5 Best Over The Counter ED Pills [Pharmacist Recommendations]

Have you ever heard of over the counter ED pills? Let’s find out what the research says about it?

Erectile dysfunction (ED) is a condition in which a person cannot get and keep an erection firm enough to have sexual intercourse.  This condition is also called impotence.

This is a widespread disorder affecting approximately 30 million men in the US alone.

There are many different causes of ED, but the most common cause is stress and anxiety. Other causes include cardiovascular disorders, sleep disorders, diabetes, hypertension, drug use, alcohol consumption, and obviously natural aging.

Treatment options include the use of prescription drugs like sildenafil, vardenafil, avanafil, and tadalafil. These drugs increase blood flow to your penis to help you treat ED.

Drugs like Viagra and Cialis need a doctor’s prescription, and they can also be expensive. So based on these complaints, many people with ED seek out other options, which sometimes include over the counter ED pills.

Some of the natural ingredients like L-arginine, dehydroepiandrosterone (DHEA), ginseng, Yohimbe, and propionyl-L-carnitine are all available as an over the counter ED pills.

The question is still there, what over the counter ED pills are out there, and do they actually work?

L-arginine is an amino acid that may help you improve your ED by increasing blood supply to your penile tissues. It is the most commonly found ingredient in many pills, like Viagra over the counter. It is an effective treatment option for ED if used with L-arginine. [1]

Another most important ingredient commonly used in over the counter ED pills and supplements is Dehydroepiandrosterone (DHEA). It is a steroid hormone and can be found in soy products and yams. According to this study, this hormone deficiency is associated with a higher risk of erectile dysfunction. [2]

Yohimbe is another ingredient that is most commonly used in many sexual dysfunction pills like Zyrexin etc. It promotes a neurotransmitter (Norephineprine), which is vital for achieving an erection. It is an approved treatment for erectile dysfunction. [3]

Another one is Propionyl-L-carnitine, and its mechanism is the same as other over the counter ED pills as it also increases the blood flow to the penile tissues and is an ideal remedy for ED. [4]

Please keep in mind that these are natural ingredients, but they are not fully safe to use. They might cause some side effects. For example, Yohimbe may be linked to high blood pressure and increased heart rate.

Let’s talk about some of the most commonly used and best over the counter ED pills available on the market.

Please keep in mind that this list of “best over the counter ED pills” is based on our honest opinion and hours of research on different brands. Let’s take a look.

1. VigRx Plus

This is one of the best and absolute leader in the male enhancement space. It contains some natural ingredients that are important for men’s virility. It can be found exclusively on VigRx.com official site.

VigRx contains many research-based ingredients that are already proven to effective in ED and other sexual health issues. Some of the ingredients include ginkgo Biloba leaf, Asian red ginseng, and Catuaba bark to enhance stamina and male performance.

To get more out of this supplement, you should use it daily for 30 to 60 days continuously, and according to the product manufacturer, it is 70% effective.

Why I placed it on top of over the counter ED pills?

  • This brand offers a 67 days risk-free money-back guarantee.
  • It has been formulated after decade-long research on the ingredients and their combination.
  • The second thing it is formulated without using any cheap and harmful additives like binder and fillers.
  • The effect of this supplement is long-lasting, and it is safe to use.

Read Our Full and Honest VigRx Plus Review

2. Zyrexin

Zyrexin is another male enhancement supplement that contains Yohimbe Extract, Butea Superba extract, Epimedium extract, Ginkgo Biloba Extract, Xanthoparmelia Scabrosa Extract, Cnidium Extract, L-arginine, and Velvet Bean Extract.

The manufacturer claims that this is a quick action supplement, and the effects will last for at least 24 hours. They also claim that it is safe to use with no side effects, but as we all know that this supplement contains Yohimbe, which can cause some side effects.

The price of these over-the-counter ED pills is 30-35$ per 30 capsules bottle, which means it is not a cheap product, but the question does it actually work? As a pharmacist, this is not a bad product as it contains some ingredients that will work for some people. The customer reviews were mixed, and most of the users were not happy with the supplement.

