5 Best Over The Counter ED Pills Recommended By Pharmacist

Have you ever heard of over the counter ED pills? Let’s find out what the research says about it? 

Erectile dysfunction (ED) is a condition in which a person cannot get and keep an erection firm enough to have sexual intercourse.  This condition is also called impotence.

This is a widespread disorder affecting approximately 30 million men in the US alone.

There are many different causes of ED, but the most common cause is stress and anxiety. Other causes include cardiovascular disorders, sleep disorders, diabetes, hypertension, drug use, alcohol consumption, and obviously the natural aging process.

Treatment options include the use of prescription drugs like sildenafil, vardenafil, avanafil, and tadalafil. These drugs increase blood flow to your penis to help you treat ED.

Drugs like Viagra (sildenafil) and Cialis need a doctor’s prescription, plus they are expensive and may cause some undesirable effects. Based on these complaints, many people with ED seek out other options, which sometimes include over the counter ED pills.

Some of the natural ingredients like L-arginine, dehydroepiandrosterone (DHEA), ginseng, Yohimbe, and propionyl-L-carnitine are all available in OTC pills.

The question is still there, what over-the-counter ED pills are out there, and do they actually work?

Let’s find out the research behind each ingredient.

⊕ L-arginine:

It is an amino acid that may improve your ED by increasing blood supply to your penile tissues. It is the most commonly found ingredient in many OTC pills. It is an effective treatment option for ED if used with L-arginine. [1]


Another most important ingredient commonly used in over the counter ED pills and supplements is Dehydroepiandrosterone (DHEA). It is a steroid hormone and can be found in soy products and yams. According to a study, this hormone deficiency is associated with a higher risk of erectile dysfunction. [2]

⊕ Yohimbe:

This is another ingredient most commonly used in many sexual dysfunction pills like Zyrexin and many other such supplements. It promotes a neurotransmitter (Norephineprine), which is vital for achieving an erection. It is an approved treatment for erectile dysfunction. [3]

⊕ Propionyl-L-carnitine:

Another one is Propionyl-L-carnitine, and its mechanism is the same as other over the counter ED pills as it also increases the blood flow to the penile tissues and is an ideal remedy for ED. [4]

But natural supplement doesn’t mean totally safe.

Please keep in mind that these are natural ingredients, but that doesn’t mean they are fully safe to use. They might cause some side effects.

For example

  • Yohimbe may be linked to high blood pressure and increased heart rate.
  • L-arginine might cause diarrhea, abdominal pain, gout,  bloating, nausea, and vomiting.
  • Propionyl-L-carnitine is generally considered safe if taken orally, but sometimes it may cause nausea, vomiting, stomach pain, fishy odor, weakness, and chest pain (angina).
  • DHEA may also cause minor side effects like oily and greasy skin, acne, and increased hair growth in the armpits and pubic area.

Let’s talk about some of the most commonly used and best over the counter ED pills that work fast and easily available on the market.

It’s important to note that this list is based on our honest opinion and several hours of research on different brands.

Let’s have a deep look.

5 Best Over The Counter ED Pills

1. VigRx Plus

Our Top Pick (VigRx Plus)

They Offers 67 Days Risk Free Money Back Guarantee

Contains Research Based Ingredients

No harmful ingredients

Effects are long lasting

1.2 million boxes of VigRx already sold

This is one of the best over the counter sex pills and an absolute leader in the male enhancement space. It contains some natural ingredients that are important for men’s virility. It can be found exclusively on VigRx official site.

VigRx contains many research-based ingredients that are already proven to effective in ED and other sexual health issues. Some of the ingredients include ginkgo Biloba leaf, Asian red ginseng, and Catuaba bark to enhance stamina and male performance. These ingredients make it the best medicine for erectile dysfunction without side effects or have shallow unwanted effects.

To get more out of this supplement, you should use it daily for 30 to 60 days continuously, and according to the product manufacturer, it is 70% effective.

Why I placed it on top of over the counter ED pills?

  • This brand offers a 67 days risk-free money-back guarantee.
  • It has been formulated after decade-long research on the ingredients and their combination.
  • The second thing it is formulated without using any cheap and harmful additives like binder and fillers.
  • The effect of this supplement is long-lasting, and it is safe to use.

