Ebastel contains an active ingredient known as Ebastine and it belongs to a group of drugs known as H1 Receptor antagonist.Ebastine is non-sedating as well as long-acting anti-histamine. Ebastel is used in Allergic rhinitis and chronic idiopathic urticaria.

It is manufactured by Almirall Prodes Pharma Ind Sl.

Ebastel Uses:

It is used for the treatment, of the following diseases, and symptoms:
  • Allergic rhinitis
  • Chronic idiopathic urticaria
  • Seasonal allergic conditions
  • Nasal allergy
  • Chronic itching
  • Eczema/Dermatitis
  • Treat Hives

Mechanism Of Action

Ebastel Contains Ebastin, an antihistamine that works by blocking or inhibiting endogenous histamine produced by the body. Ebastel prevents the binding of histamine to receptors and their activation (activation of histamine receptors on different tissues produces various allergic symptoms, eg nasal discharge).

Side Effects:

Following are some of the side effects associated with the use of ebastel;

  • Dry Mouth
  • Inflammation of the sinus
  • Headache
  • Indigestion
  • Abdominal pain
  • Sore Throat,
  • Sleep Disturbances
  • Bleeding from Nose
  • Palpitation (Very Rare),
  • Nervousness (very rare),
  • Urticaria (Very Rare)
  • Drowsiness (Very rare).

Note:This is not an Complete list of side effects. Please inform your doctor if you experience any adverse reaction to the medication.

Precautions:

Avoid Ebastel If You are/have

  • Hypersensitive (allergic) to ebastine, or to any of the ingredient present in the formulation.
  • Have severe hepatic impairment.
  • Low blood potassium concentrations.
  • Avoid in pregnany and breast feeding without medical advice or by the dentist.
  • It is contraindicated in case of cardiac arrhythmia.
  • Avoid or consult your doctor if you have renal insufficiency.
  • It is contraindicated for children under 12 years of age.

Use In Pregnancy

It is a category B medicine, which means that there are no controlled studies in pregnant women or that animal reproduction studies have shown an adverse effect. Consult Your Doctor before using this medicine in pregnancy.

Interactions:

Certain Drugs when used concomitantly with Ebastel may result in interactions.This may increase your risk for side-effects or cause your drug not to work properly. Following are some drugs that may interact with Ebastel and may increase Plasma Level of Ebastine

  • Ketoconazole
  • Itraconazole
  • Erythromycin
  • Clarithromycin
  • Rifampicin May Decrease The Plasma Level of ebastine.
  • Doesn’t Interact with alcohol
  • Doesn’t Interact With food.

Dosage

The dosage can be adjusted according to the disease, age or symptoms. Follow exactly the instructions.

  • Ebastel can be taken either with food or even without food.
  • Usual Recommended Dose for adult is 10-20 mg Once Daily
  • Usual Recommended Dose for Child age more than 6 years is 5 mg once daily

If you miss a dose of Ebastel, take it as soon as possible. However, if it is almost time to take the next dose, skip the dose and return to your usual schedule. Do not double the dose.

Store medicines at room temperature, away from heat and direct light. Do not freeze drugs unless prescribed in the package leaflet. Keep medicines out of the reach of children.

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