1. Adrenergic Antagonists

Alpha Adrenergic Antagonists

They can be classified into three groups;

List of Drugs 

Mainly Alpha 1 antagonists

  • Prazosin
  • Doxazosin
  • Terazosin
  • Tamsulosin
  • Alfuzosin
  • Indoramin
  • Urapidil

Mainly Alpha 2 Antagonists:

  • Yohimbine
  • Tolazoline

Alpha 1 And Alpha 2 Antagonists:

  • Phenoxybenzamine
  • Phentolamine

Beta Adrenergic Antagonists

Beta 1 And Beta 2 Antagonists

  • Propranolol
  • Pindolol
  • Penbutolol
  • Nadolol
  • Carteolol
  • Timolol
  • Sotalol

Mainly Beta 1 Antagonists

  • Acebutolol
  • Atenolol
  • Alprenolol
  • Betaxolol
  • Celiprolol
  • Metoprolol
  • Esmolol
  • Nebivolol

2. Adrenergic Agonists

Direct action

These drugs act directly on one or more adrenergic receptors. According to receptor selectivity they are two types:

Non-selective: drugs act on one or more receptors; these are:

List of Drugs 

  • Adrenaline (almost all adrenergic receptors).
  • Noradrenaline (acts on α1, α2, β1).
  • Isoprenaline (acts on β1, β2, β3).
  • Dopamine (acts on α1, α2, β1, D1, D2).

Selective: drugs which act on a single receptor only; these are further classified into

List of Drugs 

  • α selective & β selective.
  • α1 selective: Phenylephrine, Methoxamine, Midodrine, Oxymetazoline.
  • α2 selective: α-Methyl dopa, clonidine, brimonidine.
  • β1 selective: Dobutamine.
  • β2 selective: Salbutamol/Albuterol, Terbutaline, Salmeterol, Formoterol, Pirbuterol.

Indirect action

List of Drugs 

  • Amphetamines
  • Cocaine
  • Methylenedioxymethamphetamine (MDMA)
  • Tyramine
  • Nicotine
  • Caffeine
  • Methylphenidate

Mixed action

  • Ephedrine
  • Pseudoephedrine

3.Cholinergic  Agonists

Direct and indirect acting Agonists

List of Drugs

1. Direct Acting Agonist Drugs:

They ARe further divided into two groups

a. Choline Esters

  • Acetylcholine
  • Methacholine
  • Carbachol
  • Bethanechol

b. Cholinomimetic alkaloids

  • Muscarine
  • Nicotine
  • Pilocarpine
  • Lobeline

2. Indirect Acting Drugs:

List of Drugs 

a. Reversibly Acting:

  • Neostigmine
  • Physostigmine
  • Demecarium
  • Pyridostigmine
  • Ambenonium

b. Irreversible Acting:

  • Echothiophate
  • Parathione
  • Malathione
  • Tetra ethyl Pyrophosphate

4.Cholinergic Antagonists

List of Drugs 

Antimuscarinic agents

  • Atropine
  • Benztropine
  • Biperiden
  • Chlorpheniramine
  • Dicyclomine
  • Dimenhydrinate
  • Diphenhydramine
  • Doxepin
  • Doxylamine
  • Glycopyrrolate
  • Ipratropium
  • Orphenadrine
  • Oxitropium
  • Oxybutynin
  • Propantheline bromide
  • Tolterodine
  • Tiotropium
  • Trihexyphenidyl
  • Scopolamine
  • Solifenacin
  • Tropicamide

Antinicotinic agents

  • Bupropion
  • Dextromethorphan
  • Doxacurium
  • Hexamethonium
  • Mecamylamine
  • Tubocurarine

 

5. Anti Anginal Drugs

List of Drugs 

a) Organic Nitrates

  • Nitriglycerin
  • Isosorbide Dinitrate
  • Isosorbide Mononitrate
  • Amyl nitrite

b) Calcium Channel Blockers

List of Drugs 

Further Divided Into

1. Dihydropyridine

  • Nifedipine
  • Nicardipine
  • Amlodipine
  • Nisoldipine
  • Nitrendipine
  • Nimodipine

