Drugs

Top 100 Drugs Of Choice For Different Diseases

Drugs of choice for different diseases are categorized on the basis of diseases. Following are the most important classes of drugs used as a first choice in the treatment of different diseases.

Drugs Of Choice List in pregnancy

(1)Choloroquine

  • Drug of choice for malaria in pregnancy

(2) Alpha-Methyldopa

  • DoC for hypertension in pregnancy

(3) Femara

  • For breast cancer .

(4) Labetalol

  • For hypertensive crisis in pregnant women.

(5) Acetaminophen

  • Analgesic DOC

(6) Phenobarbitone

  • For epilepsy in pregnant women.

(7) Doxylamine & Pyridoxine

  • For nausea in pregnancy

Drugs Of Choice List in infections

(8) Penicillin G

Drug of choice in

  • Septicemia,
  • Meningitis,
  • Pericarditis,
  • Endocarditis and
  • Severe pneumonia.

(9) Ampicillin

Drug of choice in

  • Listeria,
  • Enterococcus faecalis.

(10) Vancomycin

Drug of choice for

  • MRSA,
  • Coagulase-negative Staphylococcus,
  • Enterococcus faecium.

(11) Erythromycin

Drug of choice for

  • Corynebacterium

(12) Doxycycline

  • Bacillus anthracis,
  • Borrelia burgdorferi, B.Recurrentis.
  • Chalmydia & Rickettsiae.

(13) Cotrimoxazole

Drug of choice in

  • Nocardia

(14) Azithromycin

Drug of choice in

  • Hemophilus ducreyi &
  • Mycoplasma .

(15) Ceftriaxone

Drug of choice for

  • Proteus,
  • E.coli,
  • Salmonella

(16) Ciprofloxacin (Ciproxin)

Drug of choice for

  • Urinary Tract Infection

(17) Metronidazole

Drug of choice for

  • Bacteriocides

(18) Ceftazidime

DOC for

  • Burkholderia pseudomallei

Drugs Of Choice List for various types of seizures

(19) Valproate

Drug of choice for

  • Tonic seizures
  • Absence seizures
  • Grand mal (GTCS)
  • Clonic seizures
  • Atonic seizures
  • Myoclonic seizures

(20) Carbamazepine

  • Partial seizures

(21) Vigabatrin

  • Infantile spasm with tuberous sclerosis

(22) ACTH

  • Infantile spasm

(23) Lorazepam (IV)

  • Status epilepticus

(24) Diazepam

  • Febrile seizures

(25) Magnesium Sulphate

  • Seizure in eclampsia

Drugs Of Choice List in poisoning

(26) Physostigmine

  • Atropine,
  • Belladonna  &
  • Dhatura poisoning

(27) Atropine

  • Carbamate,
  • Early mushroom poisoning,
  • Organophosphate poisoning.

(28) Flumazenil

  • Benzodiazepine poisoning

(29) Acetylcysteine

  • Acetaminophen poisoning

(30) Naloxone

  • Opioid poisoning

(31) Deferiprone

  • Chronic iron poisoning

(32) Desferrioxamine

  • Acute iron poisoning

(33) Glucagon

  • Beta-blockers poisoning

(34) Amyl nitrate

  • Cyanide poisoning

Drugs Of Choice List in bronchial asthma

(35) Salbutamol

Salbutamol is the drug of choice for

  • An acute attack of bronchial asthma in normal patient and pregnant women.
  • Exercise & Aspirin-induced acute attack of bronchial asthma.

(36) Ipratropium

  • An acute attack of bronchial asthma during labor.
  • An acute attack of bronchial asthma on beta-blocker therapy.

(37) Corticosteroids

  • Prophylaxis of bronchial asthma,
  • Exercise-induced, and
  • Aspirin-induced asthma.

Drugs Of Choice List In Antimicrobials Prophylaxis

(38) Ampicillin

  • Group B streptococcus infection

(39) Amoxicillin

  • Endocarditis and Otitis media

(40) Azithromycin

  • Mycobacterium avium complex (MAC) Pertussis

(41) Benzathine penicillin

  • Rheumatic fever

(42) Procaine Penicillin

  • Gonorrhea and syphilis

(43) Tetracycline

  • Rickettsial infection and plague.

(44) Cefazoline

  • Surgical Prophylaxis

(45) Doxycycline

  • Anthrax

(46) Trimethoprim and sulphamethoxazole

  • Toxoplasmosis,
  • Pneumocystis service UTI

(47) Rifampicin

  • Hemophilus influenza type B.

(48) Oseltamivir

  • Influenza Type A & B.

