Tranexamic acid (Brand: Transamin) prevents enzymes in the human body from breaking down blood clots.
Transamin is traditionally used in the treatment of heavy menstrual bleeding. This medicine won’t treat premenstrual syndrome (PMS).
It’s usually taken with or without meals three times per day for up to 5 times during monthly menstruation. You should start taking this medicine each month as soon as your period begins. Don’t take tranexamic acid whenever you don’t have a time. Require tranexamic acid at roughly the very same times every day you are supposed to get a dose.
Tranexamic acid (Transamin Capsules) are usually taken 3 times each day for a max of 4 times. You begin taking the pills once your period begins.
Tranexamic Acid Uses
Transamin Capsule can be utilized for the treatment, prevention, control, & improvement of the following ailments, ailments and symptoms:
- Heavy menstrual bleeding
- Blood clotting issues
- Swelling in many different body components
- Acute reduction of blood
- Transamin Capsule might also be used for purposes not listed here.
Mechanism of Action
- Tranexamic acid competitively inhibits activation of plasminogen hence decreasing conversion of plasminogen into plasmin (fibrinolysin), an enzyme which degrades fibrin clots, fibrinogen, and other plasma proteins, for example, procoagulant factors V and VIII.
- Tranexamic acid also directly inhibits plasmin action, but higher doses are needed than are required to cut back plasmin formation.
Side effects
Tranexamic acid can cause unwanted effects. Tell your doctor if any of these symptoms are severe or don’t go off:
- Headache
- Fatigue
- Sinus pain
- Spine pain
- Stomach pain
- Bone, jointpain or muscle soreness
Some side effects may be severe like
- Infection
- Rash
- Itching
- Trouble swallowing or breathing
swelling of the face, tongue, throat, lips, eyes, hands, feet, ankles, or lower legs - Hoarseness
- Changes in eyesight, such as colour vision
- Chest pain
- shortness of breath
- Leg swelling, swelling, tenderness, redness, or heat
Contraindications
Transamin is contraindicated in the following medical conditions
- It is contraindicated in case of hypersensitivity and allergic reaction to this drugs or any other excipients.
- Active thromboembolic disease.
- Fibrinolytic states following consumption coagulopathy.
- Severe renal impairment due to danger of accumulation.
Tranexamic acid in pregnancy & breast-feeding
It’s not understood if tranexamic acid will harm an unborn baby. Tell your doctor if you’re pregnant or intend to become pregnant while using this medicine.
Tranexamic acid may pass into breast milk and might harm a nursing baby. Don’t use this medicine without telling your doctor if you’re breast-feeding a infant.
Drug interactions
Tell your doctor about all other Medications you use, especially:
- Hormonal birth control (like birth control pills, implants, injections, skin spots, and vaginal rings);
- Any kind of medication to cure a bleeding event or a blood clot; or
factor IX (Bebulin VH, Konyne 80, Profilnine SD, Proplex T, and many others ). - Chemotherapy medicine to treat leukemia;
- Tretinoin
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It may interact with Acetaminophen, Albuterol, Ascorbic acid, Aspirin, Clopidogrel, Cyclobenzaprine, Diazepam, Diphenhydramine, Epinephrine and Esomeprazole.
This is not a complete list of interactions. Consult your GP before using Transamin with other drugs.
Tranaxemic acid (Transamin) Dose
Oral route:
- Usual Dose: 1-2 capsules (250 mg) 3 times per day or one tab (500 milligrams ) 3-4 times each day.
- Menorrhagia (Heavy Menstrual Bleeding): 4 capsules or two tablets (1 g) 3 times each day beginning on the 1st day of the interval for days of heavy stream.
- Dose for intravenous or intramuscular injection is 2-10 amps (10-50 ml) (500-2500 milligrams ) are awarded by Intravenous drip infusion, if needed.
- The dose hasn’t been established in pediatric patients. It might be dangerous for the child. It’s always important to completely understand the protection of the medication before using. Please consult with your physician or pharmacist to learn more.