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Depo Provera: Uses, Side Effects, Dosage & FAQs

Depo Provera is a brand name for a type of birth control medication that contains medroxyprogesterone acetate. It is given as an injection, usually in the arm or buttock, once every three months to prevent pregnancy. The progestin in Depo Provera thickens cervical mucus, making it harder for sperm to reach an egg. It also prevents ovulation, which is the release of an egg from the ovaries. Depo Provera is a highly effective form of birth control and is often used by people who cannot or do not want to use other forms of contraceptive methods, such as condoms or birth control pills. Depo-Provera generally inhibits ovulation and prevents the ovaries from releasing an egg. Depo-Provera also thickens cervical mucus to prevent sperm from entering the egg. It’s also called Depo-Shot. It’s an injection that a doctor makes in your arm or buttocks. Each injection will work for 12 to 14 weeks, but you should receive the injection every 12 weeks. Depo Provera is a safe, convenient, and private contraception method that works very well if you always get it on time. Mechanism of Depo Provera A progestin prevents you from becoming pregnant by preventing ovulation. If there is no egg in the tube, pregnancy is not possible. It also works by making the cervical mucus thicker. If cervical mucus is thicker, sperm can no longer occur. And if the sperm and the egg can not meet, the pregnancy can not take place. Contraindications Depo Provera is contraindicated for those who have: Liver disease Blood clots Unexplained vaginal bleeding Breast cancer osteoporosis Pregnancy Pros And Cons Of Depo Provera Pros It’s very Convenient The depo shot is 97-98% Effective it doesn’t interrupt sex No daily contraceptives pill-taking like I Pill and unwanted 72. it’s not affected by other medicines Each shot lasts for either 8 or 13 weeks it’s safe to use while you’re breastfeeding it’s an option if you can’t use estrogen-based contraception. it may reduce heavy, painful periods and help with premenstrual symptoms for some women you don’t have to remember to take a pill every day. Cons It does not protect against sexually transmitted infections. You may have spots between periods. Periods can become irregular. Remember to schedule an injection every three months. It is not generally recommended for long-term use. Depo Provera Side Effects Common Side effects of depo provera can include Nausea, Weight gain, Headaches Stomach cramping or pain, Dizziness, Bloating, Mood swings, Irritability, Drowsiness, Breast tenderness and Hair loss Acne Your periods may become more irregular, heavier, shorter, lighter, or stop altogether. Serious Side effects of Depo Provera include; Worsening depression, Bone pain, Changes in sexual interest or ability, Swelling of the ankles or feet, Persistent nausea or vomiting, dark urine, unusual changes in vaginal bleeding severe abdominal pain, Seizures Unusual weakness or tiredness, Yellowing eyes or skin. Dosage Depo Provera is administered by injection and injected into the muscle every 3 months. One injection of 150 mg intramuscularly. It must be administered within the first five days of a normal menstrual cycle. Frequently Asked Questions 1. What is Depo Provera? Depo Provera is a contraceptive injection for women containing the progestin hormone. This is the brand name for medroxyprogesterone acetate. Depo-Provera is given by injection every three months. 2. How fast does it work? Depo-Provera starts acting as a contraceptive method immediately after the first injection if you receive it within your period’s first 5 days. 3. How should I take Depo-Provera? Your doctor will give you Depo-Provera as an injection into your muscle (intramuscular injection). The injection takes place every 3 months in the buttocks or the arm. After 3 months, you should consult your doctor for the next injection to continue to protect you from pregnancy. 4. How well does it work? Depo Provera is an extremely effective contraceptive method when administered every three months (99.8% effectiveness). Approximately one in twenty (six percent) women become pregnant with Depo Provera. 5. What did I notice after taking Depo Provera? Some women have irregular or persistent bleeding, especially in the first three to six months. This is safe for your body, and there are pills to stop this when it happens. 6. Can I get pregnant after dropping the Depo provera injection? You can get pregnant 3 to 4 months after your last injection. However, some women need at least one or two years to get pregnant after having stopped this contraception type. This delay does not seem to be related to the useful life of the plan. 7. How does Depo Provera work? It prevents pregnancy by preventing the ovaries from releasing an egg every month. There are also changes in the lining of the uterus. 8. What is the level of security when shooting with Depo Provera? It is safe for most people, but all medications have risks and side effects. Your doctor or nurse will help you determine if the vaccine is right for you. 9. Is it safe to use Depo Provera during breastfeeding? Yes, it is safe to use contraceptives during breastfeeding. This should not affect the amount of milk it produces and will not harm your baby. In fact, the vaccine is an excellent method if you are breastfeeding and do not want to get pregnant. 10. What if I forget to have my depo shot on time? It depends on your delay. You can receive your follow-up vaccinations as soon as 10 weeks after your last injection or up to 15 weeks after your last injection. However, if you have been vaccinated for more than 15 weeks after the last injection, you must use a contraceptive backup method, such as a condom, during the first week of filming. Learn more about Medicine Brands

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Cefspan Tablet Uses, Side Effects, Dosage And FAQs