Anesthetic Drugs Of Choice List

(49) Propofol

  • Daycare

(50) Sevoflurane

  • Congenital heart disease,
  • ASD,VSD,PDA

(51) Etomidate

  • Ischemic heart disease

(52) Ketamine

  • Asthma and COPD
  • Shock
  • CHF, and
  • congenital heart disease (Right to left shunt)

(53) Thiopentone

  • Epilepsy
  • Thyrotoxicosis

(54) Methohexitone

  • Electroconvulsive therapy

(55) Isoflurane

  • Cardiac surgery
  • Neurosurgery
  • For producing deliberate hypotension

Drugs Of Choice List in Endocrinological Disorders

(56) Insulin

  • Type 1 DM
  • Diabetes Mellitus in pregnancy.
  • Diabetic Ketoacidosis.
  • Uncontrolled DM.

(57) Metformin

  • Type 2 DM
  • Diabetes mellitus in obesity

(58) Sildenafil

  • Erectile Dysfunction

(59) Hydrocortisone

  • Acute and chronic adrenal insufficiency.

(60) Nateglinide

  • Postprandial hyperglycemia.

(61) Methotrexate

  • Ectopic pregnancy

(62) Oxytocin

  • Postpartum hemorrhage
  • Induction of labor

(63) Cabergoline

  • Acromegaly
  • Hyperprolactinemia.

(64) Finasteride

  • Anogenital alopecia.

(65) Alendronate

  • Osteoporosis

Drugs of choice in fungal infections

(66) Amphotericin B

Amphotericin B is the drug of choice in

  • Meningeal histoplasmosis
  • Endocarditis by candida
  • Sever or CNS blastomycosis
  • Induction  cryptococcal meningitis(For 2 weeks)
  • Exserohium

(67) Fluconazole

  • Candida albicans
  • Maintainance in cryptococcal meningitis

(68) itraconazole

  • Nonmeningeal histoplasmosis
  • Sporotrichosis
  • Para Coccidioidomycosis
  • Mild or non-CNS blastomycosis
  • Chromoblastomycosis
  • Penicillium mameffei

(69) Prednisolone+itraconazole/Voriconazole

  • Allergic bronchopulmonary aspergillosis.

(70) Caspofungin

  • Candida glabrate,and
  • Candida krusei.

Drugs of choice in gastrointestinal disorders

(71) PPIs (Proton Pump Inhibitors)

  • Gastric ulcer,
  • Duodenal ulcer,
  • stress ulcer,
  • NSAIDs-induced ulcer.
  • GERD,& Zollinger Ellison syndrome.

(72) Metoclopramide

  • A migraine associated or drug or disease associated vomiting

(73) Domperidone

  • Levodopa-induced vomiting

(74) Ondansetron

  • Postoperative or radiation-induced vomiting

(75) 5HT3 antagonist

  • Cisplatin-induced early vomiting

(76) Lactulose

  • Hepatic encephalopathy

(77) Methylnaltrexone

  • Opioid-induced constipation

(78) Octreotide

  • Diarrhea in carcinoid syndrome

Drugs of choice in Hematological Disorders

(79) Warfarin

  • DVT prophylaxis
  • Chronic atrial fibrillation in mitral stenosis,
  • Advanced kidney disease, and
  • mechanical prosthetic heart valves

(80) Heparin+Warfarin

  • Initiation of therapy in DVT.

(81) Vitamin K

  • Warfarin overdose

(82) Protamine

  • Heparin overdose

Drugs of Choice in Hypertension

(83) Thiazide diuretics

  • Hypertension

(84) Prazosin

  • Hypertension With BPH

(85) Beta Blockers

  • Hypertension with ischemic heart disease.(Angina)

(86) ACE inhibitors

  • Hypertension with chronic kidney diseases.

(87) Alpha methylDopa

  • Hypertension in pregnancy

(88) Phentolamine

  • Hypertensive emergencies with cheese reaction

(89) Nitroprusside+Esmolol

  • Hypertensive emergencies in aortic dissection.

(90) Labetalol

  • Hypertensive emergencies in pregnancy.

Drugs of choice in shock

(91) Adrenaline

  • Anaphylactic shock

(92) Dopamine or noradrenaline

  • Cardiogenic shock

(93) Phenylephrine

  • Distributive shock

(94) Prazosin

  • Secondary shock

(95) Dopamine

  • Shock with oliguria

(96) Corticosteroids

  • Shock due to adrenal insufficiency

Drugs of choice For viral diseases

(97) Ribavirin

  • Viral hemorrhagic fever
  • Measles
  • Respiratory syncytial virus(in high-risk patient

(98) Zanamivir

  • Oseltamivir-resistant influenza
  • Oseltamivir
  • Seasonal influenza and avian influenza (bird flu)

(99) Acyclovir

  • Herpes simplex and varicella.
  • Valacyclovir
  • Acute herpes zoster.

(100) Gancyclovir

  • Cytomegalovirus retinitis.

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8 Comments

  1. Thanks for your efforts but a lot of therapeutic areas you mentioned have now more preferable drugs than what you mentioned.

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