2. Miscellaneous Drugs

  • Verapamil
  • Diltiazem
  • Bepridil

c) Beta Blockers

Further Divided Into

1. ß 1 + ß 2 Antagonists

  • Propranolol
  • Penbutolol
  • Sotalol
  • Pindolol
  • Timolol

2. ß 1 Selective Antagonist

  • Metoprolol
  • Atenolol
  • Esmolol
  • Acebutolo
  • Betaxolol

6. Drugs Used For Congestive cardiac failure

Drugs Used For Congestive Cardiac Failure or chf medications are ,

1)Drugs used to decrease preload:
A)Diuretics
B)organic nitrate
2)Drugs which decrease after load
A)Hydralazine
B)Minoxidil
3)Drugs which decrease both preload and afterload:
A)Captopril
B)Enalapril
C)Lisinopril
D)Fosinopril
E)Quinapril
4)Positive ionotropic drugs:
They can be further divided into three groups;
1)Cardiac glycosides:
A)Digoxin
B)Digitoxin
C)Ouabin
D)Lanatoside.
2)Phosphodiestrase inhibitors:
A)inamrinonone (Amrinone)
B)Milrinone
3)Sympathomimetics:
A)Dopamine
B)Dobutamine
C)Depoxamine
D)Xamoterol

7. Antiplatelet Drugs

Antiplatelet List of drugs include:

  • Anagrelide
  • Aspirin
  • clopidogrel
  • prasugrel
  • ticagrelor
  • tirofiban
  • vorapaxar
  • dipyridamole

8.  Anticoagulant Drugs

List of drugs in this class include:

  • warfarin
  • dabigatran
  • edoxaban
  • rivaroxaban
  • apixaban

9. Diuretics

Thiazides diuretics

List of Drugs 

  • Chlorothiazide
  • Chlorthalidone
  • Indapamide
  • Hydrochlorothiazide
  • Methyclothiazide
  • Metolazone

Loop diuretics

List of Drugs 

  • Bumetanide
  • Furosemide
  • Ethacrynate
  • Torsemide

Potassium sparing diuretics

  • Amiloride hydrochloride
  • spironolactone
  • triamterene

10.Statins

Statins that are approved for use in the U.S. include:

List of Drugs 

  • Atorvastatin
  • Fluvastatin
  • Lovastatin
  • Pravastatin
  • Rosuvastatin
  • Simvastatin
  • Pitavastatin

11.Thrombolytic Drug

Thrombolytic List of Drugs  — include:

  • Anistreplase
  • Reteplase
  • Streptokinase, kabikinase
  • t-PA (class of drugs that includes Activase)
  • TNKase (tenecteplase)
  • Abbokinase, Kinlytic (rokinase)

12. Sedative Hypnotic

1. Sedative Anxiolytic Drugs 

Benzodiazepines List of Drugs 

  • Alprazolam
  • Bromazepam
  • Chlordiazepoxide
  • Clonazepam
  • Clorazepate
  • Diazepam
  • Flurazepam
  • Lorazepam
  • Oxazepam
  • Temazepam
  • Triazolam

Barbiturates

barbiturates include:

  • Phenobarbital
  • Mephobarbital
  • Amobarbital sodium
  • Butabarbital sodium
  • Secobarbital sodium

2. Non Sedative 

  • Buspirone
  • Gepirone
  • Ipsapirone
  • Tandospirone

13. Antidepressants

List of Drugs

1. Tricyclic Antidepressant

  • Amitriptyline
  • Amoxapine
  • Desipramine
  • Doxepin
  • Imipramine
  • Nortriptyline
  • Protriptyline
  • Trimipramine

2. Selective serotonin reuptake inhibitors (SSRIs)

  • Citalopram
  • Escitalopram
  • Paroxetine
  • Fluoxetine
  • Fluvoxamine
  • Sertraline

3. Serotonin–norepinephrine reuptake inhibitors (SNRIs)

  • Desvenlafaxine
  • Duloxetine
  • Levomilnacipran
  • Milnacipran
  • Venlafaxine

4. Serotonin modulators and stimulators (SMS)

  • Vilazodone
  • Vortioxetine

5. Norepinephrine reuptake inhibitors (NRIs)

  • Reboxetine
  • Teniloxazine
  • Viloxazine

6. Monoamine Oxidase Inhibitors

  • Isocarboxazid
  • Phenelzine
  • Selegiline
  • Tranylcypromine

14. Antipsychotic Drugs

  • Aripiprazole
  • Asenapine
  • Cariprazine
  • Clozapine
  • Lurasidone
  • Olanzapine
  • Quetiapine
  • Risperidone
  • Ziprasidone