Cefspan tablet (Generic: Cefixime) is a potent broad-spectrum antibiotic manufacture by Barrett Hodgson PVT Ltd. This prescription medication is harnessed to effectively combat a range of conditions caused by specific bacterial infections. While it holds remarkable potential in addressing various health concerns, it is crucial to understand its uses, dosages, potential side effects, and precautions. Cefspan tablet is an antibacterial agent, indispensable in treating various medical conditions. Among its notable uses are urinary tract infections, throat infections, bacterial lung infections, and certain ear infections. It’s essential to recognize that Cefspan’s efficacy is restricted to bacterial infections and unsuitable for combating viral ailments such as colds or the flu. Available in diverse forms and strengths, Cefspan caters to various dosage needs: Cefspan 200 mg Capsule Cefspan 400 mg Tablet Cefspan 100 mg Syrup Cefspan 200 mg Syrup Cefspan Tablet Uses Cefixime, the active ingredient in Cefspan, exhibits remarkable effectiveness in addressing multiple infections, including but not limited to: Infections of the middle ear Laryngitis Bacterial pneumonia Tonsillitis Throat infections Bronchitis Moreover, the Cefspan tablet finds utility in treating: Urinary tract infections Acute bacterial bronchitis in patients with chronic obstructive pulmonary disease (COPD) Gonorrhea Cefspan Tablet Dosage Guidelines Administered orally, Cefspan tablet or liquid form requires once or twice daily intake for a duration ranging from five to fourteen days. For adults, the typical recommended dose for conditions such as tonsillitis, otitis media, pharyngitis, and urinary tract infections is either a single daily dose of 400 mg or a divided dose of 200 mg every 12 hours.  It is paramount to adhere to your healthcare provider’s recommended dosage, as modifying the treatment regimen without medical guidance is not advised. Precautions Before commencing Cefspan treatment, a comprehensive discussion with your healthcare provider is essential to cover aspects such as: Medical history Allergies, especially to cephalosporin-class drugs, food, or chemicals Current prescription and non-prescription medications in use Overall health status Cefspan tablet Side Effects While Cefspan offers potent infection-fighting capabilities, it can trigger specific side effects. Common, reversible side effects include: Nausea Diarrhea Stomach pain Gas Heartburn Vomiting If these symptoms become severe, seeking prompt medical attention is crucial. Additionally, be vigilant about serious side effects like: Difficulty in breathing Rash Itching Stomach cramps Hives Swelling of the face, tongue, or throat Wheezing Mechanism of Action Cefixime hinders the multiplication of bacteria by impeding the formation of their protective cell walls. These walls are indispensable for safeguarding bacteria and maintaining the structural integrity of bacterial cells. Devoid of a functional cell wall, most bacteria cannot survive, rendering Cefspan’s mechanism of action a potent means of combating bacterial infections. Frequently Asked Questions: Question: Is it Safe with alcohol? The interactions between Cefspan and alcohol remain uncertain. Prior consultation with a healthcare professional is recommended before concurrent use. Question: Is it habit-forming medicine? No instances of habit-forming tendencies have been reported with Cefspan. Question: Is Cefspan (cefixime) safe during pregnancy? While animal studies reveal no fetal harm, limited data from pregnant women is available. Consultation with a healthcare provider is essential to weigh potential benefits and risks. Question: Is Cefspan (cefixime) safe while breastfeeding? Limited studies on breastfeeding women are available. Assessing potential risks and benefits is crucial before usage. Question: Which medicines or supplements interact with Cefspan (cefixime)? Cefspan may interact with other drugs, leading to side effects. Notable interactions include: Probenecid, which may increase cefixime blood levels Combination with aminoglycosides, intensifying bacterial destruction and potentially affecting kidney function Exenatide potentially delaying cephalosporin absorption. Interference with live bacterial vaccines (e.g., typhoid vaccine) Question: What happens if you miss a dose? If a dose is missed, take it promptly upon recall. However, avoid doubling doses to compensate for a missed one. Question: What happens with an overdose? In case of severe symptoms or loss of consciousness, seek immediate medical attention. Otherwise, contact a poison control centre. Question: What should I avoid when I take this medicine? Antibiotics like Cefspan can induce diarrhea, potentially signalling new infections. Contact your doctor if severe diarrhea occurs. Avoid antidiarrheal drugs without medical approval. Question: How to store cefixime (Cefspan)? Store Cefspan in a closed container at room temperature, away from heat, moisture, and direct light. Unused oral fluid should be refrigerated or stored at room temperature. Discard unused drugs after 14 days, and keep them out of children’s reach. Incorporating Cefspan tablet into your healthcare regimen can offer effective solutions for various bacterial infections. However, a prudent approach involves detailed consultations with healthcare professionals to determine the appropriate usage, dosage, and management of potential side effects. Your well-being is paramount, and Cefspan is a valuable ally in your fight against bacterial infections. More Brands; Co-Amoxiclav: Uses, Side Effects, Dosage Rigix (Cetirizine): Uses, Side Effects, Dosage Sulvorid 25 and 50mg: Uses, Side Effects, Dosage Citanew Tablet: Uses, Side Effects, Dosage Osnate D tablet: Uses, Side Effects, Dosage Leflox Tablet: Uses, Side Effects, Dosage Gonadil F: Uses, Side Effects, Dosage More Pakistani Brands

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Faslodex (Fulvestrant): Uses, Side Effects, Dosage, FAQs

