Manzoor (Pharm-D)

Most adults have lower back pain at some point in their lives. The type and location of the discomfort can give clues about its cause. Still, it’s often difficult for people to figure out what is wrong without professional help because there are so many possible causes. Your lower back is a busy place. It consists of five vertebrae, cushioned by discs between them and held in place with ligaments that attach to the spinal column on one side or another so it can’t shift around too much. Thirty-one different nerves running through this area also help keep you safe from pain caused by kidney stones (which may need immediate medical attention). But, more importantly, allow us some flexibility when moving our bodies every day. Lower back pain right side above the buttocks can be caused by many different things. This article explores some possible causes and covers when you should see a doctor get appropriately diagnosed. Lower Back Pain Right Side Above The Buttocks—Causes When you feel pain in your back, it’s always best to see a doctor. Your symptoms might be due specifically or not just localized around one area of the spine and could indicate an issue with any number of other structures throughout our bodies. Here are some common causes; Strain & Sprain When you lift something heavy or twist, it is common for your back muscles to get stretched. This can cause swelling and difficulty moving in the affected area of muscle tissue because there’s been some tearing/stretching involved with this type of injury – thus creating an old term known as “back spasms.” There are many ways to avoid strain; When lifting heavy objects and improper technique can lead you into trouble fast. Don’t twist, jerk, or awkward bend the body position as this will increase your risk for muscle strain. Before each workout session begins, make light weightlifting movements such as squatting low bar squatting with an empty barbell on the floor. The best way to treat a mild sprain or strain is with rest, ice packs, and OTC pain relievers. This problem can also be treated with gentle massage, physical therapy, stretching exercise, electrical muscle stimulation, and surgery. For more severe injuries, it may be necessary for you to visit your doctor, who will prescribe muscle relaxants if needed. Appendix The second cause of lower back pain right side above the buttocks can be Appendicitis. Appendicitis occurs when the inflammation damages these tight membranes so they cannot filter out anything anymore – leading ultimately up to something blocking or infection within your Appendix itself. Appendicitis is a medical condition that requires immediate treatment in the form of removal. People who think they may have the disease should go to an emergency room and get treated with surgical removal of their Appendix, which we call “appendectomies.” Kidney Infection & Stones The kidneys are critical for eliminating waste and regulating acid-base balance. When infection damages them, it can lead to severe complications such as chronic kidney disease or sepsis that could eventually cost you your life. So the kidney infection can also cause back pain in the lower back. Kidney stones can be painful and lead to kidney damage if they aren’t treated quickly. In addition, a serious blockage could cause you to be dependent on a wheelchair, even though the pain is usually only located on one side of your back. The doctor may prescribe pain relievers to help ease a person’s symptoms, but drinking plenty of water is essential for preventing dehydration. Sometimes, treatment includes antibiotics that work by killing off the bacteria in your body that has infected kidney cells with its toxins over time (or at worst). Your doctor can perform various procedures for removing kidney stones, such as cystoscopy, shock wave lithotripsy, and percutaneous nephrolithotomy. Sciatica Sciatica is an uncomfortable pain caused by compression of the spine’s nerve root. The most common cause of this condition is herniated discs, bone spurs, or stenosis in some cases, which can compress part(s) concerning sending signals up to your leg towards the feet– commonly known as “sciatica.” So if you have sciatica, you may feel a throbbing pain in the lower back of your left or right side. Ulcerative Colitis Ulcerative colitis is a chronic condition that causes the lining of your large intestine to become inflamed. This usually leads to ongoing diarrhea, which may contain blood or pus, sometimes both! It can also cause abdominal discomfort and cramping that radiate down one side at a time for people who have this disease, too – though typically only on one left side when you’re sitting up straight (like if someone has their bed facing backward). There is no cure for ulcerative colitis. The goal of treatment is to achieve remission, which means that a person has few or no symptoms during this period and can live their life normally as though they weren’t suffering from severe illnesses like inflammatory bowel