Drugs to avoid during pregnancy

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1)Antibiotics Drugs to avoid during pregnancy Fluoroquinolones (such as ciprofloxacin, ofloxacin, levofloxacin, and norfloxacin) Nitrofurantoin Streptomycin Sulfonamides (such as sulfasalazine and trimethoprim-sulfamethoxazole) Tetracycline Abnormalities Caused By These Drugs Possibility of bone and joint abnormalities (seen only in animals) 2) Anticonvulsants Drugs to avoid during pregnancy Carbamazepine Phenobarbital Phenytoin Valproate Abnormalities Caused By These Drugs Bleeding problems in the newborn. This Problem Can be prevented by Taking Vitamin K Orally 30 Days Before Delivery Cause Risk of birth defects, including neural tube defects (such as spina bifida) Valproate Cause Some (1%) risk of birth defects, including neural tube defects (such as a meningomyelocele), cleft palate, and defects of face,  the heart, skull, limbs, and  spine 3) Antihypertensives Drugs to avoid during pregnancy a)Angiotensin-converting enzyme (ACE) inhibitors Captopril Benazepril Fosinopril Enalapril Lisinopril Quinapril…
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Drugs Used For Congestive Cardiac Failure/Heart Failure

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To understand how chf medications work we have to first understand the normal physiology of heart.what happens to failing heart and what are the natural ways to avoid heart failure .We will also highlight some chf medications and possible management proctocols . Cardiac/Heart Failure : In Congestive Cardiac/Heart failure the heart fails to supply enough blood to the tissues due to decrease in cardiac out put.cardiac output depends upon the following four factors; 1)Preload 2)After load 3)Force Of heart contractility 4)Heart rate Preload: It can be defined as the volume of blood which flows into the heart and causes its stretch.stretching of the heart upto a certain point increases its force of contraction,as is explained by the frank starling law.thus increase in blood flow to the heart will increase its…
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Top 50 Important Drugs and Their Side Effects

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Nearly All Drugs Both OTC And Prescription Drugs Have Some Kind Of Undesirable Side effects From simple Muscle Pain to Death .Whether they are the simple drug like aspirin to the most sophisticated drugs In the Market , All Drugs Come With Some Minor Or serious Side Effects.Nearly All Drugs Can cause Nausea,Vomiting And For Drugs Used On Skin Will Cause Irritation. Following Are Some Of The Most Commonly Used Drugs And Their Side Effects . 1.Ampicillin- Hypersensitivity 2. Amphotericin.B- Nephrotoxicity 3. Androgen- Virilization 4. Antipsychotics- Sedation, Orthostatic hypotension, Tardive dyskinesia 5. Anti- TB- Hepatotoxicity 6. Aspirin (cox-I Inhibitors)- Hepatotoxicity 7. ACE Inhibitors- Dry Cough 8. Atropine – Dryness of mouth, Blurred vision, Constipation 9. Chlorambucil- Alopecia 10.Celecoxib,Valdecoxib (cox-II Inhibitors)-cardio and Hepatotoxicity 11.Chloroquine – Phototoxicity 12.Chloramphenicol- Grey baby syndrome, Bone  …
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Top 100 Drugs Of Choice For Different Diseases

Top 100 Drugs Of Choice For Different Diseases

Articles, Drugs
Drugs Of Choice For Different Diseases are categorized on the basis of diseases.Following are the most important classes of drugs used as a first choice in the treatment of different diseases. Drugs Of Choice List in infections (1)Penicillin G Streptococcus pneumoniae, S.Viridans, Hemolytic Streptococci group A, B, C, G, Staphylococcus (Non-Penicillinase producing) Neisseria meningitidis,Clostridium(ABC)Bacillus Cereus,Actinomyces.Treponema Pallidum, T.Pertene (2)Ampicillin Listeria, Enterococcus faecalis. (3)Vancomycin MRSA, Coagulase-negative Staphylococcus, Enterococcus faecium. (4)Erythromycin Corynebacterium (5)Doxycycline Bacillus anthracis, Borrelia burgdorferi, B.Recurrentis. Chalmydia & Rickettsiae. (6) Cotrimoxazole Nocardia (7) Azithromycin Hemophilus ducreyi & Mycoplasma . (8) Ceftriaxone Proteus,E.coli,Salmonella (9)Carbapenems Serratia,Enterobacter,Acinetobacter (10)(Metronidazole Bacteriocides (11)Ceftazidime Burkholderia pseudomallei Drugs Of Choice List in pregnancy (12)Choloroquine Drug of choice for malaria in pregnancy (13) Alpha-Methyldopa DoC for hypertension in pregnancy (14)Heparin DOC for anticoagulation in pregnancy. (15)Labetalol DOC for hypertensive crisis in pregnant…
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Proton Pump Inhibitors (PPIs)

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What are proton pump inhibitors and Their Mechanism ? Proton pump inhibitors (PPIs) reduce the production of acid by obstruction the enzyme in the wall of the stomach that produces acid. Acid is important for the formation of most ulcers in the esophagus, stomach, and duodenum, and therefore the reduction of acid with PPIs prevents ulcers and permits any ulcers that exist within the esophagus, stomach, and duodenum to heal. What diseases do PPIs treat? Proton pump inhibitors are used for the prevention and treatment of acid-related conditions such as: For Treatment Of Esophageal duodenal and stomach ulcers NSAID-associated ulcer For Other Ulcers For The Treatment Of Gastroesophageal reflux disease (GERD) And for Zollinger-Ellison syndrome They also are used in combination with antibiotics for eradicating Helicobacter pylori, a bacterium that together with acid causes ulcers of the stomach and duodenum.cs for eradicating H. pylori, a bacterium that together with acid causes ulcers of the stomach…
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Paracetamol