Faslodex is the brand name for Fulvestrant. Faslodex belongs to a class of hormone therapy drugs. It fights cancer as an “estrogen receptor Antagonist.” Faslodex is a liquid given once a month as an injection into a muscle, usually at your doctor’s office. AstraZeneca manufactures Faslodex for the treatment of metastatic hormone receptor-positive breast cancer. Faslodex Uses Faslodex injection is used to treat breast cancer spread to other parts of the body in postmenopausal women. It is used in the treatment and prevention of the following conditions. It is used in Hormone receptor (HR)-positive advanced breast cancer, women who have gone through menopause and whose disease has progressed after antiestrogen therapy. It is also used in Hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative advanced breast cancer, who have gone through menopause and have not been previously treated with endocrine therapy. It is used in combination with palbociclib (Ibrance)  or abemaciclib in treating HR-positive, HER2-negative advanced breast cancer or breast cancer that has spread to other parts of the body (metastatic). Faslodex does not work on hormone-receptor-negative breast cancer. Mechanism Of Action The female sex hormones estrogen and progesterone stimulate the growth of certain breast cancers. These breast cancers are called hormone-sensitive or hormone receptor-positive. Drugs that block these hormones’ actions can slow down or stop the growth of breast cancer cells. Faslodex prevents estrogen from reaching cancer cells by blocking estrogen receptors and reducing the number of cancer cell receptors. It binds, blocks, and increases the degradation of the estrogen receptor. Faslodex Side Effects The most common side effects of Faslodex are: Nausea Vomiting Diarrhea Hot flashes constipation Stomach/abdominal pain injection site pain sore throat back pain headache Some women may have other side effects while taking Faslodex: Dizziness Bone/joint pain Swelling loss of appetite Dry skin. Sweating Sleeping problems Nervousness/anxiety Precautions Before using this injection, tell your doctor or pharmacist if you are/have Allergic to it; or if you have any other allergies. Faslodex may make you dizzy. Do not drive, use machinery, or do any activity that requires alertness until you can safely perform such activities. Liver disease, bleeding problems, and low platelet counts (thrombocytopenia). Pregnant or plan to become pregnant. It would help if you did not become pregnant while using fulvestrant. Fulvestrant may harm an unborn baby. Do not breastfeed while taking this medication. Contraindications Faslodex Injection is contraindicated in patients with known hypersensitivity to the drug or any of its components. Hypersensitivity reactions, including Angioedema Urticaria and Redness of the face, Other symptoms include Dizziness, A headache, shortness of breath and Anxiety. Dosage The recommended dose is 500 mg by intramuscular route in the buttocks. Inject it slowly for 1 to 2 minutes. There are two injections of 5 ml each, one in each buttock on days 1, 15, and 29, then once a month. When used in combination with palbociclib (Ibrance), the recommended dose is 500 mg intramuscularly slowly in the buttocks. Inject it slowly for 1 to 2 minutes. There are 2 injections of 5 ml on days 1, 15, and 29, and once a month since then. The recommended dose of palbociclib is a 125 mg capsule once a day for 21 consecutive days, followed by a rest period of 7 days, including a full cycle of 28 days. Palbociclib should be taken with a meal. Frequently Asked Questions (FAQS) 1. What is the Faslodex Injection? It is the Brand/Trade name for Fulvestrant. It belongs to a class of hormone therapy drugs.  It fights cancer as an “estrogen receptor down-regulator.” 2. What Faslodex is used for? Faslodex Injection treats certain types of breast cancer in post-menopausal women that have spread to other areas of the body. 3. How to Use it? This medicine is slowly injected into the gluteal muscle as directed by your doctor. It is usually given every 2 weeks for the first 3 doses and then monthly. You will be asked if you want to give your dose in one or two injections. 4. What happens if I overdose on Faslodex? Since a healthcare professional administers this drug in a medical setting, it is unlikely to overdose. If an overdose is suspected, contact a poison control center or the emergency room immediately. 5. What other drugs will affect Faslodex? Tell your doctor about all your other prescriptions and over-the-counter medications, especially: warfarin, Coumadin, Jantoven. According to a study published in the Journal “Of British Pharmacological Society,” the addition of fulvestrant to anastrozole treatment decreased the trough anastrozole concentration. This is not a complete list of drug interactions. Consult your doctor before using other medications with Faslodex. 6. What are the side effects of Faslodex Injection? Common side effects associated with the use of this medicine include;  nausea, vomiting, diarrhea, hot flashes, constipation, stomach/abdominal pain, sore throat, back pain, headache, and injection site pain. Check more above. 7. Is Faslodex a form of Chemotherapy? Faslodex is a targeted therapy that keeps estrogen from forming more cancer cells. 8. Is Faslodex Safe to use during Pregnancy? You should not receive fulvestrant if you are pregnant. Avoid becoming pregnant for at least one year after stopping this medication. The use of fulvestrant during pregnancy can harm the fetus. Use effective contraception to prevent pregnancy using this medication and at least one year after the treatment. 9. Is Faslodex safe while breastfeeding? It is not known if Fulvestrant enters breast milk or could harm the baby. You should not receive fulvestrant while breastfeeding. Avoid breastfeeding for at least one year after stopping this medication. Ask your doctor. 10. Can I drive or use machines after taking Faslodex? This medicine may make you feel dizzy. Do not drive, operate machinery, or perform activities requiring alertness until you can safely perform them. 11. How is it stored? Supplied in two 5 ml clear glass containers (type 1), each containing 250 mg / 5 ml Intramuscular solution, with a tamper-evident cap. 12. Who can not take this medicine? Do not use this medicine if you are allergic to fulvestrant or any of the other

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Ebola vaccine shows high efficacy rate in outbreak

