Best Anti Aging Supplements: What Works & What Doesn’t?

As we age, our bodies undergo various changes, and our skin, hair, and nails begin to show signs of wear and tear. However, with advancements in science and medicine, there are now several anti-aging supplements available that claim to help slow down the aging process and promote youthful-looking skin, hair, and nails. From collagen to antioxidants, these supplements are packed with essential nutrients and ingredients that can help improve your overall health and well-being. In this article, we will take a closer look at some of the best anti-aging supplements available on the market today and explore their potential benefits. Whether you’re looking to reduce wrinkles, improve skin elasticity, or enhance your overall health, we’ve got you covered. Here are some ingredients that have been scientifically proven to help reduce the visible signs of aging and promote overall health.

Coenzyme Q10 (CoQ10)

Coenzyme Q10 is a powerful antioxidant [1] that protects our cells from oxidative stress and free radicals, which can cause premature aging. CoQ10 is naturally produced in our bodies, but its production decreases with age. Supplementing with CoQ10 can help reduce the appearance of wrinkles, improve skin texture, and promote overall skin health [2]. CoQ10 can be found in supplement form and foods like fatty fish, organ meats, and whole grains.

Vitamin C

Vitamin C is another potent antioxidant [3] that protects our skin from the damaging effects of UV radiation and free radicals. It also plays a critical role in collagen synthesis, which helps improve skin elasticity and firmness.[4] Supplementing with vitamin C can help reduce the appearance of fine lines and wrinkles, improve skin texture, and brighten the complexion. Vitamin C can be found in supplement form and foods like citrus fruits, berries, and leafy greens.


Collagen is the most abundant protein in our body and plays a critical role in maintaining the health of our skin, hair, nails, and joints. As we age, collagen production decreases, leading to wrinkles, sagging skin, and joint pain. Supplementing with collagen can help improve skin elasticity and hydration, reduce wrinkles, and alleviate joint pain [5]. Collagen can be found in supplement form and foods like bone broth, meat, fish, and egg whites.


Resveratrol is a polyphenol found in red wine, grapes, and berries. It has been shown to have anti-aging properties by reducing oxidative stress, inflammation, and DNA damage. Supplementing with resveratrol can help improve skin elasticity and firmness, reduce the appearance of fine lines and wrinkles, promote overall health, and improve lifespan [6].

Best Resveratrol Supplements

Omega-3 Fatty Acids

Omega-3 fatty acids are essential fatty acids our body cannot produce on its own. They are critical for maintaining healthy skin, hair, and nails, reducing inflammation, and improving overall health. Supplementing with omega-3 fatty acids can help improve skin texture, reduce inflammation [7], protect skin from UV rays [8] and promote overall health. Omega-3 fatty acids can be found in supplement forms and foods like fatty fish, flaxseeds, and walnuts.


Retinoids are a form of vitamin A that has been shown to have anti-aging properties [9] by increasing collagen production [10] and improving skin texture. They also help reduce the appearance of fine lines and wrinkles and improve skin tone and pigmentation. Retinoids are available in prescription and over-the-counter forms and should be used under the guidance of a healthcare professional. 


NMN, or nicotinamide mononucleotide, is a molecule naturally produced in the body and is involved in producing a molecule called NAD+, which is vital for energy metabolism and cellular function. Some studies suggest that NMN may have anti-aging properties due to its role in NAD+ metabolism.

Research has shown that NAD+ levels decline with age, which may contribute to the aging process. NMN has been shown to increase NAD+ levels in mice, and some studies suggest that it may have similar effects in humans. In a recent clinical trial, researchers gave NMN supplements to healthy elderly individuals. They found that it improved insulin sensitivity and blood pressure measures, both associated with aging [11]. 

While there is some promising research on the potential anti-aging properties of NMN, more studies are needed to understand its effects in humans fully. It’s also important to note that the quality and purity of NMN supplements can vary, so it’s important to choose supplements from reputable companies that have been third-party tested for purity and potency.

Best NMN supplement Brands


Probiotics are live bacteria that help improve gut health, which has been linked to overall health and skin health. Probiotics can help reduce inflammation [12], improve skin hydration, and enhance the skin’s natural barrier function. Probiotics can be found in supplement form and fermented foods like yogurt, kefir, and sauerkraut.

Read Different Probiotics Brand Reviews

Green Tea Extract

Green tea extract is also a potent antioxidant with anti-aging properties [13]. It helps protect the skin from UV damage. Green tea extract also helps improve skin texture, stops the rise of fluorescent markers of collagen aging [14], and reduces the appearance of fine lines and wrinkles. Green tea extract can be found in foods and beverages like tea, matcha, and supplements.

Hyaluronic Acid

Hyaluronic acid is a naturally occurring substance in our body that helps maintain skin hydration and firmness [15]. As we age, the production of hyaluronic acid decreases, leading to dry, dull, and sagging skin. Supplementing with hyaluronic acid can help improve skin hydration, reduce the appearance of fine lines and wrinkles, and improve overall skin health. This ingredient can be found in supplements and skincare products like serums and creams.

The top researched-based and scientifically proven anti-aging supplement ingredients include collagen, CoQ10, vitamin C, resveratrol, omega-3 fatty acids, retinoids, NMN, probiotics, green tea extract, and hyaluronic acid. These ingredients have been shown to have anti-aging properties by reducing inflammation, protecting against oxidative stress, and promoting overall skin health. Incorporating these supplements into your daily routine can help you look and feel your best as you age.

What To Look For When Choosing supplements?

When choosing anti-aging or any other supplements, it’s important to look for products that contain high-quality, researched-based, and scientifically proven ingredients. Here are some tips on what to look for when choosing supplements:

  1. Look for supplements made by reputable companies with a good track record of safety and efficacy.
  2. See if the product is third-party tested or not because it is a crucial factor to consider when selecting a supplement. Third-party testing is when an independent laboratory tests the supplement to verify its potency, purity, and safety. This can give consumers an added layer of confidence that the supplement contains the ingredients it claims to and is free of contaminants or other harmful substances.
  3. Check the label to ensure the supplement contains the researched-based and scientifically proven ingredients you’re looking for.
  4. Make sure the supplement contains the recommended daily dose of each ingredient.
  5. Choose supplements that are free of harmful additives, fillers, and preservatives.
  6. Consider your individual needs and consult a healthcare provider to determine which supplements are right for you.

By following these tips, you can help ensure that the anti-aging supplements you choose are safe and effective in promoting overall health and reducing the visible signs of aging.

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