disease (IBD). There are many different medications available to alleviate the pain associated with Ulcerative colitis; however, some people may require surgical removal if more extreme measures aren’t effective enough – but nothing should be overlooked. Osteoarthritis Another reason for the lower back pain right side above the buttock can be Osteoarthritis — a condition that causes the cartilage between your vertebrae to break down. It can occur at any spot in the back, but lower-back pain and stiffness are common sites of Osteoarthritis; however, previous injuries may make this problem worse for some people. The use of medications like Acetaminophen (Tylenol,) Ibuprofen, etc., have been shown to help some people with mild-to-moderate pain from this kind of arthritis. Still, there are many other treatments available as well! Supplements like Relief Factor, Osteo bi flex and Arthrozene also promise to reduce inflammation and pain associated with arthritis. Exercise is one meaningful way to combat your discomfort by strengthening muscles around the joints, which helps support them and provide cushioning during movement. Lower Back Pain Right/Left Side Above Buttocks In

Introduction In the world of natural remedies, one compound has been making waves for its potential health benefits: Berberine. Derived from various plants like barberry, Oregon grape, and tree turmeric, berberine has a rich history in Ayurvedic and traditional Chinese medicine. In this comprehensive guide, we’ll delve into its diverse array of benefits, proper dosage, potential side effects, and more. Unveiling Berberine: What is it? Berberine, classified as an alkaloid, finds its roots in barks, leaves, twigs, rhizomes, roots, and stems of specific plants. Ayurvedic and traditional Chinese medicine have long hailed it for its antimicrobial, antiprotozoal, and antidiarrheal properties. Exploring Berberine’s Benefits 1. Blood Sugar Control and Beyond Clinical trials reveal that berberine could be a game-changer for those with type 2 diabetes. Its glucose-lowering effect competes with conventional anti-diabetic drugs. Additionally, berberine may enhance blood lipids liver function, and contribute to weight and fat loss. 2. Hormonal Health and Immune System Boost In conditions like polycystic ovarian syndrome (PCOS), berberine showcases promising results in improving hormonal health. For those with various metabolic disorders, it might reduce C-reactive protein (CRP), a marker of inflammation. 3. Berberine’s Role in Reproductive and Immune Health From PCOS to its potential anticancer effects, berberine emerges as a versatile ally in enhancing reproductive and immune health. 4. Lowering Blood Sugar and Cholesterol Berberine shines in reducing blood sugar levels, enhancing insulin effectiveness, and impacting various metabolic processes. Its potential to lower cholesterol, decrease triglycerides, and increase HDL cholesterol positions it as a multifaceted health ally. 5. Fighting Cancer Emerging studies suggest berberine’s inhibitory effects on various cancers, including colorectal, lung, ovarian, prostate, liver, and cervical cancers. 6. Gut Health Berberine’s antibacterial action contributes to gut health, promoting a balance of beneficial bacteria. 7. Weight Loss and Heart Health Berberine’s potential as a weight loss supplement and its positive impact on heart health further solidify its standing in the realm of natural remedies. Studies suggest that taking 500mg of this ingredient three times a day may help you reduce the weight.  Understanding Berberine’s Mechanism Berberine’s benefits stem from its influence on high-level controllers of energy homeostasis. Activating enzymes like AMP-activated protein kinase (AMPK), protein kinase c (PKC), and sirtuin 1 (SIRT 1), berberine regulates metabolism, immunity, and inflammation. Berberine’s Side Effects While berberine is generally safe, digestive side effects like upset stomach and constipation may occur. The supplement’s interaction with medications and its caution during pregnancy warrants careful consideration. What are the potential drug interactions of berberine? Berberine has the potential to interact with various medications due to its influence on drug metabolism enzymes. It is advisable to exercise caution and consult a healthcare professional before incorporating berberine into your regimen, especially if you are taking: Blood Sugar-Lowering Medications: Berberine’s ability to reduce blood sugar levels may enhance the effects of these medications, leading to hypoglycemia. Immunosuppressants: Berberine’s impact on the immune system may interfere with the action of immunosuppressive drugs. Anticoagulants/Antiplatelet Drugs: Berberine may affect blood clotting, potentially increasing the risk of bleeding when taken with these medications. Cyclosporine: Concurrent use with cyclosporine should be avoided, as berberine can interact with this medication. Always inform your healthcare provider about any supplements or herbal remedies