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What is Paracetamol/Acetaminophen? Acetaminophen belong to a class of drug Called analgesic(pain reliever) and antipyretics(fever reducer).It is  used to treat different Medical conditions such as headache, muscle aches, arthritis, backache, toothaches, colds,menstrual periods and fevers.The FDA approved acetaminophen in 1951. Mechansim Of Action Acetaminophen is assumed to act primarily within the central nervous system, increasing the pain threshold by inhibiting each isoforms of cyclooxygenase, COX-1, COX-2, and COX-3 enzymes involved in prostaglandin (PG) synthesis. in contrast to NSAIDs, acetaminophen doesn't inhibit cyclooxygenase in peripheral tissues and, thus, has no peripheral anti-inflammatory affects. whereas acetylsalicylic acid acts as an irreversible inhibitor of COX and directly blocks the enzyme's active site, studies have found that Tylenol indirectly blocks COX, and that this blockade is ineffective within the presence of peroxides. This would possibly make a…
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Scientists Developed A New Medical  Device To  Diagnose A Dozen  Different Diseases

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Average people might sooner or later be able to use a Star Trek-inspired home medical device to diagnose a dozen completely different diseases and track five major important signs, all without having to draw blood or visit a doctor's office. Engineers developed the DxtER device as a part of a contest to make a modern version of the "tricorder" that Dr. Leonard "Bones" McCoy waved over patients on the starship Enterprise to diagnose sicknesses. The DxtER combines an array of various sensors with intelligent diagnostic computer code in a package weighing but five pounds, same technology design skilled Philip Charron, a member of the team that created the device., Charron said the DxtER combines: A wrist and hand detector that checks blood pressure, glucose levels, hemoglobin, white blood cell counts and blood oxygen levels. A spirometer, that could be a device to measure the air capability of the lungs once people breathe into the machine. A chest sensor for observation heart rate, respiration, and temperature. A digital stethoscope that listens to sounds from breathing. All of these devices act with diagnostic software running on a tablet. A person using the DxtER at home will check themselves for anemia, tract infections, diabetes, atrial fibrillation(irregular heartbeat), sleep disorder, COPD (chronic obstructive pulmonary disease), pneumonia, ear infection, pertussis, high blood pressure, mononucleosis and raised white blood cell counts "A regular consumer will sit down with our device,…
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Quinolones and Fluoroquinolones

Quinolones and Fluoroquinolones

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Quinolones & Fluoroquinolones : One of the most important member of quinolone group of antibiotic was Nalidix Acid.The Problem with this compound was that it was narrow spectrum and it has moderate gram negative activity but it has no gram positive activity.Apart from this issue the nalidix acid was poorly distributed in the body.so with the passage of time scientists added flourine with mother compound i.e Nalidix acid so "a group of antibiotics which are flourinated analogues of nalidix acid are called fluoroquinolones" why they are so important ? A)Very Good Oral Absorption. B)Very good distribution means deep peneteration in the tissues very effiently.because of their deep penetretion they can kill intracellular organisms.e.g chlamydia,TB,Legionella,brucella. C)Newer agents are very broad spectrum. D)They have high potency. E)They are very well tolerated (Very safe…
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Drugs Used In Asthma

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Asthma According To WHO A medical Condition characterized by recurrent attacks of breathlessness and wheezing, which vary in severity and frequency from person to person. In an individual, they may occur from hour to hour and day to day. If you or a loved one has asthma attack, you must understand the most effective asthma treatments for short-run relief and long-term management. Understanding asthma treatments can modify you to work with your asthma doctor to confidently manage your asthma symptoms daily. when you do have an Asthma or asthma symptoms, it is important to understand when to call your doctor to stop an asthma emergency. There are two type of asthma control medications , Short Relief And Long Term Asthma Control Medications. Long-term control medications reduce the inflammation in your…
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Emergency Drugs

Emergency Drugs

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  HYPERTENSIVE EMERGENSIES Systolic Blood PressureMore Than 220 mmHg or diastolic Blood Pressure More Than 120 mmHg with evidence of active end organ damage. SODIUM NITROPRUSSIDE  Dose : 20-300 microgram/ min i.v Because of predictable, instantaneous, titrable and balanced arteriovenous vasodilatory action it is preferred. Toxic in higher dose.And That’s The Reason Proper Monitoring Should Be Done. LABETALOL for pregnancy induced hypertension. ESMOLOL can also be used. If injection is not available Use  Capsule Nifedipine S/L PHENTOLAMINE OR LABETALOL for hypertensive episode in pheochromocytoma, cheese reaction or clonidine withdrawal   DRUGS FOR CARDIOVASCULAR SYSTEM EMERGENCIES CORONARY PAIN SYNDROMES :It is a group of conditions due to decreased blood flow in the coronary arteries such that part of the heart muscle is unable to function properly or dies.It refers to a…
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