Read Our Full and Honest VigRx Plus Review—one of the best natural pills to last longer in bed.

2. Zyrexin—One of the best over the counter ED Pills


Product Full Name: Zyrexin World's Strongest Sexual Enhancer

Manufacturer: Superbalife International LLC.

Best actual price: 59.95$ per 60 tablets.

Where to Buy Zyrexin?: Company website.

Our Ratings

Zyrexin is one of the best over the counter sex pills containing Yohimbe Extract, Butea Superba extract, Epimedium extract, Ginkgo Biloba Xanthoparmelia Scabrosa Extract, Cnidium Extract, L-arginine, and Velvet Bean Extract.

The manufacturer claims that this is a quick action supplement, and the effects will last for at least 24 hours. They also claim that it is safe to use with no side effects, but as we all know that this supplement contains Yohimbe, which can cause some side effects.

The price of these over the counter erectile dysfunction pills is 30-35$ per 30 capsules bottle, which means it is not a cheap product but does it actually work? As a pharmacist, this is not a bad product as it contains some ingredients that will work for some people. The customer reviews were mixed, and most of the users were not happy with the supplement.

Please read our Zyrexin Review—one of the best non prescription ed pills.

3. Libido Max

Libido Max

Product Full Name: Libido Max Power Exteding Formula

Manufactured By: Applied Nutrition

Where To Buy? Official Site and Amazon

Amazon Rating

It is another popular male enhancement product that contains some natural organic ingredients like  L-arginine, horny goat weed, and Yohimbe extract.

Libido Max also uses the same mechanism by which other sexual products increase the blood circulation to the penis and improve the erection. It increases the production of nitric oxide in the body, which improves circulation in the body.

This product is not safe for people with underlining medical conditions, especially heart diseases and blood pressure. The Yohimbe extract in this supplement may cause some unwanted side effects like stomach ulcers and other gastrointestinal issues.

The customer reviews on Libido Max were mixed, and most of the users were not happy with the results. For example, if you look at the verified Amazon reviews, you will see that for many, Libido Max is one of the best over the counter sex pills, and there are also many unsatisfied testimonials on Amazon.

Read Next ⇓

4. Male Extra

Male Extra

Product Name: Male eXtra Bigger Harder Longer

Manufactured By: Male eXtra

Best Place To Buy Male Extra: Amazon and Official Site

Customer Ratings

Total Ratings: 13

Like all other male enhancement pills, this one also claims to be one of the best over the counter erectile dysfunction pills. It also promises men to experience better performance in the bedroom.

The most prominent feature of this formula is that it comes with a satisfaction guarantee. Another best thing is that there is no auto-shipping program for this brand. They also offer you discreet shipping, which is very much important for those wanting privacy.

It is different from the above supplement in their ingredients like they use MSM (Methyl Sulfonyl Methane), Ellagic acid obtain from pomegranate, L-arginine, L-methionine, and Cordyceps. These ingredients together work for the betterment of your sexual health and improve your erection.

It can cause hypotension, so if you already have low blood pressure, you should be careful with that. If you are already taking other medications like prescription drugs, you should consult with your doctor.

The customer reviews on Amazon and other online stores are not satisfactory, and most people rate it a 1-star rating, which may be a concern for many people.

Male Extra’s usual recommended dose is 3 capsules each day in the morning with a glass of water.

5. Virectin


Product Full Name: Virectin Loaded

Manufacturer : Virectin Gentopia

Best Place To Buy Virectin: Amazon and Official site

Customer Reviews

Total Ratings: 39

This is the last on the list of best over the counter male enhancement pills. Like other brands in this list, Virectin is also a natural sex booster. It is manufactured by Gentopia Laboratories- a company that is known for producing high-quality products.

As per the claims, It contains some natural and over the counter viagra alternatives that may support a stronger sex drive and improve low libido, help the male perform better in the bedroom, support stronger, more powerful orgasms, and allow you to give your partner greater sexual pleasure.

Some of the ingredients present in this formulation are somehow different from that of the above 4. It also contains niacin, which may help you relax and widen your blood vessels and promote a long-lasting erection. It also has other ingredients included in its formulation.

