Motilium (Domperidone) Uses

Motilium is a medication that increases the movements or contractions of the stomach and intestine. Domperidone is additionally used to treat nausea and emesis caused by other medicine used to treat parkinson’s Diseases uch as levodopa,pramipexole and apomorphine.

Mechanism Of Action Of Motilium

  • Domperidone are associated with its dopamine receptor obstruction activity at both the receptor trigger zone and at the gastric level. it’s robust affinities for the D2 and D3 dopamine receptors, that are found within the chemoreceptor trigger zone, placed simply outside the blood brain barrier, which – among others – regulates nausea and emesis

Motilium Contraindicatio

Motilium Side effects :

Side effects related to domperidone include

  • Abdominal cramps,
  • Dry mouth,
  • Diarrhea,
  • Nausea,
  • Rash,
  • Itching,
  • Hives,
  • Breast enlargement,
  • Galactorrhea,
  • Breast pain/tenderness,
  • Hypogonadism,
  • Gynecomastia, and
  • Menstrual irregularities).


Other side effects include

  • insomnia,
  • Drowsiness,
  • Akathisia,
  • Restlessness,
  • Lassitude,
  • Fatigue,
  • Extrapyramidal symptoms,
  • dystonia,
  • Parkinsonian symptoms,
  • Tardive dyskinesia, and
  • Depression.

Domperidone (Motlium)  Use in Pregnancy :

  • The safety of this medication to be used throughout pregnancy has not been established. It mustn’t be utilized in pregnant women unless the potential advantages to the mother outweigh any risks to the developing baby. It should only be used if the drugs is considered essential by your doctor. ask your doctor for any recommendation.

Motilium Dosage information:

  • Take this medication orally as prescribed usually half-hour before meals and at time of day.The dose for adults and for young people aged over 16 years is 10 mg (one tablet) up to three times a day. don’t take more than 3 doses in any 24-hour period. If it’s been prescribed for a toddler, the dose are going to be printed on the label of the pack to remind you what the doctor said. don’t increase your dose or take this more typically than directed. Your condition won’t improve any faster however the chance of side effects will be increased.

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