Important Information About Mefenamic Acid

Important Information About Mefenamic Acid

Articles, Drugs
Mefenamic Acid Uses Mefenamic acid (Ponstan) is a Fenamic acid derivatives and is employed in the treatment of pain and inflammation in rheumatoid arthritis and osteoarthritis.Mild to moderate pain,Postoperative pain, menorrhagia (Abnormally heavy periods) and dysmenorrhoea (Painful periods),Pain following surgery, And Pain following childbirth. It has less anti-inflammatory and more harmful effects as compare to aspirin and that is why it mustn't be used for more than one week at a time.It is contraindicated in children and disease like inflammatory bowel disease.It is available in Tablets of 250 and 500 mg. Mechanism Of Action Ponstan contain the active ingredient Mefenamic acid-Which is a type of drugs known as a non-steroidal anti-inflammatory drug (NSAID). NSAIDs are used to relieve pain and inflammation.Mefenamic acid binds the prostaglandin synthetase receptors Cox-1 and Cox-2,…
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Beta 2 Agonist Drugs

Beta 2 Agonist Drugs

Articles, Drugs
Beta 2 Agonist Drugs (Selective Beta 2 agonists) are the safest drugs and most effective short acting beta 2 agonist for the treatment of asthma while some long acting beta 2 agonist are added to an inhaled corticosteriod. Less Selective beta 2 agonist such as ephedrine should be avoided if possible. Mainly or Selective Beta 2 Agonists produce bronchodilation and It  include: Salbutamol Terbutaline Fenoterol Ritodrine Salmeterol Formoterol 1. Salbutamol: Uses: It is a selective β² agonist and is mainly used as a bronchodilator in the treatment of asthma for this purpose it is best used by inhalation with the help of an inhalaer or nebulizer .When use by inhaltion a smaller dose of drug is required to produce the maximum effect.0.25-0.5 can be used by subcutaneous,intramuscular or slow intrvenous. It…
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Important Information About Cefixime

Important Information About Cefixime

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Cefixime indications/Uses Cefixime is an orally active third generation cephalosporin antibiotics and is employed to treat certain infections caused by bacteria like bronchitis (infection of the airway tubes leading to the lungs); infections of the ears, throat, tonsils, and urinary tract.gonorrhea (a sexually transmitted disease). it's extremely stable in the presence of beta-lactamase enzymes It works by killing bacterium.Antibiotics like cefixime won't work for colds, flu, or different viral infections. using antibiotics when they aren't required will increase your risk of obtaining an infection later that resists antibiotic treatment. Mechanism Of Action Of Cefixime Cefixime binds to specific penicillin-binding proteins (PBPs) situated inside the bacterial cell wall, inflicting the inhibition of the third and last stage of bacterial cell wall synthesis. Cell lysis is then mediated by bacterial cell wall…
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Important information About Vigabatrin

Important information About Vigabatrin

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Vigabatrin Uses:Vigabatrin is an analogue of gamma aminobutayric acid and  belongs to a group of drugs known as anticonvulsant drugs but it is chemically unrelated to other anticonvulsant drugs.It can be prescribed in combination with other drugs for focal epilepsy with or without secondary generalization.It is also used in partial seizures and as a monotherapy in the treatment of infantile spasm in west's syndrome.Pharmacokinetics:Vigabatrin half life is approximately 6-8 hours but considerable evidence suggest that pharmacodynamic activity of the drug is more prolonged and not well correlated with the plasma half life.Mechansim Of Action:Vigabatrin inhibits irreversibly the enzyme GABA aminotransferase ( enzyme causing metabolism of GABA),Thus, increasing the concentration of GABA at its synapses. It may also work by suppressing repetitive neuronal firing through blocking of voltage-sensitive sodium channels.Side Effects:More…
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Important Information About Sulfamethoxazole Trimethoprim

Important Information About Sulfamethoxazole Trimethoprim

Articles, Drugs
Uses: A combination of two antibiotics: Sulfamethoxazole Trimethoprim is employed to treat a wide range of infections caused by bacteria (such as respiratory, middle ear, urine, and intestinal infections) it's utilized in traveler's diarrhoea, and shigellosis (bacillary dysentery).It is additionally used to stop and treat a particular type of pneumonia (Pneumocystis carinii pneumonia (PCP).This type of respiratory disease occurs more commonly in patients whose immune systems aren't operating normally, like cancer patients, transplant patients, and patients with acquired immune deficiency syndrome (AIDS).This drug shouldn't be utilized in children less than two months of age because of the chance of serious side effects. Mechanism Of Action: Sulfamethoxazole Trimethoprim are normally employed in combination because of their synergistic effects. This drug combination additionally reduces the development of resistance that's seen when either…
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Important Information about Carbimazole