15. Anti epileptic Drugs

Absence seizures (including typical and atypical absences): (List of Drugs)

  • Acetazolamide
  • Clonazepam
  • Ethosuximide
  • Lamotrigine
  • Sodium valproate

Atonic seizures:

  • Phenobarbital
  • Phenytoin
  • Primidone
  • Sodium valproate

Catamenial seizures (menstrual-related):

  • Acetazolamide
  • Clobazam

Cluster seizures:

  • Clobazam

Episodic disorders:

  • Acetazolamide

Dravet syndrome (severe myoclonic epilepsy in infancy or SMEI):

  • Stiripentol

Focal (partial) seizures:

  • Acetazolamide
  • Carbamazepine
  • Clobazam
  • Clonazepam
  • Eslicarbazepine acetate
  • Gabapentin
  • Lacosamide
  • Lamotrigine
  • Levetiracetam
  • Oxcarbazepine
  • Perampanel
  • Phenobarbital
  • Phenytoin
  • Pregabalin
  • Primidone
  • Retigabine
  • Sodium valproate
  • Tiagabine
  • Topiramate
  • Vigabatrin
  • Zonisamide

Focal (partial) seizures with secondary generalisation:

  • Gabapentin
  • Lacosamide
  • Levetiracetam
  • Perampanel
  • Phenobarbital
  • Phenytoin
  • Pregabalin
  • Primidone
  • Retigabine
  • Sodium valproate
  • Tiagabine
  • Topiramate
  • Vigabatrin
  • Zonisamide

Focal seizures with secondary generalised tonic clonic seizures:

  • Carbamazepine
  • Eslicarbazepine acetate
  • Lamotrigine
  • Oxcarbazepine

Infantile spasms:

  • Nitrazepam
  • Sodium valproate
  • Vigabatrin

Juvenile Myoclonic Epilepsy (seizures related to):

  • Levetiracetam

Lennox-Gastaut syndrome (seizures related to):

  • Lamotrigine
  • Rufinamide
  • Topiramate

Myoclonic seizures:

  • Clonazepam
  • Ethosuximide
  • Phenobarbital
  • Phenytoin
  • Primidone
  • Piracetam
  • Sodium valproate

Tonic seizures:

  • Phenobarbital
  • Phenytoin
  • Primidone
  • Sodium valproate

Tonic clonic seizures:

  • Acetazolamide
  • Carbamazepine
  • Clobazam
  • Clonazepam
  • Eslicarbazepine acetate
  • Lamotrigine
  • Phenobarbital
  • Phenytoin
  • Primidone
  • Sodium valproate
  • Topiramate

West Syndrome with Tuberous Sclerosis:

  • Vigabatrin

 

16. Anesthetic Drugs

List of Drugs 

Local anesthetics

  • Procaine
  • Amethocaine
  • Lidocaine (also known as lignocaine)
  • Prilocaine
  • Bupivacaine
  • Levobupivacaine
  • Ropivacaine
  • Mepivacaine
  • Dibucaine
  • Cocaine

General anesthetics

Inhaled agents

  • Desflurane
  • Enflurane
  • Halothane
  • Isoflurane
  • Methoxyflurane
  • Nitrous oxide
  • Sevoflurane
  • Xenon
  • Cocaine

Intravenous agents (non-opioid)

  • Barbiturates
  • Amobarbital (trade name: Amytal)
  • Methohexital (trade name: Brevital)
  • Thiamylal (trade name: Surital)
  • Thiopental (trade name: Penthothal, referred to as thiopentone in the UK)
  • Benzodiazepines
  • Diazepam
  • Lorazepam
  • Midazolam
  • Etomidate
  • Ketamine
  • Propofol

 

17. Non Steroidal Anti-inflammatory Drugs

List of Drugs 

  • Aspirin
  • Celecoxib
  • Diclofenac
  • Diflunisal
  • Etodolac
  • Ibuprofen
  • Ketoprofen
  • Ketorolac
  • Nabumetone
  • Naproxen
  • Oxaprozin
  • Piroxicam

 

