Betamethasone (Brand: Celestamine) belong to a group of drugs known as corticosteroid.It is manufactured and marketed by Schering Plough Limited (Under – Merck Sharp and Dohme LLC).

Celestamine tablets contain a medicinal mixture of two components betamethasone and dexchlorpheniramine. The composition of these two components in each tablet is below:

  • Betamethasone: 250 mcg per tablet
  • Dexchlorpheniramine Maleate – 2 mg per tablet

It is used for allergic disorders, itching or rash, dermatitis, ataxia telangiectasia, psoriasis of the scalp,ulcerative colitis ,arthritis, phimosis, and other diseases.

Celestamine Uses

Celestamine Tablet is used to treat, control, prevent and improve the following diseases, conditions and symptoms:
  • Breathing disorders
  • Itch or rash
  • Allergic disorders
  • Skin inflammation
  • Ataxia telangiectasia
  • Cerebral edema
  • Scalp psoriasis
  • Arthritis
  • Ulcerative colitis
  • Phimosis
  • Hematologic disorders such as Acquired(autoimmune) hemolytic anemia, Diamond-Blackfan anemia, idiopathic thrombocytopenic purpura in adults.
  • Blood disorders.

Celestamine Mechanism

Celestamine is the combination of anti-inflammatory and anti-allergic medications.

Betamethasone is a drug with corticosteroids, sometimes referred to as steroid. Steroids reduce the amount of inflammatory chemicals your body produces. They also reduce the body’s natural immune response, which helps to control inflammation.

while dexchlorophenamine maleate has antihistamine properties.

Celestamine Side Effects

The more common side effects that can occur with celestamine include:

  • Problems with your vision;
  • swelling, rapid weight gain, feeling short of breath;
  • severe depression, unusual thoughts or behavior, seizure (convulsions);
  • Bloody or tarry stools,
  • Coughing up blood;
  • Sedation and drowsiness
  • Fluid and electrolyte disturbance in body
  • Muscle weakness, loss of muscle mass, tendon rupture.
  • Congestive heart failure in susceptible patients
  • Osteoporosis, pathological fractures
  • Peptic ulcers, irregular bowels, nausea, vomiting
  • Skin discoloration (Blue skin color).
  • Impaired healing of wounds
  • Swelling of your face, lips, tongue, or throat.
  • Seizure
  • Abdominal distention.
  • Thin and fragile skin.
  • Increased sweating, urticaria.
  • Vertigo, headaches.
  • Euphoria, mood swings, depression.
  • Menstrual irregularities
  • Infection. Signs may include:cough, fever, chills.


  • Before you taking Celestamine tell your doctor If you have an allergy to betamethasone or any other part of betamethasone preparations.
  • Tell you Doctor If you are allergic to any drugs like this one, any other drugs, foods, or other substances. Tell your doctor about the allergy and what signs you had, like rash; hives; itching; shortness of breath; wheezing; cough; swelling of face, lips, tongue, or throat; or any other signs.
  • Celestamine is not suitable for infants.
  • Before taking Celestamine Tell Your Doctor If you have any of these health problems: A fungal infection or malaria infection in the brain and herpes infection of the eye.
  • If you have nerve problems in the eye.
  • Tell your doctor and pharmacist about all of your drugs (prescription or OTC, natural products, vitamins) and health problems. You must check to make sure that it is safe for you to take betamethasone oral solution with all of your drugs and health problems. Do not start, stop, or change the dose of any drug without checking with your doctor.
  • Should not use celestamine for prolonged time.

Celestamine In Pregnancy & Breastfeeding

The FDA has assigned pregnancy category C betamethasone. Studies in animals have shown evidence of teratogenicity when oral corticosteroids are administered or potent steroids are administered topically. There is no controlled data in human pregnancy. Betamethasone has been shown to cross the placenta. Betamethasone is recommended only during pregnancy when there are no alternatives and the benefits outweigh the risks.

Celestamine is not safe to take if you are breast-feeding or intending to start breastfeeding. The corticosteroid can damage the fetus or a baby. This can also disrupt the normal growth of a newborn baby. Always consult a health care professional before using Celestamine if you are breast-feeding a baby.

Celestamine Dosage

The usual recommended dose of Celestamine for adults is 2 to 6 tablets per day. As the patient improves, the dosage should be gradually reduced to the minimum required. The drug should stop whenever possible.

Your doctor will determine the right dose for you based on your individual needs. Your overall health can affect your dose. Tell your doctor about all the health conditions you have before your doctor or nurse gives you the medicine.


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