An experimental vaccine against Ebola epidemics in the Democratic Republic of Congo (DRC) is delivering promising results, said a new World Health Organization (WHO) study on Friday. The vaccine showed an efficiency of 97.5%. In August last year, 93,965 people at risk were vaccinated. Only 71 of them developed Ebola. Of the 71 people, nearly 56 had symptoms within 10 days of receiving the vaccine. It takes about 10 days for the vaccine to develop immunity to the virus. The other 15 people contracted the virus ten days after vaccination. “No deaths were reported among vaccinees who developed Ebola with onset 10 or more days after vaccination. These early results confirm previous observations of high efficacy of (rVSV-ZEBOV-GP) Ebola vaccine against the disease,” the study said. Health officials are taking the ring vaccine strategy to vaccinate only the most frequently infected individuals to test the Ebola vaccine. The procedure was first adopted to prevent the spread of smallpox. “The ring vaccination strategy is a highly efficient delivery strategy for Ebola vaccines during outbreaks,” the WHO maintained. The frequent Ebola epidemics have created a major health problem worldwide. During the recent outbreak in the Democratic Republic of the Congo (DRC), approximately 1,206 confirmed and probable cases of Ebola infection have been reported. The virus killed dozens of people in the northern provinces of Kivu and Ituri. Fearing an Ebola outbreak, the European Union, Russia and China are developing vaccines against the Ebola virus. There are currently more than 15 vaccines in various stages of testing. According to the WHO statement issued last year, pharmaceutical companies have committed to increasing their production capacity once the vaccine has passed the required tests. “This could be the fastest vaccine in history.” Despite the growing number of Ebola cases in the Democratic Republic of the Congo, senior WHO officials refused on Friday to declare the epidemic a global health emergency. “It was the view of the Committee the ongoing Ebola outbreak in North Kivu, and Ituri provinces of the Democratic Republic of the Congo does not constitute a Public Health Emergency of International Concern (PHEIC),” said Robert Steffen, chair of the WHO committee convened in an emergency declaration.

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LSD (Lysergic acid diethylamide): Uses, Hazards, Effects, FAQs

LSD or lysergic acid diethylamide is a synthetic chemical and a psychedelic drug derived from a chemical found in the rye fungus. It is best known for its use during the counterculture of the 1960s, and the resulting ban gave him a rather negative reputation. Psychedelics are drugs that can induce an altered state, perhaps best described as a dream state, for a number of minutes or hours, depending on the specific psychedelic. LSD is a white crystalline substance with no odor. However, LSD is so powerful that a low dose of a pure drug is so effective that it is virtually invisible. As a result, it is usually diluted with other materials. The most common form of LSD consists of drops of dried LSD solution on gelatin sheets, pieces of absorbent paper or pieces of sugar that release the drug when ingested. It is also sometimes sold in liquid, tablet or capsule form. In 1938, Albert Hofmann, a Swiss scientist, synthesized LSD in his laboratory in Zurich, Switzerland. Unexpectedly, he discovered his hallucinogenic effects in 1943, when a small amount came into contact with his skin. LSD is an extremely powerful hallucinogen with tremendous therapeutic, spiritual and cultural potential. It is also Known as “acid” and with many other names, It is sold on the street in the form of small tablets (“microdots”), capsules or jelly (“windows”). Sometimes LSD is added to paper towels, which are then divided into small squares decorated with drawings or comic characters. Sometimes it is sold in liquid form. But no matter what form you get, It takes the user to the same place, a serious disconnect from reality. Users of this drug called a “trip” an LSD experience, which typically lasts about twelve hours. When things go wrong, what happens often, we talk about “bad journey”, another name for a living hell. Chemical Structure Mechanism It stimulates the production of serotonin in the cortex and deep brain structures by activating serotonin receptors. These receivers help visualize and interpret the real world. Extra serotonin allows more stimuli to be treated than usual. Normally, the brain filters irrelevant stimuli, but with LSD this is not the case. This overstimulation causes changes in thought, attention, perceptions, and emotions. These alterations appear as hallucinations. The sensations seem real, but they are created by the mind. Perceptions can involve one or more of the five senses. This can also cause a mixture of senses called synesthesia. People report “hearing” colors and “sighted” sounds. LSD Uses LSD is currently listed in Schedule I of the Controlled Substances Act, the most penalized category of drugs. Schedule I drugs are considered “high potential for abuse” and no medical use currently accepted. The production and sale of this drug are illegal in many countries, but some people have requested its reclassification. According to them, this could be useful for research and development purposes of clinical applications. However, scientists considered psychedelics as promising treatments to help treat a wide range of psychiatric diagnoses, including alcoholism, schizophrenia, autism spectrum disorders and depression. Recent results of epidemiological studies have shown lower rates of mental and suicidal disorders among people who have used psychedelics such as LSD. It is used for the following purposes It is used as a Recreational drug It is used as a spiritual drug because it can catalyze intense spiritual experiences Currently, there is no medical use approved by the authorities. Hazards Following are some health hazards of using this drug. This may not be the full list you can consult your doctor after experiencing the following or other severe risks. LSD users often suffer from loss of appetite, insomnia, dry mouth and tremors. Visual changes are among the most common effects: the user can choose the intensity of certain colors. Body temperature can rise or fall as blood pressure and heart rate increase or decrease. Sweating or chills are not uncommon. He also feels extreme mood swings, ranging from “feeling of happiness” too intense terror. The worst is that the LSD user cannot identify the sensations produced by the drug and those that are part of reality. Not only do they separate themselves from the usual activities of life, but they also feel the need to take more and more drugs to try the same sensation again. Others experience terrible and terrible thoughts and feelings, they fear losing control of their lives, they fear madness and death and despair when they use LSD. Once started, a “bad trip” often cannot be stopped, which can take up to twelve hours. In fact, some people never recover from acid-induced psychosis. Some users of this drug experience intense happiness that they confuse with “lighting”. At a sufficiently large dose, LSD creates delusions and visual hallucinations. The time and the sense of the user’s self-defense. The dimensions and shapes of objects are distorted, as are movements, colors, and sounds. Even touch and normal bodily sensations become something strange and strange. The sensations seem to overlap, giving the user the feeling of feeling the colors and seeing the sounds. These changes can be scary and cause panic. Many users have flashbacks or repetitions of the LSD path, often without warning, long after taking LSD. The ability to make reasonable decisions and identify common risks is compromised. An LSD user can attempt to exit a window to “look” at the floor. You might find it fun to watch the sunset without rejoicing that you’re in the middle of a busy intersection. As LSD accumulates in the body, users develop tolerance to the drug. In other words, some repeat users have to take them at ever higher doses to reach a “high level”. This increases both the physical impact and the risk of miscarriage, which can lead to psychosis. Management errors and backtracking are just some of the risks of using LSD. Users of this drug may have a relatively long psychosis or severe depression. How do you take it? LSD is always taken orally and injected for