The usual recommended dose is 3 capsules per day taken simultaneously, but you can adjust your dose as per your needs. Please don’t exceed the recommended dose as it may cause unwanted effects.

If you look at the customer reviews on Amazon, you will find out that the reviews are not very satisfactory, and most of the users have rated it a 1-star review.

Best Foods and Nutrients For Erectile Dysfunction

One way to improve your sexual health is by supporting your body with nutrients and foods your penis needs.

The number one reason we all need to pay attention to is using nutrition to keep our bodies healthy. The typical diet includes too few of the specific nutrients the penis needs. Apples and carrots are the best foods for prostate and penis health—but as we know, many of us don’t include them in our day-to-day life.

Even if you emphasize sex-focused nutrition in your daily routine, it’s really tough to get the recommended amount that your body needs to perform at its highest levels or preclude age-related erectile dysfunction and Low Testosterone.

Here is a list of the best foods that can boost your testosterone and improve your ED symptoms.

  • Avocados: are an excellent source of important nutrients like zinc, vitamins like Vitamin E, healthy fats, and potassium. These are proven to be effective for ED and fertility. [5] [6]
  • Carrots: This vegetable keeps your sperm healthy and is proven to improve both sperm count and fertility. Carotenoid is a chemical found in carrots that may improve sperm quality and motility. [7]
  • Spinach: contains folate and magnesium, which plays a vital role in male sex functions and improving testosterone. Studies suggest that the deficiency of Folic acid may lead to erectile dysfunction. So eat more Spinach and enjoy your healthy sexual life. [8]
  • Caffeine: also improves blood flow and is effective in preventing erectile dysfunction. Some studies also suggest that drinking 2-3 cups of coffee a day prevent ED. [9]

Which erectile dysfunction drug is best?

Or you say what is the most effective pill for ed?

The simple answer is Viagra—if you are looking for a prescription. Viagra is the drug of choice for erectile dysfunction.

While VigRx Plus is the best OTC erectile dysfunction supplement, other prescription drugs like Cialis, Vardenafil, Avanafil are also used very commonly, but these drugs need doctor Rx.

The above-discussed supplements are safe, but most market products have some hidden ingredients that might not be safe.

Here is a list of products that the FDA has cautioned people to avoid.

FDA Warning about Unsafe Supplements

In 2009 the FDA cautioned about the “hidden dangers” of products generally referred to as ED supplements but was not safe to use. These products contain traces of prescription drugs like sildenafil and other drugs. According to the FDA, you should avoid these products.

Verdict—Best Over The Counter ED Pills

As a pharmacist, I would recommend natural and home remedies to treat erectile dysfunction. Natural ways to overcome ED include– doing regular exercise, staying active, quitting smoking, drinking less alcohol, and finding ways to destress yourself. The real and simple trick to cure ED is doing regular exercise for more than 30 minutes.

  • According to a study, simply walking for 30 minutes a day can reduce ED risk by 41%.
  • Another simple trick to cure ED is to stop smoking. This study shows that quitting smoking may improve your erection.
  • Sexual dysfunction is prevalent among heavy drinkers- study.

If you have already decided to buy a supplement, the above list of products is highly recommended.

Please note that no supplement can be as effective as prescription drugs like sildenafil because they are effective and FDA-approved. However, certain natural ingredients may also help you increase your virility and improve your sex performance.

⇒ Why people often opt for an over the counter ED Pill?

There are a few reasons.

  • They are over the counter means you don’t need any doctor’s prescription for these products.
  • They use natural ingredients; that’s why they are relatively safe to use with low to no side effects.
  • They are easily available in online and offline pharmacies.

⇒ Is there any over-the-counter viagra substitute?

No, viagra is a prescription drug approved by the FDA to treat erectile dysfunction. There are no OTC viagra alternatives, but some natural herbs and other ingredients that, according to some studies, can be effective for ED.

However, as I mentioned above, some natural ingredients can improve your sex drive and work, like over the counter Viagra.

⇒ So what is the best erectile dysfunction pill over the counter?

All of the above products are best in terms of safety and efficacy, but we recommend an over the counter erectile dysfunction pill like VigRx Plus.

You can buy this supplement if you agree, and if you do not agree with our recommendation, you can go for other alternatives.