for discomfort from gas, stomach upset and colic. Colic Calm is the only gripe water that is an FDA-listed homeopathic medicine. Baby crabs may have an allergy or reaction to ingredients in their formula and may need to move on. Breastfeeding mothers may need to judge what they eat by keeping a food diary and crying. Place your baby’s belly on your lap as you gently move your legs to massage the abdominal area. Keep your baby standing as often as possible. Burp your baby often. Apart from these treatments, you can try home remedies if your baby got colic take a hot bath, fresh air, let the baby suck, make noise, create closeness. Related Article: Important Information Leucoderma

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Terbutaline: Uses, Mechanism, Side Effects, Dosage Information

Terbutaline is an agonist of beta-adrenergic receptors used for the prevention and resolution of bronchospasm in patients 12 years of age and older with asthma and reversible bronchospasm associated with bronchitis and emphysema. Terbutaline was approved by The Food and Drug Administration (FDA)  in 1974. Mechanism of action The pharmacological effects of terbutaline are at least partially due to stimulation by beta-adrenergic receptor intracellular adenyl cyclase, the enzyme that catalyzes the conversion of adenosine triphosphate (ATP) into ciclosporin-3 ‘, 5’ adenosine monophosphate (c-AMP). Elevated c-AMP levels are associated with bronchial smooth muscle relaxation and the inhibition of mediator release from the immediate hypersensitivity of cells, particularly mast cells. Side effects The most common side effects that can occur with terbutaline are: Nausea, Vomiting, Weakness, Nervousness Tremor A headache Fast heartbeat Flushed feeling, Sweating, Pain at the injection site, Anxiety, Shortness of breath, Chest discomfort, Shortness of breath, Chest discomfort, Dizziness, Drowsiness, Palpitations, While Serious side effects  may include : Hallucinations Interaction With other drugs When taken with terbutaline, certain drugs can worsen the side effects ofthis drug. Examples of these drugs include: Amitriptyline Doxepin Phenelzine Selegiline Metoprolol Labetalol Furosemide Hydrochlorothiazide Terbutaline during pregnancy It should not be used to stop or prevent premature labor in pregnant women, especially in women who are not hospitalized. Terbutaline caused severe side effects, including death, in pregnant women who took the drug for this purpose. Terbutaline also caused serious side effects in newborns whose mothers took the drug to stop or prevent childbirth. Precautions Consult your doctor before using Terbutaline if you have Thyroid problem Diabetes Heart disease High blood pressure Glaucoma Low levels of potassium in your blood. had an allergic reaction to a medicine. Dosage for terbutaline The recommended dose in adults for the treatment of bronchospasm for asthma, emphysema or bronchitis is 2.5 to 5 mg, 3-4 times daily, and about 6 hours apart while awake. The maximum dose is 15 mg/day. The recommended subcutaneous dose (under the skin) is 0.25 mg every 15-30 minutes for two doses. The maximum dose is 0.5 mg within 4 hours. The recommended dose for the inhaler is 2 puffs every 4 to 6 hours. The premature labor dose is initially 2.5 to 10 mcg/min with intravenous infusion, then the dose increases every 10 to 20 minutes. The typical effective dose is 17.5 to 30 mcg/min. The treatment should not exceed 72 hours. Overdose Symptoms of a Terbutaline overdose may include Chest pain, Fainting or dizziness, Vomiting, Nervousness, Excessive tiredness or weakness, Dry mouth,Pounding, fast, or irregular heartbeat, Headache, Uncontrollable shaking of a part of the body, Difficulty falling asleep or staying asleep, Seizures. If these symptom occur contact your GP. Missed Dose If you miss a dose of this drug take it as soon as you remember. But if it’s almost time for your next dose, skip the missed dose and continue with your regular medication schedule. More at DrugsBank

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CDC Plans Session On Public Health Response to a Nuclear Detonation

In the wake of this week’s barbaric allegations of who has the biggest red button on their desk, Thursday’s alarm from the Centers for Disease Control and Prevention was more than a little on the nose. With the growing likelihood of a real nuclear war between North Korea and the United States, the CDC is preparing to train health professionals and others on how public health would respond to a nuclear detonation. The CDC has announced that it will organize a big round, a course, on this topic. The target group: physicians, nurses, epidemiologists, pharmacists, veterinarians, certified health education specialists, laboratory scientists and others. The event will take place on the 16th of January. A spokesperson for the agency said the event has been planned for months as CDC officials participated last April in a radiation / nuclear incident exercise led by the Federal Emergency Management Agency. Kathy Harben said in an e-mail. “The CDC participants felt that this would be a good way to discuss public health preparedness and share resources with states and other partners, and state and local partners have shown interest in the issue over time,” he said. Nevertheless, the timing of the announcement was scary, right after the successive threats between North Korean leader Kim Jong Un and President Donald Trump. “Join us in this grand rounds session to find out which public health programs at federal, state and local level are preparing for a nuclear detonation,” he urged the CDC e-mail to send people over to one of the the mailing lists of the agency. “Learn how the planning and preparation efforts for a nuclear detonation are similar and different to those of other emergency response measures.” Almost every month, the CDC organizes large rounds on issues such as birth defects, tick-borne diseases, and sodium reduction. In March 2010, large rounds of preparation for radiological and nuclear disasters were offered. The director of the CDC tells the staff “there are no forbidden words”, although the report does not refute The titles of some of the discussions that will form the session are sufficient to pause, including “Prepare for the Unthinkable” and “Roadmap for the Preparation of Radiation”. Equally worrying is the picture of a cloud of cloudy mushrooms on the website announcing the event. “While nuclear detonation is unlikely, it would have devastating consequences and limited time to take critical protective measures,” the agency said. “Despite the fear of such an event, planning and preparation can reduce deaths and illnesses.” “For example, most people are unaware that on-site protection is critical for at least 24 hours to save lives and reduce radiation exposure, although federal, state, and local authorities will lead the effort Public health will play a key role in the response. ” The event will be broadcast live from the CDC headquarters in Atlanta and released a few days later in the large round file page.

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