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Deriphyllin Tablet: Uses, Side Effects, Dose & FAQs

Deriphyllin tablet is a combination medicine used in the prevention of wheezing, shortness of breath, and chest tightness associated with lung diseases such as Asthma, chronic bronchitis, emphysema, chronic obstructive pulmonary disease (COPD) ). Deriphyllin is the brand name for the combination of two very similar generic drugs: Etophylline and Theophylline. Etofyline – also called etophylline, is a modified form of Theophylline. Theophylline is a methylxanthine drug used under various brands in the treatment of respiratory diseases such as chronic obstructive pulmonary disease (COPD) and asthma. It relaxes the muscles evenly, also known as bronchodilatation. This causes dilation of the bronchial muscles. It simply means that the space in the lungs expands so that more air can be received and it can easily enter and exit the lungs. In response to stimuli, it helps to increase the supply of air into the lungs. It is manufactured by Zydus Cadila and contains the drugs Etofillina and Theophylline. Deriphyllin Tablet Uses Deriphyllin tablet is used in the treatment and prevention of the following medical conditions Asthma Difficulty in breathing Chest tightness Shortness of breath Wheezing Breath shortness Breathlessness Interruption of breathing in newborns Chronic Asthma Side Effects Common side effects associated with the use of Deriphyllin are Nausea Vomiting Restlessness Headache Stomach upset Other side effects include Palpitation Seizure and Tremors Diuresis Precautions Avoid Derphyllin the following conditions or discuss with your health care providers in case of the following conditions Cardiac failure, Epilepsy, Hyperthyroidism, Hypertension, Renal or hepatic dysfunction, History of peptic ulcer disease, Diabetes mellitus, Glaucoma, Chronic alcoholism, Severe hypoxemia, Acute febrile illness, COPD, Pregnancy And Lactation. Interactions If you use other medicines or over-the-counter products at the same time, the effects of Deriphyllin may vary. This can increase the risk of side effects or prevent the medicine from working properly. Consult your doctor before taking Deriphyllin medicines with the following medicine as it may worsen the side effects. Carbamazepine, Fluvoxamine, Diuretic Drugs Phenytoin and Propranolol. Monoamine oxidase inhibitors Tramadol The doctor will help you get the right dosage and ask you to stop one of the medications or give you a substitute for Deriphyllin. Dosage The recommended dose for the drug is 400 or 600 mg once a day in the morning or evening. The usual Adult and Child oral dose for acute bronchospasm is 5 mg/kg every 6-8 hours. The usual adult oral dose for chronic bronchospasm is 300-1000 mg in divided doses every 6-8 hours daily. As modified-release preparations: 175-500 mg every 12 hours. The usual Initial dose in neonates 24 days for apnoea is 1 mg/kg every 12 hours; >24 days: 1.5 mg/kg every 12 hours. The usual Parenteral Adult dose for Severe bronchospasm is 4-5 mg/kg as the initial dose, through infusion, over 20-30 minutes, followed by maintenance: 0.4 mg/kg/hr. The usual Child dose for Severe bronchospasm is 4-5 mg/kg as an initial dose, through infusion, over 20-30 minutes, followed by a maintenance dose of 1-9 yr: 0.8 mg/kg/hour; less than nine years: 0.6-0.7 mg/kg/hour. Frequently Asked Questions   What is DeriphyllinTablet? Deriphyllin Tablet is the brand name of a combination of two active ingredients, namely, theophylline and etophylline. Both of these drugs work as bronchodilators. What is Deriphyllin used for? It is used for different conditions like Asthma, wheezing, shortness of breath, chest tightness, chronic bronchitis, emphysema, chronic obstructive pulmonary disorder, etc. What are the side effects of Deriphyllin? Common side effects of taking Deriphyllin are Nausea, Vomiting, Stomach Upset, Diuresis, palpitations, etc. Check above. Can Deriphyllin be taken after food or before food? Deriphyllin Tablet is to be taken on an empty stomach. Take this medicine 1 hour before or 2 hours after food. You can take it with food if stomach upset occurs. Is Deriphyllin safe in pregnancy? No, it is not safe for pregnant women to take the tablet since it belongs to the drug group known as selective serotonin reuptake inhibitors (SSRIs), which are used to treat obsessive disorder. Is Deriphyllin safe during breastfeeding? You should always consult before starting the medication and clear all the possible benefits and risks before the consumption of the medicine. Can Deriphyllin provide relief from Asthma? Yes, this medicine can provide relief from Asthma. However, one should consult a doctor before taking this drug. Is it safe to take with alcohol? Deriphyllin Tablets may cause excessive drowsiness with alcohol. Can I drive while taking the Deriphyllin Tablet? It is not known whether Deriphyllin Tablet alters the ability to drive. Do not drive if you experience any symptoms that affect your ability to concentrate and react. Is it a Habit-forming drug? Many medicines do not come with the potential to cause addiction or abuse. It is advised to consult the doctor and check the product package to make sure that medicines do not belong to such a category. What Happens if I miss a dose of Deriphyllin? You should immediately take the missed dose the moment you remember but should avoid it if it is the time of the next dosage. It is necessary that you skip the missed dose in such cases and not double up the dosage next time. What happens if I overdose on Deriphyllin? In cases of overdose, you must visit a doctor immediately, as the side effects can cause serious health problems. Therefore, it is important that you stick to the dosages as prescribed. What Happens if I take an expired dose of Deriphylline? Taking a single dose of the expired tablet might not cause any harm. It is advised to take the tablet as instructed. An expired drug may not be effective in treating your illness, but it may cause some adverse effects on your health, which can be harmful if it is not treated on time. Read Next: More Generic Medicine and Brand Medicine