you are taking to ensure there are no adverse interactions with your prescribed medications. Are there any adverse effects of Berberine during pregnancy? While berberine itself is generally considered safe for adults, its safety during pregnancy is not well-established. It is crucial for pregnant individuals to exercise caution and adhere to the following guidelines: Avoid During Pregnancy: Berberine-containing supplements, like goldenseal, should be avoided during pregnancy due to insufficient evidence of their safety. Consult Healthcare Professional: Pregnant individuals should consult their healthcare professional before using berberine or any herbal supplements to assess potential risks. Risk of Kernicterus: Giving goldenseal (containing berberine) to newborns could trigger or worsen jaundice and increase the risk of kernicterus, a potentially life-threatening condition. As with any supplement or medication, seeking professional medical advice during pregnancy is essential to ensure the health and safety of both the mother and the unborn child. Best Sources of Berberine Berberine occurs naturally in various plants. If you’re considering incorporating berberine into your routine, here are some excellent natural sources: Barberry (Berberis vulgaris): The bark and roots of the barberry plant contain significant amounts of berberine. Oregon Grape (Mahonia aquifolium): This plant, particularly its roots, is another rich source of berberine. Goldenseal (Hydrastis canadensis): While also a source of berberine, pregnant individuals should avoid it due to potential risks. Chinese Goldthread (Coptis chinensis): Commonly used in traditional Chinese medicine, the rhizomes of this plant are a rich berberine source. Tree Turmeric (Berberis aristata): Found in the Himalayan region, this plant’s roots contain berberine. When considering berberine supplementation, opting for natural sources or consulting with a healthcare professional can help ensure a safe and balanced approach to its consumption. Conclusion In conclusion, berberine stands as a potent natural compound with diverse health benefits. From blood sugar control to potential anticancer effects, its multifaceted impact is promising. However, users should exercise caution, especially concerning dosage and potential interactions. Frequently Asked Questions (FAQs) Question: Is berberine safe for long-term use? Berberine’s long-term safety is still under research. While generally safe, it’s advisable to consult a healthcare professional. Question: Can berberine cause digestive issues? Yes, higher doses may lead to gastrointestinal side effects like diarrhea, constipation, and bloating. Question: What is the recommended dosage of berberine? A standard dose ranges from 900-2,000mg a day, divided into three to four doses. Question: Does berberine interact with medications? Yes, berberine may interact with medications, especially those related to blood sugar. Question: How should berberine be taken for optimal results? Berberine is best taken with meals to leverage the blood glucose and lipid spike associated with eating. How Much Berberine Should I Take? Understanding the optimal dosage is crucial. A standard daily dose ranges from 900-2,000mg, divided into three to four doses. Taking berberine with meals maximizes its benefits on blood glucose and lipid levels. Question: Does Berberine Aid Weight Loss? Research suggests that unpacking the potential impact

Many patients and consumers struggle to pay for the rising cost of prescription medications. As the expense of drugs continues to climb, more and more people are finding themselves unable to receive the vital treatments they need. Thankfully, there are ways that you can advocate for lower drug prices so that you can have access to affordable medicines. In this blog post, we will discuss various strategies that patients and consumers can use to work towards lower drug prices in their local area. By getting involved with community advocacy initiatives and taking part in grassroots campaigns geared at lowering costs, you can create a healthier future for everyone who requires medicine. Overview of the drug pricing system The drug pricing system has been a hot topic in recent years, with many people concerned about the high cost of medications. One reason for these high prices is the complex system used to set drug prices. Manufacturers must account for the costs of research and development, production, marketing, and distribution when pricing their products. Additionally, insurance companies and government programs negotiate different prices for each drug, creating a patchwork system where the same medication can have vastly different prices depending on the patients insurance plan. While efforts to reform the drug pricing system continue, it is clear that finding a solution will require a comprehensive understanding of the many factors that contribute to high drug costs. Comparing prices at different pharmacies When it comes to purchasing medication, its