18. Disease Modifying Anti Rheumatic Drugs

List of Drugs 

a) Immunosuppressive Drugs

  • Methotrexate
  • Cyclophophamide
  • Azathioprine
  • Chlorambucil
  • Cyclosporine
  • Mycophenolate mofetil
  • Leflunamide

b) Gold Compounds

  • Aurothiomalate
  • Aurothioglucose
  • Auranofin

c) Aminoquinolines

  • Chloroquine
  • Hydroxychloroquine alpha

19. Antigout Drugs

Further Divided Into

Drugs For the treatment of Acute Attack of Gout

  • Colchicine
  • NSAIDs

Drugs For the Prevention Of Gout

  • Uricosuric Drugs ( Probencid, Sulphinopyrazine
  • Inhibitors of Uric Acid synthesis (allopurinol, Febuxostat

 

20. Anti-migraine Drugs

Drugs For the Treatment OF Acute Attack

1. 5-HT1 Agonists

  • Sumatriptan
  • Zolmitriptan
  • Naratriptan
  • Rizatriptan

2. Other Drugs

  • Ergotamine
  • Dihydroergotamine
  • NSAIDs
  • Paracetamol
  • Opioids

 

Prophylactic Drugs

 

  • Propranolol
  • Aspirin
  • Pizotifen
  • Cyproheptadine
  • Amitriptyline
  • Imipramine
  • Fluoxetine
  • Sertraline
  • Methysergide
  • Flunarizine
  • Clonidine

21. Antimicrobial Drugs

1. Beta Lactam Antimicrobials

List of Drugs In This class Include

  • Penicillin
  • Cephalosporins
  • Monobactams
  • Carbaphenems

Penicillin

Narrow Spectrum Penicillin

Further Classified into two

a) Penicillinase Sensitive Penicillin

  • Penicillin G (Benzyl Penicillin)
  • Penicillin V

b) Penicillinase Resistant Penicillin

  • Nafcillin
  • Oxacillin
  • Cloxacillin
  • Dicloxacillin
  • Flucloxacillin
  • Methicillin

c) Broad Spectrum Penicillin

This is further divided into two

1. Aminopenicillin

  • Ampicillin
  • Amoxicillin
  • Bacampicillin
  • Talampicillin

2. Antipseudomonal Penicillin

They are further divided into two

1. Carboxypenicillin

  • Carbencillin
  • Ticarcillin

2. Ureidopenicillins

  • Azlocillin
  • Mezlocillin
  • Piperacillin

2. Fluoroquinolones ;

  • (A)First Generation e.g Nalidix acid
  • (B)Second Generation e.g Ciprofloxacin,Norfloxacin and ofloxacin.
    Norfloxacin don’t absorb very well and they are not used most commonly While ciprofloxacin is the most commonly used drug in this class.
  • (C)Third Generation  E.g Levofloxacin
  • (D)Fourth Generation : Moxifloxacin

3. Cephalosporins

First-Generation Cephalosporins

  • cefadroxil
  • cefazedone
  • cefazolin
  • cephalexin
  • cephalothin
  • cephradine
  • cephaloridine
  • cephapirin

Second-Generation Cephalosporins

  • cefaclor
  • cefamandole
  • cefprozil
  • cefuroxime
  • loracarbef
  • cephalosporins

Third-Generation Cephalosporins

  • cefcapene
  • cefdinir
  • cefditoren
  • cefetamet
  • cefixime
  • cefmenoxime
  • cefoperazone
  • cefotaxime
  • cefpiramide
  • cefpodoxime
  • cefsulodin
  • ceftibuten
  • ceftizoxime
  • ceftriaxone

Fourth-Generation Cephalosporins

  • cefepime
  • cefluprenam
  • cefozopran
  • cefpirome
  • cefquinome

3. Sulfa Drugs

List of Drugs in this class include:

  • Co-Trimoxazole
  • Sulfadiazine
  • Sulfamethoxazole
  • Trimethoprim-Sulfamethoxazole
  • Trimethoprim
  • Sulfasalazine
  • Sulfisoxazole

5. Antitubercular Drugs

“first line” drugs

  • Isoniazid
  • Rifampicin
  • Pyrazinamide
  • Ethambutol
  • and Streptomycin

Second Line Drugs

  • Para aminosalicylic Acid
  • Amikacin
  • Capreomycin
  • Ciprofloxacin
  • Clofazimine
  • Cycloserine
  • Ethionamide
  • Levofloxacin
  • Rifabutin
  • Rifapentine

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