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Omnacortil: Uses, Side Effects, Dosage, FAQs

Omnacortil is the brand name of Prednisolone, Which belongs to a group of drugs known as corticosteroids. Macleods Pharmaceuticals Pvt. Ltd manufactures it. Omnacortil is used to treat and prevent different conditions such as breathing disorders, lupus, and skin conditions like psoriasis. It is also used to treat symptoms such as swelling, redness, rashes on the skin, inflammation, etc. Omnacortil 10 Mg also aids in providing relief from some severe health issues such as asthma, leukemia, lymphoma, nephrotic syndrome and rheumatoid arthritis. Omnacortil Tablet is available in different strengths. Omnacortil 40 mg Omnacortil 20 mg Omnacortil 10 mg Omnacortil 5 mg Omnacortil 2.5 mg Omnacortil Uses It is used in the treatment and prevention of various medical conditions, such as; Allergic states Collagen disorders Skin conditions Rheumatic disorders Neoplastic disease Gastro-Intestinal disease Hematological disorders Nephrotic syndrome. Respiratory disease Omnacortil Side Effects Common side effects associated with the use of this drug include Nausea Headache Vomiting Reduction in bone density Weight gain Excitement Skin thinning Behavioral changes Mood changes Stomach upset Increased glucose level in the blood Serious side effects and their symptoms can include the following: Severe allergic reactions Changes in emotions or moods, such as depression Changes in vision Eye pain Infection. High blood sugar. Warnings Avoid Omnacortil tablets if You suffer from kidney disease, Cirrhosis, Diabetes, Kidney diseases, Thyroid, Depression or Hypertension, Pregnant and breastfeeding women  Genetic or acquired allergies Interaction with Drugs   Omnacortil Tablet may interact with the following drugs. Avoid Concurrent use of Prednisolone with the following medications as it may cause adverse reactions   Fluoroquinolone Ethinyl Estradiol Azole antifungal agents Nonsteroidal anti-inflammatory drugs Antihypertensives Phenytoin Retinoid (for skin conditions) Barbiturates, phenytoin, phenylbutazone, primidone. Thyroid drugs Methotrexate Antacids Anticoagulant medicines are used to thin blood Aminoglutethimide, carbenoxolone or salicylates, acetazolamide. Oral contraceptives Note: This is not a complete list of Interactions. This drug may interact with other products and cause side effects. Consult Your doctor. Dosage   The usual starting dose is 5 mg to 60 mg daily, depending on the disease being treated. The amounts are adjusted according to the patient’s response. In general, the lowest effective dose is used. Corticosteroids, which are administered in multiple doses during the day, are more effective, but also more toxic, than an alternative treatment twice the daily amount allocated every morning. It is advisable to take it at the dose and duration prescribed by the doctor. It is generally recommended to dissolve the drug in a glass of water before use to maximize its effectiveness. The usual recommended dose for the treatment of multiple sclerosis is 200 mg of Omnacortil for seven days. Your doctor will prescribe a dose based on your medical condition. The usual recommended dose for adrenogenital syndrome is 5 to 10 mg of omnacortil tablet daily in a single dose. Prednisolone should be taken with a meal to reduce irritation of the stomach and intestines. Frequently Asked Questions (FAQs) 1. What is Omnacortil Tablet? This product contains prednisolone, which belongs to the group of medicines called corticosteroids. It is essentially a relief of inflammation in the human body and is also used to treat skin conditions such as asthma and arthritis. 2. What is Omnacortil used for? This medicine is used for the treatment, prevention and control of conditions such as Allergies, Asthma, Lymphoma, Nephrotic syndrome, Idiopathic Sarcoidosis, Idiopathic Thrombocytopenic, Chronic lymphatic leukemia, Multiple sclerosis, Osteoarthritis Psoriasis, Hemolytic anemia. 3. What are the side effects of Omnacortil Pills? Common side effects: nausea, headache, vomiting, excitement, thinning of the skin, decreased bone density, weight gain, mood swings, upset stomach, behavioral changes, and elevated blood sugar levels. More information can be found above. 4. How to use Omnacortil Tablet? Take this medicine at the dose and time recommended by your doctor. Swallow it as a whole. Do not chew, crush or break. 5. How does the Omnacortil Tablet work? This drug contains mainly prednisolone active salt. This belongs to the family of medicines called glucocorticosteroids. Prednisolone can inhibit leukocyte infiltration at the inflammation site, disrupt inflammatory response mediators, and suppress humoral immune responses. 6. Is it safe to take omnacortil during pregnancy? The tablet is generally considered safe for use during pregnancy. Care should be taken before taking this medicine to avoid side effects. 7. Is it safe while breastfeeding? This drug is known to be excreted in small amounts through breast milk. Use this medicine only when needed if other safe alternatives are unavailable. 8. Is it safe with alcohol? Patients are advised not to consume alcohol, as in some cases, this can cause excessive sleepiness or decrease the effectiveness of the medicine. Therefore, it is recommended to abstain from alcohol during the administration of this tablet. 9. Can I drive after consuming Omnacortil? In some cases, this tablet may cause drowsiness and dizziness. Therefore, patients are advised to avoid driving after consuming these tablets. 10. Is omnacortill a habit that forms the drug? Patients taking this medication reported a pattern of habit formation. It is advisable to read the label carefully before administering any medication. 11. What happens if I miss a dose of Omnacortil? It is advisable not to lose the dosage; even if you miss it, consume it as soon as you remember. Do not consume the missed dose if it is time for the next dose. 12. What happens if I overdose on Omnacortil Tablet? In case of overdose, you may experience symptoms such as headache, skin peeling, acne, increased heart rate, increased appetite, increased sweating, menstrual problems or a few other symptoms. In these cases, treatment should be stopped, and the doctor should be consulted immediately. 13. How to store Omnacortil? Omnacortil is recommended to keep the medication in a cool, dry place, away from moisture, direct heat, and sunlight. It is not recommended to freeze or refrigerate the tablet. It is advisable to protect it from children and pets.