important to do your research and compare prices at different pharmacies. By taking the time to explore your options, you may be able to save a significant amount of money. Additionally, its worth investigating whether there is a generic version of the drug you need, as this can often be a more cost-effective option. Finally, be sure to check whether there are any patient assistance programs available that could help offset the cost of your medication. For example, if you need amoxicillin, it’ll cost an average of $7.43 for a 1-month supply – but by doing your due diligence and exploring these options, you may be able to find it for even less. Asking your doctor or pharmacist to help you find lower-cost drugs Taking care of your health doesn’t have to be expensive. If you’re struggling to afford prescription medication, it’s worth speaking with your healthcare provider to explore your options. Asking your doctor or pharmacist about lower-cost drugs may lead you to discover generic alternatives or other affordable options. These professionals have wealth of knowledge when it comes to medication and can advise you on the best course of action for your situation. Don’t let the cost of medication prevent you from getting the care you need – start a conversation with your healthcare provider today. Speaking up in support of drug price reforms The soaring cost of prescription drugs is a hot topic that has affected millions of patients and consumers across the country. However, recently proposed legislation promises to bring about significant change in the pricing and regulation of drugs. As responsible citizens, it’s our civic duty to educate ourselves about these changes and advocate for drug price reforms by contacting our state representatives. This type of outreach not only helps reduce costs but also ensures that we have access to the medications we need without undue financial strain. Let’s take action and make our voices heard in support of these vital drug price reforms. Taking advantage of online resources In today’s technology-driven world, the internet has become a valuable tool for virtually anything. From shopping to communication, we rely on it almost every day. One of the most useful aspects of the internet is its wealth of resources available to anyone with a computer or a smartphone. It is especially true when it comes to healthcare. With online resources, it’s easier than ever to research the cost of different medications. By using these resources, you can find the best deal for any medication you need to take. It can save you a significant amount of money, which is especially important for people on a limited budget. So go ahead and take advantage of these resources – your wallet will thank you! Accessing prescription assistance programs When it comes to affording prescription drugs, many Americans find themselves struggling with the high costs. Fortunately, there are prescription assistance programs available to those in need. These programs offer various services such as discounts, subsidies, and even free medication. Accessing these programs may seem intimidating, but it doesn’t have to be. Many pharmaceutical companies offer assistance programs. There are also nonprofit organizations dedicated to helping patients navigate the system. It’s important to research and explore your options to find the program that best suits your needs. Don’t let the high costs of medication stand in the way of your health – seek out prescription assistance programs today. Keeping tabs on industry news With rising drug prices, it’s important to stay informed about the issue and what measures are being taken to make medications more affordable. Keeping tabs on industry news can help you understand why drug prices are increasing and what solutions are being proposed. Additionally, taking the time to educate yourself on initiatives to make medications more affordable can help you advocate for yourself or loved ones who may be struggling financially to access necessary treatments. By staying informed, you can take an active role in combating the issue of rising drug prices and promoting access to affordable healthcare for all. In conclusion, it is important to remember that researching the drug you need, asking your doctor or pharmacist for help finding lower-cost drugs, speaking up in support of drug price reforms, taking advantage of online resources, and accessing prescription assistance programs can all help lower the cost of necessary medications. Taking these proactive steps allows consumers to get quality healthcare at an affordable cost while maintaining their financial stability. As the cost of pharmaceuticals continues to rise, access to better quality and lower-cost options becomes even more pertinent. Patients must take the time to educate themselves on their options so they have a clear understanding of what products suit their needs as well as which ones fit into their budgets. The potential savings from doing so make it well worth the effort.