Important Information about Carbimazole

Articles
Carbimazole belong to a group of drugs known as Anti thyroid drugs and is mainly used in the treatment of hyperthyroidism- a condition where in the thyroid gland is hyperactive. It is used to reduce the formation of thyroid hormones.This drug is used for hyperthyroidism either to prepare patient for throidectomy or for long term management. Pharmacokinetics: It is quickly absorbed orally,widely distributed in the body,metabolized in liver, and excreted in urine primarily as metabolites. carbimazole acts largely by getting converted to methimazole in the body. Mechanism Of Action Of Carbimazole: This drug bind to thyroid per oxidase and prevent oxidation of iodide/iodotyrosyl residues, thereby inhibit oxidination of thyrosine in thyroglobulin and also inhibit coupling of iodotyrosine residues to form T3 and T4. Warnings: Do not take Carbimazole if you: are allergic…
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This Iranian Girl undergoes 50 Plastic Surgeries to look like Angelina Jolie Goes very wrong

This Iranian Girl undergoes 50 Plastic Surgeries to look like Angelina Jolie Goes very wrong

Articles
It’s no secret that Angelina Jolie has a massive fan following  on social media and real life but some of which, are true diehard fans.However, one fan in particular seems to have taken her love for Jolie way too far. An Iranian lady has gone viral when claiming she’s had fifty surgeries in a bid to look like her idol Angelina Jolie.   Sahar Tabar claims to be one among the “Tomb Raider” actress’ biggest fans and has aforesaid she “would do anything” to emulate her. The story was quickly picked up by web sites in India, Saudi Arabia, and the U.S , among other countries. Although Sud Info listed Tabar as being 22 years old, other sites have reported that she is only 19. The 19-year-old from Tehran underwent fifty surgeries within…
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Important information about Femara ( Letrozole)

Important information about Femara ( Letrozole)

Articles, Drugs
Letrozole (Brand Name: Femara) is an orally active nonsteroidal compound that reversibly inhibits aromatization all over the body, as well as that within the breast cancer cells, resulting in nearly total estrogen deprivation.It is a selective inhibitor of estrogen formation.it inhibits the estrogen synthesis by inhibition of aromatase enzyme that is crucial for the formation of estrogen.The proliferation of estrogen-dependent breast cancer is suppressed to a greater extent than with tamoxifen. Pharmacokinetics: Letrozole (Femara) is quickly absorbed with 100% bioavailability, Slow metabolism, the large volume of Distribution, and Time half (t½) of approximately 40 hours. Mechanism Of Action (Femara) Letrozole is a Selective nonsteroidal inhibitor of the aromatase enzyme system; it inhibits the conversion of androgens to estrogens.In adult nontumor- and tumor-bearing female animals, letrozole is as effective as ovariectomy…
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Viagra to be sold without Prescription

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The United States pharmaceutical giant make the announcement late on tuesday, saying it had received authorisation from British regulator following a public consultation. Britain is to become the first country in the world where the erectile dysfunction drug sildenafil will be bought without the need for a doctor’s prescription from 2018, its maker Pfizer said. The hope is that men who haven't antecedently sought-after assistance will currently be more likely to try to to so, though men with heart issues or taking “interfering medicines” can still want a prescription to get sildenafil. Officials conjointly hope that the choice can avoid purchases of viagra on websites operating illegally. “This call is good news for men’s health,” aforesaid mick Foy, group manager in vigilance and risk management of medicines at the Medicines…
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Important information about Vitamin C

Important information about Vitamin C

Articles, Drugs
It is water soluble vitamin and is also known as vitamin C. It is 6 carbon organic acid with structural similarity to glucose.Richest sources of vitamin C are lemons, black currants and other like tomato, green chillies, cabbage, potato and different vegetables.Apart from this human milk is richer in vitamin C ( 25-50mg/L) than cow's milk. Vitamin C therapy is essential in the prevention and treatment of scurvy, however, less florid manifestations of vitamin C deficiency are usually found, especially in the older.it is rarely necessary to prescribe over 100mg daily except early in the treatment of scurvy.It is additionally employed in the treatment of anemia because it enhances the absorption and is often combined with ferrous salts.it is additionally used to Heal wounds and form scar tissue, Repair and…
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