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Breast cancer: Causes, Symptoms, Treatment

Breast cancer is a disease in which the breast cells grow out of control. There are different types of breast cancer. The type of breast cancer depends on the mammary cells that turn into cancer. After skin cancer, breast cancer is the most commonly diagnosed cancer among women in the United States. Breast cancer can occur in men and women, but is much more common in women. Breast Cancer Symptoms The signs and symptoms of breast cancer can be: A knot in the chest or a thickening that feels different than the surrounding tissue. Changes in the skin on the chest, such as. B. dimples Change the size, shape or appearance of a breast. The pigmented skin surrounding the nipple (areola) or breast skin Redness or tingling of the breasts, like the skin of an orange Causes The exact cause of breast cancer is not fully understood but we know that the risk of breast cancer increases with age. After puberty, a woman’s breast consists of fat, connective tissue and thousands of lobes, tiny glands that produce milk for lactation. Tiny tubes or tubes transport milk to the nipple. In cancer, the body cells multiply uncontrollably. It is an excessive cell growth that causes cancer. Breast cancer usually begins in the lining of the milk ducts or in the lobes that supply them with milk. From there it can spread to other parts of the body. Treatment Some treatments eliminate or destroy the disease in the breast and near tissues, such as lymph nodes. This includes: Surgery to remove the entire breast, called mastectomy, or just to remove the tumor and surrounding tissue, lumpectomy or surgery to maintain the breast. There are several types of mastectomies and lumpectomies. Radiotherapy that uses high energy waves to kill cancer cells. Hormone therapy uses drugs to prevent hormones, especially estrogen, from stimulating the growth of breast cancer cells. Drugs include tamoxifen, in pre- and post-menopausal women and aromatase inhibitors, including anastrozole (Arimidex), exemestane (Aromasin) and letrozole (Femara) in postmenopausal women. Side effects can include hot flashes and vaginal dryness. Some types of therapy work by preventing the ovaries from producing hormones, either through surgery or medication. Fulvestrant (Faslodex) is an injection that prevents the binding of estrogen to cancer cells. Chemotherapy uses drugs to kill cancer cells. Because these powerful medicines fight the disease, they can also cause side effects such as nausea, hair loss, early menopause, hot flashes and tiredness. Targeted therapies such as lapatinib (Tykerb), pertuzumab (Perjeta) and trastuzumab (Herceptin). These drugs stimulate the body’s immune system to destroy cancer. They target breast cancer cells that contain a high proportion of HER2. Palbociclib (Ibrance) and ribociclib (Kisqali) block a substance that promotes cancer growth. Palbociclib and ribociclib are indicated with an aromatase inhibitors for postmenopausal women with certain advanced cancers. Abemaciclib and palbociclib are sometimes used in combination with a hormonal treatment with fulvestrant (Faslodex).

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This Male Birth Control Pill Passes Human safety Test

A Male Birth Control pill for men has passed the first tests of human safety, experts at a leading medical conference have heard. The Male Birth Control Pill once a day contains hormones designed to stop sperm production. It would be a welcome addition to condoms or vasectomy, the only options currently available to men. But the doctors attending the annual meeting of the Society of Endocrinology were informed that it would take another decade to bring them to the market. Study The results of the Phase 1 study were presented on March 24 at the annual meeting of the Endocrine Society in New Orleans. Stephanie Page, a professor of medicine at the University of Washington School of Medicine, co-directed the study with Christina Wang, professor of medicine at UCLA in Los Angeles. The results of the study indicate that the male experimental oral contraceptive reduces sperm production while preserving libido. The pill is called dodecylcarbonate of 11-beta-methyl-19-nortestosterone or 11-beta-MNTDC. It is a modified testosterone that combines the action of a male hormone (androgen) and a progesterone. The study involved 40 healthy men at two sites: the UW Medical Center in Seattle and the Biomedical Research Institute in Los Angeles, Torrance, California. Ten study participants randomly received one placebo capsule and another 30 received 11-beta-MNTDC in one of two doses. ; 14 men received 200 mg and 16 received the 400 mg dose. The subjects took the drug or placebo once a day for 28 days. The researchers reported that the levels of two hormones needed for sperm production had significantly decreased in the cohort studied compared with those who took the placebo. And among those who took the androgen-based drug, hormone levels needed for sperm production dropped significantly compared to placebo, returning to normal after the trial. In fertile men, new sperm are constantly produced in the testes, activated by hormones. The problem is the temporary blockage of this effect without decreasing hormone levels to the point of creating side effects. But the latest male pill, which is currently being tested by researchers at LA BioMed and the University of Washington, should achieve this goal, say the researchers. Side effects In contrast, the adverse effects of these male birth control pill were few and light. Erectile dysfunction Five men who took the pill reported a slight decrease in sexual desire. Two of them described mild erectile dysfunction, but the sexual activity did not decrease, no participant stopped taking it due to side effects and all passed the safety tests. The researcher behind the work, Professor Christina Wang and her colleagues, are enthusiastic but cautious about libido as a side effect. Other scientists have tried to administer long-acting contraceptive hormones in a vaccine administered every two months. But they stopped recruiting men for their Phase 2 study, examining the safety and effectiveness of the injection, after some volunteers reported side effects, including mood disorders or depression. For men who do not feel like taking hormones, the researchers looked for ways to block the flow of semen, preventing it from leaving the penis, effectively, a non-surgical vasectomy. Vasalgel, a polymeric material that is injected into the two channels that carry sperm from the left and right testes to the penis, is being developed as a reversible, long-lasting, non-hormonal male contraceptive. So far, it has only been tested on animals, but the researchers behind this project have recently received funds to start human trials.