Read our full and honest Zyrexin Review.

3. Libido Max

It is another popular male enhancement product that contains some natural organic ingredients like  L-arginine, horny goat weed, and Yohimbe extract.

Libido Max also uses the same mechanism by which other sexual products increase the blood circulation to the penis and improve the erection. It increases the production of nitric oxide in the body, which improves circulation in the body.

This product is not safe for people with underlining medical conditions, especially heart diseases and blood pressure. Also, the Yohimbe extract in this supplement may cause some unwanted side effects like stomach ulcers and other gastrointestinal issues.

The customer reviews on Libido Max were mixed, and most of the users were not happy with the results. For example, if you look at the verified Amazon reviews, you will see many unsatisfied testimonials on Amazon.

4. Male Extra

Like all other male enhancement pills, this one also claims to be one of the best over the counter ED pills. It also promises men to experience better performance in the bedroom.

The most prominent feature of this formula is that it comes with a satisfaction guarantee. Another best thing is that there is no auto-shipping program for this brand. They also offer you discreet shipping, which is very much important for those wanting privacy.

It is different from the above supplement in their ingredients like they use MSM (Methyl Sulfonyl Methane), Ellagic acid obtain from pomegranate, L-arginine, L-methionine, and Cordyceps. These ingredients together work for the betterment of your sexual health and improve your erection.

It can cause you hypotension, so if you already have low blood pressure, you should be careful with that. If you are already taking other medications like prescription drugs, you should consult with your doctor.

The customer reviews on Amazon and other online stores are not satisfactory, and most people rate it a 1-star rating, which may be a concern for many people.

Male Extra’s usual recommended dose is 3 capsules each day in the morning with a glass of water.

5. Virectin

This is the last in the list of best over the counter ED pills. Like other brands in this list, Virectin is also a natural sex booster. It is manufactured by Gentopia Laboratories- a company that is known for producing high-quality products.

As per the claims, It contains some natural and over the counter viagra alternatives that may support a stronger sex drive and improve low libido, help the male perform better in the bedroom, support stronger, more powerful orgasms, and allow you to give your partner greater sexual pleasure.

Some of the ingredients present in this formulation are somehow different from that of the above 4. It also contains niacin, which may help you relax and widen your blood vessels and promote a long-lasting erection. It also has other ingredients included in their formulation.

The usual recommended dose is 3 capsules per day taken simultaneously, but you can adjust your dose as per your needs. Please don’t exceed the recommended dose as it may cause unwanted effects.

If you look at the customer reviews on Amazon, you will find out that the reviews are not very satisfactory, and most of the users have rated it a 1-star review.

The above-discussed supplements are safe, but most of the market products have some hidden ingredients that might not be safe. Here is a list of products that the FDA has cautioned people to avoid.

FDA Warning about Unsafe Supplements

In 2009 the FDA cautioned about the “hidden dangers” of products generally referred to as ED supplements but was not safe to use. These products contain traces of prescription drugs like sildenafil and other drugs. According to the FDA, you should avoid these products.


As a pharmacist, I think no supplement can be as effective as prescription drugs like sildenafil because they are effective and FDA approved. However, certain natural ingredients may also help you increase your virility and improve your sex performance.

Is there any over the counter viagra substitute?

No, viagra is a prescription drug approved by the FDA to treat erectile dysfunction. There are no viagra alternatives, but some natural herbs and other ingredients that, according to some studies, can be effective for ED.

Why people often opt for an over the counter ED Pill?

There are a few reasons.

  • They are over the counter means you don’t need any doctor’s prescription for these products.
  • They use natural ingredients; that’s why they are relatively safe to use with low to no side effects.
  • They are easily available in online and offline pharmacies.

So what is the best erectile dysfunction pill over the counter?

All of the above products are best in terms of safety and efficacy, but we recommend you do your own research before buying any product.

If you really want to buy an over the counter erectile dysfunction pill, I recommend you should go for VigRx Plus.

You can buy this supplement if you agree and if you do not agree with our recommendation you can go for other alternatives.

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