Corex is the combination of two prescription medications such as chlorpheniramine and Codeine.

  • Chlorpheniramine (4mg)
  • Codeine (10mg)
Corex syrup is available in 100 ml and 50 ml.

Chlorpheniramine a first generation antihistamine for the prevention of the symptoms of allergic diseases such as rhinitis and urticaria.

Although chlorpheniramine is not generally approved as an antidepressant or an anxiety medication, it also seems to have these properties.

Codeine is a narcotic analgesic and a cough medicine similar to morphine and hydrocodone. In addition, a small amount of codeine in the body becomes morphine.

The mechanism of action of codeine is unknown; However, like morphine, codeine binds to receptors in the brain (opioid receptors) that are important for the transmission of pain sensation throughout the body and brain. Codeine increases pain tolerance and reduces discomfort, but the pain is still visible to the patient. In addition to pain relief, codeine also causes drowsiness and breathing. Codeine is often combined with acetaminophen (Tylenol) oraspirin for more effective pain relief.

The FDA approved codeine in 1950.

Corex Uses

It is used for relieving
  • Symptoms of sinus pressure,
  • Sinus congestion,
  • Runny nose,
  • Itching of the throat and nose,
  • Watery eyes,
  • Sneezing due to upper respiratory infections,
  • Hay fever and
  • Allergies.

Corex Side Effects

Some adverse effects associated with the use of Corex syrup include

  • Nausea
  • Vomiting
  • Dizziness,
  • Confusion,
  • Anxiety,
  • Sleepiness
  • Constipation,
  • Nausea,
  • Restlessness,
  • Blurred vision,
  • Dry mouth,
  • Decreased coordination,
  • Irritability,
  • Shallow breathing,
  • Hallucinations,
  • Tinnitus,
  • Breathlessness
  • Sweatin
  • Problems with memory or concentration and
  • Trouble urinating.

Corex Syrup Contraindications

This should not be used if you have the following conditions:
  • Hypersensitivity
  • Hypercarbia
  • Acute or severe bronchial asthma
  • Hypersensitivity to codeine
  • Postoperative pain management in children who have undergone tonsillectomy or adenoidectomy
  • Paralytic ileus

Corex Syrup in Pregnancy and Lactation

Corex syrup may not be safe to use during pregnancy. Animal studies have shown adverse effects in the fetus, but there are limited human studies. The benefits of using it in pregnant women may be acceptable despite the risk. While Corex syrup is probably safe to use during breastfeeding. Limited human data suggest that the drug poses no significant risk to the baby. Higher doses or prolonged use of Corex syrup may cause drowsiness and other effects on the baby. Consult your doctor.

Drugs Interactions

Corex Syrup may interact with the following drugs and products:
  • Antianxiety agents
  • Alcohol
  • Antiemetics
  • Antipsychotics
  • Antihistamines
  • Anticholinergics

Tell your doctor about all the medicines, vitamins and herbal supplements you use to help your doctor help you prevent or control drug interactions.

Corex Dosage

  • Usual Dose for Adult: 5ml;
  • Usual dose for child 6-12 yrs: 2.5ml;
  • Dose for child 2-6 yrs: 1.25ml.
  • All four times a day.

You can take this medication orally with or without food. Usually, this medication is recommended for a short time until symptoms resolve. Do not take it for more than 7 days in a row.

Related Article: Important Information About Diphenhydramine (Vivinox) 

 

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