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Freestyle Libre: A Helpful Guide for Diabetic Patients

Freestyle Libre is a device manufactured by Abbott Lab that is used to monitor the daily level of glucose in your body without damaging your fingers. Freestyle Libre is a kind of glucose monitoring system. A blood glucose monitoring system measures blood sugar levels continuously throughout the day. A freestyle libre system is made up of: A reader – a small device you use to scan the sensor to see your sugar levels A sensor you stick to your arm A new mobile app which work as a reader. The best thing about Freestyle Libre Sensor is that it keeps track of your blood sugar level so you can identify trends and that can help you make better decisions about your health, such as How to adapt your diet or quantity of insulin to take. This device is a very practical, easy to use and accurate monitoring system for those who are fed up with the traditional finger system. Benefits of Freestyle Libre Following are some of the benefits of this device It’s Accurate Convenient User friendly Difference Between a Freestyle Libre and a conventional Finger prick Glucose monitoring This device measure your glucose in the interstitial fluid of the subcutaneous tissue while in conventional monitoring you measure glucose in the blood. This device collect data with the help of a scanner while the blood glucose monitoring a finger prick is needed after each reading. This device provide you a continuous measuring of glucose level while in conventional each reading represent one moment in time. The conventional glucose monitoring is time consuming while this new system take data from 1 sec scan. How it Work? FreeStyle Libre is a small, waterproof and fully disposable sensor that can be carried on your arm for 10 days. When scanning with the sensor, the meter displays a real-time blood glucose reading and a trend arrow, which is approved for dosing insulin without a finger. Unlike other CGM devices, Libre does not require digital perforation calibration. Free Freestyle measures blood glucose using a small sensor located on the back of the arm. The sensor, which is the size of two superimposed parts, allows the blood glucose measurement in real time for 10 days, day and night. The sensor can also read blood sugar through clothing, making testing discreet and comfortable. How do I use freestyle? Step 1 When you open your new FreeStyle Libre Reader Kit, you’ll find the Quick Start Guide, the Reader, the User Guide, a USB cable, and the AC adapter. The Kit consists of two parts: The sensor applicator and The sensor package. Step 2 Simply place the sensor on the arm for convenient glucose measurement without lancets or test strips. Further information can be found in the operating instructions. Contraindications This is contraindicated in certain Procedure such as X-ray MRI CT scan Diathermy treatment. It’s better you remove the device before doing the above procedures. Frequently Asked Questions   1. What’s a FreeStyle Libre? It is a device manufactured by abbott Lab and is used to monitor daily glucose level in your body without finger pricks. It is different from the old monitoring system because it doesn’t require any finger pricks and it also provide continuous monitoring for 10-14 days. 2. How much is the FreeStyle Libre? The cost is different in different pharmacies.  However the cost for 10 day Freestyle libre sensor start from 35$ to 52$. While the cost for a Freestyle libre Reader (One time purchase)  start from 70$ to 97$. 3. Can you shower with FreeStyle Libre? The sensor is water-resistant and can be worn while bathing and showering. 4. Is there a needle in the FreeStyle Libre? Yes, One side of the sensor contains a tiny needle that goes inside of your skin. 5. How many FreeStyle Libre sensors are in a box? The starter pack comes with one FreeStyle Libre reader and two FreeStyle Libre sensors, each lasting for up to 14 days in Canada, Australia and 10 days in United States. 6. What is a Freestyle libre sensor? The sensor is device that is applied on to the back of the upper arm with a simple, disposable device called an applicator. 7. Do you need a prescription for FreeStyle Libre? Yes,  this product need a doctor prescription in the US. 8. Can you swim with FreeStyle Libre? This sensor is water-resistant and can be worn swimming as long as you Do not take it deeper than 3 feet (1 meter) 9. Is there any app for Freestyle Libre? The FDA approved a mobile application for use with Free Freestyle 10 and 14 day blood glucose monitoring systems, which allows diabetic patients to monitor blood glucose levels on compatible iPhone devices. 10. How long will the freestyle sensors last? In some countries, such as the United Kingdom, Australia and Canada, you can use Free Freestyle for up to 14 days. In the United States, however, it is only allowed for 10 days. Check out this article about 10 Signs that you are diabetic .

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